Click here to switch to the map view.

The map label for this gene is mdtJ [H]

Identifier: 238919516

GI number: 238919516

Start: 1574914

End: 1575297

Strand: Direct

Name: mdtJ [H]

Synonym: NT01EI_1612

Alternate gene names: 238919516

Gene position: 1574914-1575297 (Clockwise)

Preceding gene: 238919515

Following gene: 238919517

Centisome position: 41.31

GC content: 55.99

Gene sequence:

>384_bases
ATGATTTACTGGATTTTCCTGGCATGTGCCATCGTGGCTGAAATTATTGGCACCCTTTCGATGAAATGGGCCAGCGTCAG
CGGGACGATGAGCGGCAATGTCGTCATGCTGCTGATGGTGACCCTTTCTTATATCCTATTGTCCTTTGCGGTTAAGCGGG
TCGCGCTGGGGGTGGCCTATGCCCTGTGGGAGGGGATTGGCATCTTGTTTATTACGCTGTTCAGCGTGCTGTGGTTTGAC
GAGCCAATATCTGTGCTCAAGCTGAGCGGCCTAGGGCTGCTGGTAGGGGGGATCATCTTGCTGAAGTCCGGTACGGTGAA
AAAGAGGCGCTCGCCCTCCAGCCCGGTGACGGGGCCGACGGGGAGGAAACATGTCGTCGCTTGA

Upstream 100 bases:

>100_bases
GCGATGGATTCTTATATCTAACGTTTTGTAAACCCGGCGGTAAGATCAGTGGAATCAAACAATGCACCAATAAATAAAAT
TAAATCATTGGAGAAAGAAT

Downstream 100 bases:

>100_bases
ATGGGTATACGGCGTTTGGCTGGCACTGGCTGTGGCGCTGGAGATCGCGGCCAATATTCTGCTCAAATGGTCTGACGGTT
TTCGCCACCCACTGCCGGGC

Product: spermidine export protein MdtJ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 127; Mature: 127

Protein sequence:

>127_residues
MIYWIFLACAIVAEIIGTLSMKWASVSGTMSGNVVMLLMVTLSYILLSFAVKRVALGVAYALWEGIGILFITLFSVLWFD
EPISVLKLSGLGLLVGGIILLKSGTVKKRRSPSSPVTGPTGRKHVVA

Sequences:

>Translated_127_residues
MIYWIFLACAIVAEIIGTLSMKWASVSGTMSGNVVMLLMVTLSYILLSFAVKRVALGVAYALWEGIGILFITLFSVLWFD
EPISVLKLSGLGLLVGGIILLKSGTVKKRRSPSSPVTGPTGRKHVVA
>Mature_127_residues
MIYWIFLACAIVAEIIGTLSMKWASVSGTMSGNVVMLLMVTLSYILLSFAVKRVALGVAYALWEGIGILFITLFSVLWFD
EPISVLKLSGLGLLVGGIILLKSGTVKKRRSPSSPVTGPTGRKHVVA

Specific function: Catalyzes the excretion of spermidine [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. MdtJ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787884, Length=116, Percent_Identity=66.3793103448276, Blast_Score=146, Evalue=5e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 13628; Mature: 13628

Theoretical pI: Translated: 10.60; Mature: 10.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYWIFLACAIVAEIIGTLSMKWASVSGTMSGNVVMLLMVTLSYILLSFAVKRVALGVAY
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALWEGIGILFITLFSVLWFDEPISVLKLSGLGLLVGGIILLKSGTVKKRRSPSSPVTGPT
HHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
GRKHVVA
CCCCCCC
>Mature Secondary Structure
MIYWIFLACAIVAEIIGTLSMKWASVSGTMSGNVVMLLMVTLSYILLSFAVKRVALGVAY
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALWEGIGILFITLFSVLWFDEPISVLKLSGLGLLVGGIILLKSGTVKKRRSPSSPVTGPT
HHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
GRKHVVA
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA