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The map label for this gene is ttcA [H]

Identifier: 238917758

GI number: 238917758

Start: 1897742

End: 1898980

Strand: Reverse

Name: ttcA [H]

Synonym: EUBELI_01839

Alternate gene names: 238917758

Gene position: 1898980-1897742 (Counterclockwise)

Preceding gene: 238917759

Following gene: 238917757

Centisome position: 88.56

GC content: 39.23

Gene sequence:

>1239_bases
ATGATGAAAACAATAATTGATTACCAGAATGATGAAAGAGAAAAGGTTCTGCTTGATGTAAGAGACAAGCAGGAATTCGA
GAAGGAAACATATCCCGGAGCAAGAAATTGGTACTGGGAGGAACTGATTAAGGTGCTTGAAGAAACACCGGAGGAATTCA
CACAGCAGTTTGATAAGAGTGTTCCTATATATCTTCTGTGCTATACGGGTCTGCACAGTGATGATCTGGCAGATATTCTT
GAAGAAATGGGTTATGAGGTCTACAGTCTGTATGGCGGCTGGGGCGCTTATATGAAGTGGAAGTTCGAGAATTATGTCAA
GAAAGCACAGGCAGAGAATGAGCTTTCAGGTGAAGAAAGAGTTAAGGAAATAGAGCGGAGCATAGTCAAGAAGTTCAGAA
AGCCTATATGGAGAAAGTTCACACAGGCACTTAATGAATACGACCTTATACAGGATGGAGATAAGATTGCAGTCTGTATA
TCAGGCGGTAAGGACTCAATGCTTATGGCGAAGCTTTTTCAGGAGCTTAAGAGGCATGGAAAGAATAATTTTGAACTTGT
ATTTCTGGTTATGAATCCGGGATACAATAATATTAATTATCAGGTTATTCTTAATAATGCAAAGATTCTTGATATTCCTA
TAACCGTGTTCAAATCAGAGATATTTGATACGGTTGCAGATATAGAGGAGTCTCCATGTTATCTGTGTGCCCGAATGAGA
AGAGGATATCTGTATAGTAAGGCTAAAGAGCTTGGATGTAACAAGATAGCGTTAGGTCATCATTATGATGATGTTATTGA
GACAATTCTTATGGGAATGTTGTATGGTGCGCAGATTCAGACTATGATGCCAAAGCTTCACAGCACTAATTTTGAGGGCA
TGGAGCTTATAAGACCGCTTTACCTTATAAGAGAAGCAGATATAATACATTGGAGAGATTATAATAATCTTGCATTTATA
CAGTGTGCATGCAGGCTTACAGAGAGCTGTGCTTCATGTGGCGGAACAGAAAAGGGTTCTAAGAGAGGCGAGATTAAGCA
GCTTATCAAAGACCTGACTAAGGTAAGCCCTTACATTGAGAAGAACATTTTCAGAAGTGTTGAAAACGTTAATCTTGATA
CAGTTATTGCATATAAGCAGTATGGTGTTAAGCATAATTTCCTTGAAAGATATGAGGAAATGGGAAGACTCAACGGTGCG
TCAGGCAGCCAGACAGCAGATAATAAGGAGATGGAATAA

Upstream 100 bases:

>100_bases
GCCGGCGTAGACAGCAAGGCAGGAACTATTGTGTTCTCACTTCCTGTTACAAGTACGGCAGGACTGCGTATTCTTGAGGA
TTCGCAGGATGAAGAGGTTG

Downstream 100 bases:

>100_bases
ATATGTCATCACAATATAATTGCGATTACTGCAACAACCTTGTATATGACGAGGAGATTGAAGGATATGTATGTGATGTT
GATATGGACGAGGACGATTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MMKTIIDYQNDEREKVLLDVRDKQEFEKETYPGARNWYWEELIKVLEETPEEFTQQFDKSVPIYLLCYTGLHSDDLADIL
EEMGYEVYSLYGGWGAYMKWKFENYVKKAQAENELSGEERVKEIERSIVKKFRKPIWRKFTQALNEYDLIQDGDKIAVCI
SGGKDSMLMAKLFQELKRHGKNNFELVFLVMNPGYNNINYQVILNNAKILDIPITVFKSEIFDTVADIEESPCYLCARMR
RGYLYSKAKELGCNKIALGHHYDDVIETILMGMLYGAQIQTMMPKLHSTNFEGMELIRPLYLIREADIIHWRDYNNLAFI
QCACRLTESCASCGGTEKGSKRGEIKQLIKDLTKVSPYIEKNIFRSVENVNLDTVIAYKQYGVKHNFLERYEEMGRLNGA
SGSQTADNKEME

Sequences:

>Translated_412_residues
MMKTIIDYQNDEREKVLLDVRDKQEFEKETYPGARNWYWEELIKVLEETPEEFTQQFDKSVPIYLLCYTGLHSDDLADIL
EEMGYEVYSLYGGWGAYMKWKFENYVKKAQAENELSGEERVKEIERSIVKKFRKPIWRKFTQALNEYDLIQDGDKIAVCI
SGGKDSMLMAKLFQELKRHGKNNFELVFLVMNPGYNNINYQVILNNAKILDIPITVFKSEIFDTVADIEESPCYLCARMR
RGYLYSKAKELGCNKIALGHHYDDVIETILMGMLYGAQIQTMMPKLHSTNFEGMELIRPLYLIREADIIHWRDYNNLAFI
QCACRLTESCASCGGTEKGSKRGEIKQLIKDLTKVSPYIEKNIFRSVENVNLDTVIAYKQYGVKHNFLERYEEMGRLNGA
SGSQTADNKEME
>Mature_412_residues
MMKTIIDYQNDEREKVLLDVRDKQEFEKETYPGARNWYWEELIKVLEETPEEFTQQFDKSVPIYLLCYTGLHSDDLADIL
EEMGYEVYSLYGGWGAYMKWKFENYVKKAQAENELSGEERVKEIERSIVKKFRKPIWRKFTQALNEYDLIQDGDKIAVCI
SGGKDSMLMAKLFQELKRHGKNNFELVFLVMNPGYNNINYQVILNNAKILDIPITVFKSEIFDTVADIEESPCYLCARMR
RGYLYSKAKELGCNKIALGHHYDDVIETILMGMLYGAQIQTMMPKLHSTNFEGMELIRPLYLIREADIIHWRDYNNLAFI
QCACRLTESCASCGGTEKGSKRGEIKQLIKDLTKVSPYIEKNIFRSVENVNLDTVIAYKQYGVKHNFLERYEEMGRLNGA
SGSQTADNKEME

Specific function: Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) [H]

COG id: COG0037

COG function: function code D; Predicted ATPase of the PP-loop superfamily implicated in cell cycle control

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TtcA family [H]

Homologues:

Organism=Escherichia coli, GI1787606, Length=255, Percent_Identity=30.9803921568627, Blast_Score=135, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI193211090, Length=231, Percent_Identity=26.4069264069264, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17540090, Length=242, Percent_Identity=26.0330578512397, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24651972, Length=254, Percent_Identity=26.3779527559055, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012089
- InterPro:   IPR014729
- InterPro:   IPR011063 [H]

Pfam domain/function: PF01171 ATP_bind_3 [H]

EC number: NA

Molecular weight: Translated: 47994; Mature: 47994

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKTIIDYQNDEREKVLLDVRDKQEFEKETYPGARNWYWEELIKVLEETPEEFTQQFDKS
CCCCCCCCCCCCCCEEEEECHHHHHHHHHCCCCCCCHHHHHHHHHHHHCHHHHHHHHCCC
VPIYLLCYTGLHSDDLADILEEMGYEVYSLYGGWGAYMKWKFENYVKKAQAENELSGEER
CCEEEEEECCCCCHHHHHHHHHCCHHHHHHHCCCCHHEEEHHHHHHHHHHHHHCCCHHHH
VKEIERSIVKKFRKPIWRKFTQALNEYDLIQDGDKIAVCISGGKDSMLMAKLFQELKRHG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHC
KNNFELVFLVMNPGYNNINYQVILNNAKILDIPITVFKSEIFDTVADIEESPCYLCARMR
CCCEEEEEEEECCCCCCCEEEEEECCCEEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RGYLYSKAKELGCNKIALGHHYDDVIETILMGMLYGAQIQTMMPKLHSTNFEGMELIRPL
HCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
YLIREADIIHWRDYNNLAFIQCACRLTESCASCGGTEKGSKRGEIKQLIKDLTKVSPYIE
HHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCHHHH
KNIFRSVENVNLDTVIAYKQYGVKHNFLERYEEMGRLNGASGSQTADNKEME
HHHHHHHHCCCCCEEEHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MMKTIIDYQNDEREKVLLDVRDKQEFEKETYPGARNWYWEELIKVLEETPEEFTQQFDKS
CCCCCCCCCCCCCCEEEEECHHHHHHHHHCCCCCCCHHHHHHHHHHHHCHHHHHHHHCCC
VPIYLLCYTGLHSDDLADILEEMGYEVYSLYGGWGAYMKWKFENYVKKAQAENELSGEER
CCEEEEEECCCCCHHHHHHHHHCCHHHHHHHCCCCHHEEEHHHHHHHHHHHHHCCCHHHH
VKEIERSIVKKFRKPIWRKFTQALNEYDLIQDGDKIAVCISGGKDSMLMAKLFQELKRHG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHC
KNNFELVFLVMNPGYNNINYQVILNNAKILDIPITVFKSEIFDTVADIEESPCYLCARMR
CCCEEEEEEEECCCCCCCEEEEEECCCEEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RGYLYSKAKELGCNKIALGHHYDDVIETILMGMLYGAQIQTMMPKLHSTNFEGMELIRPL
HCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
YLIREADIIHWRDYNNLAFIQCACRLTESCASCGGTEKGSKRGEIKQLIKDLTKVSPYIE
HHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCHHHH
KNIFRSVENVNLDTVIAYKQYGVKHNFLERYEEMGRLNGASGSQTADNKEME
HHHHHHHHCCCCCEEEHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA