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The map label for this gene is cbiP [H]

Identifier: 238920075

GI number: 238920075

Start: 2106590

End: 2108119

Strand: Reverse

Name: cbiP [H]

Synonym: NT01EI_2180

Alternate gene names: 238920075

Gene position: 2108119-2106590 (Counterclockwise)

Preceding gene: 238920076

Following gene: 238920074

Centisome position: 55.3

GC content: 62.94

Gene sequence:

>1530_bases
ATGACGCAGGCGATGGCGATTATGCTGCAGGGAACCGCTTCTGACGTGGGTAAAAGCGTGCTGGTGGCGGGGCTGTGCCG
CATTTTTTATCAGGACGGTCTGCGCACGGCGCCCTTTAAGTCACAGAATATGGCGCTGAATTCCGGTATCACGCCGGATG
GCAAAGAGATGGGGCGCGCCCAGATTTTTCAGGCGCAGGCGGCGGGCATCGCGCCGGACGTGCGGATGAACCCGGTGTTG
CTCAAGCCGACCAGCGACCGCAAAGCACAGGTGGTGCTGATGGGGGAGGTGGCGACCGACATGGACGCCGTCAGCTACCA
CCAGTACAAGCCGCGTCTGCGTGAGCGCATTCTGGCGGTCTACCGGAGTCTGGCGCAGCAGTATCAGGTGCTGGTGCTGG
AGGGGGCCGGCAGTCCGGCGGAGATAAACCTACGCGATCGCGATATCGTCAACATGGGGATGGCCGAGATGGCGCGCTGC
CCGGTGATCCTGGTGGCAGATATCGACAAAGGGGGCGTCTTCGCCTCTATCTATGGCACGCTGGCACTGCTGCGTCAGGG
CGAGCGGAGCCGGGTCAAAGGGGTAATTATCAATAAATTTCGCGGCGATGTGGCGCTGCTGCACTCCGGCATTGAACAGA
TTGAGGCGCTGACGGGGGTGCCGGTGCTGGGCGTGATGCCGTGGCTCGATCTGGATCTCGACGATGAGGATGGCGTCGCG
CTGCAGAAGGGCAAATACCGGCAGACGGCGCCGCGTGATCTCGATATCGCCGTGGTGCAGCTGCCGCATATCTCTAACTT
CACCGATTTTAACGCCCTGGCGGCGCAGCCGGATGTCAGGGTGCGCTATGTCAGCCATCCGCAGGCGCTGGCCGACGCCG
ATCTGGTGATTTTGCCGGGCAGTAAAAATACGCTGGGCGATCTGGGCTGGCTGCGTGAAAGCGGCATCGCCGCTGCGCTG
CTGCAGGCGCACCGGCAGCGGGTGCCGGTGATGGGGATCTGTGGCGGTTACCAGATGCTGGGCCGCACCATTATCGACGA
GGTGGAATCGGGGCTGGGGACGCAGCCGGGCCTTGGCCTGCTGAATATCGTCACCCGCTTCGCGCCGCGGAAAACCACCG
TGCAGAGCGCGGCACAGGTGACGATGACGCCGCCGGGGTGGCTGCACGCCGCCGCCGGTGTCGCGGTGAAAGGCTATGAG
ATCCACATGGGGGAAACGCAGCGGGCGGCCGACTGCCGCCCGGCGCTGTTTATCGGGCGAGACGGCGGGCGGGTGGCGGA
TGGCGCCATCAGCGACGATGGGCTGGTGTTCGGCACCTACCTGCATGGACTGTTCGACAGCGACGCCTTTACGCACGCCG
TGCTGGACAGCCTGCGTCATCGCAAGGGGCTGGCGCCGCTGGAAAGGACCCTGGACTATGCGGCCTACAAAGCCCAACAG
ATCGATCTTCTGGCCAGTGCAATGAGAGAGCATATTGATATTAAAGAAATTTATAAAATAATGCGCGGGCATCGGGAGGC
GGAGGCATGA

Upstream 100 bases:

>100_bases
TGACCTCCGTTGTGACCCCGTCAGCGCTGGGGCTGGCGCGCTATAAGCGTGAAGAGAAGTTTTTCCGGCGTATGCGATAC
AACGCGATAAAGGAGGCCCG

Downstream 100 bases:

>100_bases
TTTTGGTTACCGGAGGGGCGCGCAGCGGAAAGAGCGCGCATGTCGAGCGGCTGGCAGCTCAGCGCTGCGCGCGCATTCTG
TATATTGCGACCTCCACCGT

Product: cobyric acid synthase

Products: ADP; phosphate; adenosylcobyric acid; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 509; Mature: 508

Protein sequence:

>509_residues
MTQAMAIMLQGTASDVGKSVLVAGLCRIFYQDGLRTAPFKSQNMALNSGITPDGKEMGRAQIFQAQAAGIAPDVRMNPVL
LKPTSDRKAQVVLMGEVATDMDAVSYHQYKPRLRERILAVYRSLAQQYQVLVLEGAGSPAEINLRDRDIVNMGMAEMARC
PVILVADIDKGGVFASIYGTLALLRQGERSRVKGVIINKFRGDVALLHSGIEQIEALTGVPVLGVMPWLDLDLDDEDGVA
LQKGKYRQTAPRDLDIAVVQLPHISNFTDFNALAAQPDVRVRYVSHPQALADADLVILPGSKNTLGDLGWLRESGIAAAL
LQAHRQRVPVMGICGGYQMLGRTIIDEVESGLGTQPGLGLLNIVTRFAPRKTTVQSAAQVTMTPPGWLHAAAGVAVKGYE
IHMGETQRAADCRPALFIGRDGGRVADGAISDDGLVFGTYLHGLFDSDAFTHAVLDSLRHRKGLAPLERTLDYAAYKAQQ
IDLLASAMREHIDIKEIYKIMRGHREAEA

Sequences:

>Translated_509_residues
MTQAMAIMLQGTASDVGKSVLVAGLCRIFYQDGLRTAPFKSQNMALNSGITPDGKEMGRAQIFQAQAAGIAPDVRMNPVL
LKPTSDRKAQVVLMGEVATDMDAVSYHQYKPRLRERILAVYRSLAQQYQVLVLEGAGSPAEINLRDRDIVNMGMAEMARC
PVILVADIDKGGVFASIYGTLALLRQGERSRVKGVIINKFRGDVALLHSGIEQIEALTGVPVLGVMPWLDLDLDDEDGVA
LQKGKYRQTAPRDLDIAVVQLPHISNFTDFNALAAQPDVRVRYVSHPQALADADLVILPGSKNTLGDLGWLRESGIAAAL
LQAHRQRVPVMGICGGYQMLGRTIIDEVESGLGTQPGLGLLNIVTRFAPRKTTVQSAAQVTMTPPGWLHAAAGVAVKGYE
IHMGETQRAADCRPALFIGRDGGRVADGAISDDGLVFGTYLHGLFDSDAFTHAVLDSLRHRKGLAPLERTLDYAAYKAQQ
IDLLASAMREHIDIKEIYKIMRGHREAEA
>Mature_508_residues
TQAMAIMLQGTASDVGKSVLVAGLCRIFYQDGLRTAPFKSQNMALNSGITPDGKEMGRAQIFQAQAAGIAPDVRMNPVLL
KPTSDRKAQVVLMGEVATDMDAVSYHQYKPRLRERILAVYRSLAQQYQVLVLEGAGSPAEINLRDRDIVNMGMAEMARCP
VILVADIDKGGVFASIYGTLALLRQGERSRVKGVIINKFRGDVALLHSGIEQIEALTGVPVLGVMPWLDLDLDDEDGVAL
QKGKYRQTAPRDLDIAVVQLPHISNFTDFNALAAQPDVRVRYVSHPQALADADLVILPGSKNTLGDLGWLRESGIAAALL
QAHRQRVPVMGICGGYQMLGRTIIDEVESGLGTQPGLGLLNIVTRFAPRKTTVQSAAQVTMTPPGWLHAAAGVAVKGYEI
HMGETQRAADCRPALFIGRDGGRVADGAISDDGLVFGTYLHGLFDSDAFTHAVLDSLRHRKGLAPLERTLDYAAYKAQQI
DLLASAMREHIDIKEIYKIMRGHREAEA

Specific function: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation [H]

COG id: COG1492

COG function: function code H; Cobyric acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR017929
- InterPro:   IPR004459
- InterPro:   IPR011698 [H]

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]

EC number: 6.3.5.10

Molecular weight: Translated: 55208; Mature: 55077

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQAMAIMLQGTASDVGKSVLVAGLCRIFYQDGLRTAPFKSQNMALNSGITPDGKEMGRA
CCCEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCHHHHCHH
QIFQAQAAGIAPDVRMNPVLLKPTSDRKAQVVLMGEVATDMDAVSYHQYKPRLRERILAV
HHHHHHHCCCCCCCCCCCEEECCCCCCCEEEEEEECHHCCHHHHHHHHHHHHHHHHHHHH
YRSLAQQYQVLVLEGAGSPAEINLRDRDIVNMGMAEMARCPVILVADIDKGGVFASIYGT
HHHHHHCEEEEEEECCCCCCEEEECCCHHHHCCHHHHHCCCEEEEEECCCCCCHHHHHHH
LALLRQGERSRVKGVIINKFRGDVALLHSGIEQIEALTGVPVLGVMPWLDLDLDDEDGVA
HHHHHCCCHHHHCEEEEEHHCCHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCE
LQKGKYRQTAPRDLDIAVVQLPHISNFTDFNALAAQPDVRVRYVSHPQALADADLVILPG
ECCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHCCCCCCEEEEECCCHHHCCCCEEEECC
SKNTLGDLGWLRESGIAAALLQAHRQRVPVMGICGGYQMLGRTIIDEVESGLGTQPGLGL
CCCCCHHHHHHHHCCHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCHH
LNIVTRFAPRKTTVQSAAQVTMTPPGWLHAAAGVAVKGYEIHMGETQRAADCRPALFIGR
HHHHHHHCCCHHHHHCCCEEEECCCCHHHHHCCCEEEEEEEECCCCCCCCCCCCEEEEEC
DGGRVADGAISDDGLVFGTYLHGLFDSDAFTHAVLDSLRHRKGLAPLERTLDYAAYKAQQ
CCCCEECCCCCCCCEEEHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
IDLLASAMREHIDIKEIYKIMRGHREAEA
HHHHHHHHHHCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TQAMAIMLQGTASDVGKSVLVAGLCRIFYQDGLRTAPFKSQNMALNSGITPDGKEMGRA
CCEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCHHHHCHH
QIFQAQAAGIAPDVRMNPVLLKPTSDRKAQVVLMGEVATDMDAVSYHQYKPRLRERILAV
HHHHHHHCCCCCCCCCCCEEECCCCCCCEEEEEEECHHCCHHHHHHHHHHHHHHHHHHHH
YRSLAQQYQVLVLEGAGSPAEINLRDRDIVNMGMAEMARCPVILVADIDKGGVFASIYGT
HHHHHHCEEEEEEECCCCCCEEEECCCHHHHCCHHHHHCCCEEEEEECCCCCCHHHHHHH
LALLRQGERSRVKGVIINKFRGDVALLHSGIEQIEALTGVPVLGVMPWLDLDLDDEDGVA
HHHHHCCCHHHHCEEEEEHHCCHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCE
LQKGKYRQTAPRDLDIAVVQLPHISNFTDFNALAAQPDVRVRYVSHPQALADADLVILPG
ECCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHCCCCCCEEEEECCCHHHCCCCEEEECC
SKNTLGDLGWLRESGIAAALLQAHRQRVPVMGICGGYQMLGRTIIDEVESGLGTQPGLGL
CCCCCHHHHHHHHCCHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCHH
LNIVTRFAPRKTTVQSAAQVTMTPPGWLHAAAGVAVKGYEIHMGETQRAADCRPALFIGR
HHHHHHHCCCHHHHHCCCEEEECCCCHHHHHCCCEEEEEEEECCCCCCCCCCCCEEEEEC
DGGRVADGAISDDGLVFGTYLHGLFDSDAFTHAVLDSLRHRKGLAPLERTLDYAAYKAQQ
CCCCEECCCCCCCCEEEHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
IDLLASAMREHIDIKEIYKIMRGHREAEA
HHHHHHHHHHCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; adenosylcobyrinic acid a,c-diamide; L-glutamine; H2O

Specific reaction: 4 ATP + adenosylcobyrinic acid a,c-diamide + 4 L-glutamine + 4 H2O = 4 ADP + 4 phosphate + adenosylcobyric acid + 4 L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8501034; 11677609 [H]