Click here to switch to the map view.

The map label for this gene is cobU [H]

Identifier: 238920074

GI number: 238920074

Start: 2106048

End: 2106593

Strand: Reverse

Name: cobU [H]

Synonym: NT01EI_2179

Alternate gene names: 238920074

Gene position: 2106593-2106048 (Counterclockwise)

Preceding gene: 238920075

Following gene: 238920071

Centisome position: 55.26

GC content: 66.3

Gene sequence:

>546_bases
ATGATTTTGGTTACCGGAGGGGCGCGCAGCGGAAAGAGCGCGCATGTCGAGCGGCTGGCAGCTCAGCGCTGCGCGCGCAT
TCTGTATATTGCGACCTCCACCGTCACCGATGACGAGATGGCGGCGCGCATCGAGAAGCACCGCGCGCAGCGGCCGGCGC
ACTGGCGCACCTGGGAGGGGTATCGCGATCTGGGCGGGGTGATTCGCCACCGGGTACGACCCGGCGAGGGGGTGGTGCTG
GAGTGCATCACCACCATGCTGGCCAACCTGCTCTATGAGGCCAGCGGCGGCGCATCGCCGGAGACCCTGGATTTTCCCGC
GCTTGAGGTGGTGCTGCAACGGCAGGTGGACGATCTGATCGCGGCGTGCCGGGCGTCGTCGTCGCCGGTGTATATCGTGA
CCAATGAGCTGGGCATGAGCATCACCCCGGAGAATCGGCTGGCGCGCCACTTTGTCGATATCGCCGGCCGGGCGAACCAA
CGGCTGGCGCAGGCGGCGCAGGAGGTGTGGCTGGTGGTGTCCGGGATCGGCGTACAGATTAAATAG

Upstream 100 bases:

>100_bases
ACAAAGCCCAACAGATCGATCTTCTGGCCAGTGCAATGAGAGAGCATATTGATATTAAAGAAATTTATAAAATAATGCGC
GGGCATCGGGAGGCGGAGGC

Downstream 100 bases:

>100_bases
GGGAGAGCCTCGCCCGGGCTGAGACAGTGTAGCGCTGCAGGTAACGCTGGCCGGGTTGGTGATGCACGGGTGTGGGGACG
ATGGCGGGCGTGAAGGCGTT

Product: adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MILVTGGARSGKSAHVERLAAQRCARILYIATSTVTDDEMAARIEKHRAQRPAHWRTWEGYRDLGGVIRHRVRPGEGVVL
ECITTMLANLLYEASGGASPETLDFPALEVVLQRQVDDLIAACRASSSPVYIVTNELGMSITPENRLARHFVDIAGRANQ
RLAQAAQEVWLVVSGIGVQIK

Sequences:

>Translated_181_residues
MILVTGGARSGKSAHVERLAAQRCARILYIATSTVTDDEMAARIEKHRAQRPAHWRTWEGYRDLGGVIRHRVRPGEGVVL
ECITTMLANLLYEASGGASPETLDFPALEVVLQRQVDDLIAACRASSSPVYIVTNELGMSITPENRLARHFVDIAGRANQ
RLAQAAQEVWLVVSGIGVQIK
>Mature_181_residues
MILVTGGARSGKSAHVERLAAQRCARILYIATSTVTDDEMAARIEKHRAQRPAHWRTWEGYRDLGGVIRHRVRPGEGVVL
ECITTMLANLLYEASGGASPETLDFPALEVVLQRQVDDLIAACRASSSPVYIVTNELGMSITPENRLARHFVDIAGRANQ
RLAQAAQEVWLVVSGIGVQIK

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=181, Percent_Identity=57.4585635359116, Blast_Score=209, Evalue=1e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 19828; Mature: 19828

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILVTGGARSGKSAHVERLAAQRCARILYIATSTVTDDEMAARIEKHRAQRPAHWRTWEG
CEEEECCCCCCCHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHCCCCCCCCCCC
YRDLGGVIRHRVRPGEGVVLECITTMLANLLYEASGGASPETLDFPALEVVLQRQVDDLI
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
AACRASSSPVYIVTNELGMSITPENRLARHFVDIAGRANQRLAQAAQEVWLVVSGIGVQI
HHHHCCCCCEEEEECCCCCEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEE
K
C
>Mature Secondary Structure
MILVTGGARSGKSAHVERLAAQRCARILYIATSTVTDDEMAARIEKHRAQRPAHWRTWEG
CEEEECCCCCCCHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHCCCCCCCCCCC
YRDLGGVIRHRVRPGEGVVLECITTMLANLLYEASGGASPETLDFPALEVVLQRQVDDLI
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
AACRASSSPVYIVTNELGMSITPENRLARHFVDIAGRANQRLAQAAQEVWLVVSGIGVQI
HHHHCCCCCEEEEECCCCCEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEE
K
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8501034; 11677609; 9601028; 10529169 [H]