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The map label for this gene is hlyD [H]

Identifier: 238920045

GI number: 238920045

Start: 2078636

End: 2079973

Strand: Reverse

Name: hlyD [H]

Synonym: NT01EI_2148

Alternate gene names: 238920045

Gene position: 2079973-2078636 (Counterclockwise)

Preceding gene: 238920046

Following gene: 238920040

Centisome position: 54.56

GC content: 53.44

Gene sequence:

>1338_bases
TTGTATACGCTGTGTATATTTACGGTTCTGGCGTTTGCCTGGTCGTTCTTTGGTCGCATCGATATCATAGCCACAGCACC
GGGGAAAGTTCAGCCGCAGGGATACGTTAAGGTGATTGAGTCGGAGGTGACCGGAAAAGTTTCCCGGATCCTGCTGAAAA
ATGGGGATCGCGTCAGTGAGGGAGAGACGGTGGCTCTGTTGGATGCCGCCGATAGTCAGGCGAAATACAACGATGCCCTC
TATAATTTTTCCTCTTTTTATGCAGAGTTATGGCGCAGGAAAACACAGGACAGGCTGGCCCGGGATTTGTCGGTGGAGGA
TCGGGCGATAACGGACTTTGCCGTCGAATGGCCGGCACAGCCGCTCCTGCCGGAGGAGATTAAACACCGTGAAACCAGTG
CGATGCATGGAGAGCTGACGCAGTTAAATACGGACTTGCAGAATATACGTGCACAGTTGGCGCAAAATACAACCCGTGAA
CAGGGAATGAAGGCAACCATCGCGAGCCAAAAAAGCCTGATTGAGACACTTAATGAGCGCCTGCAGATCCGACGGACCCT
GGTGGAAAAGCAGGTGGTCTCCAAGGATGACTGGCTACAGATAATGACGGATGTCAAAGAGGCCAAAAGCACATTACAGT
CTACGTTGGCCCAGTTGCGGGATATTCAGGCCGCCCGGGATATTCTGCAGATCGCACTGCTGAAAACCCGCCATGATTTT
ATCTCTGAAAACCTGAAAAATATTGGGCAGGTGGAGCGGCAAAGCAACAGCCTGCGGGAGCAGGTGAACCAGCGGGAGGC
GCAGCTGGCCCTGATGACATTCAAAAGCCCGATCAACGGAACGATTGTGGCATCCAGCCTGGTGTCACAGGGGCAGGTGG
TGACCCCGGGTGAAGAGCTCATGCGTGTTGTGCCGGACAACAGCCGGCTGGAAATCATTGCCTATGTTCCCAATCAGGAT
ATTGGCTTTATCCGGCCGGGACAGCCTGTTGATGTAAAAATCAATGCGTTTCCCTACACCCGCTATGGCACATTGAATGG
CGTGGTACAGCATATTTCCCAAGATGCCATCCCGGCAGCAGATGCACAGCAGGTGCAAATGGATCCTACCCGTCTTGGCA
GTAACACCAAGGCTGGGGGCGGGCAAAGTACCCAGGGATTGGTGTTTCCCCTGACGGTTGCGCTGGAGCAGGATCATATT
CTGGTCGGTAACCAACAGGTCAGTCTGGTGTCGGGAATGGGGGTGAGCGTTGAGATTAAAACCGATCGCCGGCGTCTGAT
TGATTATCTGGTATCGCCGATTTACGACCTGACTTCCAGTTCATTGCGGGAGCGCTGA

Upstream 100 bases:

>100_bases
ATTAAACTGGAGAAATAAGAATTTTACGGATGACATGGCCTTTTTGCCTTCAGTCATTGAGGTGATAGAATCTCCGCCCT
CACCGGTCAGGGTCCAGTTG

Downstream 100 bases:

>100_bases
TGGCCGATGCCTGCCCGGGTTTCCGGGCAGGCAGGGGGCCGGACTCCGTTGAATTCGTCGTTGATCCCCACATTGCACTC
CAGCGAGTTATCATTAAAGG

Product: type I secretion membrane fusion protein, HlyD family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MYTLCIFTVLAFAWSFFGRIDIIATAPGKVQPQGYVKVIESEVTGKVSRILLKNGDRVSEGETVALLDAADSQAKYNDAL
YNFSSFYAELWRRKTQDRLARDLSVEDRAITDFAVEWPAQPLLPEEIKHRETSAMHGELTQLNTDLQNIRAQLAQNTTRE
QGMKATIASQKSLIETLNERLQIRRTLVEKQVVSKDDWLQIMTDVKEAKSTLQSTLAQLRDIQAARDILQIALLKTRHDF
ISENLKNIGQVERQSNSLREQVNQREAQLALMTFKSPINGTIVASSLVSQGQVVTPGEELMRVVPDNSRLEIIAYVPNQD
IGFIRPGQPVDVKINAFPYTRYGTLNGVVQHISQDAIPAADAQQVQMDPTRLGSNTKAGGGQSTQGLVFPLTVALEQDHI
LVGNQQVSLVSGMGVSVEIKTDRRRLIDYLVSPIYDLTSSSLRER

Sequences:

>Translated_445_residues
MYTLCIFTVLAFAWSFFGRIDIIATAPGKVQPQGYVKVIESEVTGKVSRILLKNGDRVSEGETVALLDAADSQAKYNDAL
YNFSSFYAELWRRKTQDRLARDLSVEDRAITDFAVEWPAQPLLPEEIKHRETSAMHGELTQLNTDLQNIRAQLAQNTTRE
QGMKATIASQKSLIETLNERLQIRRTLVEKQVVSKDDWLQIMTDVKEAKSTLQSTLAQLRDIQAARDILQIALLKTRHDF
ISENLKNIGQVERQSNSLREQVNQREAQLALMTFKSPINGTIVASSLVSQGQVVTPGEELMRVVPDNSRLEIIAYVPNQD
IGFIRPGQPVDVKINAFPYTRYGTLNGVVQHISQDAIPAADAQQVQMDPTRLGSNTKAGGGQSTQGLVFPLTVALEQDHI
LVGNQQVSLVSGMGVSVEIKTDRRRLIDYLVSPIYDLTSSSLRER
>Mature_445_residues
MYTLCIFTVLAFAWSFFGRIDIIATAPGKVQPQGYVKVIESEVTGKVSRILLKNGDRVSEGETVALLDAADSQAKYNDAL
YNFSSFYAELWRRKTQDRLARDLSVEDRAITDFAVEWPAQPLLPEEIKHRETSAMHGELTQLNTDLQNIRAQLAQNTTRE
QGMKATIASQKSLIETLNERLQIRRTLVEKQVVSKDDWLQIMTDVKEAKSTLQSTLAQLRDIQAARDILQIALLKTRHDF
ISENLKNIGQVERQSNSLREQVNQREAQLALMTFKSPINGTIVASSLVSQGQVVTPGEELMRVVPDNSRLEIIAYVPNQD
IGFIRPGQPVDVKINAFPYTRYGTLNGVVQHISQDAIPAADAQQVQMDPTRLGSNTKAGGGQSTQGLVFPLTVALEQDHI
LVGNQQVSLVSGMGVSVEIKTDRRRLIDYLVSPIYDLTSSSLRER

Specific function: Involved in the transport of hemolysin A [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 49664; Mature: 49664

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTLCIFTVLAFAWSFFGRIDIIATAPGKVQPQGYVKVIESEVTGKVSRILLKNGDRVSE
CHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
GETVALLDAADSQAKYNDALYNFSSFYAELWRRKTQDRLARDLSVEDRAITDFAVEWPAQ
CCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHEEECCCC
PLLPEEIKHRETSAMHGELTQLNTDLQNIRAQLAQNTTREQGMKATIASQKSLIETLNER
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHH
LQIRRTLVEKQVVSKDDWLQIMTDVKEAKSTLQSTLAQLRDIQAARDILQIALLKTRHDF
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISENLKNIGQVERQSNSLREQVNQREAQLALMTFKSPINGTIVASSLVSQGQVVTPGEEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHCCCEECCHHHH
MRVVPDNSRLEIIAYVPNQDIGFIRPGQPVDVKINAFPYTRYGTLNGVVQHISQDAIPAA
HHHCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCC
DAQQVQMDPTRLGSNTKAGGGQSTQGLVFPLTVALEQDHILVGNQQVSLVSGMGVSVEIK
CCHHEECCHHHCCCCCCCCCCCCCCCEEEEEEEEECCCEEEECCCEEEEEECCCEEEEEC
TDRRRLIDYLVSPIYDLTSSSLRER
CHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYTLCIFTVLAFAWSFFGRIDIIATAPGKVQPQGYVKVIESEVTGKVSRILLKNGDRVSE
CHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
GETVALLDAADSQAKYNDALYNFSSFYAELWRRKTQDRLARDLSVEDRAITDFAVEWPAQ
CCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHEEECCCC
PLLPEEIKHRETSAMHGELTQLNTDLQNIRAQLAQNTTREQGMKATIASQKSLIETLNER
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHH
LQIRRTLVEKQVVSKDDWLQIMTDVKEAKSTLQSTLAQLRDIQAARDILQIALLKTRHDF
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISENLKNIGQVERQSNSLREQVNQREAQLALMTFKSPINGTIVASSLVSQGQVVTPGEEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHCCCEECCHHHH
MRVVPDNSRLEIIAYVPNQDIGFIRPGQPVDVKINAFPYTRYGTLNGVVQHISQDAIPAA
HHHCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCC
DAQQVQMDPTRLGSNTKAGGGQSTQGLVFPLTVALEQDHILVGNQQVSLVSGMGVSVEIK
CCHHEECCHHHCCCCCCCCCCCCCCCEEEEEEEEECCCEEEECCCEEEEEECCCEEEEEC
TDRRRLIDYLVSPIYDLTSSSLRER
CHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3891743; 1495479 [H]