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The map label for this gene is ndh [H]

Identifier: 238920226

GI number: 238920226

Start: 2236238

End: 2237542

Strand: Reverse

Name: ndh [H]

Synonym: NT01EI_2335

Alternate gene names: 238920226

Gene position: 2237542-2236238 (Counterclockwise)

Preceding gene: 238920227

Following gene: 238920225

Centisome position: 58.69

GC content: 62.07

Gene sequence:

>1305_bases
TTGAGCGCAGCAAAGAAGAAAATCGTGATTGTTGGCGGTGGCGCCGGCGGACTCGAACTGGCAACCAGCCTGGGACATTC
GCTGGGGCGCAAGGGTAAGGCAGAGATCGTGCTTATCGATCGCAACCACAGCCACCTGTGGAAGCCGCTGCTGCATGAAG
TGGCGACGGGATCGCTGGATGACGGTGTCGATGCCCTGAGCTATCTGGCCCATGCGCGCAACCACCACTTCACCTTTCAG
CTGGGCAGCATGACGGTGCTCGATCGTCACTCCCGCCGGGTCACGCTGGCGGAGATCCGCGATGAGCAGGATACGCTGCT
GGTTGCCGAGCGTCAGCTGGACTACGACATTCTGGTGATGGCCCTGGGCAGCACCTCAAACGATTTCGGCACGCCGGGCG
TGAGTCAGAACTGCATATTTCTGGACAGCCCGCAGCAGGCGCACCGTTTCCATAACGAAATGCTGAACCTGTTCCTGAAG
TACTCGGCGGCGGGAAAAACGGACGATCAGGTAAATATCGCCATCGTCGGCGGCGGGGCCACCGGCGTCGAGCTGTCCGC
AGAGCTGCACAACGCGGTGAAGCAGCTGCAGAGCTACGGCTATGAAAATCTTAGCAGTGCCGCGCTGAACGTGACGCTGG
TGGAGGCAGGGGAGCGCATTCTGCCGGCGCTGCCGCCGCGTATCTCCGGCGCGGCCCACCAGGAGCTGAGCAATCTGGGG
GTGCGGGTCCTGACCAACACCCTGGTGACCCACGCCGGGGCCAACGGCCTGCAGACCAAAGAGGGCGGGTTTATCCCGGC
CGATCTGATGGTGTGGGCGGCAGGGATCAAGGCGCCGGACTTCCTGCGCGATATCGGCGGCCTGGAGACCAACCGAATCA
ACCAGCTGGTGGTGAAGCCGACGCTGCAGACCACCCTGGATAGTCATATCTTCGCCATCGGCGACTGCGCGGCCTGCGCG
CAGCCGGACGGGCGCAATGTGCCACCGCGCGGCCAGGCCGCCCACCAGATGGCGACGCTGTGCGCCGCCAATATTCTGGC
ACTGCTGAAGGCGGCGCCGCTGAAGGATTATCTCTATCACGATCGCGGATCGCTGGTCTCCCTGTCGAAGTTCAGTACCG
TAGGCAGCCTGATGGGGAATCTGACGCGGGGATCGATGATGATCGAAGGGCGTATCGCGCGTATCATGTATATCTCGCTG
TACCGCATGCACCAGATTGCGCTGCACGGCTGTATCAAGACCGGTCTGATGATGCTGGTCGATAGCATCAACCGGGTGAT
CCGTCCGCACCTGAAGTTGCACTGA

Upstream 100 bases:

>100_bases
GAACGACAGTAACCTTCGTCAGCCAAGCGGCCACTCTGGGTCATGTGGAGGCCATCTTTGGTTAACGAATGGTTTGCATT
TTTTACCAAGGGAGAAAGCT

Downstream 100 bases:

>100_bases
TCGCATCGCGGGCCGACGGGCGCCGCCGCGGGCCCGTCGCGTTTCCCCCTCTTGACCCAGCCCGGTGCGGCGCGCACACT
GGACAGCCCATGAACACCGC

Product: NADH dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 433

Protein sequence:

>434_residues
MSAAKKKIVIVGGGAGGLELATSLGHSLGRKGKAEIVLIDRNHSHLWKPLLHEVATGSLDDGVDALSYLAHARNHHFTFQ
LGSMTVLDRHSRRVTLAEIRDEQDTLLVAERQLDYDILVMALGSTSNDFGTPGVSQNCIFLDSPQQAHRFHNEMLNLFLK
YSAAGKTDDQVNIAIVGGGATGVELSAELHNAVKQLQSYGYENLSSAALNVTLVEAGERILPALPPRISGAAHQELSNLG
VRVLTNTLVTHAGANGLQTKEGGFIPADLMVWAAGIKAPDFLRDIGGLETNRINQLVVKPTLQTTLDSHIFAIGDCAACA
QPDGRNVPPRGQAAHQMATLCAANILALLKAAPLKDYLYHDRGSLVSLSKFSTVGSLMGNLTRGSMMIEGRIARIMYISL
YRMHQIALHGCIKTGLMMLVDSINRVIRPHLKLH

Sequences:

>Translated_434_residues
MSAAKKKIVIVGGGAGGLELATSLGHSLGRKGKAEIVLIDRNHSHLWKPLLHEVATGSLDDGVDALSYLAHARNHHFTFQ
LGSMTVLDRHSRRVTLAEIRDEQDTLLVAERQLDYDILVMALGSTSNDFGTPGVSQNCIFLDSPQQAHRFHNEMLNLFLK
YSAAGKTDDQVNIAIVGGGATGVELSAELHNAVKQLQSYGYENLSSAALNVTLVEAGERILPALPPRISGAAHQELSNLG
VRVLTNTLVTHAGANGLQTKEGGFIPADLMVWAAGIKAPDFLRDIGGLETNRINQLVVKPTLQTTLDSHIFAIGDCAACA
QPDGRNVPPRGQAAHQMATLCAANILALLKAAPLKDYLYHDRGSLVSLSKFSTVGSLMGNLTRGSMMIEGRIARIMYISL
YRMHQIALHGCIKTGLMMLVDSINRVIRPHLKLH
>Mature_433_residues
SAAKKKIVIVGGGAGGLELATSLGHSLGRKGKAEIVLIDRNHSHLWKPLLHEVATGSLDDGVDALSYLAHARNHHFTFQL
GSMTVLDRHSRRVTLAEIRDEQDTLLVAERQLDYDILVMALGSTSNDFGTPGVSQNCIFLDSPQQAHRFHNEMLNLFLKY
SAAGKTDDQVNIAIVGGGATGVELSAELHNAVKQLQSYGYENLSSAALNVTLVEAGERILPALPPRISGAAHQELSNLGV
RVLTNTLVTHAGANGLQTKEGGFIPADLMVWAAGIKAPDFLRDIGGLETNRINQLVVKPTLQTTLDSHIFAIGDCAACAQ
PDGRNVPPRGQAAHQMATLCAANILALLKAAPLKDYLYHDRGSLVSLSKFSTVGSLMGNLTRGSMMIEGRIARIMYISLY
RMHQIALHGCIKTGLMMLVDSINRVIRPHLKLH

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787352, Length=434, Percent_Identity=76.7281105990783, Blast_Score=665, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323794, Length=355, Percent_Identity=26.4788732394366, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323515, Length=448, Percent_Identity=25, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6320118, Length=345, Percent_Identity=25.2173913043478, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 46797; Mature: 46665

Theoretical pI: Translated: 8.27; Mature: 8.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAAKKKIVIVGGGAGGLELATSLGHSLGRKGKAEIVLIDRNHSHLWKPLLHEVATGSLD
CCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCC
DGVDALSYLAHARNHHFTFQLGSMTVLDRHSRRVTLAEIRDEQDTLLVAERQLDYDILVM
CHHHHHHHHHHHCCCEEEEEECCEEEEECCCCEEEHHHHCCCCCEEEEEHHCCCCEEEEE
ALGSTSNDFGTPGVSQNCIFLDSPQQAHRFHNEMLNLFLKYSAAGKTDDQVNIAIVGGGA
EECCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCC
TGVELSAELHNAVKQLQSYGYENLSSAALNVTLVEAGERILPALPPRISGAAHQELSNLG
CCEEEHHHHHHHHHHHHHCCCCCCCCHHEEEEEECCCCHHCCCCCCCCCCHHHHHHHHCC
VRVLTNTLVTHAGANGLQTKEGGFIPADLMVWAAGIKAPDFLRDIGGLETNRINQLVVKP
HHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEECC
TLQTTLDSHIFAIGDCAACAQPDGRNVPPRGQAAHQMATLCAANILALLKAAPLKDYLYH
HHHHHHHCCEEEEECHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCC
DRGSLVSLSKFSTVGSLMGNLTRGSMMIEGRIARIMYISLYRMHQIALHGCIKTGLMMLV
CCCCEEEHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DSINRVIRPHLKLH
HHHHHHHCCCCCCC
>Mature Secondary Structure 
SAAKKKIVIVGGGAGGLELATSLGHSLGRKGKAEIVLIDRNHSHLWKPLLHEVATGSLD
CCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCC
DGVDALSYLAHARNHHFTFQLGSMTVLDRHSRRVTLAEIRDEQDTLLVAERQLDYDILVM
CHHHHHHHHHHHCCCEEEEEECCEEEEECCCCEEEHHHHCCCCCEEEEEHHCCCCEEEEE
ALGSTSNDFGTPGVSQNCIFLDSPQQAHRFHNEMLNLFLKYSAAGKTDDQVNIAIVGGGA
EECCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCC
TGVELSAELHNAVKQLQSYGYENLSSAALNVTLVEAGERILPALPPRISGAAHQELSNLG
CCEEEHHHHHHHHHHHHHCCCCCCCCHHEEEEEECCCCHHCCCCCCCCCCHHHHHHHHCC
VRVLTNTLVTHAGANGLQTKEGGFIPADLMVWAAGIKAPDFLRDIGGLETNRINQLVVKP
HHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEECC
TLQTTLDSHIFAIGDCAACAQPDGRNVPPRGQAAHQMATLCAANILALLKAAPLKDYLYH
HHHHHHHCCEEEEECHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCC
DRGSLVSLSKFSTVGSLMGNLTRGSMMIEGRIARIMYISLYRMHQIALHGCIKTGLMMLV
CCCCEEEHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DSINRVIRPHLKLH
HHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6265208; 8905232; 9278503 [H]