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The map label for this gene is cobT [H]

Identifier: 238919747

GI number: 238919747

Start: 1787876

End: 1788934

Strand: Direct

Name: cobT [H]

Synonym: NT01EI_1851

Alternate gene names: 238919747

Gene position: 1787876-1788934 (Clockwise)

Preceding gene: 238919746

Following gene: 238919748

Centisome position: 46.9

GC content: 67.99

Gene sequence:

>1059_bases
ATGACCCATTATGCACAGACGCTGGCGGAGATCGTCGCCGCCATTCGTCCGCTGGACGACGCGGCACAGGCGCAGGCGCG
CCAGCGCCAAGACAGTTTACTGAAGCCACCCGGCAGTCTGGGACGGCTGGAGCAGCTCGCCGTTCAGCTGGCCGGGATCT
TTGCGCCGCGGCCACCGGTCGTGACGAAGAAACAGATCTTCGTTATCGCCGCCGATCACGGTGTATACCAGGAAGGGGTC
GCCATTTCGCCGCAGGCGGTGACCGCCATCCAGGCGCACAATATGGCGCTGGGGATCACCGGTGTGTGTGTGCTGGCGCA
GCAGGCCGGCGCCGCCGTCACGCTGGTGGATGCCGGCATCGACGCTGATCCCCTGCCGCAGGCGGTCAATATGCGCATGG
GGCGGGGCTGTGGCAATATTGCGCACGGCCCGGCGATGAGCCGGGTGCAGGCCGAAGAGCTGCTGGTGCGCTGCGCCAGG
CTGGCGATGGCGCAGGCCAAGGCGGGGGTCAATCTGATGGGGATCGGCGAACTGGGCATCGCCAATACTACGCCGGCGGC
GGCGCTGGTCAGCGTGCTGACCGGCAGCGTGCCGGCGCAGACGGTGGGGCTGGGCGCCAACCTGCCGGCCGATCGCTTGC
GGCATAAGGTGGCGGTGGTGGAGCAGGCTATCCGTATCAATGCGCCTGACCCCCAAGACGGCGTGGCGACGCTGGCGGCG
CTGGGCGGGTTCGATCTGGTCGGCATGGCCGGCGTGATGATCGGGGCCGCGGCGGCGCGGGTTCCACTGGTGTTGGATGG
CTTTCTCTCCTATGCCGCGGCGCTGGCTGCTTGCCGGATCGCACCGGGGGTGCACCCTTACCTGATCCCGTCGCACCATT
CGGCGGAGAAGGGGGCCGCGCTGGCGCTCGCGGCGCTGGGGCTGACACCGTACCTGCATATGGATATGCGCCTGGGGGAG
GGAAGCGGTGCAGCGCTGATGATGCCGATCGTGGAGGCGGCCTGTGCCCTCCATCAGCGCATGGGGCTACTGAGCCAGAG
CAATATTGTGCTGCCGTAG

Upstream 100 bases:

>100_bases
GATCTATCAGCTGATGCGCGCCCACGCGGGCGGGGCGCCGTCATCATGATGACGCGAACGGTATGCCCCGCATGACATTA
ACCTTAAGAGATACGTAACG

Downstream 100 bases:

>100_bases
TCGTGCGCTAACGGCATGTCCTGCGCATTGACCCGCAGTGATCGCGGTGTGTAGGTATCGTGATCGCCGCGGTAAATGGC
GGGGGAGTAATCAGGGGCGT

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MTHYAQTLAEIVAAIRPLDDAAQAQARQRQDSLLKPPGSLGRLEQLAVQLAGIFAPRPPVVTKKQIFVIAADHGVYQEGV
AISPQAVTAIQAHNMALGITGVCVLAQQAGAAVTLVDAGIDADPLPQAVNMRMGRGCGNIAHGPAMSRVQAEELLVRCAR
LAMAQAKAGVNLMGIGELGIANTTPAAALVSVLTGSVPAQTVGLGANLPADRLRHKVAVVEQAIRINAPDPQDGVATLAA
LGGFDLVGMAGVMIGAAAARVPLVLDGFLSYAAALAACRIAPGVHPYLIPSHHSAEKGAALALAALGLTPYLHMDMRLGE
GSGAALMMPIVEAACALHQRMGLLSQSNIVLP

Sequences:

>Translated_352_residues
MTHYAQTLAEIVAAIRPLDDAAQAQARQRQDSLLKPPGSLGRLEQLAVQLAGIFAPRPPVVTKKQIFVIAADHGVYQEGV
AISPQAVTAIQAHNMALGITGVCVLAQQAGAAVTLVDAGIDADPLPQAVNMRMGRGCGNIAHGPAMSRVQAEELLVRCAR
LAMAQAKAGVNLMGIGELGIANTTPAAALVSVLTGSVPAQTVGLGANLPADRLRHKVAVVEQAIRINAPDPQDGVATLAA
LGGFDLVGMAGVMIGAAAARVPLVLDGFLSYAAALAACRIAPGVHPYLIPSHHSAEKGAALALAALGLTPYLHMDMRLGE
GSGAALMMPIVEAACALHQRMGLLSQSNIVLP
>Mature_351_residues
THYAQTLAEIVAAIRPLDDAAQAQARQRQDSLLKPPGSLGRLEQLAVQLAGIFAPRPPVVTKKQIFVIAADHGVYQEGVA
ISPQAVTAIQAHNMALGITGVCVLAQQAGAAVTLVDAGIDADPLPQAVNMRMGRGCGNIAHGPAMSRVQAEELLVRCARL
AMAQAKAGVNLMGIGELGIANTTPAAALVSVLTGSVPAQTVGLGANLPADRLRHKVAVVEQAIRINAPDPQDGVATLAAL
GGFDLVGMAGVMIGAAAARVPLVLDGFLSYAAALAACRIAPGVHPYLIPSHHSAEKGAALALAALGLTPYLHMDMRLGEG
SGAALMMPIVEAACALHQRMGLLSQSNIVLP

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=349, Percent_Identity=61.3180515759312, Blast_Score=414, Evalue=1e-117,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 35993; Mature: 35861

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: PS00136 SUBTILASE_ASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHYAQTLAEIVAAIRPLDDAAQAQARQRQDSLLKPPGSLGRLEQLAVQLAGIFAPRPPV
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCC
VTKKQIFVIAADHGVYQEGVAISPQAVTAIQAHNMALGITGVCVLAQQAGAAVTLVDAGI
CCCCEEEEEEECCCCHHCCCEECCHHHHHHHHCCEEEHHHHHHHHHHHCCCEEEEEECCC
DADPLPQAVNMRMGRGCGNIAHGPAMSRVQAEELLVRCARLAMAQAKAGVNLMGIGELGI
CCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
ANTTPAAALVSVLTGSVPAQTVGLGANLPADRLRHKVAVVEQAIRINAPDPQDGVATLAA
CCCCHHHHHHHHHHCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
LGGFDLVGMAGVMIGAAAARVPLVLDGFLSYAAALAACRIAPGVHPYLIPSHHSAEKGAA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCHHHHH
LALAALGLTPYLHMDMRLGEGSGAALMMPIVEAACALHQRMGLLSQSNIVLP
HHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
THYAQTLAEIVAAIRPLDDAAQAQARQRQDSLLKPPGSLGRLEQLAVQLAGIFAPRPPV
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCC
VTKKQIFVIAADHGVYQEGVAISPQAVTAIQAHNMALGITGVCVLAQQAGAAVTLVDAGI
CCCCEEEEEEECCCCHHCCCEECCHHHHHHHHCCEEEHHHHHHHHHHHCCCEEEEEECCC
DADPLPQAVNMRMGRGCGNIAHGPAMSRVQAEELLVRCARLAMAQAKAGVNLMGIGELGI
CCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
ANTTPAAALVSVLTGSVPAQTVGLGANLPADRLRHKVAVVEQAIRINAPDPQDGVATLAA
CCCCHHHHHHHHHHCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
LGGFDLVGMAGVMIGAAAARVPLVLDGFLSYAAALAACRIAPGVHPYLIPSHHSAEKGAA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCHHHHH
LALAALGLTPYLHMDMRLGEGSGAALMMPIVEAACALHQRMGLLSQSNIVLP
HHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]