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The map label for this gene is cbiA [H]

Identifier: 238920088

GI number: 238920088

Start: 2117098

End: 2118477

Strand: Reverse

Name: cbiA [H]

Synonym: NT01EI_2193

Alternate gene names: 238920088

Gene position: 2118477-2117098 (Counterclockwise)

Preceding gene: 238920091

Following gene: 238920087

Centisome position: 55.57

GC content: 65.94

Gene sequence:

>1380_bases
ATGACGGCAAAGCAGTACGCGTTCGTTCTGGCGGGCACCGGCAGCGGCTGTGGCAAAACCACGCTGACGCTGGGGTTGCT
GAGTCTATTGAAACAGCGTGGGCTGCGCGTCCAGCCGTACAAAGTGGGGCCGGACTACCTCGATACTGCCTGGCATACGG
CCGTGTGCGGCACCGCCTCCTGCAATCTCGATAGTTTTATGCTGCCCGAACCGACGCTCAACGCGCTGTTTGGCGAGCGG
ATGCAGCAGGCCGACATCGCGGTCATCGAGGGGGTGATGGGGCTGTATGACGGCTACGGCACCGATCCGGACTACTGCAG
CAGCGCGGGGATGGCCAAGCAGCTCGGCTGCCCGGTGATCCTGCTGGTGGATGGCAAGGCGGTCTCCACTTCTATTGCCG
CCACGGTGATGGGCTTTCAGCGCTTTGATCCCACCTTGAATATCGCGGGCGTGATGGTGAATCGCGTCAACAGCGAGGCG
CATTTCGCGCTGCTTAAGACGGCCATCGAACGCTACTGCGCCATTCCCGTGCTCGGCTATATCCCACAGACGGCGGGGGT
TGCCCTGCCTGAGCGCCACCTCGGCCTGGTGACCGCCCGGGAGTCCGTCGTGCGGGCGCAGCCCTGGCAGACGTTTGCCG
CCGTACTCGAACGCACCCTGGATATCGATCGCTTGCTCTTTTTGTGCCAGATGGCGTCGCTGCCGCCCGGCGCCTGGCCT
GCGCTGCCCACCGCCGACGCCGGACGCGGATTGACGCTGGCCATGGCCGAGGACGAGGCGTTCAACTTCTATTATCCGGA
CAACGTTGCGCTGCTCGAGCGCACGGGCGTTAGGATCGTCCGCTTTAGCCCCCTGCATGACGCCCGGCTGCCCGACTGCC
AGATGGTGTGGCTGGGCGGCGGCTACCCGGAGCTGTACGCCGGGAGGCTGGCGGCCAACGCCCCGATGCTGGCGAGCCTG
CGCGCGGCGCACCGGCGCGGCGCGGCGATCTACGCCGAGTGCGGCGGGCTGATGTACCTTGGCAGCACGCTGGAGGATGC
CGACGGCGAGATCCACCCCATGGCCAATATTATTCCCGGTCACAGTAAAATGGGGCGGCGGCTGACCCGCTTTGGCTACT
GTGAGGCACAGGCGCGTCAGCCGACGCTGCTGGCGGATCGCGGCGAAACGCTGCGCGGACACGAGTTCCACTACGCTGAC
TTTTCACCGCAAACCCCCGCGCTGCTGGCGTGCCGCAAAGTGCGCGATGGGGTGACCACCCAGACGTGGGACGGGGGATG
GCAGGTCGGCAGCGCCTTTGCCAGCTATCTGCACCTGCATTTTGCCCAGCGCCCACAGATGCTGAACCGCTGGCTGGCGG
CCGCCAGGGCGGCCCTATGA

Upstream 100 bases:

>100_bases
AACAACTTCGGTGGGAAGTGGGTTGATCTGATGCATACAGTCGCAAGACTGGGTAGCGGTGTATCTATACCCTCCAACCA
CCCTGAACAGGATCAGGGGC

Downstream 100 bases:

>100_bases
CGCTCCTGGCCTGGTGTCTCGCCTGGATCCTCGACGCCGCGATCGGCGATCCGCCGCGCTGGCCGCACCCGGTACGCTGG
ATGGGGCAGCTGATCACCGC

Product: cobyrinic acid a,c-diamide synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 458

Protein sequence:

>459_residues
MTAKQYAFVLAGTGSGCGKTTLTLGLLSLLKQRGLRVQPYKVGPDYLDTAWHTAVCGTASCNLDSFMLPEPTLNALFGER
MQQADIAVIEGVMGLYDGYGTDPDYCSSAGMAKQLGCPVILLVDGKAVSTSIAATVMGFQRFDPTLNIAGVMVNRVNSEA
HFALLKTAIERYCAIPVLGYIPQTAGVALPERHLGLVTARESVVRAQPWQTFAAVLERTLDIDRLLFLCQMASLPPGAWP
ALPTADAGRGLTLAMAEDEAFNFYYPDNVALLERTGVRIVRFSPLHDARLPDCQMVWLGGGYPELYAGRLAANAPMLASL
RAAHRRGAAIYAECGGLMYLGSTLEDADGEIHPMANIIPGHSKMGRRLTRFGYCEAQARQPTLLADRGETLRGHEFHYAD
FSPQTPALLACRKVRDGVTTQTWDGGWQVGSAFASYLHLHFAQRPQMLNRWLAAARAAL

Sequences:

>Translated_459_residues
MTAKQYAFVLAGTGSGCGKTTLTLGLLSLLKQRGLRVQPYKVGPDYLDTAWHTAVCGTASCNLDSFMLPEPTLNALFGER
MQQADIAVIEGVMGLYDGYGTDPDYCSSAGMAKQLGCPVILLVDGKAVSTSIAATVMGFQRFDPTLNIAGVMVNRVNSEA
HFALLKTAIERYCAIPVLGYIPQTAGVALPERHLGLVTARESVVRAQPWQTFAAVLERTLDIDRLLFLCQMASLPPGAWP
ALPTADAGRGLTLAMAEDEAFNFYYPDNVALLERTGVRIVRFSPLHDARLPDCQMVWLGGGYPELYAGRLAANAPMLASL
RAAHRRGAAIYAECGGLMYLGSTLEDADGEIHPMANIIPGHSKMGRRLTRFGYCEAQARQPTLLADRGETLRGHEFHYAD
FSPQTPALLACRKVRDGVTTQTWDGGWQVGSAFASYLHLHFAQRPQMLNRWLAAARAAL
>Mature_458_residues
TAKQYAFVLAGTGSGCGKTTLTLGLLSLLKQRGLRVQPYKVGPDYLDTAWHTAVCGTASCNLDSFMLPEPTLNALFGERM
QQADIAVIEGVMGLYDGYGTDPDYCSSAGMAKQLGCPVILLVDGKAVSTSIAATVMGFQRFDPTLNIAGVMVNRVNSEAH
FALLKTAIERYCAIPVLGYIPQTAGVALPERHLGLVTARESVVRAQPWQTFAAVLERTLDIDRLLFLCQMASLPPGAWPA
LPTADAGRGLTLAMAEDEAFNFYYPDNVALLERTGVRIVRFSPLHDARLPDCQMVWLGGGYPELYAGRLAANAPMLASLR
AAHRRGAAIYAECGGLMYLGSTLEDADGEIHPMANIIPGHSKMGRRLTRFGYCEAQARQPTLLADRGETLRGHEFHYADF
SPQTPALLACRKVRDGVTTQTWDGGWQVGSAFASYLHLHFAQRPQMLNRWLAAARAAL

Specific function: Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation [H]

COG id: COG1797

COG function: function code H; Cobyrinic acid a,c-diamide synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR004484
- InterPro:   IPR017929
- InterPro:   IPR011698 [H]

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]

EC number: NA

Molecular weight: Translated: 49801; Mature: 49670

Theoretical pI: Translated: 7.48; Mature: 7.48

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAKQYAFVLAGTGSGCGKTTLTLGLLSLLKQRGLRVQPYKVGPDYLDTAWHTAVCGTAS
CCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCCC
CNLDSFMLPEPTLNALFGERMQQADIAVIEGVMGLYDGYGTDPDYCSSAGMAKQLGCPVI
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHCCCCEE
LLVDGKAVSTSIAATVMGFQRFDPTLNIAGVMVNRVNSEAHFALLKTAIERYCAIPVLGY
EEECCCHHHHHHHHHHHHHHHCCCCCEEHHHEEECCCCHHHHHHHHHHHHHHHHCCHHHC
IPQTAGVALPERHLGLVTARESVVRAQPWQTFAAVLERTLDIDRLLFLCQMASLPPGAWP
CCCCCCCCCCHHHCCCHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCC
ALPTADAGRGLTLAMAEDEAFNFYYPDNVALLERTGVRIVRFSPLHDARLPDCQMVWLGG
CCCCCCCCCCEEEEEECCCCEEEECCCCEEEEECCCEEEEEECCCCCCCCCCCEEEEECC
GYPELYAGRLAANAPMLASLRAAHRRGAAIYAECGGLMYLGSTLEDADGEIHPMANIIPG
CCHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCEEEECCCCCCCCCCCCCHHHCCCC
HSKMGRRLTRFGYCEAQARQPTLLADRGETLRGHEFHYADFSPQTPALLACRKVRDGVTT
HHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCC
QTWDGGWQVGSAFASYLHLHFAQRPQMLNRWLAAARAAL
CCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TAKQYAFVLAGTGSGCGKTTLTLGLLSLLKQRGLRVQPYKVGPDYLDTAWHTAVCGTAS
CCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCCC
CNLDSFMLPEPTLNALFGERMQQADIAVIEGVMGLYDGYGTDPDYCSSAGMAKQLGCPVI
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHCCCCEE
LLVDGKAVSTSIAATVMGFQRFDPTLNIAGVMVNRVNSEAHFALLKTAIERYCAIPVLGY
EEECCCHHHHHHHHHHHHHHHCCCCCEEHHHEEECCCCHHHHHHHHHHHHHHHHCCHHHC
IPQTAGVALPERHLGLVTARESVVRAQPWQTFAAVLERTLDIDRLLFLCQMASLPPGAWP
CCCCCCCCCCHHHCCCHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCC
ALPTADAGRGLTLAMAEDEAFNFYYPDNVALLERTGVRIVRFSPLHDARLPDCQMVWLGG
CCCCCCCCCCEEEEEECCCCEEEECCCCEEEEECCCEEEEEECCCCCCCCCCCEEEEECC
GYPELYAGRLAANAPMLASLRAAHRRGAAIYAECGGLMYLGSTLEDADGEIHPMANIIPG
CCHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCEEEECCCCCCCCCCCCCHHHCCCC
HSKMGRRLTRFGYCEAQARQPTLLADRGETLRGHEFHYADFSPQTPALLACRKVRDGVTT
HHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCC
QTWDGGWQVGSAFASYLHLHFAQRPQMLNRWLAAARAAL
CCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8501034; 11677609; 1374146 [H]