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The map label for this gene is mdtI [H]

Identifier: 238919517

GI number: 238919517

Start: 1575284

End: 1575613

Strand: Direct

Name: mdtI [H]

Synonym: NT01EI_1613

Alternate gene names: 238919517

Gene position: 1575284-1575613 (Clockwise)

Preceding gene: 238919516

Following gene: 238919519

Centisome position: 41.32

GC content: 61.21

Gene sequence:

>330_bases
ATGTCGTCGCTTGAATGGGTATACGGCGTTTGGCTGGCACTGGCTGTGGCGCTGGAGATCGCGGCCAATATTCTGCTCAA
ATGGTCTGACGGTTTTCGCCACCCACTGCCGGGCGTACTGTCGTTGCTGGCCGTACTGGCCGCCTTTGGGGCGCTGAGTC
AGGCGGTAAAGGGGATTGAACTGTCCGTCGCCTACGCCCTGTGGGGTGGTTTTGGCATTATGGCGACTATCGCGGCGGGC
TGGGTGCTGTTTGGTCAGCGGCTAAACTGCAAGGGGTGGTGCGGGCTGCTGCTGCTGCTGGCCGGTATGGCGGTGATTAA
GCTGGCCTGA

Upstream 100 bases:

>100_bases
CTAGGGCTGCTGGTAGGGGGGATCATCTTGCTGAAGTCCGGTACGGTGAAAAAGAGGCGCTCGCCCTCCAGCCCGGTGAC
GGGGCCGACGGGGAGGAAAC

Downstream 100 bases:

>100_bases
ATTTTGGAGAACGGCCCACTTGCGGGCCGTTTGTTCAGCGGGCGGCGACGATTTTGATCTCTACCCGATACTGCGGGTGC
ATCAGCTTGGCCTGCACGGT

Product: multidrug efflux system protein MdtI

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 109; Mature: 108

Protein sequence:

>109_residues
MSSLEWVYGVWLALAVALEIAANILLKWSDGFRHPLPGVLSLLAVLAAFGALSQAVKGIELSVAYALWGGFGIMATIAAG
WVLFGQRLNCKGWCGLLLLLAGMAVIKLA

Sequences:

>Translated_109_residues
MSSLEWVYGVWLALAVALEIAANILLKWSDGFRHPLPGVLSLLAVLAAFGALSQAVKGIELSVAYALWGGFGIMATIAAG
WVLFGQRLNCKGWCGLLLLLAGMAVIKLA
>Mature_108_residues
SSLEWVYGVWLALAVALEIAANILLKWSDGFRHPLPGVLSLLAVLAAFGALSQAVKGIELSVAYALWGGFGIMATIAAGW
VLFGQRLNCKGWCGLLLLLAGMAVIKLA

Specific function: Catalyzes the excretion of spermidine [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. MdtI subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787883, Length=109, Percent_Identity=73.394495412844, Blast_Score=142, Evalue=4e-36,
Organism=Escherichia coli, GI1786755, Length=99, Percent_Identity=34.3434343434343, Blast_Score=61, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 11499; Mature: 11368

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLEWVYGVWLALAVALEIAANILLKWSDGFRHPLPGVLSLLAVLAAFGALSQAVKGIE
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LSVAYALWGGFGIMATIAAGWVLFGQRLNCKGWCGLLLLLAGMAVIKLA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SSLEWVYGVWLALAVALEIAANILLKWSDGFRHPLPGVLSLLAVLAAFGALSQAVKGIE
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LSVAYALWGGFGIMATIAAGWVLFGQRLNCKGWCGLLLLLAGMAVIKLA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA