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The map label for this gene is gltA [H]

Identifier: 238920755

GI number: 238920755

Start: 2763537

End: 2764820

Strand: Direct

Name: gltA [H]

Synonym: NT01EI_2875

Alternate gene names: 238920755

Gene position: 2763537-2764820 (Clockwise)

Preceding gene: 238920735

Following gene: 238920757

Centisome position: 72.49

GC content: 55.92

Gene sequence:

>1284_bases
ATGGCAGAGAAAAAAGCAACGCTGACGGTGGACGCAGAGCATATAGAGCTCGATGTCCTCGAGGGGACGTTAGGAAATAA
AGAGATCGATATTCGCAAACTGGGTAGCCAGGGCTACTTCACCTTTGACCCGGGATTTACCTCTACGGCCTCCTGCGAAT
CTAAAATTACCTATATTGACGGTGATGAAGGGATCCTACTGCACCGCGGCTATCCTATCGATCAGTTAGCCAAAAACTCC
TCTTTCCTGGAAGTTTGCTACATTCTGCTGTATGGTGAGACGCCCGATCAGGCGGAATACGATGTATTCAAGAATACCGT
CACCCGCCACACCATGATCCATGAGCAGATCACCCGTCTGCTGCAGGGGTTCCGCCGCGACTCCCACCCGATGGCCGTCA
TGTGTGGCGTTACCGGAGCGCTGGCCGCGTTTTACCATGACTCGCTGGATATCAGCAACGAGCGCCACCGTGAGATCGCC
GCGTTCCGCCTGCTCTCCAAGATGCCGACCGTCGCAGCCATGTGCTACAAATACTCGCTGGGACAACCCTTTATCTATCC
ACAAAATAATCTCTCCTACGCCGGTAACTTCCTACGCATGATGTTCGCGACACCGTGCGAAGAGTACGTGGTCAATCCGG
TTCTGGAACGCGCCATGGATCGCATCCTGATCCTGCACGCCGACCATGAGCAGAACGCCTCCACCTCGACCGTACGCACC
GCTGGCTCCTCCGGAGCCAATCCATTCGCCTGCATCGCCGCCGGTATTGCCTCGCTGTGGGGGCCCGCCCACGGCGGCGC
TAACGAGGCCTGCCTGAAGATGCTGGAAGAGATTAGCCGCGTGGAGCACATTCCAGCCTTTATTAAGCGCGCCAAGGATA
AAAATGATTCGTTCCGTCTGATGGGCTTTGGCCATCGGGTCTATAAAAACTACGATCCGCGGGCCACCGTGATGCGCGAA
ACCTGCCATGAAGTGCTCAATGAACTGGGCATGAATGACAATCTGCTGGAGGTCGCCCTGGAGCTGGAGCACATCGCCCT
GAACGATCCCTACTTCATCGAGAAAAAGCTCTACCCCAACGTCGACTTCTACTCCGGTATCATCCTGAAGGCCATGGGGA
TCCCCTCCAGCATGTTCACCGTCATTTTCGCGATTGCGCGTACCGTCGGCTGGATAGCCCACTGGAATGAAATGCACGAG
GATGGTCTGAAGATCGCCCGCCCGCGCCAGCTGTATACCGGCTATACGCGCCGTGACTTCAGCTCACGGCTGAACCAGCG
TTAA

Upstream 100 bases:

>100_bases
GTAGGGCAGGATGCCGATCATCACATGCCGGGAAAGCTTAGCACGCTGCACCCAGTACATAGTTAATGAGTCTAAAAATA
GCAGTACCAAAGGAGGCTGT

Downstream 100 bases:

>100_bases
TCATTCCCCGGCGGGAGCGGCTCCCGCCGGTTTTCGCGTTACCCGATGTGTCCTCCAACCCACCCTGACAGCCCGGACAG
CCGTAAAACGGACGCGACGC

Product: type II citrate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 427; Mature: 426

Protein sequence:

>427_residues
MAEKKATLTVDAEHIELDVLEGTLGNKEIDIRKLGSQGYFTFDPGFTSTASCESKITYIDGDEGILLHRGYPIDQLAKNS
SFLEVCYILLYGETPDQAEYDVFKNTVTRHTMIHEQITRLLQGFRRDSHPMAVMCGVTGALAAFYHDSLDISNERHREIA
AFRLLSKMPTVAAMCYKYSLGQPFIYPQNNLSYAGNFLRMMFATPCEEYVVNPVLERAMDRILILHADHEQNASTSTVRT
AGSSGANPFACIAAGIASLWGPAHGGANEACLKMLEEISRVEHIPAFIKRAKDKNDSFRLMGFGHRVYKNYDPRATVMRE
TCHEVLNELGMNDNLLEVALELEHIALNDPYFIEKKLYPNVDFYSGIILKAMGIPSSMFTVIFAIARTVGWIAHWNEMHE
DGLKIARPRQLYTGYTRRDFSSRLNQR

Sequences:

>Translated_427_residues
MAEKKATLTVDAEHIELDVLEGTLGNKEIDIRKLGSQGYFTFDPGFTSTASCESKITYIDGDEGILLHRGYPIDQLAKNS
SFLEVCYILLYGETPDQAEYDVFKNTVTRHTMIHEQITRLLQGFRRDSHPMAVMCGVTGALAAFYHDSLDISNERHREIA
AFRLLSKMPTVAAMCYKYSLGQPFIYPQNNLSYAGNFLRMMFATPCEEYVVNPVLERAMDRILILHADHEQNASTSTVRT
AGSSGANPFACIAAGIASLWGPAHGGANEACLKMLEEISRVEHIPAFIKRAKDKNDSFRLMGFGHRVYKNYDPRATVMRE
TCHEVLNELGMNDNLLEVALELEHIALNDPYFIEKKLYPNVDFYSGIILKAMGIPSSMFTVIFAIARTVGWIAHWNEMHE
DGLKIARPRQLYTGYTRRDFSSRLNQR
>Mature_426_residues
AEKKATLTVDAEHIELDVLEGTLGNKEIDIRKLGSQGYFTFDPGFTSTASCESKITYIDGDEGILLHRGYPIDQLAKNSS
FLEVCYILLYGETPDQAEYDVFKNTVTRHTMIHEQITRLLQGFRRDSHPMAVMCGVTGALAAFYHDSLDISNERHREIAA
FRLLSKMPTVAAMCYKYSLGQPFIYPQNNLSYAGNFLRMMFATPCEEYVVNPVLERAMDRILILHADHEQNASTSTVRTA
GSSGANPFACIAAGIASLWGPAHGGANEACLKMLEEISRVEHIPAFIKRAKDKNDSFRLMGFGHRVYKNYDPRATVMRET
CHEVLNELGMNDNLLEVALELEHIALNDPYFIEKKLYPNVDFYSGIILKAMGIPSSMFTVIFAIARTVGWIAHWNEMHED
GLKIARPRQLYTGYTRRDFSSRLNQR

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0372

COG function: function code C; Citrate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the citrate synthase family [H]

Homologues:

Organism=Homo sapiens, GI38327625, Length=390, Percent_Identity=25.8974358974359, Blast_Score=106, Evalue=4e-23,
Organism=Escherichia coli, GI1786939, Length=427, Percent_Identity=83.6065573770492, Blast_Score=766, Evalue=0.0,
Organism=Escherichia coli, GI1786527, Length=370, Percent_Identity=32.1621621621622, Blast_Score=166, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI17555174, Length=397, Percent_Identity=26.1964735516373, Blast_Score=110, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6319850, Length=355, Percent_Identity=27.887323943662, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6324328, Length=387, Percent_Identity=26.0981912144703, Blast_Score=106, Evalue=8e-24,
Organism=Saccharomyces cerevisiae, GI6325257, Length=368, Percent_Identity=25.2717391304348, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24640124, Length=403, Percent_Identity=25.8064516129032, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24640126, Length=403, Percent_Identity=25.8064516129032, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI21356863, Length=354, Percent_Identity=25.1412429378531, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: 624 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016142
- InterPro:   IPR016143
- InterPro:   IPR002020
- InterPro:   IPR016141
- InterPro:   IPR019810
- InterPro:   IPR010953 [H]

Pfam domain/function: PF00285 Citrate_synt [H]

EC number: =2.3.3.1 [H]

Molecular weight: Translated: 48220; Mature: 48089

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00480 CITRATE_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEKKATLTVDAEHIELDVLEGTLGNKEIDIRKLGSQGYFTFDPGFTSTASCESKITYID
CCCCCEEEEEEHHHEEEEEEECCCCCCEEEHEECCCCCEEEECCCCCCCCCCCCEEEEEE
GDEGILLHRGYPIDQLAKNSSFLEVCYILLYGETPDQAEYDVFKNTVTRHTMIHEQITRL
CCCCEEEECCCCHHHHHCCCCHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LQGFRRDSHPMAVMCGVTGALAAFYHDSLDISNERHREIAAFRLLSKMPTVAAMCYKYSL
HHHHCCCCCCEEEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHC
GQPFIYPQNNLSYAGNFLRMMFATPCEEYVVNPVLERAMDRILILHADHEQNASTSTVRT
CCCEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHEE
AGSSGANPFACIAAGIASLWGPAHGGANEACLKMLEEISRVEHIPAFIKRAKDKNDSFRL
CCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
MGFGHRVYKNYDPRATVMRETCHEVLNELGMNDNLLEVALELEHIALNDPYFIEKKLYPN
EECCHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHEECCCCEEEEHCCCCC
VDFYSGIILKAMGIPSSMFTVIFAIARTVGWIAHWNEMHEDGLKIARPRQLYTGYTRRDF
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCHHHHH
SSRLNQR
HHHHCCC
>Mature Secondary Structure 
AEKKATLTVDAEHIELDVLEGTLGNKEIDIRKLGSQGYFTFDPGFTSTASCESKITYID
CCCCEEEEEEHHHEEEEEEECCCCCCEEEHEECCCCCEEEECCCCCCCCCCCCEEEEEE
GDEGILLHRGYPIDQLAKNSSFLEVCYILLYGETPDQAEYDVFKNTVTRHTMIHEQITRL
CCCCEEEECCCCHHHHHCCCCHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LQGFRRDSHPMAVMCGVTGALAAFYHDSLDISNERHREIAAFRLLSKMPTVAAMCYKYSL
HHHHCCCCCCEEEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHC
GQPFIYPQNNLSYAGNFLRMMFATPCEEYVVNPVLERAMDRILILHADHEQNASTSTVRT
CCCEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHEE
AGSSGANPFACIAAGIASLWGPAHGGANEACLKMLEEISRVEHIPAFIKRAKDKNDSFRL
CCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
MGFGHRVYKNYDPRATVMRETCHEVLNELGMNDNLLEVALELEHIALNDPYFIEKKLYPN
EECCHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHEECCCCEEEEHCCCCC
VDFYSGIILKAMGIPSSMFTVIFAIARTVGWIAHWNEMHEDGLKIARPRQLYTGYTRRDF
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCHHHHH
SSRLNQR
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]