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The map label for this gene is hit [H]

Identifier: 238917888

GI number: 238917888

Start: 2039878

End: 2040294

Strand: Reverse

Name: hit [H]

Synonym: EUBELI_01975

Alternate gene names: 238917888

Gene position: 2040294-2039878 (Counterclockwise)

Preceding gene: 238917890

Following gene: 238917887

Centisome position: 95.15

GC content: 35.49

Gene sequence:

>417_bases
ATGAAAAAGGATGATTGTATTTTTTGCAAGCTGGCAAACGGCGAGATTCCAACAAATGCTCTTTATGAGGATGATATTGT
AAAAGTTATTTTCGATGCAAGTCCTGCCGCTAAAGGACATGTACTTATATTGCCGAAGGAACATTTTGACAATATATATG
AACTTGATGATGACACTGCCGCACATGTATTTAAAGTAGCAGCTAAGATTTCTAAAGCGTATAAGAAAGCATTGGATTTT
GATGGACTTAATATTGTTCAGAACAATGGAGAAGTAGCAGGGCAGACAGTATTTCATTTCCATATGCATATTATTCCTAG
AATTAAAGGTGATACAGTTAATGTTGGATGGGTTCCGGGAACTGCAGATAATGACACCATAGCATCAATAGTAGAAAAAG
TTACACCTTATCTTTAA

Upstream 100 bases:

>100_bases
TTAAGTTATCATATAAAAGTATATAATAAAGTATATACATATTCGAAGTACATGTAAACAAAAGTATTTCGACAAATTTC
GCGCAAAGTGAGGAAATAGT

Downstream 100 bases:

>100_bases
TGTTTGTATATGTTATATAATGAGGATATGAATAACGGATATTAAGCGGGAAACCGTAATGATATATAGAAAGAGGAGAA
AGCATGATTAAATTAAGTGA

Product: cell-cycle regulation Hit-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 138; Mature: 138

Protein sequence:

>138_residues
MKKDDCIFCKLANGEIPTNALYEDDIVKVIFDASPAAKGHVLILPKEHFDNIYELDDDTAAHVFKVAAKISKAYKKALDF
DGLNIVQNNGEVAGQTVFHFHMHIIPRIKGDTVNVGWVPGTADNDTIASIVEKVTPYL

Sequences:

>Translated_138_residues
MKKDDCIFCKLANGEIPTNALYEDDIVKVIFDASPAAKGHVLILPKEHFDNIYELDDDTAAHVFKVAAKISKAYKKALDF
DGLNIVQNNGEVAGQTVFHFHMHIIPRIKGDTVNVGWVPGTADNDTIASIVEKVTPYL
>Mature_138_residues
MKKDDCIFCKLANGEIPTNALYEDDIVKVIFDASPAAKGHVLILPKEHFDNIYELDDDTAAHVFKVAAKISKAYKKALDF
DGLNIVQNNGEVAGQTVFHFHMHIIPRIKGDTVNVGWVPGTADNDTIASIVEKVTPYL

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI4885413, Length=119, Percent_Identity=33.6134453781513, Blast_Score=63, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17506713, Length=120, Percent_Identity=32.5, Blast_Score=72, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6320078, Length=126, Percent_Identity=35.7142857142857, Blast_Score=87, Evalue=7e-19,
Organism=Drosophila melanogaster, GI28574010, Length=120, Percent_Identity=30.8333333333333, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24581222, Length=120, Percent_Identity=30.8333333333333, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: NA

Molecular weight: Translated: 15225; Mature: 15225

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS00892 HIT_1 ; PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKDDCIFCKLANGEIPTNALYEDDIVKVIFDASPAAKGHVLILPKEHFDNIYELDDDTA
CCCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEHHHCCCEEECCCCHH
AHVFKVAAKISKAYKKALDFDGLNIVQNNGEVAGQTVFHFHMHIIPRIKGDTVNVGWVPG
HHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEEEEEEEEEEEECCCEEEEEECCC
TADNDTIASIVEKVTPYL
CCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MKKDDCIFCKLANGEIPTNALYEDDIVKVIFDASPAAKGHVLILPKEHFDNIYELDDDTA
CCCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEHHHCCCEEECCCCHH
AHVFKVAAKISKAYKKALDFDGLNIVQNNGEVAGQTVFHFHMHIIPRIKGDTVNVGWVPG
HHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEEEEEEEEEEEECCCEEEEEECCC
TADNDTIASIVEKVTPYL
CCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]