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The map label for this gene is malP [H]

Identifier: 238917633

GI number: 238917633

Start: 1780291

End: 1782585

Strand: Reverse

Name: malP [H]

Synonym: EUBELI_01712

Alternate gene names: 238917633

Gene position: 1782585-1780291 (Counterclockwise)

Preceding gene: 238917635

Following gene: 238917632

Centisome position: 83.14

GC content: 37.82

Gene sequence:

>2295_bases
ATGGAGGGCAACGATATGCTTAACACTATATGTTTGGAAGAATATGGAAAAGACTTGCACTTATGCAGCAACGAGGAGTG
CTTTCATGCACTTATGAAGCTGGTTGCACAAAAGGGACGTGATAGAATAGTGAAAGACAATGGCAGAAAGGTATACTACA
TTTCTGCAGAGTTCCTTATAGGAAAGCTTTTATCCAATAATCTTATTAATTTAGGAATCTACGATGAAGTTAAGGAAGAA
CTTACACAGGCAGGAAAAAATCTTTCAGATATTGAAGAACTGGAAGTAGAGCCGTCACTTGGTAATGGCGGACTTGGAAG
ACTTGCAGCATGCTTCCTTGATTCGATTGCTAACCTTGGTCTTAATGGTGACGGAATCGGACTTAATTATCATCTTGGAC
TTTTTAAGCAGGTGTTTGAGAATGGAAAGCAGAAGGAAGTGCCTAATCCATGGATTGGTAAGGATAGCTGGCTTGTTCCG
ACAGATGTGACATACACTATCAATTTCGGTGAAATCAGTGTGGTTTCAAGAATGTATGATATCAATGTGTACGGAGAAAA
GAGAACGAATAAGCTTCATTTGTTTGATGTGGAGACAGTTGATGAGAGCATCGTAAAAGGTGACAGCATAGACTTTGATA
AGTCAGATATTGCCAAGAACCTTACACTGTTTCTTTATCCTGATGACAGTGACGAACAGGGAAGGCTTCTTAGAATCTAT
CAGCAGTATTTCATGGTAAGCAATGGAGCAAGGCTTATATTAGATGAGTGCAGGGACAAATGTATTAACACCGGAAAAAC
ATTTAAGAATCTGTCAGACCTTGCAGTTATCCAGATTAACGATACGCATCCGACAATGGTAATCCCGGAGCTTATAAGAC
TTCTTACAGAAAATGGAGATATAGATGGAAGTCCGATAACAATGGACGAAGCAATTGATATTGTATCAAAAAGCTGTGCG
TATACTAATCACACAATCCTTGCTGAAGCCCTTGAAAAATGGCCTGTGGACTATCTTAACAGGGTTGTGCCACAGCTTAT
GCCGATTATAAAAGAGCTTGACAGAAGAGTGCGTAAGAAGTACACAGATAAATCAGTGTATATAATTGACGATAATAATC
TCGTTCACATGGCACACATCGATATTCATTATGGAATGAGCGTCAACGGAGTAGCAAAGCTTCATACTGAGATATTAGAG
AATACAGAGCTTAATAATTTCTATAGGATATATCCAGAGAAATTCAATAACAAAACTAACGGAATCACATTCAGAAGGTG
GCTTATCCACTGTAATAACGGACTTGCGAAATACATTGAGACACTTATCGGAAGTGAATACAGACATGACGCAGAAAAGT
TAAAAGACCTTTTAAAGTTTGCCGGTGATAAAAATGTTTACGATAATCTTCTTGAGATTAAGACAGACAACAAGAGAAAT
CTTGCAGAATACCTTAAGCAGACACAGGGAATAGAGATTAATCCACAGTCAATATACGATATACAGATAAAGCGACTGCA
TGAGTATAAAAGACAGCAGATGAACGCACTGTATATAATATATAAATATTTTGACATCAAGGCAGGCAACATTCCAAAGA
CTCCTGTTACAGTGATATTTGGCGCAAAGGCTGCACCTGCATACACAATTGCGAAGGATATAATTCATCTGATACTTACA
TTGAGTAAGGTTATTGAGGCTGATAAAGATGTAAGTCCTTACCTTAAGGTTGTGCTTGTCCAGAACTACAATGTAACATT
GGCAGAGAAGCTGATTCCTGCATGTGATATATCAGAGCAGATATCACTTGCATCTAAAGAAGCATCAGGAACAGGCAATA
TGAAATTCATGCTCAATGGTGCTGTGACATTAGGAACAATGGATGGTGCTAATGTTGAGATTGCAGAGCTTGTAGGTAAA
GATAATATATATACATTTGGCGCAACAAGTGATGAAGTTATTGCACATTATGAAAAATGTGACTATAACGCAAAGAAGCT
TTATGAGACAGATGCTCTTATAAAAAAATGTGTGGATTTTATAATATCGGATGCTATGCTTCAGGCAGGTGATTCACATA
GTCTTAACAGACTGTATAATGAGATTGTAGGAAAAGACTGGTTTATGGCATTGCTTGACTTACGAAGCTATATAGAAACC
AAAGAAAAGGCTCTCGCAGATTATGATGACAGATATGCGTGGGCAGAAAAAATGCTTGTTAATATTGCAAATGCCGGATT
TTTCTCATCAGACAGAACAATCCGACAGTACAATGAAGATATATGGCATCTTTAA

Upstream 100 bases:

>100_bases
CATAAGGTTCTCCTTAAATATGATAGAATAGTACAAGTTTATCCCATTATAAAGCAAGAGAATTTTTCCAGCAACCCTAT
AATAAAATATAAATACAAGA

Downstream 100 bases:

>100_bases
TATAACTAAATAAGTTGATAATAATTGCCCCGGAAGCTATAATCATTATAAGAGCAAAAGTTCGTGAATGAGGAAGGTTT
CGGGGTAGATTTATGTATAA

Product: starch phosphorylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 764; Mature: 764

Protein sequence:

>764_residues
MEGNDMLNTICLEEYGKDLHLCSNEECFHALMKLVAQKGRDRIVKDNGRKVYYISAEFLIGKLLSNNLINLGIYDEVKEE
LTQAGKNLSDIEELEVEPSLGNGGLGRLAACFLDSIANLGLNGDGIGLNYHLGLFKQVFENGKQKEVPNPWIGKDSWLVP
TDVTYTINFGEISVVSRMYDINVYGEKRTNKLHLFDVETVDESIVKGDSIDFDKSDIAKNLTLFLYPDDSDEQGRLLRIY
QQYFMVSNGARLILDECRDKCINTGKTFKNLSDLAVIQINDTHPTMVIPELIRLLTENGDIDGSPITMDEAIDIVSKSCA
YTNHTILAEALEKWPVDYLNRVVPQLMPIIKELDRRVRKKYTDKSVYIIDDNNLVHMAHIDIHYGMSVNGVAKLHTEILE
NTELNNFYRIYPEKFNNKTNGITFRRWLIHCNNGLAKYIETLIGSEYRHDAEKLKDLLKFAGDKNVYDNLLEIKTDNKRN
LAEYLKQTQGIEINPQSIYDIQIKRLHEYKRQQMNALYIIYKYFDIKAGNIPKTPVTVIFGAKAAPAYTIAKDIIHLILT
LSKVIEADKDVSPYLKVVLVQNYNVTLAEKLIPACDISEQISLASKEASGTGNMKFMLNGAVTLGTMDGANVEIAELVGK
DNIYTFGATSDEVIAHYEKCDYNAKKLYETDALIKKCVDFIISDAMLQAGDSHSLNRLYNEIVGKDWFMALLDLRSYIET
KEKALADYDDRYAWAEKMLVNIANAGFFSSDRTIRQYNEDIWHL

Sequences:

>Translated_764_residues
MEGNDMLNTICLEEYGKDLHLCSNEECFHALMKLVAQKGRDRIVKDNGRKVYYISAEFLIGKLLSNNLINLGIYDEVKEE
LTQAGKNLSDIEELEVEPSLGNGGLGRLAACFLDSIANLGLNGDGIGLNYHLGLFKQVFENGKQKEVPNPWIGKDSWLVP
TDVTYTINFGEISVVSRMYDINVYGEKRTNKLHLFDVETVDESIVKGDSIDFDKSDIAKNLTLFLYPDDSDEQGRLLRIY
QQYFMVSNGARLILDECRDKCINTGKTFKNLSDLAVIQINDTHPTMVIPELIRLLTENGDIDGSPITMDEAIDIVSKSCA
YTNHTILAEALEKWPVDYLNRVVPQLMPIIKELDRRVRKKYTDKSVYIIDDNNLVHMAHIDIHYGMSVNGVAKLHTEILE
NTELNNFYRIYPEKFNNKTNGITFRRWLIHCNNGLAKYIETLIGSEYRHDAEKLKDLLKFAGDKNVYDNLLEIKTDNKRN
LAEYLKQTQGIEINPQSIYDIQIKRLHEYKRQQMNALYIIYKYFDIKAGNIPKTPVTVIFGAKAAPAYTIAKDIIHLILT
LSKVIEADKDVSPYLKVVLVQNYNVTLAEKLIPACDISEQISLASKEASGTGNMKFMLNGAVTLGTMDGANVEIAELVGK
DNIYTFGATSDEVIAHYEKCDYNAKKLYETDALIKKCVDFIISDAMLQAGDSHSLNRLYNEIVGKDWFMALLDLRSYIET
KEKALADYDDRYAWAEKMLVNIANAGFFSSDRTIRQYNEDIWHL
>Mature_764_residues
MEGNDMLNTICLEEYGKDLHLCSNEECFHALMKLVAQKGRDRIVKDNGRKVYYISAEFLIGKLLSNNLINLGIYDEVKEE
LTQAGKNLSDIEELEVEPSLGNGGLGRLAACFLDSIANLGLNGDGIGLNYHLGLFKQVFENGKQKEVPNPWIGKDSWLVP
TDVTYTINFGEISVVSRMYDINVYGEKRTNKLHLFDVETVDESIVKGDSIDFDKSDIAKNLTLFLYPDDSDEQGRLLRIY
QQYFMVSNGARLILDECRDKCINTGKTFKNLSDLAVIQINDTHPTMVIPELIRLLTENGDIDGSPITMDEAIDIVSKSCA
YTNHTILAEALEKWPVDYLNRVVPQLMPIIKELDRRVRKKYTDKSVYIIDDNNLVHMAHIDIHYGMSVNGVAKLHTEILE
NTELNNFYRIYPEKFNNKTNGITFRRWLIHCNNGLAKYIETLIGSEYRHDAEKLKDLLKFAGDKNVYDNLLEIKTDNKRN
LAEYLKQTQGIEINPQSIYDIQIKRLHEYKRQQMNALYIIYKYFDIKAGNIPKTPVTVIFGAKAAPAYTIAKDIIHLILT
LSKVIEADKDVSPYLKVVLVQNYNVTLAEKLIPACDISEQISLASKEASGTGNMKFMLNGAVTLGTMDGANVEIAELVGK
DNIYTFGATSDEVIAHYEKCDYNAKKLYETDALIKKCVDFIISDAMLQAGDSHSLNRLYNEIVGKDWFMALLDLRSYIET
KEKALADYDDRYAWAEKMLVNIANAGFFSSDRTIRQYNEDIWHL

Specific function: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties [

COG id: COG0058

COG function: function code G; Glucan phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycogen phosphorylase family [H]

Homologues:

Organism=Homo sapiens, GI5032009, Length=800, Percent_Identity=36.875, Blast_Score=476, Evalue=1e-134,
Organism=Homo sapiens, GI21361370, Length=796, Percent_Identity=37.6884422110553, Blast_Score=471, Evalue=1e-133,
Organism=Homo sapiens, GI71037379, Length=797, Percent_Identity=38.0175658720201, Blast_Score=469, Evalue=1e-132,
Organism=Homo sapiens, GI255653002, Length=698, Percent_Identity=38.8252148997135, Blast_Score=443, Evalue=1e-124,
Organism=Homo sapiens, GI257900462, Length=563, Percent_Identity=40.3197158081705, Blast_Score=423, Evalue=1e-118,
Organism=Escherichia coli, GI48994936, Length=757, Percent_Identity=41.6116248348745, Blast_Score=538, Evalue=1e-154,
Organism=Escherichia coli, GI2367228, Length=792, Percent_Identity=39.2676767676768, Blast_Score=505, Evalue=1e-144,
Organism=Caenorhabditis elegans, GI17564550, Length=796, Percent_Identity=37.5628140703518, Blast_Score=493, Evalue=1e-139,
Organism=Caenorhabditis elegans, GI32566204, Length=796, Percent_Identity=37.5628140703518, Blast_Score=492, Evalue=1e-139,
Organism=Saccharomyces cerevisiae, GI6325418, Length=808, Percent_Identity=36.0148514851485, Blast_Score=402, Evalue=1e-113,
Organism=Drosophila melanogaster, GI78706832, Length=754, Percent_Identity=40.7161803713528, Blast_Score=510, Evalue=1e-144,
Organism=Drosophila melanogaster, GI24581010, Length=754, Percent_Identity=40.7161803713528, Blast_Score=510, Evalue=1e-144,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011833
- InterPro:   IPR000811 [H]

Pfam domain/function: PF00343 Phosphorylase [H]

EC number: =2.4.1.1 [H]

Molecular weight: Translated: 86870; Mature: 86870

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00102 PHOSPHORYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGNDMLNTICLEEYGKDLHLCSNEECFHALMKLVAQKGRDRIVKDNGRKVYYISAEFLI
CCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCEECCCCEEEEEEHHHHH
GKLLSNNLINLGIYDEVKEELTQAGKNLSDIEELEVEPSLGNGGLGRLAACFLDSIANLG
HHHHHCCCEEECCHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHCC
LNGDGIGLNYHLGLFKQVFENGKQKEVPNPWIGKDSWLVPTDVTYTINFGEISVVSRMYD
CCCCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCEEEEEECCHHEEHHHEEE
INVYGEKRTNKLHLFDVETVDESIVKGDSIDFDKSDIAKNLTLFLYPDDSDEQGRLLRIY
EEEECCCCCCEEEEEEHHHHHHHHHCCCCCCCCHHHHHCCCEEEEECCCCCCCCHHHHHH
QQYFMVSNGARLILDECRDKCINTGKTFKNLSDLAVIQINDTHPTMVIPELIRLLTENGD
HHHHHHCCCCCHHHHHHHHHHHCCCHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHCCCC
IDGSPITMDEAIDIVSKSCAYTNHTILAEALEKWPVDYLNRVVPQLMPIIKELDRRVRKK
CCCCCEEHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
YTDKSVYIIDDNNLVHMAHIDIHYGMSVNGVAKLHTEILENTELNNFYRIYPEKFNNKTN
CCCCEEEEEECCCEEEEEEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEECCHHHCCCCC
GITFRRWLIHCNNGLAKYIETLIGSEYRHDAEKLKDLLKFAGDKNVYDNLLEIKTDNKRN
CEEEEEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHEECCCCCHH
LAEYLKQTQGIEINPQSIYDIQIKRLHEYKRQQMNALYIIYKYFDIKAGNIPKTPVTVIF
HHHHHHHHCCCEECCCCEEHHHHHHHHHHHHHHCCEEEEEEEEEEEECCCCCCCCEEEEE
GAKAAPAYTIAKDIIHLILTLSKVIEADKDVSPYLKVVLVQNYNVTLAEKLIPACDISEQ
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCEEHHHHCCCCCCCHHH
ISLASKEASGTGNMKFMLNGAVTLGTMDGANVEIAELVGKDNIYTFGATSDEVIAHYEKC
HHHHHCCCCCCCCEEEEEECEEEEEECCCCCEEHHHHHCCCCEEEECCCCHHHHHHHHHC
DYNAKKLYETDALIKKCVDFIISDAMLQAGDSHSLNRLYNEIVGKDWFMALLDLRSYIET
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHH
KEKALADYDDRYAWAEKMLVNIANAGFFSSDRTIRQYNEDIWHL
HHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MEGNDMLNTICLEEYGKDLHLCSNEECFHALMKLVAQKGRDRIVKDNGRKVYYISAEFLI
CCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCEECCCCEEEEEEHHHHH
GKLLSNNLINLGIYDEVKEELTQAGKNLSDIEELEVEPSLGNGGLGRLAACFLDSIANLG
HHHHHCCCEEECCHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHCC
LNGDGIGLNYHLGLFKQVFENGKQKEVPNPWIGKDSWLVPTDVTYTINFGEISVVSRMYD
CCCCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCEEEEEECCHHEEHHHEEE
INVYGEKRTNKLHLFDVETVDESIVKGDSIDFDKSDIAKNLTLFLYPDDSDEQGRLLRIY
EEEECCCCCCEEEEEEHHHHHHHHHCCCCCCCCHHHHHCCCEEEEECCCCCCCCHHHHHH
QQYFMVSNGARLILDECRDKCINTGKTFKNLSDLAVIQINDTHPTMVIPELIRLLTENGD
HHHHHHCCCCCHHHHHHHHHHHCCCHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHCCCC
IDGSPITMDEAIDIVSKSCAYTNHTILAEALEKWPVDYLNRVVPQLMPIIKELDRRVRKK
CCCCCEEHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
YTDKSVYIIDDNNLVHMAHIDIHYGMSVNGVAKLHTEILENTELNNFYRIYPEKFNNKTN
CCCCEEEEEECCCEEEEEEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEECCHHHCCCCC
GITFRRWLIHCNNGLAKYIETLIGSEYRHDAEKLKDLLKFAGDKNVYDNLLEIKTDNKRN
CEEEEEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHEECCCCCHH
LAEYLKQTQGIEINPQSIYDIQIKRLHEYKRQQMNALYIIYKYFDIKAGNIPKTPVTVIF
HHHHHHHHCCCEECCCCEEHHHHHHHHHHHHHHCCEEEEEEEEEEEECCCCCCCCEEEEE
GAKAAPAYTIAKDIIHLILTLSKVIEADKDVSPYLKVVLVQNYNVTLAEKLIPACDISEQ
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCEEHHHHCCCCCCCHHH
ISLASKEASGTGNMKFMLNGAVTLGTMDGANVEIAELVGKDNIYTFGATSDEVIAHYEKC
HHHHHCCCCCCCCEEEEEECEEEEEECCCCCEEHHHHHCCCCEEEECCCCHHHHHHHHHC
DYNAKKLYETDALIKKCVDFIISDAMLQAGDSHSLNRLYNEIVGKDWFMALLDLRSYIET
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHH
KEKALADYDDRYAWAEKMLVNIANAGFFSSDRTIRQYNEDIWHL
HHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11463916; 6297760 [H]