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The map label for this gene is tdk [H]

Identifier: 238919565

GI number: 238919565

Start: 1622472

End: 1623059

Strand: Direct

Name: tdk [H]

Synonym: NT01EI_1664

Alternate gene names: 238919565

Gene position: 1622472-1623059 (Clockwise)

Preceding gene: 238919563

Following gene: 238919568

Centisome position: 42.56

GC content: 51.36

Gene sequence:

>588_bases
ATGGCACAACTTTATTTTTATTACTCTGCAATGAATGCCGGGAAATCCACGGCACTGTTACAGTCCTCTTATAACTACCG
CGAGCGGGGAATGCATACCCTGGTATTCACAGCTGAAATAGATAATCGCTATGCGGTGGGGCAGGTCAGCTCACGTATCG
GCCTGCACTCACCTGCAATGCTGTATAATCAGGGGACTGATCTTCTGGCCGAAATCCGTCAGGCGCATCAGCAGCAATGT
GTACACTGCGTTCTGGTTGATGAAAGTCAGTTTCTCACTAAAGCACAGGTTCTGGCGTTGTCGATGGTGGTCGATGATTT
AGATATTCCTGTGCTGTGCTACGGTTTGCGTACTGATTTCCGGGCGGAACTCTTCCCTGGTAGCCAATATTTATTGGCCT
GGGCCGATAAGCTGGTTGAGCTTAAGACTATCTGCCACTGTGGCCGCAAGGCGAATATGGTGCTGCGGCTGGATCAGGAT
GGGCGAGCGCTGAAAGACGGTGAGCAGGTGGTGATCGGCGGCAATGAGCGTTATGTCTCCGTTTGTCGTCGGCACTATAA
GGAAATGCTCGGTGTGACCTCCCGGTAA

Upstream 100 bases:

>100_bases
ATCTGAGCCGGGTCACGGGGAATAACCCGGACATCACGCGGCCCTGCATATATGGTAGAATCCCCCTATACTAGGTGATT
TTTCGGTTTAAGGCTGTTTG

Downstream 100 bases:

>100_bases
CGTCACATCGCTTATCACCATCTGCGCCGCGCAGTTCCTCTCAGCGGCGCGCTTTTCCCCCTATCTCAGTCTCTCCAGCA
CGCGTCGCTGAGGCCATCGC

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MAQLYFYYSAMNAGKSTALLQSSYNYRERGMHTLVFTAEIDNRYAVGQVSSRIGLHSPAMLYNQGTDLLAEIRQAHQQQC
VHCVLVDESQFLTKAQVLALSMVVDDLDIPVLCYGLRTDFRAELFPGSQYLLAWADKLVELKTICHCGRKANMVLRLDQD
GRALKDGEQVVIGGNERYVSVCRRHYKEMLGVTSR

Sequences:

>Translated_195_residues
MAQLYFYYSAMNAGKSTALLQSSYNYRERGMHTLVFTAEIDNRYAVGQVSSRIGLHSPAMLYNQGTDLLAEIRQAHQQQC
VHCVLVDESQFLTKAQVLALSMVVDDLDIPVLCYGLRTDFRAELFPGSQYLLAWADKLVELKTICHCGRKANMVLRLDQD
GRALKDGEQVVIGGNERYVSVCRRHYKEMLGVTSR
>Mature_194_residues
AQLYFYYSAMNAGKSTALLQSSYNYRERGMHTLVFTAEIDNRYAVGQVSSRIGLHSPAMLYNQGTDLLAEIRQAHQQQCV
HCVLVDESQFLTKAQVLALSMVVDDLDIPVLCYGLRTDFRAELFPGSQYLLAWADKLVELKTICHCGRKANMVLRLDQDG
RALKDGEQVVIGGNERYVSVCRRHYKEMLGVTSR

Specific function: Phosphorylates both thymidine and deoxyuridine [H]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family [H]

Homologues:

Organism=Escherichia coli, GI1787490, Length=194, Percent_Identity=77.8350515463918, Blast_Score=316, Evalue=8e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634 [H]

Pfam domain/function: PF00265 TK [H]

EC number: =2.7.1.21 [H]

Molecular weight: Translated: 22062; Mature: 21930

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: PS00603 TK_CELLULAR_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQLYFYYSAMNAGKSTALLQSSYNYRERGMHTLVFTAEIDNRYAVGQVSSRIGLHSPAM
CCEEEEEEEECCCCCCHHHHHCCCCHHHCCCEEEEEEEECCCCEEEHHHHHHCCCCCCHH
LYNQGTDLLAEIRQAHQQQCVHCVLVDESQFLTKAQVLALSMVVDDLDIPVLCYGLRTDF
EECCCHHHHHHHHHHHHHHCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
RAELFPGSQYLLAWADKLVELKTICHCGRKANMVLRLDQDGRALKDGEQVVIGGNERYVS
EEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEEECCCHHHHH
VCRRHYKEMLGVTSR
HHHHHHHHHHCCCCC
>Mature Secondary Structure 
AQLYFYYSAMNAGKSTALLQSSYNYRERGMHTLVFTAEIDNRYAVGQVSSRIGLHSPAM
CEEEEEEEECCCCCCHHHHHCCCCHHHCCCEEEEEEEECCCCEEEHHHHHHCCCCCCHH
LYNQGTDLLAEIRQAHQQQCVHCVLVDESQFLTKAQVLALSMVVDDLDIPVLCYGLRTDF
EECCCHHHHHHHHHHHHHHCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
RAELFPGSQYLLAWADKLVELKTICHCGRKANMVLRLDQDGRALKDGEQVVIGGNERYVS
EEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEEECCCHHHHH
VCRRHYKEMLGVTSR
HHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10222209; 11206551; 11258796 [H]