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The map label for this gene is ugd [H]

Identifier: 238919229

GI number: 238919229

Start: 1303155

End: 1304321

Strand: Direct

Name: ugd [H]

Synonym: NT01EI_1312

Alternate gene names: 238919229

Gene position: 1303155-1304321 (Clockwise)

Preceding gene: 238919228

Following gene: 238919230

Centisome position: 34.18

GC content: 56.64

Gene sequence:

>1167_bases
ATGAAGATAGCGATTAGCGGTACGGGCTACGTCGGCCTGTCCAATGGAATTTTGCTGGCTCAGCATCATGAGGTGGTGGC
GCTGGATATTGTGGCGGAAAAGGTCGGGATGCTTAACCGGCGTCAGTCACCGATCGTGGATAAGGAGATCCAGGAGTACC
TCACTAACCGCTCCCTGAATTTCCGCGCGACGCTGGACAAGGAAGAGGCGTACCGCGGCGCTGATTTTGTCATTATCGCG
ACGCCGACCGACTATGATCCCAAGAGTAATTACTTTAACACCGCCAGCGTAGAGGCGGTGATCCGCGATGTGCTGGCGAT
TAACCCGGCGGCGGTGATGATCATCAAGTCGACCATTCCCGTCGGATTCACCCGGCAGCTGCGTGAGCGCCTGGGTATCG
ATAACCTGATCTTTTCGCCGGAGTTTCTGCGCGAGGGGCGGGCGCTGTATGACAACCTGTATCCGTCGCGTATCGTGGTC
GGCGAGCGCTCTGAGCGCGCGGAGCGCTTTGCTGCGCTGCTGCAGGAGGGGGCGATTAAACAGAATATCCCGACTCTGCT
GACCGATTCGACGGAGGCGGAGGCGATCAAGCTGTTTGCCAACACCTATCTGGCGATGCGGGTTGCCTATTTTAACGAGC
TGGATAGCTATGCCGAGGCACTGGGACTCAACAGCCGCCAGATCATTGAGGGGGTCAGCCTCGACCCGCGCATCGGTAAC
CACTATAACAATCCCTCGTTTGGCTATGGCGGCTACTGCCTGCCAAAGGATACCAAGCAGCTCCTGGCCAACTACTCCTC
GGTGCCCAATAACCTGATCCAGGCGATTGTCGAGGCCAACCGTACACGTAAAGACTTTATCGCCGACTCGATTATCGCGC
GCAATCCGCAGGTGGTGGGCGTGTACCGGCTGATTATGAAGAGCGGTTCGGATAACTTCCGCGCCTCCTCGATTCAGGGG
ATCATGAAGCGCATCAAGGCTAAGGGGATCAAGGTCGTGATCTTTGAGCCGGTGATGAAAGAGGACAGCTTCTTCCGCTC
AGAGGTGATCCGTGATCTGGAGCAGTTTAAGGCGATATCGGACGTGATCATCTCTAACCGTATGGCGCCGGAGCTGGATG
ACGTGGCGGATAAGGTCTACACCCGCGATATCTCCGGCAATGACTAA

Upstream 100 bases:

>100_bases
CGCAGTATGGTCTGGAGGCGATGATGACCGATACCTGGCGCTGGCAGCAGAACAACCCGAATGGATACCAGGATTAATTT
TATTAACACAAAGGTATGTG

Downstream 100 bases:

>100_bases
CCATTACCGGCAAATTTTGTAAGACAAAATTGGCCACTGAGGTTAGCATAATGTCCATTGGATCATACTGACCAACACCT
GCCTCCAACGCACGCCCCAG

Product: udp-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MKIAISGTGYVGLSNGILLAQHHEVVALDIVAEKVGMLNRRQSPIVDKEIQEYLTNRSLNFRATLDKEEAYRGADFVIIA
TPTDYDPKSNYFNTASVEAVIRDVLAINPAAVMIIKSTIPVGFTRQLRERLGIDNLIFSPEFLREGRALYDNLYPSRIVV
GERSERAERFAALLQEGAIKQNIPTLLTDSTEAEAIKLFANTYLAMRVAYFNELDSYAEALGLNSRQIIEGVSLDPRIGN
HYNNPSFGYGGYCLPKDTKQLLANYSSVPNNLIQAIVEANRTRKDFIADSIIARNPQVVGVYRLIMKSGSDNFRASSIQG
IMKRIKAKGIKVVIFEPVMKEDSFFRSEVIRDLEQFKAISDVIISNRMAPELDDVADKVYTRDISGND

Sequences:

>Translated_388_residues
MKIAISGTGYVGLSNGILLAQHHEVVALDIVAEKVGMLNRRQSPIVDKEIQEYLTNRSLNFRATLDKEEAYRGADFVIIA
TPTDYDPKSNYFNTASVEAVIRDVLAINPAAVMIIKSTIPVGFTRQLRERLGIDNLIFSPEFLREGRALYDNLYPSRIVV
GERSERAERFAALLQEGAIKQNIPTLLTDSTEAEAIKLFANTYLAMRVAYFNELDSYAEALGLNSRQIIEGVSLDPRIGN
HYNNPSFGYGGYCLPKDTKQLLANYSSVPNNLIQAIVEANRTRKDFIADSIIARNPQVVGVYRLIMKSGSDNFRASSIQG
IMKRIKAKGIKVVIFEPVMKEDSFFRSEVIRDLEQFKAISDVIISNRMAPELDDVADKVYTRDISGND
>Mature_388_residues
MKIAISGTGYVGLSNGILLAQHHEVVALDIVAEKVGMLNRRQSPIVDKEIQEYLTNRSLNFRATLDKEEAYRGADFVIIA
TPTDYDPKSNYFNTASVEAVIRDVLAINPAAVMIIKSTIPVGFTRQLRERLGIDNLIFSPEFLREGRALYDNLYPSRIVV
GERSERAERFAALLQEGAIKQNIPTLLTDSTEAEAIKLFANTYLAMRVAYFNELDSYAEALGLNSRQIIEGVSLDPRIGN
HYNNPSFGYGGYCLPKDTKQLLANYSSVPNNLIQAIVEANRTRKDFIADSIIARNPQVVGVYRLIMKSGSDNFRASSIQG
IMKRIKAKGIKVVIFEPVMKEDSFFRSEVIRDLEQFKAISDVIISNRMAPELDDVADKVYTRDISGND

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=386, Percent_Identity=25.3886010362694, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI296040438, Length=281, Percent_Identity=24.9110320284698, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI296040443, Length=235, Percent_Identity=25.531914893617, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1788340, Length=388, Percent_Identity=80.4123711340206, Blast_Score=653, Evalue=0.0,
Organism=Escherichia coli, GI48994968, Length=376, Percent_Identity=24.468085106383, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17560350, Length=393, Percent_Identity=26.7175572519084, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI17136908, Length=385, Percent_Identity=26.7532467532467, Blast_Score=111, Evalue=9e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 43387; Mature: 43387

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAISGTGYVGLSNGILLAQHHEVVALDIVAEKVGMLNRRQSPIVDKEIQEYLTNRSLN
CEEEEECCCEEECCCCEEEEECCCEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCE
FRATLDKEEAYRGADFVIIATPTDYDPKSNYFNTASVEAVIRDVLAINPAAVMIIKSTIP
EEEECCHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCC
VGFTRQLRERLGIDNLIFSPEFLREGRALYDNLYPSRIVVGERSERAERFAALLQEGAIK
CCHHHHHHHHCCCCCEEECHHHHHCCHHHHHCCCCCEEEECCCHHHHHHHHHHHHHCCHH
QNIPTLLTDSTEAEAIKLFANTYLAMRVAYFNELDSYAEALGLNSRQIIEGVSLDPRIGN
HCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCC
HYNNPSFGYGGYCLPKDTKQLLANYSSVPNNLIQAIVEANRTRKDFIADSIIARNPQVVG
CCCCCCCCCCCEECCHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHH
VYRLIMKSGSDNFRASSIQGIMKRIKAKGIKVVIFEPVMKEDSFFRSEVIRDLEQFKAIS
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEECCHHCCCHHHHHHHHHHHHHHHHHH
DVIISNRMAPELDDVADKVYTRDISGND
HHHHHCCCCCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKIAISGTGYVGLSNGILLAQHHEVVALDIVAEKVGMLNRRQSPIVDKEIQEYLTNRSLN
CEEEEECCCEEECCCCEEEEECCCEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCE
FRATLDKEEAYRGADFVIIATPTDYDPKSNYFNTASVEAVIRDVLAINPAAVMIIKSTIP
EEEECCHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCC
VGFTRQLRERLGIDNLIFSPEFLREGRALYDNLYPSRIVVGERSERAERFAALLQEGAIK
CCHHHHHHHHCCCCCEEECHHHHHCCHHHHHCCCCCEEEECCCHHHHHHHHHHHHHCCHH
QNIPTLLTDSTEAEAIKLFANTYLAMRVAYFNELDSYAEALGLNSRQIIEGVSLDPRIGN
HCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCC
HYNNPSFGYGGYCLPKDTKQLLANYSSVPNNLIQAIVEANRTRKDFIADSIIARNPQVVG
CCCCCCCCCCCEECCHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHH
VYRLIMKSGSDNFRASSIQGIMKRIKAKGIKVVIFEPVMKEDSFFRSEVIRDLEQFKAIS
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEECCHHCCCHHHHHHHHHHHHHHHHHH
DVIISNRMAPELDDVADKVYTRDISGND
HHHHHCCCCCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9383197 [H]