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The map label for this gene is yfbQ [H]

Identifier: 238920575

GI number: 238920575

Start: 2582246

End: 2583466

Strand: Direct

Name: yfbQ [H]

Synonym: NT01EI_2687

Alternate gene names: 238920575

Gene position: 2582246-2583466 (Clockwise)

Preceding gene: 238920572

Following gene: 238920576

Centisome position: 67.73

GC content: 57.82

Gene sequence:

>1221_bases
ATGTCTCCGATCGAAAAATCCCACAAGCTGGACCACGTATGCTACGACATCCGCGGCCCGGTGCTCAAAGAAGCCAAGCG
GCTGGAAGAAGAAGGCAATAAAGTCCTCAAGCTGAACATTGGCAACCCGGCCCCCTTCGGCTTTGAAGCGCCTGACGAAA
TTCTGGTCGACGTGATCCGTAACCTACCGACGGCGCAGGGCTACAGCGACTCCAAAGGACTCTATTCGGCGCGCAAGGCC
ATTATGCAGCACTACCAGGCCCACGACATCCGCGACGTCAGCGTCGAGGACATCTACATCGGCAACGGCGTCTCCGAGCT
TATCGTGCAGTCCATGCAGGCACTGCTCAACACCAATGACGAAATGCTGGTTCCGGCCCCAGACTACCCGCTGTGGACCG
CTGCCGTTGCGCTCTCCGGCGGCAACGCGGTTCACTACCGCTGCGATGAGCAGGCGGACTGGTTCCCCGACATTGACGAT
ATCCGTAGCAAAATCACCCCGCGCACCCGCGGCATCGTCATCATCAACCCCAATAATCCGACCGGTGCTGTCTACAGCAA
GGCGCTGTTGGAGCAGATTGTGGATCTGGCCCGCGAACATAACCTGATCATCTTTGCCGATGAGATCTACGACAAGATCC
TGTATGACGATGCGCAGCATATATCCATTGCCACGCTGGCGCCGGATCTGCTGGTGATCACCTTTAACGGCCTCTCCAAA
ACCTACCGCGTGGCCGGTTTCCGTCAGGGCTGGATGGTGCTCAGCGGGCCGAAAAAGCACGCCAAAGGCTACATTGAGGG
GCTGGAGATGCTGGCCTCCATGCGCCTGTGCGCCAACGTGCCGATGCAGCATGCCATTCAGACTGCGCTGGGCGGATATC
AGAGCATCAGCGAGTTTATCTGCCCGGGTGGTCGGCTGTATGAACAGCGTAACCGCGCCTGGGAGCTGATCAACCAAATT
CCGGGGCTCTCCTGCGTCAAGCCGCGCGGGGCGCTGTATATGTTCCCAAAGATCGACGCCAAACGCTTTAATATTCACAA
CGATCAGAAGATGGTGCTGGATCTGCTACTGCAGGAAAAAGTCCTGCTGGTGCAGGGGACCGCCTTCAACTGGCCGGAGC
CGGATCACTTCCGCATCGTCACCCTTCCGCATGTTGACGAGCTGGACAGTGCCATCCTCAAGCTGGGGCGCTTCCTATCG
ACCTATCACCAGAAATATTGA

Upstream 100 bases:

>100_bases
CTAAACCCCGATCGCGGGGAGTACAGTATTTTATATTGCCGTGTCAGTAAGAACACCGATCCGTCAGCGGCAACGCTGAT
ATAAATAAGGCCACAGTGTT

Downstream 100 bases:

>100_bases
TCCCGTAACGGCGCCCATGGGCGCCGCTATCATTTTGACGCATAATGATGAGATCCATTACTGCGACAGGCATGACATCA
CCATGAGCCAAACCCAGAGC

Product: aminotransferase AlaT

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MSPIEKSHKLDHVCYDIRGPVLKEAKRLEEEGNKVLKLNIGNPAPFGFEAPDEILVDVIRNLPTAQGYSDSKGLYSARKA
IMQHYQAHDIRDVSVEDIYIGNGVSELIVQSMQALLNTNDEMLVPAPDYPLWTAAVALSGGNAVHYRCDEQADWFPDIDD
IRSKITPRTRGIVIINPNNPTGAVYSKALLEQIVDLAREHNLIIFADEIYDKILYDDAQHISIATLAPDLLVITFNGLSK
TYRVAGFRQGWMVLSGPKKHAKGYIEGLEMLASMRLCANVPMQHAIQTALGGYQSISEFICPGGRLYEQRNRAWELINQI
PGLSCVKPRGALYMFPKIDAKRFNIHNDQKMVLDLLLQEKVLLVQGTAFNWPEPDHFRIVTLPHVDELDSAILKLGRFLS
TYHQKY

Sequences:

>Translated_406_residues
MSPIEKSHKLDHVCYDIRGPVLKEAKRLEEEGNKVLKLNIGNPAPFGFEAPDEILVDVIRNLPTAQGYSDSKGLYSARKA
IMQHYQAHDIRDVSVEDIYIGNGVSELIVQSMQALLNTNDEMLVPAPDYPLWTAAVALSGGNAVHYRCDEQADWFPDIDD
IRSKITPRTRGIVIINPNNPTGAVYSKALLEQIVDLAREHNLIIFADEIYDKILYDDAQHISIATLAPDLLVITFNGLSK
TYRVAGFRQGWMVLSGPKKHAKGYIEGLEMLASMRLCANVPMQHAIQTALGGYQSISEFICPGGRLYEQRNRAWELINQI
PGLSCVKPRGALYMFPKIDAKRFNIHNDQKMVLDLLLQEKVLLVQGTAFNWPEPDHFRIVTLPHVDELDSAILKLGRFLS
TYHQKY
>Mature_405_residues
SPIEKSHKLDHVCYDIRGPVLKEAKRLEEEGNKVLKLNIGNPAPFGFEAPDEILVDVIRNLPTAQGYSDSKGLYSARKAI
MQHYQAHDIRDVSVEDIYIGNGVSELIVQSMQALLNTNDEMLVPAPDYPLWTAAVALSGGNAVHYRCDEQADWFPDIDDI
RSKITPRTRGIVIINPNNPTGAVYSKALLEQIVDLAREHNLIIFADEIYDKILYDDAQHISIATLAPDLLVITFNGLSKT
YRVAGFRQGWMVLSGPKKHAKGYIEGLEMLASMRLCANVPMQHAIQTALGGYQSISEFICPGGRLYEQRNRAWELINQIP
GLSCVKPRGALYMFPKIDAKRFNIHNDQKMVLDLLLQEKVLLVQGTAFNWPEPDHFRIVTLPHVDELDSAILKLGRFLST
YHQKY

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=368, Percent_Identity=26.3586956521739, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI19263340, Length=471, Percent_Identity=25.2653927813163, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI215599424, Length=379, Percent_Identity=26.9129287598945, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI4885351, Length=472, Percent_Identity=24.5762711864407, Blast_Score=118, Evalue=8e-27,
Organism=Homo sapiens, GI56713254, Length=208, Percent_Identity=26.9230769230769, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI56713256, Length=299, Percent_Identity=24.4147157190635, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI95147551, Length=175, Percent_Identity=28, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI169881279, Length=175, Percent_Identity=28, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI169881281, Length=166, Percent_Identity=28.9156626506024, Blast_Score=83, Evalue=5e-16,
Organism=Escherichia coli, GI1788627, Length=404, Percent_Identity=87.8712871287129, Blast_Score=745, Evalue=0.0,
Organism=Escherichia coli, GI1788722, Length=378, Percent_Identity=26.7195767195767, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1786816, Length=203, Percent_Identity=25.1231527093596, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787909, Length=297, Percent_Identity=23.2323232323232, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17567663, Length=369, Percent_Identity=27.9132791327913, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI71981209, Length=464, Percent_Identity=25, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71994472, Length=184, Percent_Identity=30.9782608695652, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI71994476, Length=184, Percent_Identity=30.9782608695652, Blast_Score=88, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI71981215, Length=293, Percent_Identity=25.2559726962457, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17567369, Length=242, Percent_Identity=27.2727272727273, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320317, Length=360, Percent_Identity=26.1111111111111, Blast_Score=119, Evalue=9e-28,
Organism=Saccharomyces cerevisiae, GI6323118, Length=356, Percent_Identity=27.247191011236, Blast_Score=118, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6322401, Length=205, Percent_Identity=25.8536585365854, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI18859735, Length=377, Percent_Identity=26.525198938992, Blast_Score=152, Evalue=3e-37,
Organism=Drosophila melanogaster, GI24641770, Length=471, Percent_Identity=26.7515923566879, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24641760, Length=471, Percent_Identity=26.7515923566879, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24641768, Length=471, Percent_Identity=26.7515923566879, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24641766, Length=471, Percent_Identity=26.7515923566879, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24641764, Length=471, Percent_Identity=26.7515923566879, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI45551451, Length=471, Percent_Identity=26.7515923566879, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI28573069, Length=323, Percent_Identity=25.6965944272446, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24646114, Length=323, Percent_Identity=25.6965944272446, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI28573067, Length=323, Percent_Identity=25.6965944272446, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI28573065, Length=323, Percent_Identity=25.6965944272446, Blast_Score=92, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 45705; Mature: 45574

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPIEKSHKLDHVCYDIRGPVLKEAKRLEEEGNKVLKLNIGNPAPFGFEAPDEILVDVIR
CCCCCHHCCHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLPTAQGYSDSKGLYSARKAIMQHYQAHDIRDVSVEDIYIGNGVSELIVQSMQALLNTND
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCC
EMLVPAPDYPLWTAAVALSGGNAVHYRCDEQADWFPDIDDIRSKITPRTRGIVIINPNNP
CEEEECCCCCHHHHHEEECCCCEEEEEECCCCCCCCCHHHHHHHCCCCCCEEEEECCCCC
TGAVYSKALLEQIVDLAREHNLIIFADEIYDKILYDDAQHISIATLAPDLLVITFNGLSK
CHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHCCCCCEEEEEECCCEEEEEECCCCH
TYRVAGFRQGWMVLSGPKKHAKGYIEGLEMLASMRLCANVPMQHAIQTALGGYQSISEFI
HHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHH
CPGGRLYEQRNRAWELINQIPGLSCVKPRGALYMFPKIDAKRFNIHNDQKMVLDLLLQEK
CCCHHHHHHHHHHHHHHHHCCCCCEECCCCCEEEECCCCCCEECCCCCHHHHHHHHHHCC
VLLVQGTAFNWPEPDHFRIVTLPHVDELDSAILKLGRFLSTYHQKY
EEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SPIEKSHKLDHVCYDIRGPVLKEAKRLEEEGNKVLKLNIGNPAPFGFEAPDEILVDVIR
CCCCHHCCHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLPTAQGYSDSKGLYSARKAIMQHYQAHDIRDVSVEDIYIGNGVSELIVQSMQALLNTND
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCC
EMLVPAPDYPLWTAAVALSGGNAVHYRCDEQADWFPDIDDIRSKITPRTRGIVIINPNNP
CEEEECCCCCHHHHHEEECCCCEEEEEECCCCCCCCCHHHHHHHCCCCCCEEEEECCCCC
TGAVYSKALLEQIVDLAREHNLIIFADEIYDKILYDDAQHISIATLAPDLLVITFNGLSK
CHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHCCCCCEEEEEECCCEEEEEECCCCH
TYRVAGFRQGWMVLSGPKKHAKGYIEGLEMLASMRLCANVPMQHAIQTALGGYQSISEFI
HHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHH
CPGGRLYEQRNRAWELINQIPGLSCVKPRGALYMFPKIDAKRFNIHNDQKMVLDLLLQEK
CCCHHHHHHHHHHHHHHHHCCCCCEECCCCCEEEECCCCCCEECCCCCHHHHHHHHHHCC
VLLVQGTAFNWPEPDHFRIVTLPHVDELDSAILKLGRFLSTYHQKY
EEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]