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The map label for this gene is tmcA [H]

Identifier: 238919132

GI number: 238919132

Start: 1196713

End: 1198674

Strand: Direct

Name: tmcA [H]

Synonym: NT01EI_1203

Alternate gene names: 238919132

Gene position: 1196713-1198674 (Clockwise)

Preceding gene: 238919131

Following gene: 238919133

Centisome position: 31.39

GC content: 70.54

Gene sequence:

>1962_bases
ATGCCGCTTTCTGTCTCTCTTCCTGCCATGTCCCGCGCCGGTGTGCGCCGCCTGCTGGTGATCAGCGGCGAGGCCGACTG
GTGCCGACGGCGCGCCGCCCTTGCCATCGCCCCGCTGGGCGATGTGACCTGGTGCGGCAGCCCGGCGCCGACGGGATGTC
AGATGCTGTCGCTGGCGCAGATCCGGACGGTGCTGGGACGTGAGTTGGGGCACTGCGTGCTGGATTGGCATCCGGGCTGT
CACGCGGAGGTGCTGGCGGCGTTGGCCGGTACGCTGCGTGCCGGCAGCTGGCTGATCCTGCTGACGCCGCCGTGGTCTGC
CTGGGCGAAGCGTCCCGATGATGACAGCCTGCGCTGGAGCGAGCGCGAACATCCCATCGCCACGGCGAATTTTGTTCACC
ATCTGCAGCGGACGCTGTCCGACGCCGACGGCGTCACGCTGTGGCGCCAGGGGGAGGTGTGCCCGGCGCCAATGCCGCTG
GGGTGTTCGGCGTGGCGGGCACCGGATGGCGCGCCGACGGTGCAGCAGCAGGCGATACTGCGCGCACTGCGTACGCCGGC
CGCCGTCAATGTGGTGCTGGGTCCCCGCGGGCGTGGCAAGTCAACCCTGAGCGGCATGCTGGCCGCCGAGCTGCGCGGTG
ACTGTCTGCTGACGGCGCCGGCCCGGGTCGCCGCCGAACGGGTACAGACGACGGCGGGCACGCTGCCGTTCGTGGCGCCC
GATCTGCTGCTGCAGCGGATCGAGGCCGGGGAGGCGCTGCCCGGCTGGCTGCTGATCGATGAGGCGGCGGCGATTCCGGC
GCCGCTGCTGCAGCGCCTGATTGTGGCGTTTCCCCATGTGCTGATGACCACCACGGTACAGGGCTACGAGGGGACCGGTC
GCGGGTTTCTGCTCAAGTTCTGCGCAGCACTGCCCGATTGTCGTATCCATAGCCTCGATCGGCCGCTGCGCTGGGCCAGC
GGCGATCCGCTGGAAGCATGGCTGAACGCCGCGCTGCTGTTCAGCGATACCTGTGGAGCGGTGGCGCCGGTCAGCGCGCT
GCGCTGGCTGGATCAGCGTCAGTGGCAGACGGCACCGGTGCTGATGGCGGCCTTTTATGCCCTGCTGACCAGCGCCCACT
ACCGGACATCGCCGCTCGATCTGCGGCGCCTGATGGATGCGCCTGGTCAGCGTCTGTGCGCGGCGCTGGGCGAGGCACGG
GTGCAGGGGGCGCTGTGGCTGGTGGAAGAGGGGGGACTGTCTGCTGCGCTGGCGCAGGCGGTATGGGCCGGTGAGCGTCG
TCCGCGTGGTAGCCTGGTCGCCCAGTCGCTGGCGGCGCACGGCGGTGAGCCCTGCGCCCCACGGTTGCGATCCTGGCGCG
TCAGCCGCATCGCCGTGATGCCGGCGCTGCGACGCCGTGGTGTGGCGTCAGCGTTGATAGCCGAGGCGCTGACGCAGGCG
CGGGCGGGGGCGATGGACTTTGTTTCGGTCAGCTTTGGCTATACCGGTGCGCTCTGGGCGTTCTGGCAACGTTGCGGATT
TACCCTGGTGCGCGTGGGGACTCAGAGAGAGGCCAGCAGCGGCTGCTATACGGCGATGGCACTCTGTCCGCTGACGGCGG
CGGGAGAGGCACTGACCCGGCGTTTGGCCCGGCGTCTGGCGCGGGATGCCCGCTGGCTGATGGCGCAGACCGGGCTTACG
CTCCCGCTGACGCCGCTGGTTGCGGCCGGGCCCGATGAGGCCGATCTGCGTGAGTTGGACGGTTTTGCCCATCATGCCCG
TCCCTACGATAGCGCCTGTCCGGCGCTGCTGCGTTTTCTGACCTGCCGACGGACCTCTGCGCTGCCGCCGCTGCTGGCGC
AGCTGTTGCAGGTGCAGGGCGATCTGGCACGGCTGCCGCCGCAGGGGGGCATCAGCGGACGGCGGGCCCTGATCGCCGCC
CTGCGCCGGGCGCTGGCCGCCGCGCTGACGACGACGGCGTAA

Upstream 100 bases:

>100_bases
AGATATTTTTGTGGCCGTTTGTTAATGACGGCGTGCGGCAGCGCTGACGGCGGCGATACTGGTATACTCTGTGATCCCCT
TCTTCTGCCGTGGTGTCGCT

Downstream 100 bases:

>100_bases
CGCCGTCGGCACACCCGGCCGGGAGGCGCGCGGACAGCGTGGCTTTTCTCCTGGCGCAGCAGGCGTATAGTAGGAAACAA
GAGCATCCGCATGAGTGATT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 653; Mature: 652

Protein sequence:

>653_residues
MPLSVSLPAMSRAGVRRLLVISGEADWCRRRAALAIAPLGDVTWCGSPAPTGCQMLSLAQIRTVLGRELGHCVLDWHPGC
HAEVLAALAGTLRAGSWLILLTPPWSAWAKRPDDDSLRWSEREHPIATANFVHHLQRTLSDADGVTLWRQGEVCPAPMPL
GCSAWRAPDGAPTVQQQAILRALRTPAAVNVVLGPRGRGKSTLSGMLAAELRGDCLLTAPARVAAERVQTTAGTLPFVAP
DLLLQRIEAGEALPGWLLIDEAAAIPAPLLQRLIVAFPHVLMTTTVQGYEGTGRGFLLKFCAALPDCRIHSLDRPLRWAS
GDPLEAWLNAALLFSDTCGAVAPVSALRWLDQRQWQTAPVLMAAFYALLTSAHYRTSPLDLRRLMDAPGQRLCAALGEAR
VQGALWLVEEGGLSAALAQAVWAGERRPRGSLVAQSLAAHGGEPCAPRLRSWRVSRIAVMPALRRRGVASALIAEALTQA
RAGAMDFVSVSFGYTGALWAFWQRCGFTLVRVGTQREASSGCYTAMALCPLTAAGEALTRRLARRLARDARWLMAQTGLT
LPLTPLVAAGPDEADLRELDGFAHHARPYDSACPALLRFLTCRRTSALPPLLAQLLQVQGDLARLPPQGGISGRRALIAA
LRRALAAALTTTA

Sequences:

>Translated_653_residues
MPLSVSLPAMSRAGVRRLLVISGEADWCRRRAALAIAPLGDVTWCGSPAPTGCQMLSLAQIRTVLGRELGHCVLDWHPGC
HAEVLAALAGTLRAGSWLILLTPPWSAWAKRPDDDSLRWSEREHPIATANFVHHLQRTLSDADGVTLWRQGEVCPAPMPL
GCSAWRAPDGAPTVQQQAILRALRTPAAVNVVLGPRGRGKSTLSGMLAAELRGDCLLTAPARVAAERVQTTAGTLPFVAP
DLLLQRIEAGEALPGWLLIDEAAAIPAPLLQRLIVAFPHVLMTTTVQGYEGTGRGFLLKFCAALPDCRIHSLDRPLRWAS
GDPLEAWLNAALLFSDTCGAVAPVSALRWLDQRQWQTAPVLMAAFYALLTSAHYRTSPLDLRRLMDAPGQRLCAALGEAR
VQGALWLVEEGGLSAALAQAVWAGERRPRGSLVAQSLAAHGGEPCAPRLRSWRVSRIAVMPALRRRGVASALIAEALTQA
RAGAMDFVSVSFGYTGALWAFWQRCGFTLVRVGTQREASSGCYTAMALCPLTAAGEALTRRLARRLARDARWLMAQTGLT
LPLTPLVAAGPDEADLRELDGFAHHARPYDSACPALLRFLTCRRTSALPPLLAQLLQVQGDLARLPPQGGISGRRALIAA
LRRALAAALTTTA
>Mature_652_residues
PLSVSLPAMSRAGVRRLLVISGEADWCRRRAALAIAPLGDVTWCGSPAPTGCQMLSLAQIRTVLGRELGHCVLDWHPGCH
AEVLAALAGTLRAGSWLILLTPPWSAWAKRPDDDSLRWSEREHPIATANFVHHLQRTLSDADGVTLWRQGEVCPAPMPLG
CSAWRAPDGAPTVQQQAILRALRTPAAVNVVLGPRGRGKSTLSGMLAAELRGDCLLTAPARVAAERVQTTAGTLPFVAPD
LLLQRIEAGEALPGWLLIDEAAAIPAPLLQRLIVAFPHVLMTTTVQGYEGTGRGFLLKFCAALPDCRIHSLDRPLRWASG
DPLEAWLNAALLFSDTCGAVAPVSALRWLDQRQWQTAPVLMAAFYALLTSAHYRTSPLDLRRLMDAPGQRLCAALGEARV
QGALWLVEEGGLSAALAQAVWAGERRPRGSLVAQSLAAHGGEPCAPRLRSWRVSRIAVMPALRRRGVASALIAEALTQAR
AGAMDFVSVSFGYTGALWAFWQRCGFTLVRVGTQREASSGCYTAMALCPLTAAGEALTRRLARRLARDARWLMAQTGLTL
PLTPLVAAGPDEADLRELDGFAHHARPYDSACPALLRFLTCRRTSALPPLLAQLLQVQGDLARLPPQGGISGRRALIAAL
RRALAAALTTTA

Specific function: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) [H]

COG id: COG1444

COG function: function code R; Predicted P-loop ATPase fused to an acetyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1788818, Length=645, Percent_Identity=49.4573643410853, Blast_Score=541, Evalue=1e-155,
Organism=Caenorhabditis elegans, GI17507621, Length=415, Percent_Identity=23.855421686747, Blast_Score=84, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324197, Length=272, Percent_Identity=27.9411764705882, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24640662, Length=514, Percent_Identity=25.4863813229572, Blast_Score=95, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR013562
- InterPro:   IPR007807 [H]

Pfam domain/function: PF08351 DUF1726; PF05127 DUF699 [H]

EC number: NA

Molecular weight: Translated: 70040; Mature: 69909

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLSVSLPAMSRAGVRRLLVISGEADWCRRRAALAIAPLGDVTWCGSPAPTGCQMLSLAQ
CCCCCCCCCHHHCCCEEEEEEECCHHHHHHHHHEEEECCCCCCCCCCCCCCHHHHHHHHH
IRTVLGRELGHCVLDWHPGCHAEVLAALAGTLRAGSWLILLTPPWSAWAKRPDDDSLRWS
HHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHCCCCCCCCCCCC
EREHPIATANFVHHLQRTLSDADGVTLWRQGEVCPAPMPLGCSAWRAPDGAPTVQQQAIL
CCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
RALRTPAAVNVVLGPRGRGKSTLSGMLAAELRGDCLLTAPARVAAERVQTTAGTLPFVAP
HHHCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHCCCCCHHHH
DLLLQRIEAGEALPGWLLIDEAAAIPAPLLQRLIVAFPHVLMTTTVQGYEGTGRGFLLKF
HHHHHHHHCCCCCCCEEEECCHHCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHH
CAALPDCRIHSLDRPLRWASGDPLEAWLNAALLFSDTCGAVAPVSALRWLDQRQWQTAPV
HHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHH
LMAAFYALLTSAHYRTSPLDLRRLMDAPGQRLCAALGEARVQGALWLVEEGGLSAALAQA
HHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHH
VWAGERRPRGSLVAQSLAAHGGEPCAPRLRSWRVSRIAVMPALRRRGVASALIAEALTQA
HHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
RAGAMDFVSVSFGYTGALWAFWQRCGFTLVRVGTQREASSGCYTAMALCPLTAAGEALTR
HCCCCCEEEECCCCHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHHCCHHHHHHHHH
RLARRLARDARWLMAQTGLTLPLTPLVAAGPDEADLRELDGFAHHARPYDSACPALLRFL
HHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHH
TCRRTSALPPLLAQLLQVQGDLARLPPQGGISGRRALIAALRRALAAALTTTA
HHHHCCCCHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PLSVSLPAMSRAGVRRLLVISGEADWCRRRAALAIAPLGDVTWCGSPAPTGCQMLSLAQ
CCCCCCCCHHHCCCEEEEEEECCHHHHHHHHHEEEECCCCCCCCCCCCCCHHHHHHHHH
IRTVLGRELGHCVLDWHPGCHAEVLAALAGTLRAGSWLILLTPPWSAWAKRPDDDSLRWS
HHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHCCCCCCCCCCCC
EREHPIATANFVHHLQRTLSDADGVTLWRQGEVCPAPMPLGCSAWRAPDGAPTVQQQAIL
CCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
RALRTPAAVNVVLGPRGRGKSTLSGMLAAELRGDCLLTAPARVAAERVQTTAGTLPFVAP
HHHCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHCCCCCHHHH
DLLLQRIEAGEALPGWLLIDEAAAIPAPLLQRLIVAFPHVLMTTTVQGYEGTGRGFLLKF
HHHHHHHHCCCCCCCEEEECCHHCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHH
CAALPDCRIHSLDRPLRWASGDPLEAWLNAALLFSDTCGAVAPVSALRWLDQRQWQTAPV
HHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHH
LMAAFYALLTSAHYRTSPLDLRRLMDAPGQRLCAALGEARVQGALWLVEEGGLSAALAQA
HHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHH
VWAGERRPRGSLVAQSLAAHGGEPCAPRLRSWRVSRIAVMPALRRRGVASALIAEALTQA
HHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
RAGAMDFVSVSFGYTGALWAFWQRCGFTLVRVGTQREASSGCYTAMALCPLTAAGEALTR
HCCCCCEEEECCCCHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHHCCHHHHHHHHH
RLARRLARDARWLMAQTGLTLPLTPLVAAGPDEADLRELDGFAHHARPYDSACPALLRFL
HHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHH
TCRRTSALPPLLAQLLQVQGDLARLPPQGGISGRRALIAALRRALAAALTTTA
HHHHCCCCHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA