Click here to switch to the map view.

The map label for this gene is trxB [H]

Identifier: 238920376

GI number: 238920376

Start: 2380815

End: 2381786

Strand: Direct

Name: trxB [H]

Synonym: NT01EI_2486

Alternate gene names: 238920376

Gene position: 2380815-2381786 (Clockwise)

Preceding gene: 238920370

Following gene: 238920377

Centisome position: 62.45

GC content: 60.91

Gene sequence:

>972_bases
ATGAGCTCCGTAAAACATTGCAAGCTTCTCATTCTGGGCTCAGGCCCGGCGGGATATACCGCGGCCGTCTATGCAGCACG
CGCCAACCTCAATCCGGTACTGATTACCGGCATGGAAAAAGGCGGCCAGCTCACCACCACCAGTGAGTTGGAAAACTGGC
CGGGCGACCCGGAAGGGCTGACCGGTCCCCTGCTGATGGAACGCATGAATCAGCATGCGGCCAAATTCAATACCGAGATC
ATCCTTGACCATATTCAGCGCGTGGATCTCAGCCAGCGCCCGTTTCGCCTGTTTGGCGACAGCCAGGAATACAGCTGCGA
CGCGCTGATCGTCGCTACCGGCGCCTCTGCACGCTATCTGGGGCTACCGTCGGAAGAGGCCTTTAAAGGCCGCGGTGTCT
CCGCCTGCGCCACCTGTGATGGCTTTTTCTACCGTCAGCAGGAGATCGCCGTGATCGGCGGTGGCAATACCGCCGTAGAA
GAGGCTCTGTACCTGGCCAACATTGCCGCCAAGGTGCATCTGATCCACCGCCGCGACAGTTTCCGCGCCGAAAAGATCCT
TATCGACCGCCTGATGGACAAGGTGCGCAGCGGTAATATCGTCCTGCACACCAACCGTACCCTGGACGAGGTGCTCGGCG
ATGATATGGGTGTTAATGCCCTGCGGCTGAAAGATACCCAGAACGGAGCCTGCGAAGCGCTGGCCGTCAGCGGCCTGTTT
GTCGCGATCGGCCACAGCCCGAACACCGCCATCTTCGATGGCCAGCTGACGCTGAGCAACGGTTACATTCAGGTACAGTC
CGGTCTGAACGGCAACGCGACCCAGACCAGCGTCCCGGGCGTATTCGCTGCCGGCGACGTCATGGACCATATCTATCGTC
AGGCGATCACCTCTGCCGGCACCGGCTGCATGGCGGCGCTGGACGCCGAGCGCTATCTCGATAGCCTGGCCGATACCGCG
CGCCACGCCTAA

Upstream 100 bases:

>100_bases
TATTGCACAGATTGATAACATCTTTGCTGCGCGCTTTTTTTACTCCGCCAGTTTTTTTAAAATCGAATCCAAGACGCACC
ACATTGGAAAAGAGGATTTC

Downstream 100 bases:

>100_bases
TCCTTACCTATCGGGGCCGCCGCCGGCGGCCCGCATTTTACGCACGCTTCTCCTTTGGTGACAGAATTTACGGCGGCTTG
GTTTCAACTCCTCGAGCGGC

Product: thioredoxin-disulfide reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MSSVKHCKLLILGSGPAGYTAAVYAARANLNPVLITGMEKGGQLTTTSELENWPGDPEGLTGPLLMERMNQHAAKFNTEI
ILDHIQRVDLSQRPFRLFGDSQEYSCDALIVATGASARYLGLPSEEAFKGRGVSACATCDGFFYRQQEIAVIGGGNTAVE
EALYLANIAAKVHLIHRRDSFRAEKILIDRLMDKVRSGNIVLHTNRTLDEVLGDDMGVNALRLKDTQNGACEALAVSGLF
VAIGHSPNTAIFDGQLTLSNGYIQVQSGLNGNATQTSVPGVFAAGDVMDHIYRQAITSAGTGCMAALDAERYLDSLADTA
RHA

Sequences:

>Translated_323_residues
MSSVKHCKLLILGSGPAGYTAAVYAARANLNPVLITGMEKGGQLTTTSELENWPGDPEGLTGPLLMERMNQHAAKFNTEI
ILDHIQRVDLSQRPFRLFGDSQEYSCDALIVATGASARYLGLPSEEAFKGRGVSACATCDGFFYRQQEIAVIGGGNTAVE
EALYLANIAAKVHLIHRRDSFRAEKILIDRLMDKVRSGNIVLHTNRTLDEVLGDDMGVNALRLKDTQNGACEALAVSGLF
VAIGHSPNTAIFDGQLTLSNGYIQVQSGLNGNATQTSVPGVFAAGDVMDHIYRQAITSAGTGCMAALDAERYLDSLADTA
RHA
>Mature_322_residues
SSVKHCKLLILGSGPAGYTAAVYAARANLNPVLITGMEKGGQLTTTSELENWPGDPEGLTGPLLMERMNQHAAKFNTEII
LDHIQRVDLSQRPFRLFGDSQEYSCDALIVATGASARYLGLPSEEAFKGRGVSACATCDGFFYRQQEIAVIGGGNTAVEE
ALYLANIAAKVHLIHRRDSFRAEKILIDRLMDKVRSGNIVLHTNRTLDEVLGDDMGVNALRLKDTQNGACEALAVSGLFV
AIGHSPNTAIFDGQLTLSNGYIQVQSGLNGNATQTSVPGVFAAGDVMDHIYRQAITSAGTGCMAALDAERYLDSLADTAR
HA

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=319, Percent_Identity=82.4451410658307, Blast_Score=554, Evalue=1e-159,
Organism=Escherichia coli, GI87081763, Length=319, Percent_Identity=32.9153605015674, Blast_Score=129, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6320560, Length=323, Percent_Identity=49.5356037151703, Blast_Score=296, Evalue=3e-81,
Organism=Saccharomyces cerevisiae, GI6321898, Length=327, Percent_Identity=48.6238532110092, Blast_Score=296, Evalue=4e-81,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34559; Mature: 34427

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSVKHCKLLILGSGPAGYTAAVYAARANLNPVLITGMEKGGQLTTTSELENWPGDPEGL
CCCCCEEEEEEEECCCCCCEEEEEEECCCCCEEEEEECCCCCCEEEHHHHHCCCCCCCCC
TGPLLMERMNQHAAKFNTEIILDHIQRVDLSQRPFRLFGDSQEYSCDALIVATGASARYL
CHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCEEECCCCCCCCCEEEEEECCCEEEE
GLPSEEAFKGRGVSACATCDGFFYRQQEIAVIGGGNTAVEEALYLANIAAKVHLIHRRDS
CCCCHHHHCCCCCEEEEECCCCEEECEEEEEEECCCHHHHHHHHHHHHHHEEEEEECCCC
FRAEKILIDRLMDKVRSGNIVLHTNRTLDEVLGDDMGVNALRLKDTQNGACEALAVSGLF
HHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCCCCCCEEEEECCCCCCCCEEEECEEE
VAIGHSPNTAIFDGQLTLSNGYIQVQSGLNGNATQTSVPGVFAAGDVMDHIYRQAITSAG
EEECCCCCCEEEECEEEEECCEEEEECCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHCC
TGCMAALDAERYLDSLADTARHA
CCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SSVKHCKLLILGSGPAGYTAAVYAARANLNPVLITGMEKGGQLTTTSELENWPGDPEGL
CCCCEEEEEEEECCCCCCEEEEEEECCCCCEEEEEECCCCCCEEEHHHHHCCCCCCCCC
TGPLLMERMNQHAAKFNTEIILDHIQRVDLSQRPFRLFGDSQEYSCDALIVATGASARYL
CHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCEEECCCCCCCCCEEEEEECCCEEEE
GLPSEEAFKGRGVSACATCDGFFYRQQEIAVIGGGNTAVEEALYLANIAAKVHLIHRRDS
CCCCHHHHCCCCCEEEEECCCCEEECEEEEEEECCCHHHHHHHHHHHHHHEEEEEECCCC
FRAEKILIDRLMDKVRSGNIVLHTNRTLDEVLGDDMGVNALRLKDTQNGACEALAVSGLF
HHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCCCCCCEEEEECCCCCCCCEEEECEEE
VAIGHSPNTAIFDGQLTLSNGYIQVQSGLNGNATQTSVPGVFAAGDVMDHIYRQAITSAG
EEECCCCCCEEEECEEEEECCEEEEECCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHCC
TGCMAALDAERYLDSLADTARHA
CCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]