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The map label for this gene is lolB [H]

Identifier: 238919468

GI number: 238919468

Start: 1523460

End: 1524080

Strand: Reverse

Name: lolB [H]

Synonym: NT01EI_1562

Alternate gene names: 238919468

Gene position: 1524080-1523460 (Counterclockwise)

Preceding gene: 238919474

Following gene: 238919467

Centisome position: 39.98

GC content: 60.55

Gene sequence:

>621_bases
ATGAAAAAGGTAAATATCCTGCGTTTACTGCCAGTTAGCTGTCTGTTGCTCGCTGCCTGCAGCACGCTGCCCGATAAAAA
TAGCGGCGGCAGCGTCAGCTCACCGCAGTGGCAAGCCCACCAGCAGCAGGTAGAAAATATCACGGTTTATCAGACTCGTG
GGGCATTTGCCTATCTTTCCGATAAGCAAAAGGTGTATGCGCGTTTCTTCTGGCAGCAGACGGCCGCCGGACACTATCGC
CTGCTGCTGACCAATCCCCTCGGCAGCACCGAGCTGGAGCTGAACGTTCAACCGGGGGTCGCGCAGATCACCGATAGCCA
GGGACGCCGCTACGTTAGCGACAACGCCACCGTCATGCTCGAAAAGCTCACCGGTATGCAAATCCCGCTGGATAACCTGC
GTCAGTGGATGCTGGGGCTGCCCGGCCAGGCACAGAGTATCCAGCTGGACAGTGCGTACCGCCTGCGCCAGGCGACCTAC
CGCCACGCGGGCCAGACCTGGCAGGTGGACTACCTGAAGTATGACAGCGCCAGCGTCCCGGCCCTGCCGGCCCAGCTGGA
GCTGACCCAGGGCGGCCAGCGGATCAAGCTGAAGATGGACAGCTGGACGCTACGGCCATGA

Upstream 100 bases:

>100_bases
TTTTTATCCTTTTCCCCCGGATAGGCCGCCGCGCCCATTGACGCTCCCCGACAAGCAGGCTAGCGTTAGCCCCAGAGTAT
ACTCACCATGGATTATGAGG

Downstream 100 bases:

>100_bases
TCGACGCGCTGACCCACTGGCCGGCACCGGCCAAGCTGAATCTGTTTCTTTACATCACCGGGCGGCGGGCCGACGGCTAC
CATCTGCTGCAGACCCTGTT

Product: outer membrane lipoprotein LolB

Products: 5-aminolevulinate; CoA; CO2 [C]

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MKKVNILRLLPVSCLLLAACSTLPDKNSGGSVSSPQWQAHQQQVENITVYQTRGAFAYLSDKQKVYARFFWQQTAAGHYR
LLLTNPLGSTELELNVQPGVAQITDSQGRRYVSDNATVMLEKLTGMQIPLDNLRQWMLGLPGQAQSIQLDSAYRLRQATY
RHAGQTWQVDYLKYDSASVPALPAQLELTQGGQRIKLKMDSWTLRP

Sequences:

>Translated_206_residues
MKKVNILRLLPVSCLLLAACSTLPDKNSGGSVSSPQWQAHQQQVENITVYQTRGAFAYLSDKQKVYARFFWQQTAAGHYR
LLLTNPLGSTELELNVQPGVAQITDSQGRRYVSDNATVMLEKLTGMQIPLDNLRQWMLGLPGQAQSIQLDSAYRLRQATY
RHAGQTWQVDYLKYDSASVPALPAQLELTQGGQRIKLKMDSWTLRP
>Mature_206_residues
MKKVNILRLLPVSCLLLAACSTLPDKNSGGSVSSPQWQAHQQQVENITVYQTRGAFAYLSDKQKVYARFFWQQTAAGHYR
LLLTNPLGSTELELNVQPGVAQITDSQGRRYVSDNATVMLEKLTGMQIPLDNLRQWMLGLPGQAQSIQLDSAYRLRQATY
RHAGQTWQVDYLKYDSASVPALPAQLELTQGGQRIKLKMDSWTLRP

Specific function: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the lolA protein [H]

COG id: COG3017

COG function: function code M; Outer membrane lipoprotein involved in outer membrane biogenesis

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolB family [H]

Homologues:

Organism=Escherichia coli, GI1787460, Length=200, Percent_Identity=60.5, Blast_Score=260, Evalue=5e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004565 [H]

Pfam domain/function: PF03550 LolB [H]

EC number: NA

Molecular weight: Translated: 23167; Mature: 23167

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVNILRLLPVSCLLLAACSTLPDKNSGGSVSSPQWQAHQQQVENITVYQTRGAFAYLS
CCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCEEEEEECCEEEEEC
DKQKVYARFFWQQTAAGHYRLLLTNPLGSTELELNVQPGVAQITDSQGRRYVSDNATVML
CHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEEECCCEEEEECCCCCEEECCCCEEEE
EKLTGMQIPLDNLRQWMLGLPGQAQSIQLDSAYRLRQATYRHAGQTWQVDYLKYDSASVP
EECCCCCCCHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHCCCEEEEEEEEECCCCCC
ALPAQLELTQGGQRIKLKMDSWTLRP
CCCCEEEECCCCCEEEEEECCEECCC
>Mature Secondary Structure
MKKVNILRLLPVSCLLLAACSTLPDKNSGGSVSSPQWQAHQQQVENITVYQTRGAFAYLS
CCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCEEEEEECCEEEEEC
DKQKVYARFFWQQTAAGHYRLLLTNPLGSTELELNVQPGVAQITDSQGRRYVSDNATVML
CHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEEECCCEEEEECCCCCEEECCCCEEEE
EKLTGMQIPLDNLRQWMLGLPGQAQSIQLDSAYRLRQATYRHAGQTWQVDYLKYDSASVP
EECCCCCCCHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHCCCEEEEEEEEECCCCCC
ALPAQLELTQGGQRIKLKMDSWTLRP
CCCCEEEECCCCCEEEEEECCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Succinyl-CoA; glycine [C]

Specific reaction: Succinyl-CoA + glycine = 5-aminolevulinate + CoA + CO2 [C]

General reaction: Acyltransferases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA