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The map label for this gene is dcuC [H]

Identifier: 238919217

GI number: 238919217

Start: 1291139

End: 1292497

Strand: Direct

Name: dcuC [H]

Synonym: NT01EI_1300

Alternate gene names: 238919217

Gene position: 1291139-1292497 (Clockwise)

Preceding gene: 238919216

Following gene: 238919219

Centisome position: 33.87

GC content: 60.34

Gene sequence:

>1359_bases
ATGCTTGAGCTACTGATTGGGGTCGTGGTTGCCGTTGGCGTCGGGCGTTACATTATTAAAGGATACTCCCCCACCGGGGT
ACTGATGACCGGCGGCCTGCTGCTGCTGATCATCAGCGCGCTGATGGGGCACGATGTCCTGCCCGCCAGCAGCAAGTCGA
CCGGCTGGCGCGCGACCGATATCGTTGAGTATGTAAAAGTTCTGCTGATGAGTCGCGGCGGCGACCTCGGCATGATGATC
ATGATGCTGTGCGGTTTTGCCGCCTATATGACCCATATCGGTGCCAACGATATGGTGGTCAAGCTGGCCTCCCGCCCGCT
GCGCTATATTAACTCGCCCTATATTTTAATGATTGCGGCCTACTTTGTCGCCTGCCTGATGTCGCTGGCCGTTTCGTCGG
CCACCGGGCTGGGAGTATTGCTGATGGCAACCCTGTTCCCGGTGATGGTCAACGTGGGGATCAGCCGGGGGGCGGCGGCG
GCGATCTGTGCCTCGCCTGCGGCGATCATCCTGGCTCCGACCTCCGGCGATGTGGTGCTGGCAGCCAAGGCGTCCGAAAT
GCCGCTGATCGACTTTGCCTTTAAAACAACCCTGCCCATCTCCATCATCGCTATCGTCTGTATGGCGATTGCCCACTACT
TCTGGCAGCGCTACCTGGACAACAAGGAGCAGGCGCAGCACGAGATACTGGACGTCAACGAGATCACCACCACGGCACCC
TCGTTTTATGCCATTCTGCCCTTTACGCCGATCATCGGCGTGCTGGTGTTCGACGGTAAGTGGGGGCCACATCTGCACAT
CATCAGCGTCCTGGTTATCTGTATGCTGCTGGCCTCGGTGACTGAGTTTTTGCGCAGCTTCGACGCTAAAAAGGTCTATA
GCGGGCTGGAGGTGGCCTACCGCGGGATGGCGGACGCCTTTGCCAGCGTGGTGATGCTGTTGGTGGCCGCCGGGGTCTTT
GCCCAGGGGCTGAGCACCGTCGGCTTTATCAGCAGCCTGATCGAGCTGGCCCAGTCCTTTGGCACCGGTGGCATCATCAT
GATGCTGGTGCTGGTGGTGATCACCATGCTGGCGGCGATGACCACCGGCTCCGGCAACGCGCCGTTCTACGCCTTTGTCG
AGTTGATCCCCAAGCTGTCCGGCCAGATGGGCATCAACCCGGCCTACCTGACCATTCCGATGCTGCAGGCCTCCAATCTG
GGCCGCACCCTATCGCCGGTTTCCGGTGTGGTGGTGGCTGTCTCCGGGATGGCCAAGATCTCCCCCTTTGAGGTGGTTAA
ACGCACCTCGGTGCCGGTGCTGGTCGGCCTGGTGGTGGTGATCGTCGCCACCGAGTTTATGGTACCGCTGCACCGCTGA

Upstream 100 bases:

>100_bases
AGTTTTGACCGTGTTAAAAGGAATTAACAGCTAATAAAGGCAGAAACAATGCCTGTCTTGGGTGCGGCTGAGGTCGCCTG
TCTATCTTTTGAGGAAGAAT

Downstream 100 bases:

>100_bases
CAAATGCAGCGATATACACGGAGAGGGCAGGCCAGAGGCCTGCCTTTTTTGGTTTGCGGTGGCAAGTGCCAGCCATGTGG
AAATGACATGTCGATAGGCT

Product: C4-dicarboxylate transporter DcuC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MLELLIGVVVAVGVGRYIIKGYSPTGVLMTGGLLLLIISALMGHDVLPASSKSTGWRATDIVEYVKVLLMSRGGDLGMMI
MMLCGFAAYMTHIGANDMVVKLASRPLRYINSPYILMIAAYFVACLMSLAVSSATGLGVLLMATLFPVMVNVGISRGAAA
AICASPAAIILAPTSGDVVLAAKASEMPLIDFAFKTTLPISIIAIVCMAIAHYFWQRYLDNKEQAQHEILDVNEITTTAP
SFYAILPFTPIIGVLVFDGKWGPHLHIISVLVICMLLASVTEFLRSFDAKKVYSGLEVAYRGMADAFASVVMLLVAAGVF
AQGLSTVGFISSLIELAQSFGTGGIIMMLVLVVITMLAAMTTGSGNAPFYAFVELIPKLSGQMGINPAYLTIPMLQASNL
GRTLSPVSGVVVAVSGMAKISPFEVVKRTSVPVLVGLVVVIVATEFMVPLHR

Sequences:

>Translated_452_residues
MLELLIGVVVAVGVGRYIIKGYSPTGVLMTGGLLLLIISALMGHDVLPASSKSTGWRATDIVEYVKVLLMSRGGDLGMMI
MMLCGFAAYMTHIGANDMVVKLASRPLRYINSPYILMIAAYFVACLMSLAVSSATGLGVLLMATLFPVMVNVGISRGAAA
AICASPAAIILAPTSGDVVLAAKASEMPLIDFAFKTTLPISIIAIVCMAIAHYFWQRYLDNKEQAQHEILDVNEITTTAP
SFYAILPFTPIIGVLVFDGKWGPHLHIISVLVICMLLASVTEFLRSFDAKKVYSGLEVAYRGMADAFASVVMLLVAAGVF
AQGLSTVGFISSLIELAQSFGTGGIIMMLVLVVITMLAAMTTGSGNAPFYAFVELIPKLSGQMGINPAYLTIPMLQASNL
GRTLSPVSGVVVAVSGMAKISPFEVVKRTSVPVLVGLVVVIVATEFMVPLHR
>Mature_452_residues
MLELLIGVVVAVGVGRYIIKGYSPTGVLMTGGLLLLIISALMGHDVLPASSKSTGWRATDIVEYVKVLLMSRGGDLGMMI
MMLCGFAAYMTHIGANDMVVKLASRPLRYINSPYILMIAAYFVACLMSLAVSSATGLGVLLMATLFPVMVNVGISRGAAA
AICASPAAIILAPTSGDVVLAAKASEMPLIDFAFKTTLPISIIAIVCMAIAHYFWQRYLDNKEQAQHEILDVNEITTTAP
SFYAILPFTPIIGVLVFDGKWGPHLHIISVLVICMLLASVTEFLRSFDAKKVYSGLEVAYRGMADAFASVVMLLVAAGVF
AQGLSTVGFISSLIELAQSFGTGGIIMMLVLVVITMLAAMTTGSGNAPFYAFVELIPKLSGQMGINPAYLTIPMLQASNL
GRTLSPVSGVVVAVSGMAKISPFEVVKRTSVPVLVGLVVVIVATEFMVPLHR

Specific function: Responsible for the transport of C4-dicarboxylates during anaerobic growth [H]

COG id: COG3069

COG function: function code C; C4-dicarboxylate transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dcuC/dcuD transporter (TC 2.A.61) family [H]

Homologues:

Organism=Escherichia coli, GI1786839, Length=434, Percent_Identity=86.4055299539171, Blast_Score=655, Evalue=0.0,
Organism=Escherichia coli, GI1789622, Length=450, Percent_Identity=35.7777777777778, Blast_Score=289, Evalue=3e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018385
- InterPro:   IPR004669 [H]

Pfam domain/function: PF03606 DcuC [H]

EC number: NA

Molecular weight: Translated: 47839; Mature: 47839

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
6.0 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
6.0 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLELLIGVVVAVGVGRYIIKGYSPTGVLMTGGLLLLIISALMGHDVLPASSKSTGWRATD
CHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
IVEYVKVLLMSRGGDLGMMIMMLCGFAAYMTHIGANDMVVKLASRPLRYINSPYILMIAA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHH
YFVACLMSLAVSSATGLGVLLMATLFPVMVNVGISRGAAAAICASPAAIILAPTSGDVVL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEECCCCCEEE
AAKASEMPLIDFAFKTTLPISIIAIVCMAIAHYFWQRYLDNKEQAQHEILDVNEITTTAP
EECCCCCCEEHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHHCCCC
SFYAILPFTPIIGVLVFDGKWGPHLHIISVLVICMLLASVTEFLRSFDAKKVYSGLEVAY
CCEEHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
RGMADAFASVVMLLVAAGVFAQGLSTVGFISSLIELAQSFGTGGIIMMLVLVVITMLAAM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
TTGSGNAPFYAFVELIPKLSGQMGINPAYLTIPMLQASNLGRTLSPVSGVVVAVSGMAKI
CCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEHHHHCCCCCCCCHHHHHHHHCCCCCCC
SPFEVVKRTSVPVLVGLVVVIVATEFMVPLHR
CHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLELLIGVVVAVGVGRYIIKGYSPTGVLMTGGLLLLIISALMGHDVLPASSKSTGWRATD
CHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
IVEYVKVLLMSRGGDLGMMIMMLCGFAAYMTHIGANDMVVKLASRPLRYINSPYILMIAA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHH
YFVACLMSLAVSSATGLGVLLMATLFPVMVNVGISRGAAAAICASPAAIILAPTSGDVVL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEECCCCCEEE
AAKASEMPLIDFAFKTTLPISIIAIVCMAIAHYFWQRYLDNKEQAQHEILDVNEITTTAP
EECCCCCCEEHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHHCCCC
SFYAILPFTPIIGVLVFDGKWGPHLHIISVLVICMLLASVTEFLRSFDAKKVYSGLEVAY
CCEEHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
RGMADAFASVVMLLVAAGVFAQGLSTVGFISSLIELAQSFGTGGIIMMLVLVVITMLAAM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
TTGSGNAPFYAFVELIPKLSGQMGINPAYLTIPMLQASNLGRTLSPVSGVVVAVSGMAKI
CCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEHHHHCCCCCCCCHHHHHHHHCCCCCCC
SPFEVVKRTSVPVLVGLVVVIVATEFMVPLHR
CHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]