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The map label for this gene is aroC

Identifier: 238920642

GI number: 238920642

Start: 2653189

End: 2654274

Strand: Reverse

Name: aroC

Synonym: NT01EI_2754

Alternate gene names: 238920642

Gene position: 2654274-2653189 (Counterclockwise)

Preceding gene: 238920643

Following gene: 238920641

Centisome position: 69.62

GC content: 63.26

Gene sequence:

>1086_bases
ATGGCGGGAAACAGCATTGGCCAGGTATTCAGAGTAACCACCTTCGGCGAGTCACACGGTGCGGCGCTGGGCTGCATTGT
GGACGGCGTTCCGCCGGGAATGGCGCTGAGTGAGGCGGATCTGCAGCACGATCTCGATCGCCGTCGCCCCGGCGCGTCGC
GCTATACCACGGCGCGGCGTGAGGCGGACCGGGTGCGGATCCTTTCGGGTGTCTTTGAGGGAGTGACCACCGGTACCAGT
ATTGGACTGCTGATCGAGAACACCGATCAGCGCTCGCAGGATTATAGCGCCATCAAGGATCTGTTTCGCCCGGGCCACGC
CGACTACAGCTATGAGCAGAAGTATGGACTGCGCGACTACCGGGGCGGTGGACGCTCTTCGGCGCGGGAAACCGCGATGC
GCGTCGCCGCCGGTGCGATCGCTAAAAAATACCTTCAGCAGCAGCATGGCATCGTTATCCGCGCCTGCCTGAGCCGGATG
GGCGATATCGTCTGCCGTCAGTACGACTGGGCGCAGGTAGAGCAGAATCCCTTCTTCTGTCCTGATGCACAGCAGCTGGA
GGCGCTGGATGCCCTGATGCGCGATCTGAAGAAGTGCGGAGACTCGATCGGCGCCGAAGTGACGGTGATGGCGACCGGGG
TTCCCCCCGGACTGGGCGATCCGGTCTTCGATCGTCTGGACGCCGACCTGGCCCATGCGCTGATGAGCATCAATGCAGTT
AAGGGTGTAGAGATAGGCGATGGCTTTGCGGTGGTGGGGCAGCGTGGCAGCGAGCATCGCGATGAAATCAGTCCGTCGGG
ATTTCTCAGCAATCATGCCGGTGGCATTCTGGGCGGGATCAGCAGCGGTCAGCCGCTACTGGCGCGCCTGGCGCTAAAGC
CGACGTCAAGCATTATGGTGCCGGGGCAGACCATTACCCGCGCCGGCGAGGCGACGACCATAGTCACCCACGGCCGTCAC
GACCCCTGCGTGGGGATCCGGGCGGTGCCGATCGCCGAGGCAATGATGGCACTGGTGCTGATGGATCATCTGCTGCGCCA
GCGTGCGCAGTGTGCGGATGTCGCCTGTACGGTGCCACGCTGGTAA

Upstream 100 bases:

>100_bases
TTTACCGCAGCTGACCGCGGGGCAGGTGGCGGGCCTCCCCCTTTACCGGATGCAGAGACAGGCAGTCCCCTGATGGCGTC
AGGGCAACCAGGAGAGTGAC

Downstream 100 bases:

>100_bases
AGGAGTGGTCACAGTGAGTAAATGTGCGTGGTTATGGCTGGCGGCGCTGTGCGCGTTGCCGGCGCTGGCTCAGACGCCCT
GGCAACGCATTACCCAACCG

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MAGNSIGQVFRVTTFGESHGAALGCIVDGVPPGMALSEADLQHDLDRRRPGASRYTTARREADRVRILSGVFEGVTTGTS
IGLLIENTDQRSQDYSAIKDLFRPGHADYSYEQKYGLRDYRGGGRSSARETAMRVAAGAIAKKYLQQQHGIVIRACLSRM
GDIVCRQYDWAQVEQNPFFCPDAQQLEALDALMRDLKKCGDSIGAEVTVMATGVPPGLGDPVFDRLDADLAHALMSINAV
KGVEIGDGFAVVGQRGSEHRDEISPSGFLSNHAGGILGGISSGQPLLARLALKPTSSIMVPGQTITRAGEATTIVTHGRH
DPCVGIRAVPIAEAMMALVLMDHLLRQRAQCADVACTVPRW

Sequences:

>Translated_361_residues
MAGNSIGQVFRVTTFGESHGAALGCIVDGVPPGMALSEADLQHDLDRRRPGASRYTTARREADRVRILSGVFEGVTTGTS
IGLLIENTDQRSQDYSAIKDLFRPGHADYSYEQKYGLRDYRGGGRSSARETAMRVAAGAIAKKYLQQQHGIVIRACLSRM
GDIVCRQYDWAQVEQNPFFCPDAQQLEALDALMRDLKKCGDSIGAEVTVMATGVPPGLGDPVFDRLDADLAHALMSINAV
KGVEIGDGFAVVGQRGSEHRDEISPSGFLSNHAGGILGGISSGQPLLARLALKPTSSIMVPGQTITRAGEATTIVTHGRH
DPCVGIRAVPIAEAMMALVLMDHLLRQRAQCADVACTVPRW
>Mature_360_residues
AGNSIGQVFRVTTFGESHGAALGCIVDGVPPGMALSEADLQHDLDRRRPGASRYTTARREADRVRILSGVFEGVTTGTSI
GLLIENTDQRSQDYSAIKDLFRPGHADYSYEQKYGLRDYRGGGRSSARETAMRVAAGAIAKKYLQQQHGIVIRACLSRMG
DIVCRQYDWAQVEQNPFFCPDAQQLEALDALMRDLKKCGDSIGAEVTVMATGVPPGLGDPVFDRLDADLAHALMSINAVK
GVEIGDGFAVVGQRGSEHRDEISPSGFLSNHAGGILGGISSGQPLLARLALKPTSSIMVPGQTITRAGEATTIVTHGRHD
PCVGIRAVPIAEAMMALVLMDHLLRQRAQCADVACTVPRW

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=361, Percent_Identity=80.0554016620499, Blast_Score=577, Evalue=1e-166,
Organism=Saccharomyces cerevisiae, GI6321290, Length=367, Percent_Identity=44.6866485013624, Blast_Score=300, Evalue=2e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_EDWI9 (C5BAF2)

Other databases:

- EMBL:   CP001600
- RefSeq:   YP_002934157.1
- ProteinModelPortal:   C5BAF2
- GeneID:   7959964
- GenomeReviews:   CP001600_GR
- KEGG:   eic:NT01EI_2754
- OMA:   SRFTTQR
- ProtClustDB:   PRK05382
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 38713; Mature: 38581

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGNSIGQVFRVTTFGESHGAALGCIVDGVPPGMALSEADLQHDLDRRRPGASRYTTARR
CCCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHH
EADRVRILSGVFEGVTTGTSIGLLIENTDQRSQDYSAIKDLFRPGHADYSYEQKYGLRDY
HHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCHHHHCCCHHC
RGGGRSSARETAMRVAAGAIAKKYLQQQHGIVIRACLSRMGDIVCRQYDWAQVEQNPFFC
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHCCCCCCC
PDAQQLEALDALMRDLKKCGDSIGAEVTVMATGVPPGLGDPVFDRLDADLAHALMSINAV
CCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGDGFAVVGQRGSEHRDEISPSGFLSNHAGGILGGISSGQPLLARLALKPTSSIMV
CCCEECCCEEEECCCCCCHHHHCCCCCCHHCCCCCEECCCCCCCHHHHHHHCCCCCCEEE
PGQTITRAGEATTIVTHGRHDPCVGIRAVPIAEAMMALVLMDHLLRQRAQCADVACTVPR
CCHHHHCCCCCEEEEECCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
W
C
>Mature Secondary Structure 
AGNSIGQVFRVTTFGESHGAALGCIVDGVPPGMALSEADLQHDLDRRRPGASRYTTARR
CCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHH
EADRVRILSGVFEGVTTGTSIGLLIENTDQRSQDYSAIKDLFRPGHADYSYEQKYGLRDY
HHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCHHHHCCCHHC
RGGGRSSARETAMRVAAGAIAKKYLQQQHGIVIRACLSRMGDIVCRQYDWAQVEQNPFFC
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHCCCCCCC
PDAQQLEALDALMRDLKKCGDSIGAEVTVMATGVPPGLGDPVFDRLDADLAHALMSINAV
CCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGDGFAVVGQRGSEHRDEISPSGFLSNHAGGILGGISSGQPLLARLALKPTSSIMV
CCCEECCCEEEECCCCCCHHHHCCCCCCHHCCCCCEECCCCCCCHHHHHHHCCCCCCEEE
PGQTITRAGEATTIVTHGRHDPCVGIRAVPIAEAMMALVLMDHLLRQRAQCADVACTVPR
CCHHHHCCCCCEEEEECCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
W
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA