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The map label for this gene is fabD [H]

Identifier: 238920261

GI number: 238920261

Start: 2271435

End: 2272364

Strand: Reverse

Name: fabD [H]

Synonym: NT01EI_2370

Alternate gene names: 238920261

Gene position: 2272364-2271435 (Counterclockwise)

Preceding gene: 238920262

Following gene: 238920260

Centisome position: 59.61

GC content: 65.38

Gene sequence:

>930_bases
ATGTCTACATTTGCAATGGTATTCCCCGGGCAGGGGTCACAGACCGTGGGTATGCTGGCCGATTTAGCCGCACAGTATCC
GGTGGTCGGGCAGACCTTCGCCGAGGCCTCCGAGGCGCTGGGCTACGATCTGTGGCGCTTGGTGCAGCAGGGACCAGCCG
AAGAGCTGAACAAGACCTGGCAGACCCAGCCGGCGCTGCTGACGGCCTCCGTCGCGATTTACCGCGTCTGGCAGCAGAAC
CATGGCAAACAGCCGGCGATGATGGCCGGACACAGCCTGGGTGAGTACTCTGCGCTGGTCTGCGCCGGTGTACTCGACTT
TACGCAGGCGGTACGCCTGGTCGAGCTGCGCGGTAAGCTGATGCAGCAGGCGGTGCCGGCAGGTACCGGTGCGATGTACG
CCATCATTGGTCTGGACAACGACGCCATCGCCGCCGCCTGCACCGGGGCAGCGCAGGGGCAGGTGGTCGCGCCGGTCAAC
TTCAACTCGCCGGGGCAGGTGGTAATCGCCGGTGAAAAAGAGGCCGTCGAGCGTGCCGGGGCAGCCTGCAAGGCCGCCGG
TGCCAAGCGTGCGCTGCCGTTGCCGGTCAGCGTGCCATCCCACTGCGCGCTGATGAAGCCGGCCGCGGACCAGCTGGCCG
GGGCGCTGCAGGCCATTGCGTTTCATGCGCCGTCCTGCCCGGTGATCAATAACGTCGACGTGACGGCAGCGACCGACGCC
GATGCGATCCGCGATGCGCTGGTGCGCCAGCTCTACAGCCCGGTTCGCTGGACCGAGACCGTACAGCTGATGGCCGCCGA
AGGCGTTGACCATTTGCTGGAGATGGGCCCGGGCAAAGTGCTGACCGGTCTGACCAAGCGTATCGTCGATACCATGACCG
CCGCTGCGGTAAATGACTGCGCATCCCTGAGCGTTGCTCTCGAACAGTAA

Upstream 100 bases:

>100_bases
TCCAGCGTGGCCAGCTGATTTTGCTGGAGGCTTTCGGTGGCGGTTTCACCTGGGGCTCCGCACTGGTTCGTTTTTGATTT
TTTTGTTCAGGAAAACACTC

Downstream 100 bases:

>100_bases
GACGAGGAAAACATGAGCTTAGAAGGTAAAATTGCACTGGTAACCGGTGCCAGCCGTGGCATTGGCCGCGCTATCGCCGA
GACTCTGGCCGCCCGCGGTG

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MSTFAMVFPGQGSQTVGMLADLAAQYPVVGQTFAEASEALGYDLWRLVQQGPAEELNKTWQTQPALLTASVAIYRVWQQN
HGKQPAMMAGHSLGEYSALVCAGVLDFTQAVRLVELRGKLMQQAVPAGTGAMYAIIGLDNDAIAAACTGAAQGQVVAPVN
FNSPGQVVIAGEKEAVERAGAACKAAGAKRALPLPVSVPSHCALMKPAADQLAGALQAIAFHAPSCPVINNVDVTAATDA
DAIRDALVRQLYSPVRWTETVQLMAAEGVDHLLEMGPGKVLTGLTKRIVDTMTAAAVNDCASLSVALEQ

Sequences:

>Translated_309_residues
MSTFAMVFPGQGSQTVGMLADLAAQYPVVGQTFAEASEALGYDLWRLVQQGPAEELNKTWQTQPALLTASVAIYRVWQQN
HGKQPAMMAGHSLGEYSALVCAGVLDFTQAVRLVELRGKLMQQAVPAGTGAMYAIIGLDNDAIAAACTGAAQGQVVAPVN
FNSPGQVVIAGEKEAVERAGAACKAAGAKRALPLPVSVPSHCALMKPAADQLAGALQAIAFHAPSCPVINNVDVTAATDA
DAIRDALVRQLYSPVRWTETVQLMAAEGVDHLLEMGPGKVLTGLTKRIVDTMTAAAVNDCASLSVALEQ
>Mature_308_residues
STFAMVFPGQGSQTVGMLADLAAQYPVVGQTFAEASEALGYDLWRLVQQGPAEELNKTWQTQPALLTASVAIYRVWQQNH
GKQPAMMAGHSLGEYSALVCAGVLDFTQAVRLVELRGKLMQQAVPAGTGAMYAIIGLDNDAIAAACTGAAQGQVVAPVNF
NSPGQVVIAGEKEAVERAGAACKAAGAKRALPLPVSVPSHCALMKPAADQLAGALQAIAFHAPSCPVINNVDVTAATDAD
AIRDALVRQLYSPVRWTETVQLMAAEGVDHLLEMGPGKVLTGLTKRIVDTMTAAAVNDCASLSVALEQ

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=299, Percent_Identity=33.7792642140468, Blast_Score=147, Evalue=9e-36,
Organism=Homo sapiens, GI27477045, Length=110, Percent_Identity=42.7272727272727, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI1787334, Length=308, Percent_Identity=78.2467532467532, Blast_Score=469, Evalue=1e-133,
Organism=Caenorhabditis elegans, GI71984332, Length=296, Percent_Identity=31.7567567567568, Blast_Score=124, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI17550940, Length=298, Percent_Identity=27.8523489932886, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24665753, Length=305, Percent_Identity=34.0983606557377, Blast_Score=141, Evalue=6e-34,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32179; Mature: 32048

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTFAMVFPGQGSQTVGMLADLAAQYPVVGQTFAEASEALGYDLWRLVQQGPAEELNKTW
CCCEEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
QTQPALLTASVAIYRVWQQNHGKQPAMMAGHSLGEYSALVCAGVLDFTQAVRLVELRGKL
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MQQAVPAGTGAMYAIIGLDNDAIAAACTGAAQGQVVAPVNFNSPGQVVIAGEKEAVERAG
HHHHCCCCCCCEEEEEECCCCHHHHHCCCCCCCCEEEEECCCCCCCEEEECCHHHHHHHC
AACKAAGAKRALPLPVSVPSHCALMKPAADQLAGALQAIAFHAPSCPVINNVDVTAATDA
CHHHHCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCH
DAIRDALVRQLYSPVRWTETVQLMAAEGVDHLLEMGPGKVLTGLTKRIVDTMTAAAVNDC
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ASLSVALEQ
HHHEEEECC
>Mature Secondary Structure 
STFAMVFPGQGSQTVGMLADLAAQYPVVGQTFAEASEALGYDLWRLVQQGPAEELNKTW
CCEEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
QTQPALLTASVAIYRVWQQNHGKQPAMMAGHSLGEYSALVCAGVLDFTQAVRLVELRGKL
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MQQAVPAGTGAMYAIIGLDNDAIAAACTGAAQGQVVAPVNFNSPGQVVIAGEKEAVERAG
HHHHCCCCCCCEEEEEECCCCHHHHHCCCCCCCCEEEEECCCCCCCEEEECCHHHHHHHC
AACKAAGAKRALPLPVSVPSHCALMKPAADQLAGALQAIAFHAPSCPVINNVDVTAATDA
CHHHHCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCH
DAIRDALVRQLYSPVRWTETVQLMAAEGVDHLLEMGPGKVLTGLTKRIVDTMTAAAVNDC
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ASLSVALEQ
HHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]