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The map label for this gene is ureC

Identifier: 238919957

GI number: 238919957

Start: 1982413

End: 1984131

Strand: Reverse

Name: ureC

Synonym: NT01EI_2061

Alternate gene names: 238919957

Gene position: 1984131-1982413 (Counterclockwise)

Preceding gene: 238919958

Following gene: 238919956

Centisome position: 52.05

GC content: 48.46

Gene sequence:

>1719_bases
ATGCCACATGTTTCGCGGAAAGAGTATTCTAGTCTGTTTGGCCCAACAGTCGGTGATAAAATTCGCCTGGGGAATACGGA
ACTATTTATTGAAATTGAAAAAGACTTGCGCGGTTATGGTGATGAGTCTGTATATGGTGGTGGGAAATCCCTGCGTGATG
GTATGGGGGCGAATAATAACCTGACCCGTGACAATGGTGTATTGGACCTGGTCATTACTAATGTTACCATCATTGATGCC
TGTTTAGGTGTAATTAAAGCAGATGTGGGTATTAAAGACGGGAAAATTTCCGGTATTGGGAAAAGTGGTAACCCTAATAC
TATGGATGGCGTAACCCCGACAATGGTAGTAGGTGCCAGTACTGATGCTATTTCCGGTGAGCATTTAATTTTGACTGCTG
CAGGTATTGATACCCATATCCATTTAATTTCACCTCAACAGGCTTATCATGCTCTGTCTAATGGCGTCACGACATTCTTT
GGCGGCGGCATTGGACCTACAGATGGTTCTAATGGAACGACGGTTACGGCGGGGCCGTGGAATATTCGTCAAATGCTCCG
CAGCTTTGAGAGCCTGCCGCTAAATGTGGGTCTGTTGGGTAAAGGTAATGCCTGTGGCTATGGTCCGCTGGAAGAGCAAA
TCATTGCAGGGGCGGCTGGCTTGAAGGTGCATGAAGACTGGGGCGCTACAGCGAGTGCACTGCGTTATGCACTGCGCATT
GCCGATAAGATGGATATTCAGGTGGCAGTGCATACTGACAGCCTGAACGAAGGGGGATATGTAGAGGATACTATTGACGC
CTTCGAAGGCCGTACGGTACATACCTTTCATACCGAGGGGGCTGGGGGGGGGCATGCGCCGGATATCATCAAGGTAGCCA
GCCTGATGAATGTGCTACCCAGCTCAACGAACCCAACGCTTCCATTCGGTATCAACAGCCAGGCTGAGCTGTTCGATATG
ATCATGATTTGCCATAACCTTAATCCTAATGTTCCGGCCGATGTTGCCTTTGCTGAAAGTCGCGTTCGTCCGGAGACTAT
CGCTGCAGAAAACGTGTTGCAAGATATGGGGGTCATCTCCATGTTCTCCAGCGACTCCCAAGCGATGGGACGCGTCGGTG
AAAACTGGTTGCGTTTGATTCAAACAGCCAATGCGATGAAAGTGGCTCGCGGCAAGTTACCGGAGGATGCAGCCGGCAAT
GACAACTTCCGAGTGTTACGTTATGTAGCAAAAATCACCATTAACCCTGCCATTGCTCAAGGTGTCAGCCATGTGATTGG
CTCCATCGAGGTTGGGAAAATGGCGGATCTTGTTCTATGGGATCCGCGCTTCTTTGGGGCAAAACCTAAAATGGTTATTA
AGGGAGGTATGATTAGCTGGAGCACGATGGGGGATTCCAACGCGTCGCTGCCGACGACTCAGCCAATCACATATCGTCCT
ATGTTCGGTGCGATGGGCAAAACTATGAATGACACTTGCGTGACGTTCGTTTCTCAGGCTTCGCTGGAAGATGGCGTTCG
CGAGAAGGCGGGATTGGATCGTAACGTTATTGCAGTGAAAAATTGCCGTAATGTTTCAAAACAAGATTTAGTCCGTAATA
ACAACATGCCTAATATTGATGTGGATCCAGAAACCTTTGCTGTAAAGGTGGATGGTGTTCACGCGACGTGTAAGCCTGTT
GATATTGCAGCGATGAATCAACTTTATTTCTTCGGTTAA

Upstream 100 bases:

>100_bases
TGGCAAAGAAGCGGTCGTTGAGAAAGCCATCAAATCCGGATTTAAGTTTTCCAAATAAAAATGATAGCGATATTCAACAT
AGATATTAACGAGGTATATC

Downstream 100 bases:

>100_bases
GTTTAATATCACCTCTCCCTTATTATAGGGAGAGGTGGGTAAAATGGAGTACTCATCATGATCGTGATTAGCCATGTATT
AGGAAATGTGAAAACGGACC

Product: urease subunit alpha

Products: NA

Alternate protein names: Urea amidohydrolase subunit alpha

Number of amino acids: Translated: 572; Mature: 571

Protein sequence:

>572_residues
MPHVSRKEYSSLFGPTVGDKIRLGNTELFIEIEKDLRGYGDESVYGGGKSLRDGMGANNNLTRDNGVLDLVITNVTIIDA
CLGVIKADVGIKDGKISGIGKSGNPNTMDGVTPTMVVGASTDAISGEHLILTAAGIDTHIHLISPQQAYHALSNGVTTFF
GGGIGPTDGSNGTTVTAGPWNIRQMLRSFESLPLNVGLLGKGNACGYGPLEEQIIAGAAGLKVHEDWGATASALRYALRI
ADKMDIQVAVHTDSLNEGGYVEDTIDAFEGRTVHTFHTEGAGGGHAPDIIKVASLMNVLPSSTNPTLPFGINSQAELFDM
IMICHNLNPNVPADVAFAESRVRPETIAAENVLQDMGVISMFSSDSQAMGRVGENWLRLIQTANAMKVARGKLPEDAAGN
DNFRVLRYVAKITINPAIAQGVSHVIGSIEVGKMADLVLWDPRFFGAKPKMVIKGGMISWSTMGDSNASLPTTQPITYRP
MFGAMGKTMNDTCVTFVSQASLEDGVREKAGLDRNVIAVKNCRNVSKQDLVRNNNMPNIDVDPETFAVKVDGVHATCKPV
DIAAMNQLYFFG

Sequences:

>Translated_572_residues
MPHVSRKEYSSLFGPTVGDKIRLGNTELFIEIEKDLRGYGDESVYGGGKSLRDGMGANNNLTRDNGVLDLVITNVTIIDA
CLGVIKADVGIKDGKISGIGKSGNPNTMDGVTPTMVVGASTDAISGEHLILTAAGIDTHIHLISPQQAYHALSNGVTTFF
GGGIGPTDGSNGTTVTAGPWNIRQMLRSFESLPLNVGLLGKGNACGYGPLEEQIIAGAAGLKVHEDWGATASALRYALRI
ADKMDIQVAVHTDSLNEGGYVEDTIDAFEGRTVHTFHTEGAGGGHAPDIIKVASLMNVLPSSTNPTLPFGINSQAELFDM
IMICHNLNPNVPADVAFAESRVRPETIAAENVLQDMGVISMFSSDSQAMGRVGENWLRLIQTANAMKVARGKLPEDAAGN
DNFRVLRYVAKITINPAIAQGVSHVIGSIEVGKMADLVLWDPRFFGAKPKMVIKGGMISWSTMGDSNASLPTTQPITYRP
MFGAMGKTMNDTCVTFVSQASLEDGVREKAGLDRNVIAVKNCRNVSKQDLVRNNNMPNIDVDPETFAVKVDGVHATCKPV
DIAAMNQLYFFG
>Mature_571_residues
PHVSRKEYSSLFGPTVGDKIRLGNTELFIEIEKDLRGYGDESVYGGGKSLRDGMGANNNLTRDNGVLDLVITNVTIIDAC
LGVIKADVGIKDGKISGIGKSGNPNTMDGVTPTMVVGASTDAISGEHLILTAAGIDTHIHLISPQQAYHALSNGVTTFFG
GGIGPTDGSNGTTVTAGPWNIRQMLRSFESLPLNVGLLGKGNACGYGPLEEQIIAGAAGLKVHEDWGATASALRYALRIA
DKMDIQVAVHTDSLNEGGYVEDTIDAFEGRTVHTFHTEGAGGGHAPDIIKVASLMNVLPSSTNPTLPFGINSQAELFDMI
MICHNLNPNVPADVAFAESRVRPETIAAENVLQDMGVISMFSSDSQAMGRVGENWLRLIQTANAMKVARGKLPEDAAGND
NFRVLRYVAKITINPAIAQGVSHVIGSIEVGKMADLVLWDPRFFGAKPKMVIKGGMISWSTMGDSNASLPTTQPITYRPM
FGAMGKTMNDTCVTFVSQASLEDGVREKAGLDRNVIAVKNCRNVSKQDLVRNNNMPNIDVDPETFAVKVDGVHATCKPVD
IAAMNQLYFFG

Specific function: Unknown

COG id: COG0804

COG function: function code E; Urea amidohydrolase (urease) alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 urease domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): URE1_EDWI9 (C5BBR6)

Other databases:

- EMBL:   CP001600
- RefSeq:   YP_002933472.1
- ProteinModelPortal:   C5BBR6
- SMR:   C5BBR6
- GeneID:   7961370
- GenomeReviews:   CP001600_GR
- KEGG:   eic:NT01EI_2061
- OMA:   YGINSQA
- ProtClustDB:   PRK13309
- GO:   GO:0005737
- HAMAP:   MF_01953
- InterPro:   IPR006680
- InterPro:   IPR011059
- InterPro:   IPR011612
- InterPro:   IPR005848
- InterPro:   IPR017951
- InterPro:   IPR017950
- PRINTS:   PR01752
- TIGRFAMs:   TIGR01792

Pfam domain/function: PF01979 Amidohydro_1; PF00449 Urease_alpha; SSF51338 Metalo_hydrolase

EC number: =3.5.1.5

Molecular weight: Translated: 60921; Mature: 60790

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS01120 UREASE_1; PS00145 UREASE_2; PS51368 UREASE_3

Important sites: ACT_SITE 325-325 BINDING 224-224

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHVSRKEYSSLFGPTVGDKIRLGNTELFIEIEKDLRGYGDESVYGGGKSLRDGMGANNN
CCCCCHHHHHHHCCCCCCCEEEECCEEEEEEEEHHHCCCCCCCEECCCHHHHHCCCCCCC
LTRDNGVLDLVITNVTIIDACLGVIKADVGIKDGKISGIGKSGNPNTMDGVTPTMVVGAS
CCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCCCCCCEEEEECC
TDAISGEHLILTAAGIDTHIHLISPQQAYHALSNGVTTFFGGGIGPTDGSNGTTVTAGPW
CCCCCCCEEEEEEECCCEEEEEECCHHHHHHHHCCCCEEECCCCCCCCCCCCCEEEECCH
NIRQMLRSFESLPLNVGLLGKGNACGYGPLEEQIIAGAAGLKVHEDWGATASALRYALRI
HHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHCCCCCEEECCCCCHHHHHHHHHHH
ADKMDIQVAVHTDSLNEGGYVEDTIDAFEGRTVHTFHTEGAGGGHAPDIIKVASLMNVLP
HCCCEEEEEEEECCCCCCCCCHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCC
SSTNPTLPFGINSQAELFDMIMICHNLNPNVPADVAFAESRVRPETIAAENVLQDMGVIS
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHCCHHE
MFSSDSQAMGRVGENWLRLIQTANAMKVARGKLPEDAAGNDNFRVLRYVAKITINPAIAQ
EECCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCHHHHEEHHHHCCCHHHHH
GVSHVIGSIEVGKMADLVLWDPRFFGAKPKMVIKGGMISWSTMGDSNASLPTTQPITYRP
HHHHHHCCCCCCCCEEEEEECCHHCCCCCCEEEECCEEEEEECCCCCCCCCCCCCEEECC
MFGAMGKTMNDTCVTFVSQASLEDGVREKAGLDRNVIAVKNCRNVSKQDLVRNNNMPNID
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHCCCCHHHHHHCCCCCCCC
VDPETFAVKVDGVHATCKPVDIAAMNQLYFFG
CCCCEEEEEECCCEEECCCCCHHHHCEEEECC
>Mature Secondary Structure 
PHVSRKEYSSLFGPTVGDKIRLGNTELFIEIEKDLRGYGDESVYGGGKSLRDGMGANNN
CCCCHHHHHHHCCCCCCCEEEECCEEEEEEEEHHHCCCCCCCEECCCHHHHHCCCCCCC
LTRDNGVLDLVITNVTIIDACLGVIKADVGIKDGKISGIGKSGNPNTMDGVTPTMVVGAS
CCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCCCCCCEEEEECC
TDAISGEHLILTAAGIDTHIHLISPQQAYHALSNGVTTFFGGGIGPTDGSNGTTVTAGPW
CCCCCCCEEEEEEECCCEEEEEECCHHHHHHHHCCCCEEECCCCCCCCCCCCCEEEECCH
NIRQMLRSFESLPLNVGLLGKGNACGYGPLEEQIIAGAAGLKVHEDWGATASALRYALRI
HHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHCCCCCEEECCCCCHHHHHHHHHHH
ADKMDIQVAVHTDSLNEGGYVEDTIDAFEGRTVHTFHTEGAGGGHAPDIIKVASLMNVLP
HCCCEEEEEEEECCCCCCCCCHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCC
SSTNPTLPFGINSQAELFDMIMICHNLNPNVPADVAFAESRVRPETIAAENVLQDMGVIS
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHCCHHE
MFSSDSQAMGRVGENWLRLIQTANAMKVARGKLPEDAAGNDNFRVLRYVAKITINPAIAQ
EECCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCHHHHEEHHHHCCCHHHHH
GVSHVIGSIEVGKMADLVLWDPRFFGAKPKMVIKGGMISWSTMGDSNASLPTTQPITYRP
HHHHHHCCCCCCCCEEEEEECCHHCCCCCCEEEECCEEEEEECCCCCCCCCCCCCEEECC
MFGAMGKTMNDTCVTFVSQASLEDGVREKAGLDRNVIAVKNCRNVSKQDLVRNNNMPNID
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHCCCCHHHHHHCCCCCCCC
VDPETFAVKVDGVHATCKPVDIAAMNQLYFFG
CCCCEEEEEECCCEEECCCCCHHHHCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA