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The map label for this gene is lpxD [C]

Identifier: 238919246

GI number: 238919246

Start: 1323747

End: 1324214

Strand: Direct

Name: lpxD [C]

Synonym: NT01EI_1335

Alternate gene names: 238919246

Gene position: 1323747-1324214 (Clockwise)

Preceding gene: 238919244

Following gene: 238919250

Centisome position: 34.72

GC content: 49.57

Gene sequence:

>468_bases
ATGTTGAAAACGGCTATGAAATTGATTGACAGTGAAGTTCGGGATGTAATTTCAGGGGAAAACGTCACCATCGTCCAACC
TGCCAATATTTATGCCTGTGAACTCAGGGACAACGTGTTTGTCGGCCCCTTCGTTGAGATACAGAAAGGCTGTGTCATTG
GCAGTGGAAGCCGGATCCAGTCGCACACCTTTATCTGTGAAAACGTAACACTGGGTGAGAACTGCTTCATTGGCCATAAC
GTGACGTTCGCCAACGATCTGTTCCGGTCTGGAGCGCCGGACCCGTCACCGGATAACTGGATCACCATCTCCCTGGGGGA
TTCGGTTACTGTGGGCAGCGGCTCTACCATTCTATCAACATATATATGCAGTGGCTCCGTTATTGGTGCGGGTTCAGTTG
TGGTGAGGCCGATTGAGATCAAAGGCATTTATGCAGGAAATCCGGCAAGGCTGATCAGAACATTATGA

Upstream 100 bases:

>100_bases
GCACCTGCTCCCGCGCGCCCAGTACGAACGCTGTCTGAAGAGGTGGCATCTGATAAAAAAACCTTAACGTACACCAATTA
TCTTCTCTTAATGAGACCCT

Downstream 100 bases:

>100_bases
AAGTAAAAGGGCGATTATCGGCCCTTTTTATCAGCGGTAGATCGGTGAGTACGGCGGGTGAACAGAAAGCGACAGCCGGG
GATCGGCTTTTACCGCGGCT

Product: acetyltransferase

Products: UDP-2,3-Bis(3-Hydroxytetradecanoyl)Glucosamine; [Acyl-Carrier Protein]. [C]

Alternate protein names: Hexapaptide Repeat-Containing Transferase; UDP-3-O-(3-Hydroxymyristoyl)-Glucosamine N-Acyltransferase; Transferase Hexapeptide Repeat Containing Protein; Acyltransferase; Acetyltransferase Protein; Hexapeptide Repeat-Containing Acetyltransferase; Hexapeptide Repeat Acetyltransferase

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MLKTAMKLIDSEVRDVISGENVTIVQPANIYACELRDNVFVGPFVEIQKGCVIGSGSRIQSHTFICENVTLGENCFIGHN
VTFANDLFRSGAPDPSPDNWITISLGDSVTVGSGSTILSTYICSGSVIGAGSVVVRPIEIKGIYAGNPARLIRTL

Sequences:

>Translated_155_residues
MLKTAMKLIDSEVRDVISGENVTIVQPANIYACELRDNVFVGPFVEIQKGCVIGSGSRIQSHTFICENVTLGENCFIGHN
VTFANDLFRSGAPDPSPDNWITISLGDSVTVGSGSTILSTYICSGSVIGAGSVVVRPIEIKGIYAGNPARLIRTL
>Mature_155_residues
MLKTAMKLIDSEVRDVISGENVTIVQPANIYACELRDNVFVGPFVEIQKGCVIGSGSRIQSHTFICENVTLGENCFIGHN
VTFANDLFRSGAPDPSPDNWITISLGDSVTVGSGSTILSTYICSGSVIGAGSVVVRPIEIKGIYAGNPARLIRTL

Specific function: Lipid A biosynthesis; third step. [C]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.3.1.- [C]

Molecular weight: Translated: 16476; Mature: 16476

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKTAMKLIDSEVRDVISGENVTIVQPANIYACELRDNVFVGPFVEIQKGCVIGSGSRIQ
CCHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCEEECCCEEEECCEEEECCCCEE
SHTFICENVTLGENCFIGHNVTFANDLFRSGAPDPSPDNWITISLGDSVTVGSGSTILST
CCEEEECCCEECCCEEEECCCCHHHHHHHCCCCCCCCCCEEEEEECCEEEECCCCCEEEE
YICSGSVIGAGSVVVRPIEIKGIYAGNPARLIRTL
EEECCCEECCCCEEEEEEEEEEEEECCHHHHEECC
>Mature Secondary Structure
MLKTAMKLIDSEVRDVISGENVTIVQPANIYACELRDNVFVGPFVEIQKGCVIGSGSRIQ
CCHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCEEECCCEEEECCEEEECCCCEE
SHTFICENVTLGENCFIGHNVTFANDLFRSGAPDPSPDNWITISLGDSVTVGSGSTILST
CCEEEECCCEECCCEEEECCCCHHHHHHHCCCCCCCCCCEEEEEECCEEEECCCCCEEEE
YICSGSVIGAGSVVVRPIEIKGIYAGNPARLIRTL
EEECCCEECCCCEEEEEEEEEEEEECCHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-3-O-(3-Hydroxytetradecanoyl)Glucosamine; (R)-3-Hydroxytetradecanoyl-[Acyl-Carrier Protein] [C]

Specific reaction: UDP-3-O-(3-Hydroxytetradecanoyl)Glucosamine + (R)-3-Hydroxytetradecanoyl-[Acyl-Carrier Protein] = UDP-2,3-Bis(3-Hydroxytetradecanoyl)Glucosamine + [Acyl-Carrier Protein]. [C]

General reaction: Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA