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The map label for this gene is fur [H]

Identifier: 238920780

GI number: 238920780

Start: 2789723

End: 2790037

Strand: Direct

Name: fur [H]

Synonym: NT01EI_2899

Alternate gene names: 238920780

Gene position: 2789723-2790037 (Clockwise)

Preceding gene: 238920779

Following gene: 238920783

Centisome position: 73.18

GC content: 56.83

Gene sequence:

>315_bases
ATGGGCGAGGAGATCGGTCTGGCGACTGTATACCGCGTACTCAACCAGTTTGACGATGCCGGCATCGTGACCCGCCATAA
CTTTGAGGGCGGTAAATCGGTTTTTGAGCTGACCCAGCAGCACCACCACGATCACCTGATCTGCCTGGACTGCGGCAAGG
TCATCGAATTCAGCGATGAGTCCATTGAGAAGCGTCAGCGCGAAATCGCGAAAAAGCACGGCATCCAGCTGACCAACCAC
AGCCTGTATCTCTACGGCCACTGCGCCGAAGGCGACTGCCGTAGCGATGAGACCCTGCACGATGAAAAGGCCTGA

Upstream 100 bases:

>100_bases
CCTTAAAGTCACGCTTCCCCGTCTCAAGATTCTGGAAGTACTGCAAGATCCTACGTGCCATCATGTCAGTGCTGAAGACT
TGTACAAGAAGCTAATCGAT

Downstream 100 bases:

>100_bases
GTGACCTGGCGCCCACAGCAGGCGACGACGCGGCCCAGCGGGGCCGTTTTTTTCCCTGCGCGACAGCGGGCAAAAAAAAG
GTTCATCGCGCTTTACCGGG

Product: ferric uptake regulator

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 104; Mature: 103

Protein sequence:

>104_residues
MGEEIGLATVYRVLNQFDDAGIVTRHNFEGGKSVFELTQQHHHDHLICLDCGKVIEFSDESIEKRQREIAKKHGIQLTNH
SLYLYGHCAEGDCRSDETLHDEKA

Sequences:

>Translated_104_residues
MGEEIGLATVYRVLNQFDDAGIVTRHNFEGGKSVFELTQQHHHDHLICLDCGKVIEFSDESIEKRQREIAKKHGIQLTNH
SLYLYGHCAEGDCRSDETLHDEKA
>Mature_103_residues
GEEIGLATVYRVLNQFDDAGIVTRHNFEGGKSVFELTQQHHHDHLICLDCGKVIEFSDESIEKRQREIAKKHGIQLTNHS
LYLYGHCAEGDCRSDETLHDEKA

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. Regulates the expression of several outer-membrane proteins including the iron transport operon [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=103, Percent_Identity=91.2621359223301, Blast_Score=196, Evalue=3e-52,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 11864; Mature: 11733

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEEIGLATVYRVLNQFDDAGIVTRHNFEGGKSVFELTQQHHHDHLICLDCGKVIEFSDE
CCCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHCCCCEEEEECCCEEECCCH
SIEKRQREIAKKHGIQLTNHSLYLYGHCAEGDCRSDETLHDEKA
HHHHHHHHHHHHCCCEECCCEEEEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GEEIGLATVYRVLNQFDDAGIVTRHNFEGGKSVFELTQQHHHDHLICLDCGKVIEFSDE
CCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHCCCCEEEEECCCEEECCCH
SIEKRQREIAKKHGIQLTNHSLYLYGHCAEGDCRSDETLHDEKA
HHHHHHHHHHHHCCCEECCCEEEEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9055816 [H]