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The map label for this gene is lgrD [H]

Identifier: 238920283

GI number: 238920283

Start: 2288530

End: 2292249

Strand: Reverse

Name: lgrD [H]

Synonym: NT01EI_2393

Alternate gene names: 238920283

Gene position: 2292249-2288530 (Counterclockwise)

Preceding gene: 238920284

Following gene: 238920282

Centisome position: 60.13

GC content: 49.65

Gene sequence:

>3720_bases
TTGGATCACTCGGCTGATCTGGCCTGGTGGCAGCGACAACTGGAAGGGGTAACGCCTCAGCAACTTCCACTCAGGGGTAA
GCCAACAGGAAGGGCAATCACACGCAGTAAACAAATCCCTGCTGCGCTTCACCGCCAGCTCAACGAAGTCGCTATCCAAT
GCAATACAGGCCTGTTCAACATTACCTGCTCAGCACTGGCGATTCTGCTATCGCGCCTTTGCAACCAGCAGGATATTCAG
ATATCCAGTATCTGGGCAAACCGCCAGTACCCTGAAGTGGCCGAACAGATTGGTTTCTTCGTTAATACGTTGGTTATGAG
AATGCAGGTTGATCCTGAGCGCCCACTGATGCAGTGGCTGAAAAATAACCATACCCTGATTACTGAAGGATTCCGGCATG
GCGCCGCGCCTTTAAGCGATGTACTTGCCCAGAGTGGTATTCCCTCAGATGGTCATCAGCATCCCCTGTGTTCAGTACTA
TTAGTACTGCAAAATACTGAAGGTGGCGATGGTAAAGGGCTACAGCTGACAGGCTGTCACGCGCTACCTTACCCATTGCC
GGAAGAACAGGCGAAATGCGACCTGCTTTTCAATATTGTTCCTGAGCCTAATGGCGAGCTGCGCTTGGAAGCGTCCTTCC
GCGAGGGGATCTGGCCTGAAGCATTAATGAAAAGTGTGTTGGATTATTATCAGCAGATTCTGATCACTATGACGGAGCAT
CTTCACCAGTCTGTAGCCAATGCCATGGATATTGGCAATGAGATGCGTCGCCAGCAGTTACTCTCTTGGAACCCAGAAAT
TAGGGCAAAACATACGACATCGCTACTGACATTTTTTAATCAACAGGTTCAAATCCGCCCTGATGCGCCAGCCGTTTGTG
ATGTTGAAACACAATTCAGCTATCGCGAATTGAACGCGCGAGCTGATTTATTGGCCTGGCAGCTACACAAACGAGAGGGG
AGTTTATACGGTAAACGCGTGGTATTTGCACTCGATCGTAACGCAGATACCATTGCCCTGATTATTGCGATTCTGAAACA
TGGCGCAATATATGTTCCTTTCGATCCCACACATCCTGATGCCCGTCTGCTCTATATTCTGAAGGATTGCGCCTCTACCT
GTCTGATCACGGAGTCCAAATATCGACATCGGCAAACGTTCTGTCCTGAATATGACATTGCGGAGCTACTGGCTGCACCG
ATTACCGAGGCGATGCCAGGATATGCGGTATCGCAACAGGCGGATGAAGTTGCATATATCATGTATACCTCCGGTTCGAC
GGGGGAGCCTAAAGGTGTCGAAGTTCTCCATCAGGGTATCTTGCGCCTGGTTGTTGATGCAGCCCCGTACCAGGTACGCC
AAAATGCAGTGATGGCACAGACCGGGAATATTGCTTTTGATGCCTCAACCCTTGAAATCTGGGGGGCATTACTTAATGGT
GCTCACCTGATAGTCATTCCTTACCACACCGTCATCGACAGCCAGGCATTACCCGCAGCCCTGGCTAAATACCAGGTTAC
GGACGCCTGGTTTACGGTGGCGCTTTTCAATCAGCTGGCCTGTGAGGATCCCTCCTCCTTTGGTTGCCTGGAGCATCTAT
TGATCGGTGGGGATGCGTTAAACCCGGCTATCGTCGGTTCTGTGCTGGCCTCCGATGCGCCTCCGGCCCATATCTGGAAT
GGTTATGGCCCTACGGAGAATACGACTTTTACCACGCTTCATCCGATCACGATTGAGGATTGCCAGGGCGATGCCATTCC
GATCGGGCGTCCCATTGCCGGTACAATCTGTTATGTCCTCGATCAGCATCATCGCCTGTTGCCACCGGGGTTTCCCGGCG
AGCTGTACACATCAGGATTGGGGCTGGCAAAAGCCTACCTGAATAAGCCGGAAAAAACAGACGAAGCCTTTATCCCAAAT
CCCTTCTGGCACGAAAATGCTAATGGCAGCATTGCCACGCAGATGATGTATAAAACAGGTGACAAGGTGCGCTGGACAGA
ACATGGGACGCTGGGTTTTCTTGGCCGGCTGGATTATCAGATTAAAATTCGTGGATATCGTCTTGAACTGGGTGAGGTTG
AACATCGCCTGTGTGCGCTGGATATCGTGTCGCAGGCTATCGTGGATGTCCAGATGTTGCATGGTCAGAAGCAACTCGTT
GCCTGGTGCGTCAGTGAAGCATCTGCCAGCGATATACTGCGAGAATTTCGTCGGCATGTTCCCGCTTATATGGTTCCAGC
TTGTCTGGAGGTTATTGAATCCATCCCGTTAACCCCCATCGGCAAAGTAGATAAAAAACGTTTGCCACCCCCCAATATTC
ATACGGCAAGTTCGCAAAAAACACTTCCGCAGAATGACACTGAGCGTCTTTGTGCAGAAGTATGGCAGCAGTTGCTACAG
ACGGACCTTCAATACTACCGGGAGGATAATTTCTTCAATATCGGTGGCCATTCTTTGTTGGTGGTTAAAATGGCTGATTT
AATCAGCCGTAAAACCGGGAAGCAGCTCTCCGTTGCTGACGTGTTTAACTGCGAAAATCTTGCCGGGTTGGCTGCACATA
TTCAGGGTGAGAGTTTTTCTCATGATAATGAGTATCAGCAGATACTGCAGGATAGCCAGCTCGCGCTGGAGGGATTTATT
TCTACCCCTGATATTCGTCTGAACAGCCTGCTGTTAACCGGTGCGACAGGTTTTCTCGGTATTTACCTGCTGGCTACACT
ACAGCAACAATTGCCAGATGCCACAGTATATTGTCTGGGACGAGGAAAAAAAGGGATGGCGCGTTTGCGCAGCACCGCAA
AAACCTATCAGATCACGCTCGACGAACGCAGAATAAAATGGATTGAAGGTGATCTCAATCAGCCAAAACTGGGTCTTAAC
GGGCAAACATGGCAGGCATTGGCAGACAACATTGATGCTATCTATCACTGTGGTGCATGGGTAAATCACCTGCATCGCTA
TAGCACACTGCGGGCTGCAAATGTCATCAGTACGCTGGATTTACTGATGCTGTGTACATCCGGACGACAAAAACAGTTCT
TTTATGTTTCGACACTGTCTGCTGCGGCACGGCAGGATAACCGTCTGCTGGAGCAGGCCATCGCGGATACTCCAGCCATG
AATAATGGATACGTTCAAAGTAAATGGGTGTGCGAGCAACTGTTGTCACAAGCTTTTTCGAAAGGGCTACACGGCGGTAT
TTACCGTATGGGAAATATCACTGGATCAACCAGTAATGGCATATCTAACGTTGGGATCAACCATACTCTGAATCTGATTA
AAGGGTGTTTACAGCAAGGTGTTGCCCCCGAATGGCCCGGCTATCATCTTGATATCAGCCCGGTAGACCTGCTGGCGTCT
TTACTGGTTACCAGCAGTATTCATCACCCCTATCCAGACTGTGCACTTAATCTGGGACATGTGTGTGCGGTTTCCTGGAA
AAGTCTGCTGACGAGCATTGCGAAAGAGGGATATCCCTTACGTTTTGTCAGTGCTGATGAGTGGGCTACCCACTGGGTGC
CTGAAATCGGCAGTGAAAATGCGTTATATCTGTTCAAATCGTTTTATTTGACACCACGGTACTATTCCCGCGAGGAGATT
GATCACACTCTGGTTACGGATGCTGATTACAGCATCGATTTTCCGAAACTGTTGCGGCTTTATACTGATTTCTGGCTGCA
AAGTGGCTTCCTTGTGGCACCGATGGATAAGTTGGCATGA

Upstream 100 bases:

>100_bases
GGCGTTTTTTTTCCGTGAGCTTTCATCCCTCTACGCTCAGGATGACGAACTTCCTGCACTGGATTACCAATTTATCGATT
ATTGTGCCTGGCAGCAGAGG

Downstream 100 bases:

>100_bases
TGTCTAATAGCCAATATCTACCCGGAGAAAGTGAATACACTCCGGGTAACATCGGGGGGCCTCCGGGTGTTGAAGTAAAC
TCATCCGATTTTTTACATGA

Product: PsoB

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent D-leucine adenylase; D-LeuA; D-Leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent glycine adenylase; GlyA; Glycine activase; Linear gramicidin--PCP reductase [H]

Number of amino acids: Translated: 1239; Mature: 1239

Protein sequence:

>1239_residues
MDHSADLAWWQRQLEGVTPQQLPLRGKPTGRAITRSKQIPAALHRQLNEVAIQCNTGLFNITCSALAILLSRLCNQQDIQ
ISSIWANRQYPEVAEQIGFFVNTLVMRMQVDPERPLMQWLKNNHTLITEGFRHGAAPLSDVLAQSGIPSDGHQHPLCSVL
LVLQNTEGGDGKGLQLTGCHALPYPLPEEQAKCDLLFNIVPEPNGELRLEASFREGIWPEALMKSVLDYYQQILITMTEH
LHQSVANAMDIGNEMRRQQLLSWNPEIRAKHTTSLLTFFNQQVQIRPDAPAVCDVETQFSYRELNARADLLAWQLHKREG
SLYGKRVVFALDRNADTIALIIAILKHGAIYVPFDPTHPDARLLYILKDCASTCLITESKYRHRQTFCPEYDIAELLAAP
ITEAMPGYAVSQQADEVAYIMYTSGSTGEPKGVEVLHQGILRLVVDAAPYQVRQNAVMAQTGNIAFDASTLEIWGALLNG
AHLIVIPYHTVIDSQALPAALAKYQVTDAWFTVALFNQLACEDPSSFGCLEHLLIGGDALNPAIVGSVLASDAPPAHIWN
GYGPTENTTFTTLHPITIEDCQGDAIPIGRPIAGTICYVLDQHHRLLPPGFPGELYTSGLGLAKAYLNKPEKTDEAFIPN
PFWHENANGSIATQMMYKTGDKVRWTEHGTLGFLGRLDYQIKIRGYRLELGEVEHRLCALDIVSQAIVDVQMLHGQKQLV
AWCVSEASASDILREFRRHVPAYMVPACLEVIESIPLTPIGKVDKKRLPPPNIHTASSQKTLPQNDTERLCAEVWQQLLQ
TDLQYYREDNFFNIGGHSLLVVKMADLISRKTGKQLSVADVFNCENLAGLAAHIQGESFSHDNEYQQILQDSQLALEGFI
STPDIRLNSLLLTGATGFLGIYLLATLQQQLPDATVYCLGRGKKGMARLRSTAKTYQITLDERRIKWIEGDLNQPKLGLN
GQTWQALADNIDAIYHCGAWVNHLHRYSTLRAANVISTLDLLMLCTSGRQKQFFYVSTLSAAARQDNRLLEQAIADTPAM
NNGYVQSKWVCEQLLSQAFSKGLHGGIYRMGNITGSTSNGISNVGINHTLNLIKGCLQQGVAPEWPGYHLDISPVDLLAS
LLVTSSIHHPYPDCALNLGHVCAVSWKSLLTSIAKEGYPLRFVSADEWATHWVPEIGSENALYLFKSFYLTPRYYSREEI
DHTLVTDADYSIDFPKLLRLYTDFWLQSGFLVAPMDKLA

Sequences:

>Translated_1239_residues
MDHSADLAWWQRQLEGVTPQQLPLRGKPTGRAITRSKQIPAALHRQLNEVAIQCNTGLFNITCSALAILLSRLCNQQDIQ
ISSIWANRQYPEVAEQIGFFVNTLVMRMQVDPERPLMQWLKNNHTLITEGFRHGAAPLSDVLAQSGIPSDGHQHPLCSVL
LVLQNTEGGDGKGLQLTGCHALPYPLPEEQAKCDLLFNIVPEPNGELRLEASFREGIWPEALMKSVLDYYQQILITMTEH
LHQSVANAMDIGNEMRRQQLLSWNPEIRAKHTTSLLTFFNQQVQIRPDAPAVCDVETQFSYRELNARADLLAWQLHKREG
SLYGKRVVFALDRNADTIALIIAILKHGAIYVPFDPTHPDARLLYILKDCASTCLITESKYRHRQTFCPEYDIAELLAAP
ITEAMPGYAVSQQADEVAYIMYTSGSTGEPKGVEVLHQGILRLVVDAAPYQVRQNAVMAQTGNIAFDASTLEIWGALLNG
AHLIVIPYHTVIDSQALPAALAKYQVTDAWFTVALFNQLACEDPSSFGCLEHLLIGGDALNPAIVGSVLASDAPPAHIWN
GYGPTENTTFTTLHPITIEDCQGDAIPIGRPIAGTICYVLDQHHRLLPPGFPGELYTSGLGLAKAYLNKPEKTDEAFIPN
PFWHENANGSIATQMMYKTGDKVRWTEHGTLGFLGRLDYQIKIRGYRLELGEVEHRLCALDIVSQAIVDVQMLHGQKQLV
AWCVSEASASDILREFRRHVPAYMVPACLEVIESIPLTPIGKVDKKRLPPPNIHTASSQKTLPQNDTERLCAEVWQQLLQ
TDLQYYREDNFFNIGGHSLLVVKMADLISRKTGKQLSVADVFNCENLAGLAAHIQGESFSHDNEYQQILQDSQLALEGFI
STPDIRLNSLLLTGATGFLGIYLLATLQQQLPDATVYCLGRGKKGMARLRSTAKTYQITLDERRIKWIEGDLNQPKLGLN
GQTWQALADNIDAIYHCGAWVNHLHRYSTLRAANVISTLDLLMLCTSGRQKQFFYVSTLSAAARQDNRLLEQAIADTPAM
NNGYVQSKWVCEQLLSQAFSKGLHGGIYRMGNITGSTSNGISNVGINHTLNLIKGCLQQGVAPEWPGYHLDISPVDLLAS
LLVTSSIHHPYPDCALNLGHVCAVSWKSLLTSIAKEGYPLRFVSADEWATHWVPEIGSENALYLFKSFYLTPRYYSREEI
DHTLVTDADYSIDFPKLLRLYTDFWLQSGFLVAPMDKLA
>Mature_1239_residues
MDHSADLAWWQRQLEGVTPQQLPLRGKPTGRAITRSKQIPAALHRQLNEVAIQCNTGLFNITCSALAILLSRLCNQQDIQ
ISSIWANRQYPEVAEQIGFFVNTLVMRMQVDPERPLMQWLKNNHTLITEGFRHGAAPLSDVLAQSGIPSDGHQHPLCSVL
LVLQNTEGGDGKGLQLTGCHALPYPLPEEQAKCDLLFNIVPEPNGELRLEASFREGIWPEALMKSVLDYYQQILITMTEH
LHQSVANAMDIGNEMRRQQLLSWNPEIRAKHTTSLLTFFNQQVQIRPDAPAVCDVETQFSYRELNARADLLAWQLHKREG
SLYGKRVVFALDRNADTIALIIAILKHGAIYVPFDPTHPDARLLYILKDCASTCLITESKYRHRQTFCPEYDIAELLAAP
ITEAMPGYAVSQQADEVAYIMYTSGSTGEPKGVEVLHQGILRLVVDAAPYQVRQNAVMAQTGNIAFDASTLEIWGALLNG
AHLIVIPYHTVIDSQALPAALAKYQVTDAWFTVALFNQLACEDPSSFGCLEHLLIGGDALNPAIVGSVLASDAPPAHIWN
GYGPTENTTFTTLHPITIEDCQGDAIPIGRPIAGTICYVLDQHHRLLPPGFPGELYTSGLGLAKAYLNKPEKTDEAFIPN
PFWHENANGSIATQMMYKTGDKVRWTEHGTLGFLGRLDYQIKIRGYRLELGEVEHRLCALDIVSQAIVDVQMLHGQKQLV
AWCVSEASASDILREFRRHVPAYMVPACLEVIESIPLTPIGKVDKKRLPPPNIHTASSQKTLPQNDTERLCAEVWQQLLQ
TDLQYYREDNFFNIGGHSLLVVKMADLISRKTGKQLSVADVFNCENLAGLAAHIQGESFSHDNEYQQILQDSQLALEGFI
STPDIRLNSLLLTGATGFLGIYLLATLQQQLPDATVYCLGRGKKGMARLRSTAKTYQITLDERRIKWIEGDLNQPKLGLN
GQTWQALADNIDAIYHCGAWVNHLHRYSTLRAANVISTLDLLMLCTSGRQKQFFYVSTLSAAARQDNRLLEQAIADTPAM
NNGYVQSKWVCEQLLSQAFSKGLHGGIYRMGNITGSTSNGISNVGINHTLNLIKGCLQQGVAPEWPGYHLDISPVDLLAS
LLVTSSIHHPYPDCALNLGHVCAVSWKSLLTSIAKEGYPLRFVSADEWATHWVPEIGSENALYLFKSFYLTPRYYSREEI
DHTLVTDADYSIDFPKLLRLYTDFWLQSGFLVAPMDKLA

Specific function: Activates the 13th to the 16th (Trp, D-Leu, Trp and Gly) amino acids in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 14th (D-Leu) amino acid. It also catalyzes

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=567, Percent_Identity=24.8677248677249, Blast_Score=114, Evalue=6e-25,
Organism=Homo sapiens, GI38505220, Length=528, Percent_Identity=22.9166666666667, Blast_Score=87, Evalue=1e-16,
Organism=Homo sapiens, GI157311624, Length=513, Percent_Identity=23.1968810916179, Blast_Score=80, Evalue=1e-14,
Organism=Homo sapiens, GI157311622, Length=513, Percent_Identity=23.1968810916179, Blast_Score=80, Evalue=1e-14,
Organism=Homo sapiens, GI122937307, Length=540, Percent_Identity=22.7777777777778, Blast_Score=74, Evalue=9e-13,
Organism=Homo sapiens, GI195947378, Length=413, Percent_Identity=23.4866828087167, Blast_Score=69, Evalue=3e-11,
Organism=Escherichia coli, GI1786801, Length=824, Percent_Identity=29.4902912621359, Blast_Score=262, Evalue=1e-70,
Organism=Escherichia coli, GI1788107, Length=584, Percent_Identity=23.458904109589, Blast_Score=98, Evalue=3e-21,
Organism=Escherichia coli, GI1786810, Length=527, Percent_Identity=25.0474383301708, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17556356, Length=529, Percent_Identity=27.7882797731569, Blast_Score=130, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17550940, Length=873, Percent_Identity=21.8785796105384, Blast_Score=129, Evalue=9e-30,
Organism=Saccharomyces cerevisiae, GI6319591, Length=1109, Percent_Identity=26.1496844003607, Blast_Score=273, Evalue=1e-73,
Organism=Drosophila melanogaster, GI24648676, Length=627, Percent_Identity=26.9537480063796, Blast_Score=171, Evalue=4e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR013120
- InterPro:   IPR016040
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR010080 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF07993 NAD_binding_4; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 137948; Mature: 137948

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDHSADLAWWQRQLEGVTPQQLPLRGKPTGRAITRSKQIPAALHRQLNEVAIQCNTGLFN
CCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHEEEEECCCEEE
ITCSALAILLSRLCNQQDIQISSIWANRQYPEVAEQIGFFVNTLVMRMQVDPERPLMQWL
HHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
KNNHTLITEGFRHGAAPLSDVLAQSGIPSDGHQHPLCSVLLVLQNTEGGDGKGLQLTGCH
HCCCEEEECCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHEECCCCCCCCCEEEECCC
ALPYPLPEEQAKCDLLFNIVPEPNGELRLEASFREGIWPEALMKSVLDYYQQILITMTEH
CCCCCCCCCCCCCEEEEEECCCCCCCEEEEECHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LHQSVANAMDIGNEMRRQQLLSWNPEIRAKHTTSLLTFFNQQVQIRPDAPAVCDVETQFS
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEECCCCCCEECCCCCCH
YRELNARADLLAWQLHKREGSLYGKRVVFALDRNADTIALIIAILKHGAIYVPFDPTHPD
HHHHCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEECCCCCCC
ARLLYILKDCASTCLITESKYRHRQTFCPEYDIAELLAAPITEAMPGYAVSQQADEVAYI
HHHHHHHHHHHHHEEECCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHCCCCCEEEE
MYTSGSTGEPKGVEVLHQGILRLVVDAAPYQVRQNAVMAQTGNIAFDASTLEIWGALLNG
EEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCEEEEECCCEEEECHHHHHHHHHHCC
AHLIVIPYHTVIDSQALPAALAKYQVTDAWFTVALFNQLACEDPSSFGCLEHLLIGGDAL
CEEEEECCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCC
NPAIVGSVLASDAPPAHIWNGYGPTENTTFTTLHPITIEDCQGDAIPIGRPIAGTICYVL
CHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCEEEECCCCCCCCCCCCHHHHHHHHH
DQHHRLLPPGFPGELYTSGLGLAKAYLNKPEKTDEAFIPNPFWHENANGSIATQMMYKTG
HCCCCCCCCCCCHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCC
DKVRWTEHGTLGFLGRLDYQIKIRGYRLELGEVEHRLCALDIVSQAIVDVQMLHGQKQLV
CEEEEECCCCEEEEEEEEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AWCVSEASASDILREFRRHVPAYMVPACLEVIESIPLTPIGKVDKKRLPPPNIHTASSQK
HHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
TLPQNDTERLCAEVWQQLLQTDLQYYREDNFFNIGGHSLLVVKMADLISRKTGKQLSVAD
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCEEEHHHHHHHHHCCCCCEEHHH
VFNCENLAGLAAHIQGESFSHDNEYQQILQDSQLALEGFISTPDIRLNSLLLTGATGFLG
HCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEECEEEEECCHHHHH
IYLLATLQQQLPDATVYCLGRGKKGMARLRSTAKTYQITLDERRIKWIEGDLNQPKLGLN
HHHHHHHHHHCCCCEEEEECCCCHHHHHHHHCCCEEEEEECCCEEEEEECCCCCCCCCCC
GQTWQALADNIDAIYHCGAWVNHLHRYSTLRAANVISTLDLLMLCTSGRQKQFFYVSTLS
CCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHH
AAARQDNRLLEQAIADTPAMNNGYVQSKWVCEQLLSQAFSKGLHGGIYRMGNITGSTSNG
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCC
ISNVGINHTLNLIKGCLQQGVAPEWPGYHLDISPVDLLASLLVTSSIHHPYPDCALNLGH
CCCCCHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCCHHHHCCCH
VCAVSWKSLLTSIAKEGYPLRFVSADEWATHWVPEIGSENALYLFKSFYLTPRYYSREEI
HHHHHHHHHHHHHHHCCCCEEEECCCCHHHHCCCCCCCCCCEEEEHHHHCCCCCCCHHHC
DHTLVTDADYSIDFPKLLRLYTDFWLQSGFLVAPMDKLA
CCEEEECCCCCCCHHHHHHHHHHHHHHCCCEECCHHHCC
>Mature Secondary Structure
MDHSADLAWWQRQLEGVTPQQLPLRGKPTGRAITRSKQIPAALHRQLNEVAIQCNTGLFN
CCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHEEEEECCCEEE
ITCSALAILLSRLCNQQDIQISSIWANRQYPEVAEQIGFFVNTLVMRMQVDPERPLMQWL
HHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
KNNHTLITEGFRHGAAPLSDVLAQSGIPSDGHQHPLCSVLLVLQNTEGGDGKGLQLTGCH
HCCCEEEECCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHEECCCCCCCCCEEEECCC
ALPYPLPEEQAKCDLLFNIVPEPNGELRLEASFREGIWPEALMKSVLDYYQQILITMTEH
CCCCCCCCCCCCCEEEEEECCCCCCCEEEEECHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LHQSVANAMDIGNEMRRQQLLSWNPEIRAKHTTSLLTFFNQQVQIRPDAPAVCDVETQFS
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEECCCCCCEECCCCCCH
YRELNARADLLAWQLHKREGSLYGKRVVFALDRNADTIALIIAILKHGAIYVPFDPTHPD
HHHHCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEECCCCCCC
ARLLYILKDCASTCLITESKYRHRQTFCPEYDIAELLAAPITEAMPGYAVSQQADEVAYI
HHHHHHHHHHHHHEEECCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHCCCCCEEEE
MYTSGSTGEPKGVEVLHQGILRLVVDAAPYQVRQNAVMAQTGNIAFDASTLEIWGALLNG
EEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCEEEEECCCEEEECHHHHHHHHHHCC
AHLIVIPYHTVIDSQALPAALAKYQVTDAWFTVALFNQLACEDPSSFGCLEHLLIGGDAL
CEEEEECCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCC
NPAIVGSVLASDAPPAHIWNGYGPTENTTFTTLHPITIEDCQGDAIPIGRPIAGTICYVL
CHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCEEEECCCCCCCCCCCCHHHHHHHHH
DQHHRLLPPGFPGELYTSGLGLAKAYLNKPEKTDEAFIPNPFWHENANGSIATQMMYKTG
HCCCCCCCCCCCHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCC
DKVRWTEHGTLGFLGRLDYQIKIRGYRLELGEVEHRLCALDIVSQAIVDVQMLHGQKQLV
CEEEEECCCCEEEEEEEEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AWCVSEASASDILREFRRHVPAYMVPACLEVIESIPLTPIGKVDKKRLPPPNIHTASSQK
HHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
TLPQNDTERLCAEVWQQLLQTDLQYYREDNFFNIGGHSLLVVKMADLISRKTGKQLSVAD
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCEEEHHHHHHHHHCCCCCEEHHH
VFNCENLAGLAAHIQGESFSHDNEYQQILQDSQLALEGFISTPDIRLNSLLLTGATGFLG
HCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEECEEEEECCHHHHH
IYLLATLQQQLPDATVYCLGRGKKGMARLRSTAKTYQITLDERRIKWIEGDLNQPKLGLN
HHHHHHHHHHCCCCEEEEECCCCHHHHHHHHCCCEEEEEECCCEEEEEECCCCCCCCCCC
GQTWQALADNIDAIYHCGAWVNHLHRYSTLRAANVISTLDLLMLCTSGRQKQFFYVSTLS
CCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHH
AAARQDNRLLEQAIADTPAMNNGYVQSKWVCEQLLSQAFSKGLHGGIYRMGNITGSTSNG
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCC
ISNVGINHTLNLIKGCLQQGVAPEWPGYHLDISPVDLLASLLVTSSIHHPYPDCALNLGH
CCCCCHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCCHHHHCCCH
VCAVSWKSLLTSIAKEGYPLRFVSADEWATHWVPEIGSENALYLFKSFYLTPRYYSREEI
HHHHHHHHHHHHHHHCCCCEEEECCCCHHHHCCCCCCCCCCEEEEHHHHCCCCCCCHHHC
DHTLVTDADYSIDFPKLLRLYTDFWLQSGFLVAPMDKLA
CCEEEECCCCCCCHHHHHHHHHHHHHHCCCEECCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA