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The map label for this gene is ygfU [H]

Identifier: 238920334

GI number: 238920334

Start: 2335391

End: 2336797

Strand: Reverse

Name: ygfU [H]

Synonym: NT01EI_2444

Alternate gene names: 238920334

Gene position: 2336797-2335391 (Counterclockwise)

Preceding gene: 238920336

Following gene: 238920333

Centisome position: 61.3

GC content: 60.34

Gene sequence:

>1407_bases
ATGAGCGTCATGAAGAATCCGCCAGCGGAAAGCGCTGCGCAGCCTGTCGATGAAGTTGAGCGTAAGCTGCCTATCGCGCA
GCTGTTTACTCTGGGACTGCAGCATGTACTGGTGATGTATGCCGGCGCCGTGGCGGTGCCGCTGGTGATCGGTGGCAGCC
TTGGCCTGCCCAAAGATCAAATCGCCTTTCTGATCAGCTCCGATCTGTTTTGCTGCGGCGTAGTGACCCTGCTGCAGTGT
CTGGGGATCGGCCGCTTTGCCGGTATTCGACTGCCGGTGATCATGTCAGTTACCTTCGCTGCCGTTACGCCGATGCTGGC
GATTGGCGCCGATCCCACCATCGGCCTGACCGGGATCTTTGGCGCGACCATCGCCTCGGGGATTCTGGCGACCCTGCTGG
TACCGCTGGTCGGACGCCTGATGCCGCTGTTTCCCAACGTAGTGACCGGGGTAGTGATCACCTCTATCGGCATCAGCATT
ATGCAGGTGGGGATCGACTGGGCGGCAGGCGGCAAGGGGAATCCGGACTACGGCAGTCCGCTGTATCTGGGGACCTCGCT
GCTGGTGCTGGTGTTTATTCTGCTGGTGACCCGTTATGCCAAGGGCTTCCTCGGCAATATTTCGGTACTGCTGGGCATCG
TCTTTGGTTTCCTGGTGGCGCTGTGGCTGGGAGAGGTCAGCTTTGACGGACTGAGCGATGCTGCCTGGTTCGCGCCGATC
CACCCCTTTGCCTTTGGCTGGCCCACCTTCGAGCCAATCTCCATCGTGACGCTGACGGTGGTGATGCTGATTACCTTTAT
CGAGTCAATGGGGATGTTTCTGGCGCTGGGTGACATTGTCGGCCGCCCGGCCAAGCAGCACGATATCGTACGCGGCCTGC
GGGTGGACGGTATTGGTACCATTATCGGCGGTATGTTTAACAGCTTTCCGCACACCTCCTTTTCGCAGAACGTCGGTCTG
GTGAGCGTGACTGGGGTTGCCAGCCGCTGGGTTTGCGTGATGTCCGGCGTCATCCTGCTGATGTTCGGGCTGATCCCCAA
GATGTCGGTGATCGTGGCCTCTGTGCCGCAGTTTGTGCTGGGCGGCGCCGGGATCGTGATGTTTGGCATGGTATTGGCCA
CTGGGATCCGTATTCTGGCACGTACGGATTTCAGCCATAACCGGTTTAATCTGTATATCGTCGCCATCAGCCTGGGGGTC
GGGATGATCCCGACGGTATCCAGCCACTTCTTTAGCCAGCTTCCACCCGCCCTGCAGCCGCTGCTGCACAGCGGTATCCT
GCTGGCCAGCGTCAGCGCCGTCGCCCTGAACCTGTTCTTTAACGGCTATCAGCGCGATGAGCGGGTCGTCAAGATGCGCG
CCGAGCGGCGGGCGGCCCGTCAGGCCGACTCATCACGGGCCTCTTAG

Upstream 100 bases:

>100_bases
GGGCGCACCATCACGGCGTGCACCTGAGCCAGGGGAAGCGAATGCCTCTCGAATCGTAGCCGACGGCGGACGCCGTCGCG
CCGTAAGGAGTGATGAGTCC

Downstream 100 bases:

>100_bases
CCGCCGCAGGTGTTCAGATGCCGTAGACCGCCGCTGGGGGCTATGGCACCGTTAAATCAGCCGCGGAGCGGCGCATAGCG
GATGCGCTCGCCTGCAGAGG

Product: xanthine permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MSVMKNPPAESAAQPVDEVERKLPIAQLFTLGLQHVLVMYAGAVAVPLVIGGSLGLPKDQIAFLISSDLFCCGVVTLLQC
LGIGRFAGIRLPVIMSVTFAAVTPMLAIGADPTIGLTGIFGATIASGILATLLVPLVGRLMPLFPNVVTGVVITSIGISI
MQVGIDWAAGGKGNPDYGSPLYLGTSLLVLVFILLVTRYAKGFLGNISVLLGIVFGFLVALWLGEVSFDGLSDAAWFAPI
HPFAFGWPTFEPISIVTLTVVMLITFIESMGMFLALGDIVGRPAKQHDIVRGLRVDGIGTIIGGMFNSFPHTSFSQNVGL
VSVTGVASRWVCVMSGVILLMFGLIPKMSVIVASVPQFVLGGAGIVMFGMVLATGIRILARTDFSHNRFNLYIVAISLGV
GMIPTVSSHFFSQLPPALQPLLHSGILLASVSAVALNLFFNGYQRDERVVKMRAERRAARQADSSRAS

Sequences:

>Translated_468_residues
MSVMKNPPAESAAQPVDEVERKLPIAQLFTLGLQHVLVMYAGAVAVPLVIGGSLGLPKDQIAFLISSDLFCCGVVTLLQC
LGIGRFAGIRLPVIMSVTFAAVTPMLAIGADPTIGLTGIFGATIASGILATLLVPLVGRLMPLFPNVVTGVVITSIGISI
MQVGIDWAAGGKGNPDYGSPLYLGTSLLVLVFILLVTRYAKGFLGNISVLLGIVFGFLVALWLGEVSFDGLSDAAWFAPI
HPFAFGWPTFEPISIVTLTVVMLITFIESMGMFLALGDIVGRPAKQHDIVRGLRVDGIGTIIGGMFNSFPHTSFSQNVGL
VSVTGVASRWVCVMSGVILLMFGLIPKMSVIVASVPQFVLGGAGIVMFGMVLATGIRILARTDFSHNRFNLYIVAISLGV
GMIPTVSSHFFSQLPPALQPLLHSGILLASVSAVALNLFFNGYQRDERVVKMRAERRAARQADSSRAS
>Mature_467_residues
SVMKNPPAESAAQPVDEVERKLPIAQLFTLGLQHVLVMYAGAVAVPLVIGGSLGLPKDQIAFLISSDLFCCGVVTLLQCL
GIGRFAGIRLPVIMSVTFAAVTPMLAIGADPTIGLTGIFGATIASGILATLLVPLVGRLMPLFPNVVTGVVITSIGISIM
QVGIDWAAGGKGNPDYGSPLYLGTSLLVLVFILLVTRYAKGFLGNISVLLGIVFGFLVALWLGEVSFDGLSDAAWFAPIH
PFAFGWPTFEPISIVTLTVVMLITFIESMGMFLALGDIVGRPAKQHDIVRGLRVDGIGTIIGGMFNSFPHTSFSQNVGLV
SVTGVASRWVCVMSGVILLMFGLIPKMSVIVASVPQFVLGGAGIVMFGMVLATGIRILARTDFSHNRFNLYIVAISLGVG
MIPTVSSHFFSQLPPALQPLLHSGILLASVSAVALNLFFNGYQRDERVVKMRAERRAARQADSSRAS

Specific function: Unknown

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680143, Length=462, Percent_Identity=27.0562770562771, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI44680145, Length=458, Percent_Identity=26.8558951965066, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI44680148, Length=172, Percent_Identity=31.9767441860465, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI40316845, Length=172, Percent_Identity=31.9767441860465, Blast_Score=87, Evalue=4e-17,
Organism=Escherichia coli, GI87082181, Length=454, Percent_Identity=70.4845814977974, Blast_Score=655, Evalue=0.0,
Organism=Escherichia coli, GI1790087, Length=468, Percent_Identity=29.4871794871795, Blast_Score=165, Evalue=7e-42,
Organism=Escherichia coli, GI87082178, Length=452, Percent_Identity=28.5398230088496, Blast_Score=149, Evalue=5e-37,
Organism=Escherichia coli, GI87081818, Length=418, Percent_Identity=28.2296650717703, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1788843, Length=450, Percent_Identity=25.5555555555556, Blast_Score=110, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17558856, Length=504, Percent_Identity=24.4047619047619, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17542260, Length=240, Percent_Identity=24.5833333333333, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71993493, Length=240, Percent_Identity=24.1666666666667, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17542262, Length=188, Percent_Identity=27.6595744680851, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI21356175, Length=475, Percent_Identity=23.5789473684211, Blast_Score=98, Evalue=9e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017588
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 49487; Mature: 49356

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SVMKNPPAESAAQPVDEVERKLPIAQLFTLGLQHVLVMYAGAVAVPLVIGGSLGLPKDQ
CCCCCCCCHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH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HHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]