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The map label for this gene is carI [H]

Identifier: 238920761

GI number: 238920761

Start: 2768538

End: 2769203

Strand: Reverse

Name: carI [H]

Synonym: NT01EI_2879

Alternate gene names: 238920761

Gene position: 2769203-2768538 (Counterclockwise)

Preceding gene: 238920763

Following gene: 238920759

Centisome position: 72.64

GC content: 48.65

Gene sequence:

>666_bases
ATGTTTGAGATTTTTGATGTTGACTATCAGTCTCTGTCAAGAACGGCATCAACAGAGCTATTTTCCCTGCGTAAGGGGAC
GTTTAAGGATCGGCTTAACTGGGCGGTAACCTGCAGCGATGGGATGGAGTTTGATGAGTATGACAGCAAACATACAATCT
ATCTGTTGGGAGTAAAGGATAACGATGTGGTGTGCAGCGTACGCTTAATTGAGACCTGCCATCACAATATGATTGTCGGC
ACGTTTTTCCGCTACTTTGAGAAAGGTGAGATCCCGGCCAGCAGCCAGTTTTTTGAATCTAGCCGCTTCTTTGTCGATAA
GCGTCGCGCCCGAACTCTGCTGGGTAATCAATACCCGCTGTGTCATCTACTGTTTCTCGCTATGATTAACTATACGATGG
CCTCTGGTCACCGCGGTATTTATACGATTGTCAGCCATTCGATGCTGCGGATTTTGACCCGTTCCGGCTGGAATATTACC
GTGGTGGAGCGAGGGGTGTCGGAGAAGGTGCAGGATATCTATCTGGTCTATTTACCGACGGATGCAGCTAATCAGCGTCT
GCTGATCGAGCGGATTAATCAGGATCAGCCTTTTGATGAGGAGGCTCTGCAGAGTTGGCCCATGGTACTGAAATCCGCCG
ATGCGCTCAACCTTCAATCGGCTTAA

Upstream 100 bases:

>100_bases
GGATTGTATTGGCACACGTCAGCGTAGGATAAGGCACCGTTTGGCTTATGCTGGGCTACGTGGTAGGCCTGTACACAGGC
AGGGCGTTAAGGGACAGAAA

Downstream 100 bases:

>100_bases
TCAGCTGCAGTTCAACGCCAAGCCGGATTGCGTGCTTGGCGTTTAATACCCCCAGCTTTTTGACAACATTACCAATGTGA
AATTTGACTGTGCCAGTTTT

Product: autoinducer synthase

Products: NA

Alternate protein names: Autoinducer synthesis protein CarI [H]

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MFEIFDVDYQSLSRTASTELFSLRKGTFKDRLNWAVTCSDGMEFDEYDSKHTIYLLGVKDNDVVCSVRLIETCHHNMIVG
TFFRYFEKGEIPASSQFFESSRFFVDKRRARTLLGNQYPLCHLLFLAMINYTMASGHRGIYTIVSHSMLRILTRSGWNIT
VVERGVSEKVQDIYLVYLPTDAANQRLLIERINQDQPFDEEALQSWPMVLKSADALNLQSA

Sequences:

>Translated_221_residues
MFEIFDVDYQSLSRTASTELFSLRKGTFKDRLNWAVTCSDGMEFDEYDSKHTIYLLGVKDNDVVCSVRLIETCHHNMIVG
TFFRYFEKGEIPASSQFFESSRFFVDKRRARTLLGNQYPLCHLLFLAMINYTMASGHRGIYTIVSHSMLRILTRSGWNIT
VVERGVSEKVQDIYLVYLPTDAANQRLLIERINQDQPFDEEALQSWPMVLKSADALNLQSA
>Mature_221_residues
MFEIFDVDYQSLSRTASTELFSLRKGTFKDRLNWAVTCSDGMEFDEYDSKHTIYLLGVKDNDVVCSVRLIETCHHNMIVG
TFFRYFEKGEIPASSQFFESSRFFVDKRRARTLLGNQYPLCHLLFLAMINYTMASGHRGIYTIVSHSMLRILTRSGWNIT
VVERGVSEKVQDIYLVYLPTDAANQRLLIERINQDQPFDEEALQSWPMVLKSADALNLQSA

Specific function: Required for the synthesis of OHHL (N-(3-oxohexanoyl)-L- homoserine lactone), an autoinducer molecule which binds to CarR and thus acts in the control of the biosynthesis of carbapenem antibiotics [H]

COG id: COG3916

COG function: function code TQ; N-acyl-L-homoserine lactone synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the autoinducer synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016181
- InterPro:   IPR001690
- InterPro:   IPR018311 [H]

Pfam domain/function: PF00765 Autoind_synth [H]

EC number: =2.3.1.184 [H]

Molecular weight: Translated: 25536; Mature: 25536

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00949 AUTOINDUCERS_SYNTH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEIFDVDYQSLSRTASTELFSLRKGTFKDRLNWAVTCSDGMEFDEYDSKHTIYLLGVKD
CCEEEECCHHHHHHHHHHHHHHHHCCCHHHHCCEEEEECCCCCCCCCCCCEEEEEEEECC
NDVVCSVRLIETCHHNMIVGTFFRYFEKGEIPASSQFFESSRFFVDKRRARTLLGNQYPL
CCEEEEHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCH
CHLLFLAMINYTMASGHRGIYTIVSHSMLRILTRSGWNITVVERGVSEKVQDIYLVYLPT
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCHHCCCEEEEEEECC
DAANQRLLIERINQDQPFDEEALQSWPMVLKSADALNLQSA
CCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MFEIFDVDYQSLSRTASTELFSLRKGTFKDRLNWAVTCSDGMEFDEYDSKHTIYLLGVKD
CCEEEECCHHHHHHHHHHHHHHHHCCCHHHHCCEEEEECCCCCCCCCCCCEEEEEEEECC
NDVVCSVRLIETCHHNMIVGTFFRYFEKGEIPASSQFFESSRFFVDKRRARTLLGNQYPL
CCEEEEHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCH
CHLLFLAMINYTMASGHRGIYTIVSHSMLRILTRSGWNITVVERGVSEKVQDIYLVYLPT
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCHHCCCEEEEEEECC
DAANQRLLIERINQDQPFDEEALQSWPMVLKSADALNLQSA
CCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7968529 [H]