Click here to switch to the map view.

The map label for this gene is accB [H]

Identifier: 238917648

GI number: 238917648

Start: 1794704

End: 1795156

Strand: Reverse

Name: accB [H]

Synonym: EUBELI_01727

Alternate gene names: 238917648

Gene position: 1795156-1794704 (Counterclockwise)

Preceding gene: 238917649

Following gene: 238917647

Centisome position: 83.72

GC content: 41.06

Gene sequence:

>453_bases
ATGGATATTAATGATATTTATGGGATTATAGATAAGTTTGATGCAAGTGGATGCAGCGAACTGAATTTGGAGATGAATGG
CATATGCCTTGGACTGAAGAAAACAATGCACGAAGCCATATGTGATGTGCCTGTAAAGAGAGATATTGTTCGCATTAATA
CAGAACAGGAACAGACCGTTACAACTATTCAGGACGTACAGCCACAGTCAGATGAGCATATTAAAGAAATTAAAGCGCCA
CTGGTTGGAACTTTCTATACAGCAGCAGGTCCTGATGAGGAACCTTTTGTAAAACCAGGGCAGAGCGTTCATGCAGGTGA
TGTTATTGGAATAATTGAAGCAATGAAGCTGATGAACGAAGTTACAGCAGATTGTGACGGTACGGTTAAGGAAGTGGCAG
CAGAGAATGGCACTATGGTTGAGTATGGACAGCCGCTTGTAATCCTTAATTAA

Upstream 100 bases:

>100_bases
CAGAAGAAGAACTTCCTAATCTTACATCAGTTAAAGCAATTGTTGAGTATGTTGACAAGAATGCAGCTTAACATAAAGAT
TTTAAGGAAGACAGTTTGTT

Downstream 100 bases:

>100_bases
CGGAGGTAGCAGAAGTGTTTAAGAGAATACTGATAGCAAACCGTGGTGAAATAGCGTTAAGGATAATCAGATGCTGCCGT
GAGATGGATGTAGAAACCGT

Product: oxaloacetate decarboxylase

Products: Malonyl-CoA; malonyl-CoA; phosphate; ADP [C]

Alternate protein names: BCCP [H]

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MDINDIYGIIDKFDASGCSELNLEMNGICLGLKKTMHEAICDVPVKRDIVRINTEQEQTVTTIQDVQPQSDEHIKEIKAP
LVGTFYTAAGPDEEPFVKPGQSVHAGDVIGIIEAMKLMNEVTADCDGTVKEVAAENGTMVEYGQPLVILN

Sequences:

>Translated_150_residues
MDINDIYGIIDKFDASGCSELNLEMNGICLGLKKTMHEAICDVPVKRDIVRINTEQEQTVTTIQDVQPQSDEHIKEIKAP
LVGTFYTAAGPDEEPFVKPGQSVHAGDVIGIIEAMKLMNEVTADCDGTVKEVAAENGTMVEYGQPLVILN
>Mature_150_residues
MDINDIYGIIDKFDASGCSELNLEMNGICLGLKKTMHEAICDVPVKRDIVRINTEQEQTVTTIQDVQPQSDEHIKEIKAP
LVGTFYTAAGPDEEPFVKPGQSVHAGDVIGIIEAMKLMNEVTADCDGTVKEVAAENGTMVEYGQPLVILN

Specific function: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA [H]

COG id: COG0511

COG function: function code I; Biotin carboxyl carrier protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotinyl-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789653, Length=159, Percent_Identity=33.9622641509434, Blast_Score=89, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001249
- InterPro:   IPR001882
- InterPro:   IPR000089
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00364 Biotin_lipoyl [H]

EC number: NA

Molecular weight: Translated: 16336; Mature: 16336

Theoretical pI: Translated: 4.09; Mature: 4.09

Prosite motif: PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDINDIYGIIDKFDASGCSELNLEMNGICLGLKKTMHEAICDVPVKRDIVRINTEQEQTV
CCCHHHHHHHHHCCCCCCCCCCEEECCEEEHHHHHHHHHHHCCCCCCCEEEECCCCHHHH
TTIQDVQPQSDEHIKEIKAPLVGTFYTAAGPDEEPFVKPGQSVHAGDVIGIIEAMKLMNE
HHHHHCCCCCHHHHHHHHHCHHHEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
VTADCDGTVKEVAAENGTMVEYGQPLVILN
HCCCCCCHHHHHHHCCCCEEECCCCEEEEC
>Mature Secondary Structure
MDINDIYGIIDKFDASGCSELNLEMNGICLGLKKTMHEAICDVPVKRDIVRINTEQEQTV
CCCHHHHHHHHHCCCCCCCCCCEEECCEEEHHHHHHHHHHHCCCCCCCEEEECCCCHHHH
TTIQDVQPQSDEHIKEIKAPLVGTFYTAAGPDEEPFVKPGQSVHAGDVIGIIEAMKLMNE
HHHHHCCCCCHHHHHHHHHCHHHEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
VTADCDGTVKEVAAENGTMVEYGQPLVILN
HCCCCCCHHHHHHHCCCCEEECCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Acetyl-CoA; HCO3-; Proton; acetyl-CoA; ATP [C]

Specific reaction: acetyl-CoA = malonyl-CoA HCO3- + Proton + acetyl-CoA + ATP = malonyl-CoA + phosphate + ADP [C]

General reaction: Ligases; Forming Carbon-Carbon Bonds; acetyl-CoA carboxylase Reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA