Click here to switch to the map view.

The map label for this gene is prc [H]

Identifier: 238919694

GI number: 238919694

Start: 1737904

End: 1739946

Strand: Direct

Name: prc [H]

Synonym: NT01EI_1797

Alternate gene names: 238919694

Gene position: 1737904-1739946 (Clockwise)

Preceding gene: 238919693

Following gene: 238919699

Centisome position: 45.59

GC content: 56.53

Gene sequence:

>2043_bases
ATGAACAATTTTTTCCGGGTATCGGCAATCGCCCTGTCGCTGTTTGCAGGTACCGTTTTTGCAGCGGATGGCGCCGTCAG
CGGCGCTATCCAGCTGCCCCAGTTGCATCAGGAACCTCAGCATGCAACGGTCAGTGAACGTGTTACCGCACGTTTTACCC
GCTCCCATTACCGCCAGTTTGACCTCAACGCAGAGTTCTCGAAGAAAATCTTCAACCGTTACCTGAACATGTTGGACTAT
AACCACAACGTGTTTCTGGCATCGGATATCGCCCGCTTCCGCGATCGTGAAAGCAAGCTGGGTGATGAGCTGCGCAGTGG
TCAGCTGGATACGGCCTATGCGCTGTTCAATCTGTCTCAGCAGCGCCGTCTGGAGCGTTACGAGTATGCCCTGACGCTGC
TGAAAAAACCGATGAGCTTTGACGGCAGTGACACCATCGACGTCGATCGCAGTAAGGCGCCGTGGCCGACCAGTGTTGCC
GAGCTGGATACTCTTTGGCACGCCAAGGTGAAGTATGACGCGTTGAACCTGAAGCTGACCGGTAAGGACTGGCCGGAGAT
CCAGAAGATCCTGACCAAACGCTATCAGTTTGCCATTAAGCGACTGACCCAGGGCAACAGCGAGGATGTCTTCCAGCTGT
TTATGAATGCGTTTGCCCGTGAGATCGATCCCCATACCAGCTACCTGTCGCCACGCAATACCGAGCAGTTCAATACGGAC
ATGAGCCTGTCGCTGGAGGGCATCGGTGCGGTGTTGCAGCAGACCGAGGATGACTATACCCAGATTAACTCTCTGGTGGC
TGGCGGTCCGGCGGCCAAGAGCAAGGTGCTGAAGGTGGGTGATCGCATCGTGGCGGTGGGTCAGCCGGGCAAACCGATGG
TCGATGTGATCGGCTGGCGTCTGGACGACGTGGTCGCCCTGATCAAAGGGCCAAAGGGCAGCAGGGTGCGTCTGGAGATC
CTGTCGGCGGGTAAAGGCACCAAAACCCGTATCGTCACCCTGACCCGCGAACGCATCCGCTTGGAAGATCGTGCCGTGAA
GATGAGTGTCAAAACGGCAGACGGTCATAAAATCGGCGTGCTGGATATTCCCGGTTTCTACGTCGGCCTGACGGAGGACG
TCAAGGTTCAGCTGCAGAAGCTGGAGAAACAGCATGTGAGCGCCATCGTCATCGATCTGCGCGGCAATGGGGGCGGTGCC
CTGACGGAGGCGGTCTCTCTGTCGGGTCTGTTTATACCCAGCGGGCCGGTGGTGCAGGTGCGCGATAACGTTGGCAAGGT
GCGCGGGGATGAAGATACTGATGGCGTCGTCTACTACAAGGGGCCGCTGGTGGTGCTGGTCGATCGCTTTAGCGCCTCGG
CCTCCGAGATTTTCGCTGCCGCAATGCAGGATTACGATCGTGCCTTGATCGTGGGTGAACCCACCTTCGGAAAGGGAACG
GTACAGCAGTACCGGTCAGTGAATCGCATTTACGATCAGATGTTGCGCCCAGAGTGGCCGGATCTGGGATCGGTGCAGTA
CACCATTCAGAAGTTTTACCGCATCAACGGTGGCAGCACCCAGCGGAAAGGGGTAACGCCGGATATCGTGATGCCGACAG
GCGTTGATCCGGCGGACACCGGCGAGAGCTTTGAGGATAATGCGTTGCCGTGGGATAGCATCAACGCCGCCGTCTATAAT
AAGGCCGGTGATGTACAGCGCTTTGATCCGCAGCTGATTGTGCTGCACGATGCGCGCATCGCCAAAGATCCCGAGTTCCA
GTACATCGAGCAGGATATTGCCCACTACAAGGCGCTCAAGGCGCGCCGTAACATTGTTTCTCTGAACTACGCTCAGCGCG
AGAAGGAGAACAAGGATGACGATGCAATTCGTCTGCAGCGGATCAACGCCCGGTTGAAGCTGGCGGGCAAGAAGCCGATC
GTCTCGCTGGATGATATTCCCAAGGATTATCAGGAACCCGATACCTATCTGAATGAAACAGTAAAAATTGCCGAAGATCT
GGCTCTGTTGGAGCAGAAAAGCGCACAGCAGGCTCAGATGTAG

Upstream 100 bases:

>100_bases
GAGATCACCAAAGACGGTGTACGTGTCCAGCTGTCTAACGGTCTGGCAATGATTGTACGCACAGAACACTTGCAGTTCTG
ATACGGAGGCCAACCCAGGC

Downstream 100 bases:

>100_bases
GGGTAAGCAGGGCAATGCTCCAGTGAAAAAAGGCGCGTCGCAGGTCGCGCCTTTTTTATCAGCAGCGCTCGATTTTCATT
GTCACAAAATAAGCGGAAGC

Product: carboxy-terminal protease

Products: NA

Alternate protein names: C-terminal-processing peptidase; PRC protein; Protease Re [H]

Number of amino acids: Translated: 680; Mature: 680

Protein sequence:

>680_residues
MNNFFRVSAIALSLFAGTVFAADGAVSGAIQLPQLHQEPQHATVSERVTARFTRSHYRQFDLNAEFSKKIFNRYLNMLDY
NHNVFLASDIARFRDRESKLGDELRSGQLDTAYALFNLSQQRRLERYEYALTLLKKPMSFDGSDTIDVDRSKAPWPTSVA
ELDTLWHAKVKYDALNLKLTGKDWPEIQKILTKRYQFAIKRLTQGNSEDVFQLFMNAFAREIDPHTSYLSPRNTEQFNTD
MSLSLEGIGAVLQQTEDDYTQINSLVAGGPAAKSKVLKVGDRIVAVGQPGKPMVDVIGWRLDDVVALIKGPKGSRVRLEI
LSAGKGTKTRIVTLTRERIRLEDRAVKMSVKTADGHKIGVLDIPGFYVGLTEDVKVQLQKLEKQHVSAIVIDLRGNGGGA
LTEAVSLSGLFIPSGPVVQVRDNVGKVRGDEDTDGVVYYKGPLVVLVDRFSASASEIFAAAMQDYDRALIVGEPTFGKGT
VQQYRSVNRIYDQMLRPEWPDLGSVQYTIQKFYRINGGSTQRKGVTPDIVMPTGVDPADTGESFEDNALPWDSINAAVYN
KAGDVQRFDPQLIVLHDARIAKDPEFQYIEQDIAHYKALKARRNIVSLNYAQREKENKDDDAIRLQRINARLKLAGKKPI
VSLDDIPKDYQEPDTYLNETVKIAEDLALLEQKSAQQAQM

Sequences:

>Translated_680_residues
MNNFFRVSAIALSLFAGTVFAADGAVSGAIQLPQLHQEPQHATVSERVTARFTRSHYRQFDLNAEFSKKIFNRYLNMLDY
NHNVFLASDIARFRDRESKLGDELRSGQLDTAYALFNLSQQRRLERYEYALTLLKKPMSFDGSDTIDVDRSKAPWPTSVA
ELDTLWHAKVKYDALNLKLTGKDWPEIQKILTKRYQFAIKRLTQGNSEDVFQLFMNAFAREIDPHTSYLSPRNTEQFNTD
MSLSLEGIGAVLQQTEDDYTQINSLVAGGPAAKSKVLKVGDRIVAVGQPGKPMVDVIGWRLDDVVALIKGPKGSRVRLEI
LSAGKGTKTRIVTLTRERIRLEDRAVKMSVKTADGHKIGVLDIPGFYVGLTEDVKVQLQKLEKQHVSAIVIDLRGNGGGA
LTEAVSLSGLFIPSGPVVQVRDNVGKVRGDEDTDGVVYYKGPLVVLVDRFSASASEIFAAAMQDYDRALIVGEPTFGKGT
VQQYRSVNRIYDQMLRPEWPDLGSVQYTIQKFYRINGGSTQRKGVTPDIVMPTGVDPADTGESFEDNALPWDSINAAVYN
KAGDVQRFDPQLIVLHDARIAKDPEFQYIEQDIAHYKALKARRNIVSLNYAQREKENKDDDAIRLQRINARLKLAGKKPI
VSLDDIPKDYQEPDTYLNETVKIAEDLALLEQKSAQQAQM
>Mature_680_residues
MNNFFRVSAIALSLFAGTVFAADGAVSGAIQLPQLHQEPQHATVSERVTARFTRSHYRQFDLNAEFSKKIFNRYLNMLDY
NHNVFLASDIARFRDRESKLGDELRSGQLDTAYALFNLSQQRRLERYEYALTLLKKPMSFDGSDTIDVDRSKAPWPTSVA
ELDTLWHAKVKYDALNLKLTGKDWPEIQKILTKRYQFAIKRLTQGNSEDVFQLFMNAFAREIDPHTSYLSPRNTEQFNTD
MSLSLEGIGAVLQQTEDDYTQINSLVAGGPAAKSKVLKVGDRIVAVGQPGKPMVDVIGWRLDDVVALIKGPKGSRVRLEI
LSAGKGTKTRIVTLTRERIRLEDRAVKMSVKTADGHKIGVLDIPGFYVGLTEDVKVQLQKLEKQHVSAIVIDLRGNGGGA
LTEAVSLSGLFIPSGPVVQVRDNVGKVRGDEDTDGVVYYKGPLVVLVDRFSASASEIFAAAMQDYDRALIVGEPTFGKGT
VQQYRSVNRIYDQMLRPEWPDLGSVQYTIQKFYRINGGSTQRKGVTPDIVMPTGVDPADTGESFEDNALPWDSINAAVYN
KAGDVQRFDPQLIVLHDARIAKDPEFQYIEQDIAHYKALKARRNIVSLNYAQREKENKDDDAIRLQRINARLKLAGKKPI
VSLDDIPKDYQEPDTYLNETVKIAEDLALLEQKSAQQAQM

Specific function: Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3). May be involved in protection of the bacterium from thermal and osmotic stresses [H]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=679, Percent_Identity=73.9322533136966, Blast_Score=1030, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR020992 [H]

Pfam domain/function: PF11818 DUF3340; PF00595 PDZ; PF03572 Peptidase_S41 [H]

EC number: =3.4.21.102 [H]

Molecular weight: Translated: 76183; Mature: 76183

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNFFRVSAIALSLFAGTVFAADGAVSGAIQLPQLHQEPQHATVSERVTARFTRSHYRQF
CCCEEEHHHHHHHHHHHHHEECCCCCCCCEECCHHCCCCCCCHHHHHHHHHHHHHHHHEE
DLNAEFSKKIFNRYLNMLDYNHNVFLASDIARFRDRESKLGDELRSGQLDTAYALFNLSQ
CCCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHH
QRRLERYEYALTLLKKPMSFDGSDTIDVDRSKAPWPTSVAELDTLWHAKVKYDALNLKLT
HHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHCEEEEEEEEEEEC
GKDWPEIQKILTKRYQFAIKRLTQGNSEDVFQLFMNAFAREIDPHTSYLSPRNTEQFNTD
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
MSLSLEGIGAVLQQTEDDYTQINSLVAGGPAAKSKVLKVGDRIVAVGQPGKPMVDVIGWR
CEEEHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHCCCEEEEECCCCCCHHHHHCCC
LDDVVALIKGPKGSRVRLEILSAGKGTKTRIVTLTRERIRLEDRAVKMSVKTADGHKIGV
HHHHHHHHCCCCCCEEEEEEEECCCCCCEEEEEEEHHHHHHHCCEEEEEEEECCCCEEEE
LDIPGFYVGLTEDVKVQLQKLEKQHVSAIVIDLRGNGGGALTEAVSLSGLFIPSGPVVQV
EECCCEEEECCHHHHHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHCCEEEECCCCEEEE
RDNVGKVRGDEDTDGVVYYKGPLVVLVDRFSASASEIFAAAMQDYDRALIVGEPTFGKGT
ECCCCCCCCCCCCCCEEEECCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCCHH
VQQYRSVNRIYDQMLRPEWPDLGSVQYTIQKFYRINGGSTQRKGVTPDIVMPTGVDPADT
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHEECCCCCCCCCCCCCEEECCCCCCCCC
GESFEDNALPWDSINAAVYNKAGDVQRFDPQLIVLHDARIAKDPEFQYIEQDIAHYKALK
CCCCCCCCCCCCCCCHHEECCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHH
ARRNIVSLNYAQREKENKDDDAIRLQRINARLKLAGKKPIVSLDDIPKDYQEPDTYLNET
HHCCEEEECHHHHHCCCCCCHHHHHHHHCCEEEECCCCCEEECCCCCCCCCCCHHHHHHH
VKIAEDLALLEQKSAQQAQM
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNNFFRVSAIALSLFAGTVFAADGAVSGAIQLPQLHQEPQHATVSERVTARFTRSHYRQF
CCCEEEHHHHHHHHHHHHHEECCCCCCCCEECCHHCCCCCCCHHHHHHHHHHHHHHHHEE
DLNAEFSKKIFNRYLNMLDYNHNVFLASDIARFRDRESKLGDELRSGQLDTAYALFNLSQ
CCCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHH
QRRLERYEYALTLLKKPMSFDGSDTIDVDRSKAPWPTSVAELDTLWHAKVKYDALNLKLT
HHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHCEEEEEEEEEEEC
GKDWPEIQKILTKRYQFAIKRLTQGNSEDVFQLFMNAFAREIDPHTSYLSPRNTEQFNTD
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
MSLSLEGIGAVLQQTEDDYTQINSLVAGGPAAKSKVLKVGDRIVAVGQPGKPMVDVIGWR
CEEEHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHCCCEEEEECCCCCCHHHHHCCC
LDDVVALIKGPKGSRVRLEILSAGKGTKTRIVTLTRERIRLEDRAVKMSVKTADGHKIGV
HHHHHHHHCCCCCCEEEEEEEECCCCCCEEEEEEEHHHHHHHCCEEEEEEEECCCCEEEE
LDIPGFYVGLTEDVKVQLQKLEKQHVSAIVIDLRGNGGGALTEAVSLSGLFIPSGPVVQV
EECCCEEEECCHHHHHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHCCEEEECCCCEEEE
RDNVGKVRGDEDTDGVVYYKGPLVVLVDRFSASASEIFAAAMQDYDRALIVGEPTFGKGT
ECCCCCCCCCCCCCCEEEECCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCCHH
VQQYRSVNRIYDQMLRPEWPDLGSVQYTIQKFYRINGGSTQRKGVTPDIVMPTGVDPADT
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHEECCCCCCCCCCCCCEEECCCCCCCCC
GESFEDNALPWDSINAAVYNKAGDVQRFDPQLIVLHDARIAKDPEFQYIEQDIAHYKALK
CCCCCCCCCCCCCCCHHEECCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHH
ARRNIVSLNYAQREKENKDDDAIRLQRINARLKLAGKKPIVSLDDIPKDYQEPDTYLNET
HHCCEEEECHHHHHCCCCCCHHHHHHHHCCEEEECCCCCEEECCCCCCCCCCCHHHHHHH
VKIAEDLALLEQKSAQQAQM
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1856173; 1729701; 9097040; 9278503; 1447154; 10049386; 7499412; 8576225 [H]