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The map label for this gene is uup [H]

Identifier: 238919294

GI number: 238919294

Start: 1371283

End: 1373196

Strand: Direct

Name: uup [H]

Synonym: NT01EI_1384

Alternate gene names: 238919294

Gene position: 1371283-1373196 (Clockwise)

Preceding gene: 238919293

Following gene: 238919295

Centisome position: 35.97

GC content: 63.27

Gene sequence:

>1914_bases
ATGTCTTTGATTAGTCTTTCAGGCGCCTGGCTCTCTTTTAGCGATGCGCCGCTGCTGGATAATGCCGAGCTGCACATTGA
GCCCAACGAGCGCGTCTGTCTGGTCGGGCGCAACGGCGCGGGGAAATCGACCCTGCTGAAGATCTTGGGGCGCGAGCAGG
CGCTGGACGATGGGCGCGTCGTGTACGCCCAGGATTTGGTGGTGTCGCGTTTGCAGCAGGATCCGCCGCGTGATGTCGCC
GGTTCGGTATTCGACTTCGTGGCCGGTGGCGTGGCCGAGCAGGCACAGCATCTGCGCGACTACCATGAGCTGCTGCGTAA
GGTCGAGCGCGATCCCAGCGAGCAGCACCTGCGCCAGCTGGCGGAGCTGCAGGAGCGGCTGGAGCACCAGGGCATCTGGC
GGATGGATGCCCGCATTCGCGATGTGCTGACCAAGCTGGGGCTGGAGGCCGACAGTCCGCTTTCGGCGCTTTCCGGTGGC
TGGCTGCGCAAGGCGGCGCTGGCGCGTGCGCTGGTGTGCGAGCCGGACGTTCTGCTGCTGGATGAGCCGACCAACCACCT
GGATATCGATACCATTACCTGGCTGGAGGGATTCCTGAAGGAGTTTGGCGGCAGCATTATCTTCATCTCCCATGACCGCG
CCTTTATTCGTGCCATGGCGACGCGCATCGTCGACCTCGACCGCGGCAAGCTGGTCTCCTGGCCGGGAGACTATGACGCC
TATCTGACCGGTAAAGAGGAAGCGCTGCGGGTGGAAGAGCTGCAAAACGCCGAGTTCGACCGCCGACTGGCGCAGGAGGA
GGCGTGGATCCGTCAGGGGATCAAGGCGCGCCGTACCCGTAACGAGGGACGCGTGCGTGCGCTGAAGTCGATGCGTCAGG
AGCATGCCCAGCGCCGGGCGCAGCAGGGGAGCGCCAGGATGCAGGCCGAAGAGGCGCTGCGCTCCGGGAAAATCGTCTTC
GAGCTGGAGAACGTCAGCTACCACTGCGGCGATAAGACGCTGGTACGCGACTTTTCCGGTCAGGTGCTGCGCGGTGATAA
GATCGCTCTGGTCGGGGCCAACGGCTGCGGTAAAACGACGCTGCTGAAACTGATGCTTGGTCAGCTGAATCCGGACAGCG
GCAGCGTGCGCTGCGGCACCAAGCTGGAGATCGCCTATTTTGATCAGCACCGCGCCGAGCTGGATCCGGACAGGACAGTG
ATGGATAACCTGGCCGAGGGCAAGCAGGAGGTGATGGTCAACGGGCGCGCCCGGCATGTGCTGGGCTATCTGCAGGATTT
CCTGTTCCATCCCAAGCGGGCGATGACGCCGGTGCGCGCGCTCTCCGGCGGGGAGCGTAACCGACTGTTGTTGGCGAGAC
TGTTCCTAAAACCGAGCAATTTACTGGTGCTCGATGAACCTACCAACGATTTGGATATCGAAACGCTGGAGCTGCTGGAG
GAGCTGGTCGCCAACTACCCGGGAACCGTGCTGCTGGTGAGCCACGATCGTCAGTTTGTCGATAACTGTGTGACCGACTG
CTGGATCTTCGAGGGCGATGGCGTGATTGCCCGCTATACCGGCGGCTACGCCGATGCCCATCAGCAGCAGGCGGCCTCGC
AGGCGCTGCGTCAGCCGACGGCGACGGATGCCGCACCGCAGGCGCAGAAGGCCGAGGCGAAAACAGAGCGGCGTCGCAGC
AGCAATAAGCTGAGCTACAATCAGTTAAGGGAGCTGGAACAGCTGCCGCAGCAGATTGAGGCGCAGGAGGAGCAGCTCGC
CGCCCTGCAGGCGCAGGTCGCCTCACCGGACTTCTTCTCCCTGCCACACGGGGAGACCCAGCCGGTGCTGCAGGCGCTGG
CGGAGTGTGAGCAGACGCTGGAACAGGCGTATGCCCGCTGGGAATCCCTCGAAACGCAAAAAAATGCCAGCTGA

Upstream 100 bases:

>100_bases
CAGGAGATCACCGATCGCACGCTCTCTGCCGACTTTGCCCGTAACCGCCAGATCCACAATTGCTGGCTGGTGACCCACGC
CGGCGAGGAGCAGTAATTCC

Downstream 100 bases:

>100_bases
TTGAGGCTATAGTCGCAGGGATCATCATCTGCCTGATGGCTGCCGGCGTGCAGCGTATCAGGCTTTTTTATAACCGGATA
ATCTAATGTGCAGTCAACAG

Product: ABC transporter ATPase component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 637; Mature: 636

Protein sequence:

>637_residues
MSLISLSGAWLSFSDAPLLDNAELHIEPNERVCLVGRNGAGKSTLLKILGREQALDDGRVVYAQDLVVSRLQQDPPRDVA
GSVFDFVAGGVAEQAQHLRDYHELLRKVERDPSEQHLRQLAELQERLEHQGIWRMDARIRDVLTKLGLEADSPLSALSGG
WLRKAALARALVCEPDVLLLDEPTNHLDIDTITWLEGFLKEFGGSIIFISHDRAFIRAMATRIVDLDRGKLVSWPGDYDA
YLTGKEEALRVEELQNAEFDRRLAQEEAWIRQGIKARRTRNEGRVRALKSMRQEHAQRRAQQGSARMQAEEALRSGKIVF
ELENVSYHCGDKTLVRDFSGQVLRGDKIALVGANGCGKTTLLKLMLGQLNPDSGSVRCGTKLEIAYFDQHRAELDPDRTV
MDNLAEGKQEVMVNGRARHVLGYLQDFLFHPKRAMTPVRALSGGERNRLLLARLFLKPSNLLVLDEPTNDLDIETLELLE
ELVANYPGTVLLVSHDRQFVDNCVTDCWIFEGDGVIARYTGGYADAHQQQAASQALRQPTATDAAPQAQKAEAKTERRRS
SNKLSYNQLRELEQLPQQIEAQEEQLAALQAQVASPDFFSLPHGETQPVLQALAECEQTLEQAYARWESLETQKNAS

Sequences:

>Translated_637_residues
MSLISLSGAWLSFSDAPLLDNAELHIEPNERVCLVGRNGAGKSTLLKILGREQALDDGRVVYAQDLVVSRLQQDPPRDVA
GSVFDFVAGGVAEQAQHLRDYHELLRKVERDPSEQHLRQLAELQERLEHQGIWRMDARIRDVLTKLGLEADSPLSALSGG
WLRKAALARALVCEPDVLLLDEPTNHLDIDTITWLEGFLKEFGGSIIFISHDRAFIRAMATRIVDLDRGKLVSWPGDYDA
YLTGKEEALRVEELQNAEFDRRLAQEEAWIRQGIKARRTRNEGRVRALKSMRQEHAQRRAQQGSARMQAEEALRSGKIVF
ELENVSYHCGDKTLVRDFSGQVLRGDKIALVGANGCGKTTLLKLMLGQLNPDSGSVRCGTKLEIAYFDQHRAELDPDRTV
MDNLAEGKQEVMVNGRARHVLGYLQDFLFHPKRAMTPVRALSGGERNRLLLARLFLKPSNLLVLDEPTNDLDIETLELLE
ELVANYPGTVLLVSHDRQFVDNCVTDCWIFEGDGVIARYTGGYADAHQQQAASQALRQPTATDAAPQAQKAEAKTERRRS
SNKLSYNQLRELEQLPQQIEAQEEQLAALQAQVASPDFFSLPHGETQPVLQALAECEQTLEQAYARWESLETQKNAS
>Mature_636_residues
SLISLSGAWLSFSDAPLLDNAELHIEPNERVCLVGRNGAGKSTLLKILGREQALDDGRVVYAQDLVVSRLQQDPPRDVAG
SVFDFVAGGVAEQAQHLRDYHELLRKVERDPSEQHLRQLAELQERLEHQGIWRMDARIRDVLTKLGLEADSPLSALSGGW
LRKAALARALVCEPDVLLLDEPTNHLDIDTITWLEGFLKEFGGSIIFISHDRAFIRAMATRIVDLDRGKLVSWPGDYDAY
LTGKEEALRVEELQNAEFDRRLAQEEAWIRQGIKARRTRNEGRVRALKSMRQEHAQRRAQQGSARMQAEEALRSGKIVFE
LENVSYHCGDKTLVRDFSGQVLRGDKIALVGANGCGKTTLLKLMLGQLNPDSGSVRCGTKLEIAYFDQHRAELDPDRTVM
DNLAEGKQEVMVNGRARHVLGYLQDFLFHPKRAMTPVRALSGGERNRLLLARLFLKPSNLLVLDEPTNDLDIETLELLEE
LVANYPGTVLLVSHDRQFVDNCVTDCWIFEGDGVIARYTGGYADAHQQQAASQALRQPTATDAAPQAQKAEAKTERRRSS
NKLSYNQLRELEQLPQQIEAQEEQLAALQAQVASPDFFSLPHGETQPVLQALAECEQTLEQAYARWESLETQKNAS

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=541, Percent_Identity=33.826247689464, Blast_Score=223, Evalue=3e-58,
Organism=Homo sapiens, GI10947137, Length=538, Percent_Identity=30.4832713754647, Blast_Score=196, Evalue=4e-50,
Organism=Homo sapiens, GI27881506, Length=538, Percent_Identity=30.4832713754647, Blast_Score=196, Evalue=6e-50,
Organism=Homo sapiens, GI10947135, Length=549, Percent_Identity=29.143897996357, Blast_Score=172, Evalue=1e-42,
Organism=Homo sapiens, GI69354671, Length=549, Percent_Identity=28.9617486338798, Blast_Score=171, Evalue=2e-42,
Organism=Escherichia coli, GI1787182, Length=636, Percent_Identity=72.6415094339623, Blast_Score=918, Evalue=0.0,
Organism=Escherichia coli, GI2367384, Length=519, Percent_Identity=33.3333333333333, Blast_Score=290, Evalue=2e-79,
Organism=Escherichia coli, GI1787041, Length=527, Percent_Identity=33.2068311195446, Blast_Score=273, Evalue=3e-74,
Organism=Escherichia coli, GI1789751, Length=630, Percent_Identity=29.8412698412698, Blast_Score=265, Evalue=6e-72,
Organism=Escherichia coli, GI1788165, Length=191, Percent_Identity=34.5549738219895, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1787029, Length=241, Percent_Identity=28.6307053941909, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1789891, Length=276, Percent_Identity=28.9855072463768, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1788225, Length=242, Percent_Identity=25.2066115702479, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI87081791, Length=204, Percent_Identity=31.8627450980392, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1787164, Length=184, Percent_Identity=32.6086956521739, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787758, Length=170, Percent_Identity=31.7647058823529, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1787089, Length=254, Percent_Identity=27.1653543307087, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1786319, Length=223, Percent_Identity=31.8385650224215, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1790467, Length=236, Percent_Identity=25.4237288135593, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788761, Length=241, Percent_Identity=27.3858921161826, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1787500, Length=248, Percent_Identity=25.8064516129032, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI87081709, Length=235, Percent_Identity=28.5106382978723, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1789962, Length=228, Percent_Identity=26.7543859649123, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI87081834, Length=222, Percent_Identity=27.4774774774775, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1786398, Length=228, Percent_Identity=27.6315789473684, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1788644, Length=110, Percent_Identity=34.5454545454545, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1787712, Length=192, Percent_Identity=29.6875, Blast_Score=63, Evalue=6e-11,
Organism=Escherichia coli, GI1786975, Length=229, Percent_Identity=28.3842794759825, Blast_Score=63, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17559834, Length=530, Percent_Identity=29.622641509434, Blast_Score=227, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI17555318, Length=522, Percent_Identity=27.2030651340996, Blast_Score=197, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17553372, Length=543, Percent_Identity=30.7550644567219, Blast_Score=186, Evalue=3e-47,
Organism=Saccharomyces cerevisiae, GI6321121, Length=537, Percent_Identity=30.5400372439479, Blast_Score=221, Evalue=3e-58,
Organism=Saccharomyces cerevisiae, GI6320874, Length=545, Percent_Identity=29.5412844036697, Blast_Score=206, Evalue=7e-54,
Organism=Saccharomyces cerevisiae, GI6323278, Length=395, Percent_Identity=26.3291139240506, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6324314, Length=387, Percent_Identity=25.5813953488372, Blast_Score=119, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6325030, Length=384, Percent_Identity=26.8229166666667, Blast_Score=118, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6322640, Length=184, Percent_Identity=26.0869565217391, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24642252, Length=538, Percent_Identity=29.9256505576208, Blast_Score=215, Evalue=7e-56,
Organism=Drosophila melanogaster, GI18859989, Length=538, Percent_Identity=29.9256505576208, Blast_Score=215, Evalue=7e-56,
Organism=Drosophila melanogaster, GI24666836, Length=537, Percent_Identity=30.7262569832402, Blast_Score=214, Evalue=1e-55,
Organism=Drosophila melanogaster, GI24641342, Length=546, Percent_Identity=29.3040293040293, Blast_Score=200, Evalue=2e-51,
Organism=Drosophila melanogaster, GI116007184, Length=152, Percent_Identity=30.9210526315789, Blast_Score=71, Evalue=3e-12,
Organism=Drosophila melanogaster, GI221500365, Length=152, Percent_Identity=30.9210526315789, Blast_Score=71, Evalue=3e-12,
Organism=Drosophila melanogaster, GI281363262, Length=217, Percent_Identity=25.8064516129032, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24653245, Length=217, Percent_Identity=25.8064516129032, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI17136662, Length=232, Percent_Identity=24.1379310344828, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 71417; Mature: 71285

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLISLSGAWLSFSDAPLLDNAELHIEPNERVCLVGRNGAGKSTLLKILGREQALDDGRV
CCEEEECCCEECCCCCCCCCCCEEEECCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCE
VYAQDLVVSRLQQDPPRDVAGSVFDFVAGGVAEQAQHLRDYHELLRKVERDPSEQHLRQL
EEHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AELQERLEHQGIWRMDARIRDVLTKLGLEADSPLSALSGGWLRKAALARALVCEPDVLLL
HHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHCCHHHHHHHHHHHHHCCCCEEEE
DEPTNHLDIDTITWLEGFLKEFGGSIIFISHDRAFIRAMATRIVDLDRGKLVSWPGDYDA
ECCCCCCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCCCCEEECCCCCCC
YLTGKEEALRVEELQNAEFDRRLAQEEAWIRQGIKARRTRNEGRVRALKSMRQEHAQRRA
EECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHH
QQGSARMQAEEALRSGKIVFELENVSYHCGDKTLVRDFSGQVLRGDKIALVGANGCGKTT
HHCHHHHHHHHHHHCCCEEEEEECCEEECCCHHHHHHCCCCEEECCEEEEEECCCCCHHH
LLKLMLGQLNPDSGSVRCGTKLEIAYFDQHRAELDPDRTVMDNLAEGKQEVMVNGRARHV
HHHHHHHCCCCCCCCEECCCEEEEEEECCHHCCCCCCHHHHHHHHCCCHHHHHCCHHHHH
LGYLQDFLFHPKRAMTPVRALSGGERNRLLLARLFLKPSNLLVLDEPTNDLDIETLELLE
HHHHHHHHHCCHHHCCHHHHHCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHH
ELVANYPGTVLLVSHDRQFVDNCVTDCWIFEGDGVIARYTGGYADAHQQQAASQALRQPT
HHHHCCCCEEEEEECCHHHHHHHHHHCEEECCCCEEEEECCCCCHHHHHHHHHHHHHCCC
ATDAAPQAQKAEAKTERRRSSNKLSYNQLRELEQLPQQIEAQEEQLAALQAQVASPDFFS
CCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LPHGETQPVLQALAECEQTLEQAYARWESLETQKNAS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLISLSGAWLSFSDAPLLDNAELHIEPNERVCLVGRNGAGKSTLLKILGREQALDDGRV
CEEEECCCEECCCCCCCCCCCEEEECCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCE
VYAQDLVVSRLQQDPPRDVAGSVFDFVAGGVAEQAQHLRDYHELLRKVERDPSEQHLRQL
EEHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AELQERLEHQGIWRMDARIRDVLTKLGLEADSPLSALSGGWLRKAALARALVCEPDVLLL
HHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHCCHHHHHHHHHHHHHCCCCEEEE
DEPTNHLDIDTITWLEGFLKEFGGSIIFISHDRAFIRAMATRIVDLDRGKLVSWPGDYDA
ECCCCCCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCCCCEEECCCCCCC
YLTGKEEALRVEELQNAEFDRRLAQEEAWIRQGIKARRTRNEGRVRALKSMRQEHAQRRA
EECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHH
QQGSARMQAEEALRSGKIVFELENVSYHCGDKTLVRDFSGQVLRGDKIALVGANGCGKTT
HHCHHHHHHHHHHHCCCEEEEEECCEEECCCHHHHHHCCCCEEECCEEEEEECCCCCHHH
LLKLMLGQLNPDSGSVRCGTKLEIAYFDQHRAELDPDRTVMDNLAEGKQEVMVNGRARHV
HHHHHHHCCCCCCCCEECCCEEEEEEECCHHCCCCCCHHHHHHHHCCCHHHHHCCHHHHH
LGYLQDFLFHPKRAMTPVRALSGGERNRLLLARLFLKPSNLLVLDEPTNDLDIETLELLE
HHHHHHHHHCCHHHCCHHHHHCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHH
ELVANYPGTVLLVSHDRQFVDNCVTDCWIFEGDGVIARYTGGYADAHQQQAASQALRQPT
HHHHCCCCEEEEEECCHHHHHHHHHHCEEECCCCEEEEECCCCCHHHHHHHHHHHHHCCC
ATDAAPQAQKAEAKTERRRSSNKLSYNQLRELEQLPQQIEAQEEQLAALQAQVASPDFFS
CCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LPHGETQPVLQALAECEQTLEQAYARWESLETQKNAS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Endonuclease; Excision [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 9139905; 7751275 [H]