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The map label for this gene is fabF [H]

Identifier: 238917640

GI number: 238917640

Start: 1786820

End: 1788052

Strand: Reverse

Name: fabF [H]

Synonym: EUBELI_01719

Alternate gene names: 238917640

Gene position: 1788052-1786820 (Counterclockwise)

Preceding gene: 238917641

Following gene: 238917639

Centisome position: 83.39

GC content: 40.71

Gene sequence:

>1233_bases
ATGAGAAGAGTTGTAATAACAGGTATGGGAGCAGTTACTCCTGTCGGAAACAATGTTAATGATATGTGGGAAGCTGTAAA
GGCTGGTAAATGTGGTATTGGTAAGATAACACATTTTAATACAGAAAACAGTGCAGTCAAGCTTGCTGGTGAAGTAAAAG
GCTTTGACGCAGAGAGTATTGTTGATAAAGCAGAATTAAGGAAAATGGACGATTTCACGATATATGCACTTGCTGCTGCA
GATGAAGCAGTGAAGGATTCAGCTATAGATTTTGGCAAAGAAGACACATTAAGATGTGGTGTTATATTATCAAGTGGAAT
TGGTGGACTTACAACTATACAGAGAGAATGCTTAAGAGGCGAAAGTAAAGGATATGACAGAGTTTCGCCACATTTTGTGC
CAATGTCGATAACTAATATGGCGGCAGGACATGTTGCAATCAGATTTGGACTACATGGAATGTGTACATGTGTTGTTACT
GCATGTGCCAGTGGAACCAATGCTGTTGGAGATGCATTAAGACAGATCAGGGATGGATATCAGGATGTGATTGTGTGCGG
AGGTGCAGAAAGCTGTATAACTGATTTTGGAATTGGTGGTTTTACATCAATGCATGCATTAAGCAAAGCAGAAGATGTCA
ACAGGGCTTCTATTCCGTTTGATAAAGAAAGAAGCGGATTTGTTATGGGAGAAGGAGCAGGTGTGCTTATTCTTGAAGAG
TATGAACATGCACTGAAAAGAGGCGCTAAGATATACTGTGAAATTGCAGGATATGGTTCAACATGTGATGCAAACCACGT
TACAGCCCCTCTCGAAGACGGAAGCATGGCAGCACAGGCAATGACTGAGGCTGTTAAGGATGCAGGAATAAAACCAGAGA
ATATTGATTATATTAATGCACATGGAACAAGTACAAAGCTTAATGATAAGGGCGAGACTAACGCGATAAAGAAGGCATTT
GGAGAACATGCGTACAAGCTTGCGGTAAGCTCAACAAAGTCGATGACAGGACATATGTTAGGTGCAAGTGGTGCTGTTGA
GGCAATTATATCGGCACTTGCTGTAAAGAATGATATAATTCCACCAACCATTAATTATCAGGTGTCGGATGATGACTGTG
ATCTTGATATCGTTCCAAATAAGGCAAGAGAGTCAAGAGTTGATTATGCTATGTCTAATTCACTTGGCTTTGGTGGACAT
AATGCGTCTATCGTGCTTAGAAAGGTGGTGTAA

Upstream 100 bases:

>100_bases
GAAAGCCGGAAGATATTGCAGAAACAGTAGCATTTCTTGCGGGTGACGGAGCACGATACATAACCGGACAGGTACTTTGT
GTAGACGGAGGAATGGCAAT

Downstream 100 bases:

>100_bases
AGATGCAGCTTAATTCAGATGAAATACAGCAGATTCTGCCACACAGATATCCATTTCTATTAGTAGACAGGATAACAGAG
TGTGAACCTGGAAAGAAGGC

Product: 3-oxoacyl-[acyl-carrier-protein] synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MRRVVITGMGAVTPVGNNVNDMWEAVKAGKCGIGKITHFNTENSAVKLAGEVKGFDAESIVDKAELRKMDDFTIYALAAA
DEAVKDSAIDFGKEDTLRCGVILSSGIGGLTTIQRECLRGESKGYDRVSPHFVPMSITNMAAGHVAIRFGLHGMCTCVVT
ACASGTNAVGDALRQIRDGYQDVIVCGGAESCITDFGIGGFTSMHALSKAEDVNRASIPFDKERSGFVMGEGAGVLILEE
YEHALKRGAKIYCEIAGYGSTCDANHVTAPLEDGSMAAQAMTEAVKDAGIKPENIDYINAHGTSTKLNDKGETNAIKKAF
GEHAYKLAVSSTKSMTGHMLGASGAVEAIISALAVKNDIIPPTINYQVSDDDCDLDIVPNKARESRVDYAMSNSLGFGGH
NASIVLRKVV

Sequences:

>Translated_410_residues
MRRVVITGMGAVTPVGNNVNDMWEAVKAGKCGIGKITHFNTENSAVKLAGEVKGFDAESIVDKAELRKMDDFTIYALAAA
DEAVKDSAIDFGKEDTLRCGVILSSGIGGLTTIQRECLRGESKGYDRVSPHFVPMSITNMAAGHVAIRFGLHGMCTCVVT
ACASGTNAVGDALRQIRDGYQDVIVCGGAESCITDFGIGGFTSMHALSKAEDVNRASIPFDKERSGFVMGEGAGVLILEE
YEHALKRGAKIYCEIAGYGSTCDANHVTAPLEDGSMAAQAMTEAVKDAGIKPENIDYINAHGTSTKLNDKGETNAIKKAF
GEHAYKLAVSSTKSMTGHMLGASGAVEAIISALAVKNDIIPPTINYQVSDDDCDLDIVPNKARESRVDYAMSNSLGFGGH
NASIVLRKVV
>Mature_410_residues
MRRVVITGMGAVTPVGNNVNDMWEAVKAGKCGIGKITHFNTENSAVKLAGEVKGFDAESIVDKAELRKMDDFTIYALAAA
DEAVKDSAIDFGKEDTLRCGVILSSGIGGLTTIQRECLRGESKGYDRVSPHFVPMSITNMAAGHVAIRFGLHGMCTCVVT
ACASGTNAVGDALRQIRDGYQDVIVCGGAESCITDFGIGGFTSMHALSKAEDVNRASIPFDKERSGFVMGEGAGVLILEE
YEHALKRGAKIYCEIAGYGSTCDANHVTAPLEDGSMAAQAMTEAVKDAGIKPENIDYINAHGTSTKLNDKGETNAIKKAF
GEHAYKLAVSSTKSMTGHMLGASGAVEAIISALAVKNDIIPPTINYQVSDDDCDLDIVPNKARESRVDYAMSNSLGFGGH
NASIVLRKVV

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=415, Percent_Identity=45.0602409638554, Blast_Score=347, Evalue=1e-95,
Organism=Homo sapiens, GI223972627, Length=147, Percent_Identity=51.0204081632653, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI41872631, Length=435, Percent_Identity=27.1264367816092, Blast_Score=96, Evalue=6e-20,
Organism=Escherichia coli, GI1787337, Length=410, Percent_Identity=50.2439024390244, Blast_Score=377, Evalue=1e-106,
Organism=Escherichia coli, GI1788663, Length=416, Percent_Identity=36.0576923076923, Blast_Score=234, Evalue=8e-63,
Organism=Caenorhabditis elegans, GI71983541, Length=416, Percent_Identity=34.8557692307692, Blast_Score=246, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI71983535, Length=263, Percent_Identity=36.5019011406844, Blast_Score=180, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI212642053, Length=294, Percent_Identity=27.2108843537415, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17550940, Length=419, Percent_Identity=24.582338902148, Blast_Score=98, Evalue=9e-21,
Organism=Saccharomyces cerevisiae, GI6320904, Length=441, Percent_Identity=36.734693877551, Blast_Score=265, Evalue=1e-71,
Organism=Drosophila melanogaster, GI24644341, Length=415, Percent_Identity=42.8915662650602, Blast_Score=313, Evalue=1e-85,
Organism=Drosophila melanogaster, GI19920632, Length=370, Percent_Identity=25.6756756756757, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI221330659, Length=370, Percent_Identity=25.6756756756757, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24581345, Length=444, Percent_Identity=23.4234234234234, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 43317; Mature: 43317

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRVVITGMGAVTPVGNNVNDMWEAVKAGKCGIGKITHFNTENSAVKLAGEVKGFDAESI
CCEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCCEEEEEECCCCCCHHHH
VDKAELRKMDDFTIYALAAADEAVKDSAIDFGKEDTLRCGVILSSGIGGLTTIQRECLRG
HHHHHHHCCCCEEEEEEECCCHHHHHHHHCCCCCCCEEEEEEEECCCCCHHHHHHHHHCC
ESKGYDRVSPHFVPMSITNMAAGHVAIRFGLHGMCTCVVTACASGTNAVGDALRQIRDGY
CCCCCCCCCCCEEEEEHHHHCCCCEEEEECHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
QDVIVCGGAESCITDFGIGGFTSMHALSKAEDVNRASIPFDKERSGFVMGEGAGVLILEE
CEEEEECCCHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCEEEEHH
YEHALKRGAKIYCEIAGYGSTCDANHVTAPLEDGSMAAQAMTEAVKDAGIKPENIDYINA
HHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEC
HGTSTKLNDKGETNAIKKAFGEHAYKLAVSSTKSMTGHMLGASGAVEAIISALAVKNDII
CCCCCCCCCCCCHHHHHHHHHHHHEEEEECCCCHHHHHHCCCCHHHHHHHHHHHHHCCCC
PPTINYQVSDDDCDLDIVPNKARESRVDYAMSNSLGFGGHNASIVLRKVV
CCCEEEEECCCCCCEEECCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECC
>Mature Secondary Structure
MRRVVITGMGAVTPVGNNVNDMWEAVKAGKCGIGKITHFNTENSAVKLAGEVKGFDAESI
CCEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCCEEEEEECCCCCCHHHH
VDKAELRKMDDFTIYALAAADEAVKDSAIDFGKEDTLRCGVILSSGIGGLTTIQRECLRG
HHHHHHHCCCCEEEEEEECCCHHHHHHHHCCCCCCCEEEEEEEECCCCCHHHHHHHHHCC
ESKGYDRVSPHFVPMSITNMAAGHVAIRFGLHGMCTCVVTACASGTNAVGDALRQIRDGY
CCCCCCCCCCCEEEEEHHHHCCCCEEEEECHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
QDVIVCGGAESCITDFGIGGFTSMHALSKAEDVNRASIPFDKERSGFVMGEGAGVLILEE
CEEEEECCCHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCEEEEHH
YEHALKRGAKIYCEIAGYGSTCDANHVTAPLEDGSMAAQAMTEAVKDAGIKPENIDYINA
HHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEC
HGTSTKLNDKGETNAIKKAFGEHAYKLAVSSTKSMTGHMLGASGAVEAIISALAVKNDII
CCCCCCCCCCCCHHHHHHHHHHHHEEEEECCCCHHHHHHCCCCHHHHHHHHHHHHHCCCC
PPTINYQVSDDDCDLDIVPNKARESRVDYAMSNSLGFGGHNASIVLRKVV
CCCEEEEECCCCCCEEECCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]