Click here to switch to the map view.

The map label for this gene is qseD [H]

Identifier: 238919384

GI number: 238919384

Start: 1452628

End: 1453527

Strand: Direct

Name: qseD [H]

Synonym: NT01EI_1478

Alternate gene names: 238919384

Gene position: 1452628-1453527 (Clockwise)

Preceding gene: 238919381

Following gene: 238919385

Centisome position: 38.1

GC content: 63.22

Gene sequence:

>900_bases
ATGGATGTAAAATGGTTGGAGGACTTCATCAGCCTACAGCGGCTGGGCAATTTTTCCGCGGCGGCGCGGGCGCGCAACGT
CACACAGCCCGCCTTTAGCCGCCGGATCCGGGCGCTGGAGATGTGGCTGGGGGTGCCGCTGTTCGATCGCAGCAGCAACC
CCATACTGCTCACCCCCTACGGTGAGAGGTTTCTCCCCTCCGCCGAGGATATTCTGGCGCGGATCCTCGATGTCAAACTG
GACTTTGCCCAGCTGGCGATCCAGTCTGACGAGACGGTGCGTATTGCCAGCCTGCACACCTTTGCCGTCAATATGCTGCC
GATGCTGCTCGACGCCATGGGATCGGCGCTGGAGGGGGTCCGGGTGGTGGTTAACCCGGGGCTGCAGGGGATTGATAACC
ATTTTAATACGCTGCTGGAAAACAGCGCCGATCTGCTGATGGTGTATGATATCGACGGTGCGCGTCCCGGCGTCGCCGAA
AGGGACGGCCTGCAGTCGCACCGGCTGGCCCATGAAACCCTTATCCCGGTCATCTCCCGCACGCTGCTGCAGCGCCACCC
GCCGGGAGAGCCACTGCCCTATCTGGCCTACAGTGATTTCTCCTTTATTGGCCGCGTCGTGGCGCCCCTGTGCCGCCATG
CGCCGCTGCCGATGGTGAAGTGCTATGAGACCAGCATGAGCGAGGGGCTAAAGCATATGGTGCTGCGCGATCGCGGCCTG
GCCTGGCTGCCGCTCTCCATGGTGCATCGGGAGCTGGCCCAGGGAGTGCTATGCAACGCCTTTCCTGACCATCCGCGTCT
GAGCTGCTGTCTGCCGATCCTGCTGTATAAACGCCGTGACAGCCGCCGCCCCGCTGTGGAGCGCTTCTGGCAGGCGGCCA
CGGCATGCCGCCTGCCGTAA

Upstream 100 bases:

>100_bases
TCCCATAGGAATCTATTTGTATCAAATATAATATCACCATTCTTTATGCCACCATTGCTTATTGGGCATGGTGCCATGTC
GCCAGAGCATAGGACGTACA

Downstream 100 bases:

>100_bases
AATCCTATCCTGCCGGGTAGCGCTTACCTGCTCCGTTGATTCTTTTCGCTGATATTGCGTCTGATCGGAGGTGAACGGTG
CGGCTGTCTTTATTGACAAG

Product: hypothetical protein

Products: NA

Alternate protein names: Quorum-sensing regulator protein D [H]

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MDVKWLEDFISLQRLGNFSAAARARNVTQPAFSRRIRALEMWLGVPLFDRSSNPILLTPYGERFLPSAEDILARILDVKL
DFAQLAIQSDETVRIASLHTFAVNMLPMLLDAMGSALEGVRVVVNPGLQGIDNHFNTLLENSADLLMVYDIDGARPGVAE
RDGLQSHRLAHETLIPVISRTLLQRHPPGEPLPYLAYSDFSFIGRVVAPLCRHAPLPMVKCYETSMSEGLKHMVLRDRGL
AWLPLSMVHRELAQGVLCNAFPDHPRLSCCLPILLYKRRDSRRPAVERFWQAATACRLP

Sequences:

>Translated_299_residues
MDVKWLEDFISLQRLGNFSAAARARNVTQPAFSRRIRALEMWLGVPLFDRSSNPILLTPYGERFLPSAEDILARILDVKL
DFAQLAIQSDETVRIASLHTFAVNMLPMLLDAMGSALEGVRVVVNPGLQGIDNHFNTLLENSADLLMVYDIDGARPGVAE
RDGLQSHRLAHETLIPVISRTLLQRHPPGEPLPYLAYSDFSFIGRVVAPLCRHAPLPMVKCYETSMSEGLKHMVLRDRGL
AWLPLSMVHRELAQGVLCNAFPDHPRLSCCLPILLYKRRDSRRPAVERFWQAATACRLP
>Mature_299_residues
MDVKWLEDFISLQRLGNFSAAARARNVTQPAFSRRIRALEMWLGVPLFDRSSNPILLTPYGERFLPSAEDILARILDVKL
DFAQLAIQSDETVRIASLHTFAVNMLPMLLDAMGSALEGVRVVVNPGLQGIDNHFNTLLENSADLLMVYDIDGARPGVAE
RDGLQSHRLAHETLIPVISRTLLQRHPPGEPLPYLAYSDFSFIGRVVAPLCRHAPLPMVKCYETSMSEGLKHMVLRDRGL
AWLPLSMVHRELAQGVLCNAFPDHPRLSCCLPILLYKRRDSRRPAVERFWQAATACRLP

Specific function: Down-regulates expression of the flagellar regulon, decreasing motility [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790783, Length=310, Percent_Identity=32.5806451612903, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI145693105, Length=140, Percent_Identity=27.1428571428571, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788887, Length=110, Percent_Identity=35.4545454545455, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33612; Mature: 33612

Theoretical pI: Translated: 8.15; Mature: 8.15

Prosite motif: PS50931 HTH_LYSR ; PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVKWLEDFISLQRLGNFSAAARARNVTQPAFSRRIRALEMWLGVPLFDRSSNPILLTPY
CCHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEECCC
GERFLPSAEDILARILDVKLDFAQLAIQSDETVRIASLHTFAVNMLPMLLDAMGSALEGV
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCC
RVVVNPGLQGIDNHFNTLLENSADLLMVYDIDGARPGVAERDGLQSHRLAHETLIPVISR
EEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
TLLQRHPPGEPLPYLAYSDFSFIGRVVAPLCRHAPLPMVKCYETSMSEGLKHMVLRDRGL
HHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCC
AWLPLSMVHRELAQGVLCNAFPDHPRLSCCLPILLYKRRDSRRPAVERFWQAATACRLP
EECCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDVKWLEDFISLQRLGNFSAAARARNVTQPAFSRRIRALEMWLGVPLFDRSSNPILLTPY
CCHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEECCC
GERFLPSAEDILARILDVKLDFAQLAIQSDETVRIASLHTFAVNMLPMLLDAMGSALEGV
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCC
RVVVNPGLQGIDNHFNTLLENSADLLMVYDIDGARPGVAERDGLQSHRLAHETLIPVISR
EEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
TLLQRHPPGEPLPYLAYSDFSFIGRVVAPLCRHAPLPMVKCYETSMSEGLKHMVLRDRGL
HHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCC
AWLPLSMVHRELAQGVLCNAFPDHPRLSCCLPILLYKRRDSRRPAVERFWQAATACRLP
EECCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 7876157 [H]