Click here to switch to the map view.

The map label for this gene is trpD [H]

Identifier: 238919591

GI number: 238919591

Start: 1650690

End: 1651706

Strand: Reverse

Name: trpD [H]

Synonym: NT01EI_1690

Alternate gene names: 238919591

Gene position: 1651706-1650690 (Counterclockwise)

Preceding gene: 238919592

Following gene: 238919590

Centisome position: 43.33

GC content: 68.63

Gene sequence:

>1017_bases
ATGTCACTGACCTCTGAGCATCTGACCATACTGGATAAGCTATACCGGGCACAGGTAATCAGCCGCGCGGAAAGCCAGCG
GCTCTTTAGCGCCATCGTGCACGGTCATCTGGAGCCGAGCCAGCTGGCCGCCGCGCTGATCAGCATGAAGATCCGCGGCG
AACATCCCGACGAGATCGCCGGCGCCGCCAGCGCGCTGCTGGAGGCGGCACAGCCGTTCCCCCGCCCGGCGTATGAGTTT
GCCGACATCGTCGGCACCGGCGGCGATGGCAGCGACAGCATTAATATCTCGACCGCCAGCGCCTTTGTCGCCGCGGCCTG
CGGCGTACGTATCGCCAAGCACGGCAACCGCAGCGTATCCAGCCGTACCGGATCGTCGGATCTGCTGCAGGCGCTGGGGA
TCCGTCTGGACATGAGCGCCGAGGCGTCGCGCCGGGCGCTGGATGAGCTGGGGCTCTGCTTCCTGTTCGCCCCCCAGTAC
CATAGCGGCTTTCGTCATGCCATGCCGGTGCGCCAGCAGCTCAAGACCCGCACCATCTTTAATCTGCTTGGCCCGCTGAT
CAACCCGGCCCGGCCAACCCGCGCGCTGATCGGCGTCTACAGCCCCGATCGGGTGCTGCCGCTGGCGCAGAGCCTGCGCG
GTCTGGGCTACCAGCATGCGGCCGTCGTGCACGGCGGCGGGCTGGATGAGGTCGCCCTGCACGCCCCGACGCAGGTGGCG
GAGCTGCACCAGGGCGAGATCCGCCACTATCAGCTGACGGCGCACGACTTCGGCCTGCCGGACTATCCCTTAAGCGCGCT
GCGCGGCGGCGCGCCGGAGGAGAACCGTACCCTGTTGACCCGCCTGCTCCAGGGGGTGGGCGCGCCCGCGCATCAGGGCG
CCGTCGCCGCCAACGTGGCGCTGTTGCTGCGCCTGTTCGGCCAGCGCGATCTGGCTGCTAACGCCCGCCAGGCGCTGGAT
GTCCTGCGCAGCGGACGGGCCTATCACTATGTCACCGCCCTGGCCGCCCGCGGCTGA

Upstream 100 bases:

>100_bases
CGCCACAGGGCGCCCGGCTGCTGGATCAGAGCATCGACTGGGCCCGCGCCGCACAGCCCCAACCCCGATTGCCCTCCCTC
AGCGCAGCGGAGGCCCCATC

Downstream 100 bases:

>100_bases
CCACACACAGCGCAAGGAGCCTATCATGACGCAACCCTCACCATTGCCCGCCAGCCTGCTGAGCCGCATCATCGCCGATA
AACGGCGCTGGATCGCCGCC

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: Glutamine amidotransferase; Anthranilate phosphoribosyltransferase [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MSLTSEHLTILDKLYRAQVISRAESQRLFSAIVHGHLEPSQLAAALISMKIRGEHPDEIAGAASALLEAAQPFPRPAYEF
ADIVGTGGDGSDSINISTASAFVAAACGVRIAKHGNRSVSSRTGSSDLLQALGIRLDMSAEASRRALDELGLCFLFAPQY
HSGFRHAMPVRQQLKTRTIFNLLGPLINPARPTRALIGVYSPDRVLPLAQSLRGLGYQHAAVVHGGGLDEVALHAPTQVA
ELHQGEIRHYQLTAHDFGLPDYPLSALRGGAPEENRTLLTRLLQGVGAPAHQGAVAANVALLLRLFGQRDLAANARQALD
VLRSGRAYHYVTALAARG

Sequences:

>Translated_338_residues
MSLTSEHLTILDKLYRAQVISRAESQRLFSAIVHGHLEPSQLAAALISMKIRGEHPDEIAGAASALLEAAQPFPRPAYEF
ADIVGTGGDGSDSINISTASAFVAAACGVRIAKHGNRSVSSRTGSSDLLQALGIRLDMSAEASRRALDELGLCFLFAPQY
HSGFRHAMPVRQQLKTRTIFNLLGPLINPARPTRALIGVYSPDRVLPLAQSLRGLGYQHAAVVHGGGLDEVALHAPTQVA
ELHQGEIRHYQLTAHDFGLPDYPLSALRGGAPEENRTLLTRLLQGVGAPAHQGAVAANVALLLRLFGQRDLAANARQALD
VLRSGRAYHYVTALAARG
>Mature_337_residues
SLTSEHLTILDKLYRAQVISRAESQRLFSAIVHGHLEPSQLAAALISMKIRGEHPDEIAGAASALLEAAQPFPRPAYEFA
DIVGTGGDGSDSINISTASAFVAAACGVRIAKHGNRSVSSRTGSSDLLQALGIRLDMSAEASRRALDELGLCFLFAPQYH
SGFRHAMPVRQQLKTRTIFNLLGPLINPARPTRALIGVYSPDRVLPLAQSLRGLGYQHAAVVHGGGLDEVALHAPTQVAE
LHQGEIRHYQLTAHDFGLPDYPLSALRGGAPEENRTLLTRLLQGVGAPAHQGAVAANVALLLRLFGQRDLAANARQALDV
LRSGRAYHYVTALAARG

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=329, Percent_Identity=74.468085106383, Blast_Score=459, Evalue=1e-131,
Organism=Saccharomyces cerevisiae, GI6320561, Length=275, Percent_Identity=30.1818181818182, Blast_Score=110, Evalue=4e-25,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase; PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =4.1.3.27; =2.4.2.18 [H]

Molecular weight: Translated: 36108; Mature: 35976

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLTSEHLTILDKLYRAQVISRAESQRLFSAIVHGHLEPSQLAAALISMKIRGEHPDEIA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHH
GAASALLEAAQPFPRPAYEFADIVGTGGDGSDSINISTASAFVAAACGVRIAKHGNRSVS
HHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCC
SRTGSSDLLQALGIRLDMSAEASRRALDELGLCFLFAPQYHSGFRHAMPVRQQLKTRTIF
CCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEECCHHHCCHHHHHHHHHHHHHHHHH
NLLGPLINPARPTRALIGVYSPDRVLPLAQSLRGLGYQHAAVVHGGGLDEVALHAPTQVA
HHHHHHCCCCCCCHHHEECCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHCCCHHHH
ELHQGEIRHYQLTAHDFGLPDYPLSALRGGAPEENRTLLTRLLQGVGAPAHQGAVAANVA
HHHHCCCEEEEEEHHHCCCCCCCHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHH
LLLRLFGQRDLAANARQALDVLRSGRAYHYVTALAARG
HHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCC
>Mature Secondary Structure 
SLTSEHLTILDKLYRAQVISRAESQRLFSAIVHGHLEPSQLAAALISMKIRGEHPDEIA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHH
GAASALLEAAQPFPRPAYEFADIVGTGGDGSDSINISTASAFVAAACGVRIAKHGNRSVS
HHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCC
SRTGSSDLLQALGIRLDMSAEASRRALDELGLCFLFAPQYHSGFRHAMPVRQQLKTRTIF
CCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEECCHHHCCHHHHHHHHHHHHHHHHH
NLLGPLINPARPTRALIGVYSPDRVLPLAQSLRGLGYQHAAVVHGGGLDEVALHAPTQVA
HHHHHHCCCCCCCHHHEECCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHCCCHHHH
ELHQGEIRHYQLTAHDFGLPDYPLSALRGGAPEENRTLLTRLLQGVGAPAHQGAVAANVA
HHHHCCCEEEEEEHHHCCCCCCCHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHH
LLLRLFGQRDLAANARQALDVLRSGRAYHYVTALAARG
HHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7038627; 6283099; 9097039; 9278503; 4594441 [H]