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The map label for this gene is ppiD [H]

Identifier: 238919016

GI number: 238919016

Start: 1079749

End: 1081629

Strand: Direct

Name: ppiD [H]

Synonym: NT01EI_1083

Alternate gene names: 238919016

Gene position: 1079749-1081629 (Clockwise)

Preceding gene: 238919015

Following gene: 238919017

Centisome position: 28.32

GC content: 57.52

Gene sequence:

>1881_bases
ATGATGGACAATTTACGCGCGGCCGCCAATCACGTCGTGCTCAAGGTTATCCTGGCTCTGATCATCATCTCGTTTGTGCT
GACCGGGGTAGGTAATTATCTGATCGGCGGATCCGGCGACTATGCGGCCAAGGTGGATGGCCAAGAGATCGGTCGGGCCC
AGCTCGAACAGGCTGTGCAGAATGAGCGCAGCCGTCTGCAACAGCAGCTGGGCGATCAGTTCTCCGTGCTGGCAGGTAAC
GAAGGATATATGAAAGAGCTGCGTAAGCAGGTGCTTTCCCGCATGATCGATGACGTGTTGCTCGATCAGTATGCCAAAAA
GCTTAATCTGGCGATCAGCGATGCACAGGTAAAGGAAGCGATCCGCGCAATGCCCTATTTCCAGAGCGATAATCACTTCG
ATAACGCTAAATATCTGGATATGGTGGCGCGTCTGGGACTGAGCCCGGATACCTACGCTCAGCTGGTGCGTCAGCAGCTG
GTGACCCAGCAGCTAATCCAGGGGTTCACCGCCACCGGCTTTACCCTGCCGGCTGAGGTCAACGCCTTGGCGGCGCTGAC
TATGCAGCAGCGTCAGGTCAGCCTGGCAACCATTGACATCAGCAAGCTGATGCCGCTGCAGCAGGTCAGCGATGCGGAGC
TACAGGGCTATTATCAGCAGCATCAGAGCAGCTTCATTGCCCCAGAGACGGTCAAGGTACGCTATATCGAAATGGATGCT
GCGGCCATCAACGATAAAATGACGGTCAGTAATGCGGAGATTAGCGCCTATTACGATCAGCATAAAGGGAGCTTTACCCA
ACCGGCGCGCAGTGACTACAGCGTGATCCAGGTGAAGACAGAGGCGGAGGCGAAGGCTATCGCCGGGCAGTTGGCCAGCG
GTGCCGATTTCGCGACCCTGGCCAAGGAGAAGTCTACCGATATTATCTCCCGTAAAAACGGCGGTGAACTGGGTTGGCTG
GAGCAGGAAACCACGCCGGATGAGATCCGCGCGGCTAAACTGAGCCATAAAGGTGACGTCTCTGCACCGATAGCCTCCAG
CGTGGGCTACCTGATCGTGCGTCTGAACGGTATACAGCCCGCGGTGGTTAAACCGTTGTCTGAGGTACGTGCAGAGATCG
CCGACAAGGTGAAGCAGCAGAAGGCGCTGGATGCCTTCTATGCGCTGCAGCAGAAGGTGAGCGATGCGGCGACCAACGAC
AATGATTCGCTGGCCGGGGCCGAAGATGCCGCCGGGGTGAAAGCGACGGAGACCGGCTGGTTTTCCCGCGACAGTGTGCC
ACAGGTACTTGATTTTAAACCGATTACCCAGGCTATCTTCGACGGTTCCCTGTTTGGGGAAAACGGCACGCCGGGCAGTA
ACTCTGATGTGATCAGCGTCGAGGGCGATCGCGCTTTTGTACTGCGCGTCAGTGAGCACAAGCCAGAGGCGGTGAAACCG
TTCGATCAGGTGCGCGATCAGGTGACGGAGCTGCTGAAGCGTCAGAAGGCGATTGCCCAGGCGCGCAGTGATGGCGAGAA
GTTACTGGCCGCGCTGCAGGCAGGTAAGGGCGAGGCGTCACTGAAGGCTGCTGGCCTGCGCTTTGGTGCCGAGCAGACAC
TGACCCGTGCCTCTGAGGATCGTCAGCTGACGGATACGGTATTCGCGATGCCGCACCCACAGACTGATAAGCCGGTGTAC
GGCATATCGACAGATCGTCATGACAATATCGCGTTGATTCGCCTGAACGCCGTAACGGCGGGTCATCTGTCGGCGGAGCA
AATGAAGGCATTCGCCTCTCAGATGCTCACCGGTGAGACCGGGATCACCTTCGATGCCCTGATGGATAACCTGCGCGATA
ATGCCAAGATCAAGCTGGGCGCGGCGGCAGATGTGCAGTAA

Upstream 100 bases:

>100_bases
CAGTTAATCTAATCGTGTGCTGTGCGTATACGGGCCATGGCCTGGAACAAAGCGGAGTCACAACGTATTACCAACAATCA
CAGCGGAGTGTTGCCACACT

Downstream 100 bases:

>100_bases
TTCCCATCGCCGTGGCTGAGTTGATGTAACACCAAAAGGCCGCATTCGCGGCCTTTTGCATATTGCGCTATCCGGCTTTG
CCGGACCCATCTCAGAAGGG

Product: peptidyl-prolyl cis-trans isomerase (rotamase D)

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 626; Mature: 626

Protein sequence:

>626_residues
MMDNLRAAANHVVLKVILALIIISFVLTGVGNYLIGGSGDYAAKVDGQEIGRAQLEQAVQNERSRLQQQLGDQFSVLAGN
EGYMKELRKQVLSRMIDDVLLDQYAKKLNLAISDAQVKEAIRAMPYFQSDNHFDNAKYLDMVARLGLSPDTYAQLVRQQL
VTQQLIQGFTATGFTLPAEVNALAALTMQQRQVSLATIDISKLMPLQQVSDAELQGYYQQHQSSFIAPETVKVRYIEMDA
AAINDKMTVSNAEISAYYDQHKGSFTQPARSDYSVIQVKTEAEAKAIAGQLASGADFATLAKEKSTDIISRKNGGELGWL
EQETTPDEIRAAKLSHKGDVSAPIASSVGYLIVRLNGIQPAVVKPLSEVRAEIADKVKQQKALDAFYALQQKVSDAATND
NDSLAGAEDAAGVKATETGWFSRDSVPQVLDFKPITQAIFDGSLFGENGTPGSNSDVISVEGDRAFVLRVSEHKPEAVKP
FDQVRDQVTELLKRQKAIAQARSDGEKLLAALQAGKGEASLKAAGLRFGAEQTLTRASEDRQLTDTVFAMPHPQTDKPVY
GISTDRHDNIALIRLNAVTAGHLSAEQMKAFASQMLTGETGITFDALMDNLRDNAKIKLGAAADVQ

Sequences:

>Translated_626_residues
MMDNLRAAANHVVLKVILALIIISFVLTGVGNYLIGGSGDYAAKVDGQEIGRAQLEQAVQNERSRLQQQLGDQFSVLAGN
EGYMKELRKQVLSRMIDDVLLDQYAKKLNLAISDAQVKEAIRAMPYFQSDNHFDNAKYLDMVARLGLSPDTYAQLVRQQL
VTQQLIQGFTATGFTLPAEVNALAALTMQQRQVSLATIDISKLMPLQQVSDAELQGYYQQHQSSFIAPETVKVRYIEMDA
AAINDKMTVSNAEISAYYDQHKGSFTQPARSDYSVIQVKTEAEAKAIAGQLASGADFATLAKEKSTDIISRKNGGELGWL
EQETTPDEIRAAKLSHKGDVSAPIASSVGYLIVRLNGIQPAVVKPLSEVRAEIADKVKQQKALDAFYALQQKVSDAATND
NDSLAGAEDAAGVKATETGWFSRDSVPQVLDFKPITQAIFDGSLFGENGTPGSNSDVISVEGDRAFVLRVSEHKPEAVKP
FDQVRDQVTELLKRQKAIAQARSDGEKLLAALQAGKGEASLKAAGLRFGAEQTLTRASEDRQLTDTVFAMPHPQTDKPVY
GISTDRHDNIALIRLNAVTAGHLSAEQMKAFASQMLTGETGITFDALMDNLRDNAKIKLGAAADVQ
>Mature_626_residues
MMDNLRAAANHVVLKVILALIIISFVLTGVGNYLIGGSGDYAAKVDGQEIGRAQLEQAVQNERSRLQQQLGDQFSVLAGN
EGYMKELRKQVLSRMIDDVLLDQYAKKLNLAISDAQVKEAIRAMPYFQSDNHFDNAKYLDMVARLGLSPDTYAQLVRQQL
VTQQLIQGFTATGFTLPAEVNALAALTMQQRQVSLATIDISKLMPLQQVSDAELQGYYQQHQSSFIAPETVKVRYIEMDA
AAINDKMTVSNAEISAYYDQHKGSFTQPARSDYSVIQVKTEAEAKAIAGQLASGADFATLAKEKSTDIISRKNGGELGWL
EQETTPDEIRAAKLSHKGDVSAPIASSVGYLIVRLNGIQPAVVKPLSEVRAEIADKVKQQKALDAFYALQQKVSDAATND
NDSLAGAEDAAGVKATETGWFSRDSVPQVLDFKPITQAIFDGSLFGENGTPGSNSDVISVEGDRAFVLRVSEHKPEAVKP
FDQVRDQVTELLKRQKAIAQARSDGEKLLAALQAGKGEASLKAAGLRFGAEQTLTRASEDRQLTDTVFAMPHPQTDKPVY
GISTDRHDNIALIRLNAVTAGHLSAEQMKAFASQMLTGETGITFDALMDNLRDNAKIKLGAAADVQ

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=626, Percent_Identity=56.5495207667732, Blast_Score=715, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 67982; Mature: 67982

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDNLRAAANHVVLKVILALIIISFVLTGVGNYLIGGSGDYAAKVDGQEIGRAQLEQAVQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCEEECCHHHHHHHHHHHHHH
NERSRLQQQLGDQFSVLAGNEGYMKELRKQVLSRMIDDVLLDQYAKKLNLAISDAQVKEA
HHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHH
IRAMPYFQSDNHFDNAKYLDMVARLGLSPDTYAQLVRQQLVTQQLIQGFTATGFTLPAEV
HHHCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
NALAALTMQQRQVSLATIDISKLMPLQQVSDAELQGYYQQHQSSFIAPETVKVRYIEMDA
HHHHHHHHHHHHHHHEEEEHHHCCCHHHCCCHHHHHHHHHHHCCCCCCCEEEEEEEEECH
AAINDKMTVSNAEISAYYDQHKGSFTQPARSDYSVIQVKTEAEAKAIAGQLASGADFATL
HHCCCCEEECCCHHHHHHHHCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHCCCCCHHHH
AKEKSTDIISRKNGGELGWLEQETTPDEIRAAKLSHKGDVSAPIASSVGYLIVRLNGIQP
HHHHCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHCCCEEEEEECCCCH
AVVKPLSEVRAEIADKVKQQKALDAFYALQQKVSDAATNDNDSLAGAEDAAGVKATETGW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
FSRDSVPQVLDFKPITQAIFDGSLFGENGTPGSNSDVISVEGDRAFVLRVSEHKPEAVKP
CCCCCCCHHHCCCHHHHHHHCCCEECCCCCCCCCCCEEEECCCEEEEEEECCCCCCCCCC
FDQVRDQVTELLKRQKAIAQARSDGEKLLAALQAGKGEASLKAAGLRFGAEQTLTRASED
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHCC
RQLTDTVFAMPHPQTDKPVYGISTDRHDNIALIRLNAVTAGHLSAEQMKAFASQMLTGET
CHHHHHEEECCCCCCCCCEECCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHCCCC
GITFDALMDNLRDNAKIKLGAAADVQ
CCCHHHHHHHHCCCCEEEECCCCCCC
>Mature Secondary Structure
MMDNLRAAANHVVLKVILALIIISFVLTGVGNYLIGGSGDYAAKVDGQEIGRAQLEQAVQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCEEECCHHHHHHHHHHHHHH
NERSRLQQQLGDQFSVLAGNEGYMKELRKQVLSRMIDDVLLDQYAKKLNLAISDAQVKEA
HHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHH
IRAMPYFQSDNHFDNAKYLDMVARLGLSPDTYAQLVRQQLVTQQLIQGFTATGFTLPAEV
HHHCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
NALAALTMQQRQVSLATIDISKLMPLQQVSDAELQGYYQQHQSSFIAPETVKVRYIEMDA
HHHHHHHHHHHHHHHEEEEHHHCCCHHHCCCHHHHHHHHHHHCCCCCCCEEEEEEEEECH
AAINDKMTVSNAEISAYYDQHKGSFTQPARSDYSVIQVKTEAEAKAIAGQLASGADFATL
HHCCCCEEECCCHHHHHHHHCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHCCCCCHHHH
AKEKSTDIISRKNGGELGWLEQETTPDEIRAAKLSHKGDVSAPIASSVGYLIVRLNGIQP
HHHHCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHCCCEEEEEECCCCH
AVVKPLSEVRAEIADKVKQQKALDAFYALQQKVSDAATNDNDSLAGAEDAAGVKATETGW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
FSRDSVPQVLDFKPITQAIFDGSLFGENGTPGSNSDVISVEGDRAFVLRVSEHKPEAVKP
CCCCCCCHHHCCCHHHHHHHCCCEECCCCCCCCCCCEEEECCCEEEEEEECCCCCCCCCC
FDQVRDQVTELLKRQKAIAQARSDGEKLLAALQAGKGEASLKAAGLRFGAEQTLTRASED
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHCC
RQLTDTVFAMPHPQTDKPVYGISTDRHDNIALIRLNAVTAGHLSAEQMKAFASQMLTGET
CHHHHHEEECCCCCCCCCEECCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHCCCC
GITFDALMDNLRDNAKIKLGAAADVQ
CCCHHHHHHHHCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]