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The map label for this gene is rcsB [H]

Identifier: 238920516

GI number: 238920516

Start: 2517821

End: 2518474

Strand: Direct

Name: rcsB [H]

Synonym: NT01EI_2628

Alternate gene names: 238920516

Gene position: 2517821-2518474 (Clockwise)

Preceding gene: 238920515

Following gene: 238920519

Centisome position: 66.04

GC content: 53.98

Gene sequence:

>654_bases
ATGAATAACCTGAATGTAATCATTGCTGATGACCATCCCATTGTCCTGTTCGGCATCCGAAAGTCGCTAGAACAGATCGA
GTGGGTTAACGTGGTCGGAGAGTTTGAGGATTCCACAGCGCTGATCAATAGCCTGCCCAAACTGGACGTCAACGTACTGA
TCACCGATCTCTCCATGCCCGGTGACAAGTACGGCGACGGCATTACGCTGATCAAATACATTAAGCGCCACTTTCCCGAG
CTGTCTATCATCGTACTGACCATGAATAACAACCCGGCGATCCTCAGCGCCGTGCTGGAGCTGGATATCGAGGGGATCGT
GCTGAAACAGGGGGCGCCCACCGACCTGCCTAAGGCGCTGGCCGCCCTGCAGAAAGGTAAAAAGTTCACCCCGGAGAGCG
TCTCCAGGCTGCTGGAGAAGATCAATGCCAGCGGCTACGGCGATAAGCGCCTCTCGCCGAAAGAGAGCGAGGTTTTGCGC
CTGTTCGCCGAGGGATTTCTGGTCACCGAGATCGCCAAAAAGCTCAACCGCAGCATCAAAACCATCAGCAGCCAGAAGAA
GTCAGCAATGCTGAAGCTGGGGGTCGACAACGATATCGCCCTGCTCAACTACCTGTCATCGGTCAATATCATGCCGCATG
ATGATAAGGCATAA

Upstream 100 bases:

>100_bases
GAAGAGGCCATTAAACGCAACGATGCGGAACACGTTAACGTCCTGATCAGTCACATTGACGCTTTTGTCAGCCAACTGCT
GCAACTAGGTAACCAACAAT

Downstream 100 bases:

>100_bases
TCACAGGCCCCGCCCCCGTCGGTGAGTTTTTTTATGCCTCTTTCTCCCGGCGCCGGCGGATCTGCTGCGCATAGCCGCTG
AGGGAGGCCAGCAAATCCTC

Product: transcriptional regulator RcsB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MNNLNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINSLPKLDVNVLITDLSMPGDKYGDGITLIKYIKRHFPE
LSIIVLTMNNNPAILSAVLELDIEGIVLKQGAPTDLPKALAALQKGKKFTPESVSRLLEKINASGYGDKRLSPKESEVLR
LFAEGFLVTEIAKKLNRSIKTISSQKKSAMLKLGVDNDIALLNYLSSVNIMPHDDKA

Sequences:

>Translated_217_residues
MNNLNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINSLPKLDVNVLITDLSMPGDKYGDGITLIKYIKRHFPE
LSIIVLTMNNNPAILSAVLELDIEGIVLKQGAPTDLPKALAALQKGKKFTPESVSRLLEKINASGYGDKRLSPKESEVLR
LFAEGFLVTEIAKKLNRSIKTISSQKKSAMLKLGVDNDIALLNYLSSVNIMPHDDKA
>Mature_217_residues
MNNLNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINSLPKLDVNVLITDLSMPGDKYGDGITLIKYIKRHFPE
LSIIVLTMNNNPAILSAVLELDIEGIVLKQGAPTDLPKALAALQKGKKFTPESVSRLLEKINASGYGDKRLSPKESEVLR
LFAEGFLVTEIAKKLNRSIKTISSQKKSAMLKLGVDNDIALLNYLSSVNIMPHDDKA

Specific function: Also stimulates ftsZ expression. This suggests that rcsB is a regulator implicated in the regulation of more than one cellular function [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788546, Length=214, Percent_Identity=93.4579439252336, Blast_Score=402, Evalue=1e-114,
Organism=Escherichia coli, GI1788222, Length=204, Percent_Identity=27.4509803921569, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1790102, Length=203, Percent_Identity=30.5418719211823, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1788521, Length=200, Percent_Identity=29.5, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1786747, Length=206, Percent_Identity=27.1844660194175, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788712, Length=190, Percent_Identity=24.7368421052632, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23906; Mature: 23906

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNLNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINSLPKLDVNVLITDLSMP
CCCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCEEEEEEECCCC
GDKYGDGITLIKYIKRHFPELSIIVLTMNNNPAILSAVLELDIEGIVLKQGAPTDLPKAL
CCCCCCCHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHCCCEEEEECCCCCCHHHHH
AALQKGKKFTPESVSRLLEKINASGYGDKRLSPKESEVLRLFAEGFLVTEIAKKLNRSIK
HHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TISSQKKSAMLKLGVDNDIALLNYLSSVNIMPHDDKA
HHHHHHHHEEEEECCCCCHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNNLNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINSLPKLDVNVLITDLSMP
CCCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCEEEEEEECCCC
GDKYGDGITLIKYIKRHFPELSIIVLTMNNNPAILSAVLELDIEGIVLKQGAPTDLPKAL
CCCCCCCHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHCCCEEEEECCCCCCHHHHH
AALQKGKKFTPESVSRLLEKINASGYGDKRLSPKESEVLRLFAEGFLVTEIAKKLNRSIK
HHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TISSQKKSAMLKLGVDNDIALLNYLSSVNIMPHDDKA
HHHHHHHHEEEEECCCCCHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]