Click here to switch to the map view.

The map label for this gene is iolB [H]

Identifier: 238920024

GI number: 238920024

Start: 2054920

End: 2055735

Strand: Reverse

Name: iolB [H]

Synonym: NT01EI_2128

Alternate gene names: 238920024

Gene position: 2055735-2054920 (Counterclockwise)

Preceding gene: 238920025

Following gene: 238920023

Centisome position: 53.92

GC content: 62.01

Gene sequence:

>816_bases
ATGTCACGTTTACTTTCGCGCTGGCAGCCGCCGGACGCACAAGGGTGCACCCAATCCATTACGCCAGAGCGTGCGGGCTG
GGGCCATGTTGGCTTTGCGGTGTTTGAACTGGAGGCGGGGCGGCAGTTAACGCTGCCTGCAGTCAGTGAAGAGCGCTGCC
TGGTGCTGGTGGCCGGTCGGGCCTCCATCACTGCACCGACCGCGCGGTTCGCCAATATCGGCGAGCGGATGAGCCCGTTC
GAGCGGAAAAAACCGTGGGCGGTATACGTCGCGCCCGGCGAAACCGTGCAGGTACAGGCCGAGACCCGGCTTGAGCTGGC
GGTGTGCGCCGCGCCCAGCCAAGGTACCTGGCCGACCCGGCTGATCGCGCCGCAGGATATCGATGCCGAAGCCCGCGGCA
AGGGAAACAACCGGCGCTATGTGCACAACATTCTGCCGCAGGATAAACCCGCGGACAGCCTGCTGGTGGTGGAGGTATGG
ACTGACGAAGGCTGTACCAGTTCCTATCCCAGCCATAAGCATGATACCGACAACCCACCGCAGGAAACCTGCCTTGAGGA
GACCTATTACCACCGCCTCAATCCGGAGCAGGGATTCTGTATGCAGCGGGTATATACCGACGATCGGGCGCTTGATGAGT
GCATGGCGGTGTACAACCGCGACGTGGTGATGGTGCCGCAGGGGTATCACCCGGTGGCGACGATGGCGGGCTACGACAGC
TATTACCTCAACGTCATGGCCGGTCCGGTACGGCGCTGGATGTTCACCTGGGAGGCGTGTCATGGCTGGATTAATCAGGA
TTATCCGCGCAAGTAA

Upstream 100 bases:

>100_bases
GCAGGATCCGGCGGTCGCCCATCCATTGACCTACGCGCGTCTGGGGTATAACAACCTGAGCCGTCTGGCGCGTGAGGCCG
GGCTTATCTGAGGAGGCGAT

Downstream 100 bases:

>100_bases
TGCGTGGATGATATCCGGCTGGGTCCCACCAGGGTGTGGCGATACTTCGTCATACACGGCTTTATTGTTTTACGGCGCGC
AAAGGTGAGGGGGAATGACG

Product: protein IolB

Products: NA

Alternate protein names: 5DG isomerase [H]

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MSRLLSRWQPPDAQGCTQSITPERAGWGHVGFAVFELEAGRQLTLPAVSEERCLVLVAGRASITAPTARFANIGERMSPF
ERKKPWAVYVAPGETVQVQAETRLELAVCAAPSQGTWPTRLIAPQDIDAEARGKGNNRRYVHNILPQDKPADSLLVVEVW
TDEGCTSSYPSHKHDTDNPPQETCLEETYYHRLNPEQGFCMQRVYTDDRALDECMAVYNRDVVMVPQGYHPVATMAGYDS
YYLNVMAGPVRRWMFTWEACHGWINQDYPRK

Sequences:

>Translated_271_residues
MSRLLSRWQPPDAQGCTQSITPERAGWGHVGFAVFELEAGRQLTLPAVSEERCLVLVAGRASITAPTARFANIGERMSPF
ERKKPWAVYVAPGETVQVQAETRLELAVCAAPSQGTWPTRLIAPQDIDAEARGKGNNRRYVHNILPQDKPADSLLVVEVW
TDEGCTSSYPSHKHDTDNPPQETCLEETYYHRLNPEQGFCMQRVYTDDRALDECMAVYNRDVVMVPQGYHPVATMAGYDS
YYLNVMAGPVRRWMFTWEACHGWINQDYPRK
>Mature_270_residues
SRLLSRWQPPDAQGCTQSITPERAGWGHVGFAVFELEAGRQLTLPAVSEERCLVLVAGRASITAPTARFANIGERMSPFE
RKKPWAVYVAPGETVQVQAETRLELAVCAAPSQGTWPTRLIAPQDIDAEARGKGNNRRYVHNILPQDKPADSLLVVEVWT
DEGCTSSYPSHKHDTDNPPQETCLEETYYHRLNPEQGFCMQRVYTDDRALDECMAVYNRDVVMVPQGYHPVATMAGYDSY
YLNVMAGPVRRWMFTWEACHGWINQDYPRK

Specific function: Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate) [H]

COG id: COG3718

COG function: function code G; Uncharacterized enzyme involved in inositol metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isomerase iolB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR021120
- InterPro:   IPR014710 [H]

Pfam domain/function: PF04962 KduI [H]

EC number: NA

Molecular weight: Translated: 30636; Mature: 30505

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLLSRWQPPDAQGCTQSITPERAGWGHVGFAVFELEAGRQLTLPAVSEERCLVLVAGR
CCHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEECCCCCCCCEEEEEECC
ASITAPTARFANIGERMSPFERKKPWAVYVAPGETVQVQAETRLELAVCAAPSQGTWPTR
CCCCCCHHHHHHHHHHCCHHHHCCCEEEEECCCCEEEEEECCCEEEEEEECCCCCCCCEE
LIAPQDIDAEARGKGNNRRYVHNILPQDKPADSLLVVEVWTDEGCTSSYPSHKHDTDNPP
EECCCCCCHHHCCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCH
QETCLEETYYHRLNPEQGFCMQRVYTDDRALDECMAVYNRDVVMVPQGYHPVATMAGYDS
HHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHCCCEEEECCCCCCHHHHCCCCC
YYLNVMAGPVRRWMFTWEACHGWINQDYPRK
EEEEEHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SRLLSRWQPPDAQGCTQSITPERAGWGHVGFAVFELEAGRQLTLPAVSEERCLVLVAGR
CHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEECCCCCCCCEEEEEECC
ASITAPTARFANIGERMSPFERKKPWAVYVAPGETVQVQAETRLELAVCAAPSQGTWPTR
CCCCCCHHHHHHHHHHCCHHHHCCCEEEEECCCCEEEEEECCCEEEEEEECCCCCCCCEE
LIAPQDIDAEARGKGNNRRYVHNILPQDKPADSLLVVEVWTDEGCTSSYPSHKHDTDNPP
EECCCCCCHHHCCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCH
QETCLEETYYHRLNPEQGFCMQRVYTDDRALDECMAVYNRDVVMVPQGYHPVATMAGYDS
HHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHCCCEEEECCCCCCHHHHCCCCC
YYLNVMAGPVRRWMFTWEACHGWINQDYPRK
EEEEEHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA