BacMap

Definition	Eubacterium eligens ATCC 27750 chromosome, complete genome.
Accession	NC_012778
Length	2,144,190

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The map label for this gene is bcrA [H]

Identifier: 238917670

GI number: 238917670

Start: 1814265

End: 1815113

Strand: Reverse

Name: bcrA [H]

Synonym: EUBELI_01750

Alternate gene names: 238917670

Gene position: 1815113-1814265 (Counterclockwise)

Preceding gene: 238917671

Following gene: 238917669

Centisome position: 84.65

GC content: 40.28

Gene sequence:

>849_bases
ATGATAACAATGCAGAATGTCCGAAAAAAATATAAGGACTTTGAACTGGAACTATCCTTGGAAATACCAGAGGGGAGAAT
TACAGGGTTTGTAGGAAAAAACGGCGCAGGAAAAAGTACGGCAATTAAACTGATACTTGGACTGGTAAAGCCGGATGCTG
GAAAGATTTGTGTGTTTGGTAATGAAGGTGGAGAGCTTCCGGCTGCGGTAAAGCAGAAAATCGGAGTATCTTTGACGGAG
GCAGGCTTTAGTTCACAATTTACGGTGGAAGATGTCTGGCATATCCTTGCTAAAATGTATCCTGATTTCCAGAAGGATTT
TTTTGACCAAAAATGTGAGGCTTTAAAGCTTCCACGGAAGAAGAAATTAAAAGAATTTTCCACAGGTATGAAAGCAAAAC
TGAGGGTGCTGACAGCAATCAGCCATAAAGCTGATTTGTTGATTTTAGATGAGCCGACCGCAGGGCTTGATGTGGAGGCA
AGGAATGAAATCCTTGATTTGCTACGGGAATATATAGCGCAGGACGAGAAGCGCACAATATTGATTACATCGCACATTTC
CACAGATTTGGAGTCACTTTGTGACGACATTTATCTCATTCATGACGGAAAAATCATTTTGCATGAGGACACAGATGTTA
TTTTAGAACAGTATGGTATTTTGAAGGTGAATGAGGAACAATACAGGACATTAGACAAGACAGCAGTCATAAAAGTACAG
AAAGAAACTTATGGTTATGCCTGCTTTACTAATGACAGAAGATTTTATCAGGAAAATTATCCGCAGATTGCGGTGGAGCA
GGGCGGAATTGATGAATTAATTCTTATGATGACGGGAGGGTACAGATAA

Upstream 100 bases:

>100_bases
TTGACAAAGCCATTGACCGGGCAGTGGCAATTGGGATGGAGAAAGAAGAAATCTTAGAGGTTGTAAAGCTCATACTTGAT
GAGAAATAGAAAGGCGAATT

Downstream 100 bases:

>100_bases
TGGCAGGATTAGTAGAAAAAGATTTCCGGTTAATTTGGTGTAATAAACAGGCATTAATTTTCCTTCTTATCATTGGAGTG
GTGATAGGATTACAGAATGA

Product: ABC-2 type transport system ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MITMQNVRKKYKDFELELSLEIPEGRITGFVGKNGAGKSTAIKLILGLVKPDAGKICVFGNEGGELPAAVKQKIGVSLTE
AGFSSQFTVEDVWHILAKMYPDFQKDFFDQKCEALKLPRKKKLKEFSTGMKAKLRVLTAISHKADLLILDEPTAGLDVEA
RNEILDLLREYIAQDEKRTILITSHISTDLESLCDDIYLIHDGKIILHEDTDVILEQYGILKVNEEQYRTLDKTAVIKVQ
KETYGYACFTNDRRFYQENYPQIAVEQGGIDELILMMTGGYR

Sequences:

>Translated_282_residues
MITMQNVRKKYKDFELELSLEIPEGRITGFVGKNGAGKSTAIKLILGLVKPDAGKICVFGNEGGELPAAVKQKIGVSLTE
AGFSSQFTVEDVWHILAKMYPDFQKDFFDQKCEALKLPRKKKLKEFSTGMKAKLRVLTAISHKADLLILDEPTAGLDVEA
RNEILDLLREYIAQDEKRTILITSHISTDLESLCDDIYLIHDGKIILHEDTDVILEQYGILKVNEEQYRTLDKTAVIKVQ
KETYGYACFTNDRRFYQENYPQIAVEQGGIDELILMMTGGYR
>Mature_282_residues
MITMQNVRKKYKDFELELSLEIPEGRITGFVGKNGAGKSTAIKLILGLVKPDAGKICVFGNEGGELPAAVKQKIGVSLTE
AGFSSQFTVEDVWHILAKMYPDFQKDFFDQKCEALKLPRKKKLKEFSTGMKAKLRVLTAISHKADLLILDEPTAGLDVEA
RNEILDLLREYIAQDEKRTILITSHISTDLESLCDDIYLIHDGKIILHEDTDVILEQYGILKVNEEQYRTLDKTAVIKVQ
KETYGYACFTNDRRFYQENYPQIAVEQGGIDELILMMTGGYR

Specific function: Part of the binding-protein-dependent transport system for bacitracin that confer resistance to this antibiotic. Probably responsible for energy coupling to the transport system [H]

COG id: COG1131

COG function: function code V; ABC-type multidrug transport system, ATPase component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI21536376, Length=214, Percent_Identity=32.2429906542056, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI47078218, Length=214, Percent_Identity=31.3084112149533, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI45446740, Length=214, Percent_Identity=30.8411214953271, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI116734710, Length=213, Percent_Identity=28.169014084507, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI150417984, Length=194, Percent_Identity=31.4432989690722, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI105990541, Length=194, Percent_Identity=31.4432989690722, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI27477115, Length=203, Percent_Identity=30.0492610837438, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI153792144, Length=200, Percent_Identity=30, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI31657092, Length=228, Percent_Identity=28.5087719298246, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI6005701, Length=203, Percent_Identity=29.064039408867, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI27881501, Length=196, Percent_Identity=30.1020408163265, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI30795238, Length=196, Percent_Identity=30.1020408163265, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI27262624, Length=225, Percent_Identity=28.4444444444444, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI27262626, Length=225, Percent_Identity=28.4444444444444, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI27436953, Length=236, Percent_Identity=27.1186440677966, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1786319, Length=241, Percent_Identity=29.4605809128631, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI48994943, Length=213, Percent_Identity=28.169014084507, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI87081782, Length=246, Percent_Identity=28.0487804878049, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1789593, Length=234, Percent_Identity=26.9230769230769, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1790190, Length=231, Percent_Identity=26.8398268398268, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1789751, Length=237, Percent_Identity=30.379746835443, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1786253, Length=228, Percent_Identity=24.5614035087719, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787758, Length=202, Percent_Identity=25.7425742574257, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI48995001, Length=192, Percent_Identity=27.0833333333333, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787712, Length=210, Percent_Identity=24.2857142857143, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787792, Length=202, Percent_Identity=29.2079207920792, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788761, Length=215, Percent_Identity=24.1860465116279, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788165, Length=191, Percent_Identity=27.7486910994764, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1789586, Length=206, Percent_Identity=27.6699029126214, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1787370, Length=212, Percent_Identity=24.5283018867925, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789672, Length=219, Percent_Identity=26.027397260274, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788472, Length=222, Percent_Identity=25.2252252252252, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87081709, Length=212, Percent_Identity=24.0566037735849, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI48994883, Length=209, Percent_Identity=24.8803827751196, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788210, Length=201, Percent_Identity=23.8805970149254, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788450, Length=201, Percent_Identity=25.3731343283582, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1787143, Length=215, Percent_Identity=23.7209302325581, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71983516, Length=207, Percent_Identity=29.951690821256, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71983523, Length=207, Percent_Identity=29.951690821256, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71983510, Length=207, Percent_Identity=29.951690821256, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17510237, Length=206, Percent_Identity=31.0679611650485, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI115533608, Length=188, Percent_Identity=31.9148936170213, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193202878, Length=191, Percent_Identity=29.8429319371728, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17565586, Length=220, Percent_Identity=26.8181818181818, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193208177, Length=245, Percent_Identity=24.4897959183673, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28574150, Length=194, Percent_Identity=31.9587628865979, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI116007328, Length=194, Percent_Identity=31.9587628865979, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24650853, Length=241, Percent_Identity=27.8008298755187, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24650855, Length=241, Percent_Identity=27.8008298755187, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI281362751, Length=214, Percent_Identity=28.0373831775701, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24582014, Length=209, Percent_Identity=29.6650717703349, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24582012, Length=209, Percent_Identity=29.6650717703349, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI221512771, Length=212, Percent_Identity=29.2452830188679, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI85725262, Length=206, Percent_Identity=30.5825242718447, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24643674, Length=227, Percent_Identity=25.9911894273128, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28573571, Length=214, Percent_Identity=27.1028037383178, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI28573573, Length=214, Percent_Identity=27.1028037383178, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24666092, Length=215, Percent_Identity=27.906976744186, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24581191, Length=211, Percent_Identity=28.436018957346, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24581189, Length=211, Percent_Identity=28.436018957346, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24581193, Length=211, Percent_Identity=28.436018957346, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24581195, Length=211, Percent_Identity=28.436018957346, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24648314, Length=204, Percent_Identity=23.0392156862745, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28574744, Length=236, Percent_Identity=25.8474576271186, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 31919; Mature: 31919

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITMQNVRKKYKDFELELSLEIPEGRITGFVGKNGAGKSTAIKLILGLVKPDAGKICVFG
CCCHHHHHHHHCCEEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEEC
NEGGELPAAVKQKIGVSLTEAGFSSQFTVEDVWHILAKMYPDFQKDFFDQKCEALKLPRK
CCCCCCCHHHHHHHCCEEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHH
KKLKEFSTGMKAKLRVLTAISHKADLLILDEPTAGLDVEARNEILDLLREYIAQDEKRTI
HHHHHHHCCHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCEE
LITSHISTDLESLCDDIYLIHDGKIILHEDTDVILEQYGILKVNEEQYRTLDKTAVIKVQ
EEEECCHHHHHHHHCCEEEEECCEEEEECCHHHHHHHCCCEEECHHHHHHHCCEEEEEEE
KETYGYACFTNDRRFYQENYPQIAVEQGGIDELILMMTGGYR
CCCCCEEEEECCCHHHHCCCCEEEEECCCHHEEEEEECCCCC
>Mature Secondary Structure
MITMQNVRKKYKDFELELSLEIPEGRITGFVGKNGAGKSTAIKLILGLVKPDAGKICVFG
CCCHHHHHHHHCCEEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEEC
NEGGELPAAVKQKIGVSLTEAGFSSQFTVEDVWHILAKMYPDFQKDFFDQKCEALKLPRK
CCCCCCCHHHHHHHCCEEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHH
KKLKEFSTGMKAKLRVLTAISHKADLLILDEPTAGLDVEARNEILDLLREYIAQDEKRTI
HHHHHHHCCHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCEE
LITSHISTDLESLCDDIYLIHDGKIILHEDTDVILEQYGILKVNEEQYRTLDKTAVIKVQ
EEEECCHHHHHHHHCCEEEEECCEEEEECCHHHHHHHCCCEEECHHHHHHHCCEEEEEEE
KETYGYACFTNDRRFYQENYPQIAVEQGGIDELILMMTGGYR
CCCCCEEEEECCCHHHHCCCCEEEEECCCHHEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7476193 [H]