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The map label for this gene is yhdH [H]

Identifier: 238917626

GI number: 238917626

Start: 1770069

End: 1771535

Strand: Reverse

Name: yhdH [H]

Synonym: EUBELI_01705

Alternate gene names: 238917626

Gene position: 1771535-1770069 (Counterclockwise)

Preceding gene: 238917627

Following gene: 238917625

Centisome position: 82.62

GC content: 39.54

Gene sequence:

>1467_bases
TTGAAAGAGAGAGAAAAATTCGGCTCGCGACTCGGCTTTATCTTAGTGTCTGCCGGGTGTGCGGTGGGACTTGGTAATGT
GTGGAAATTTCCATACATATGCGGGGAAAATGGTGGTGCGGCATTCGTGCTTATCTATCTTGTATTTCTTGCAATTCTTG
GATTTCCTATTATGTGTGCGGAGTTCACAGTAGGACGAGGAAGCGGTAAAGGTGCTGCAAGGGCATTTGAAGAACTGGAG
ACTAAGGGAAGTAAATGGCATCATTTCAAATGGGTATCGGTAGTAGGAAGCTATGTATTAATGGCTTTCTATACTATGGT
TGCAGGATGGATGCTTTATTATGCATGGCGTGAGGCAAGAGGTTCGTTAGCAGGTTTAGAGCCAGATGAGGTTTCAGGAG
CATTTGGAACTATGCTTTCACAGCCTGGTACAATGACAATCTGGATGATTGTTGCAGTTTTACTTTCGTTTGGTGTATGT
GTATTAGGATTACAGAAGGGCGTTGAGAAGATTACTAAGGTTATGATGTTACTTCTTCTTATCCTTATTGTGGTACTGGC
AGTTCATTCACTTGTACTTCCTAATGCATCAGAAGGTGTTAAATTCTATATGGTGCCTAATCTGGATGCTATTAAATCAA
GAGGTTTAGGACCGGTTATATTTGATGCCATGACACATGCATTCTTTACACTTAGTGTAGGCATTGGCGCAATGGAGATA
TTCGGAAGCTACTTAAAGAAAGACAGAACAATAGGTGGAGAGGCTGTTAATATAATTCTGATTGATACATTTGTTGCTCT
TATGGCAGGATTCATAATTATTCCTGCATGCTTTGCATATGGTGTTGCTCCGGGTGCCGGTCCATCACTTTTATTTATAA
CACTGCCTAACATATTTAATCATATGGCGGGAGGAAGAATATGGGGAACAGCATTCTTTGTATTCATGTCATTTGCAGCA
TTATCAACTGTAATTGCTGTGTTTGAGAACATTATTGCTTTTTATATTGACCTTAAGGGATTTTCAAGGAAAAAGGTTGT
TGCAGGTAATGTTATATTCATGATACTGCTTTCACTTCCTGCTGTATTAGGCTTTAACAAGCTTGCAGCTTTCCAGCCTA
TTGGTCCGGGAAGTTCAATTATGGATCTGGAGGATTTCCTTGTTTCATATAATCTGCTTCCTCTTGGAAGCATGATATTT
GTATTATTCTGTACCAAGAAGAATGGCTGGGGCTGGGAAGGCTTCAGAAAAGAAGCTAATGAAGGAAAAGGTCCTAAGCT
TCCTGAATGGTTAAGATTCTATATGAGTTATATACTTCCGGCTATTATAGTAGTTGTATACCTTAAGGGTTATTATGATA
CATTTAAACCAAGGGGAACAGGTTATCTTGTTGGCTGGATGATATTTGCGTGTGTATTGCTTCTTGCAATATTCGGAATT
GCTAATTATAAGAAGAAAGATGCGTAA

Upstream 100 bases:

>100_bases
TCAGAAGTCAGTGAGAGTATGAAATAATTGGCTGTGAAAATATAGTAATATATGATACAATCTTAATTAATGTAAATATA
TTAACGATGGAGGTTTTATT

Downstream 100 bases:

>100_bases
TCTATGACTAAGAAAGAACTTGCTTTAGAGGTTATAAGAAGATTAAAGGCAGAATATCCGGATTCGGAGTGCAGCCTTGA
TTACGATGATGCCTGGAAAC

Product: neurotransmitter:Na+ symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MKEREKFGSRLGFILVSAGCAVGLGNVWKFPYICGENGGAAFVLIYLVFLAILGFPIMCAEFTVGRGSGKGAARAFEELE
TKGSKWHHFKWVSVVGSYVLMAFYTMVAGWMLYYAWREARGSLAGLEPDEVSGAFGTMLSQPGTMTIWMIVAVLLSFGVC
VLGLQKGVEKITKVMMLLLLILIVVLAVHSLVLPNASEGVKFYMVPNLDAIKSRGLGPVIFDAMTHAFFTLSVGIGAMEI
FGSYLKKDRTIGGEAVNIILIDTFVALMAGFIIIPACFAYGVAPGAGPSLLFITLPNIFNHMAGGRIWGTAFFVFMSFAA
LSTVIAVFENIIAFYIDLKGFSRKKVVAGNVIFMILLSLPAVLGFNKLAAFQPIGPGSSIMDLEDFLVSYNLLPLGSMIF
VLFCTKKNGWGWEGFRKEANEGKGPKLPEWLRFYMSYILPAIIVVVYLKGYYDTFKPRGTGYLVGWMIFACVLLLAIFGI
ANYKKKDA

Sequences:

>Translated_488_residues
MKEREKFGSRLGFILVSAGCAVGLGNVWKFPYICGENGGAAFVLIYLVFLAILGFPIMCAEFTVGRGSGKGAARAFEELE
TKGSKWHHFKWVSVVGSYVLMAFYTMVAGWMLYYAWREARGSLAGLEPDEVSGAFGTMLSQPGTMTIWMIVAVLLSFGVC
VLGLQKGVEKITKVMMLLLLILIVVLAVHSLVLPNASEGVKFYMVPNLDAIKSRGLGPVIFDAMTHAFFTLSVGIGAMEI
FGSYLKKDRTIGGEAVNIILIDTFVALMAGFIIIPACFAYGVAPGAGPSLLFITLPNIFNHMAGGRIWGTAFFVFMSFAA
LSTVIAVFENIIAFYIDLKGFSRKKVVAGNVIFMILLSLPAVLGFNKLAAFQPIGPGSSIMDLEDFLVSYNLLPLGSMIF
VLFCTKKNGWGWEGFRKEANEGKGPKLPEWLRFYMSYILPAIIVVVYLKGYYDTFKPRGTGYLVGWMIFACVLLLAIFGI
ANYKKKDA
>Mature_488_residues
MKEREKFGSRLGFILVSAGCAVGLGNVWKFPYICGENGGAAFVLIYLVFLAILGFPIMCAEFTVGRGSGKGAARAFEELE
TKGSKWHHFKWVSVVGSYVLMAFYTMVAGWMLYYAWREARGSLAGLEPDEVSGAFGTMLSQPGTMTIWMIVAVLLSFGVC
VLGLQKGVEKITKVMMLLLLILIVVLAVHSLVLPNASEGVKFYMVPNLDAIKSRGLGPVIFDAMTHAFFTLSVGIGAMEI
FGSYLKKDRTIGGEAVNIILIDTFVALMAGFIIIPACFAYGVAPGAGPSLLFITLPNIFNHMAGGRIWGTAFFVFMSFAA
LSTVIAVFENIIAFYIDLKGFSRKKVVAGNVIFMILLSLPAVLGFNKLAAFQPIGPGSSIMDLEDFLVSYNLLPLGSMIF
VLFCTKKNGWGWEGFRKEANEGKGPKLPEWLRFYMSYILPAIIVVVYLKGYYDTFKPRGTGYLVGWMIFACVLLLAIFGI
ANYKKKDA

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI21361581, Length=382, Percent_Identity=24.6073298429319, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI4507043, Length=384, Percent_Identity=26.5625, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI171184408, Length=403, Percent_Identity=24.317617866005, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI171184406, Length=403, Percent_Identity=24.317617866005, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI171184404, Length=403, Percent_Identity=24.317617866005, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI7657587, Length=532, Percent_Identity=22.3684210526316, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI58219014, Length=308, Percent_Identity=28.2467532467532, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI289191351, Length=394, Percent_Identity=26.9035532994924, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI4557046, Length=394, Percent_Identity=26.9035532994924, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI188528618, Length=380, Percent_Identity=22.8947368421053, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI289191377, Length=394, Percent_Identity=26.9035532994924, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI33354281, Length=301, Percent_Identity=25.5813953488372, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI194018524, Length=304, Percent_Identity=25, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI197276623, Length=403, Percent_Identity=25.0620347394541, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI54607094, Length=403, Percent_Identity=25.0620347394541, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI4507041, Length=389, Percent_Identity=25.9640102827763, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI51468073, Length=300, Percent_Identity=22, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI5032097, Length=393, Percent_Identity=25.9541984732824, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI6005715, Length=413, Percent_Identity=23.4866828087167, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI134304856, Length=348, Percent_Identity=26.1494252873563, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI11181770, Length=298, Percent_Identity=24.496644295302, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI67782317, Length=394, Percent_Identity=23.8578680203046, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI67782313, Length=394, Percent_Identity=23.8578680203046, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI67782315, Length=394, Percent_Identity=23.8578680203046, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI218563756, Length=387, Percent_Identity=25.8397932816537, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI21361693, Length=113, Percent_Identity=36.283185840708, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI197276625, Length=121, Percent_Identity=35.5371900826446, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI300360519, Length=202, Percent_Identity=24.2574257425743, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI12408638, Length=275, Percent_Identity=25.0909090909091, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI92859670, Length=78, Percent_Identity=43.5897435897436, Blast_Score=70, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI25146584, Length=546, Percent_Identity=22.8937728937729, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17555248, Length=395, Percent_Identity=23.2911392405063, Blast_Score=101, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17554804, Length=398, Percent_Identity=25.1256281407035, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71995588, Length=422, Percent_Identity=23.4597156398104, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI133952791, Length=219, Percent_Identity=25.1141552511416, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17535731, Length=127, Percent_Identity=33.0708661417323, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17569475, Length=408, Percent_Identity=21.078431372549, Blast_Score=65, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI71998244, Length=298, Percent_Identity=23.1543624161074, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24762620, Length=530, Percent_Identity=25.4716981132075, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI45551183, Length=439, Percent_Identity=25.0569476082005, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI45550877, Length=397, Percent_Identity=24.9370277078086, Blast_Score=119, Evalue=7e-27,
Organism=Drosophila melanogaster, GI17136952, Length=391, Percent_Identity=23.5294117647059, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI281364394, Length=394, Percent_Identity=23.8578680203046, Blast_Score=115, Evalue=1e-25,
Organism=Drosophila melanogaster, GI28574704, Length=394, Percent_Identity=23.8578680203046, Blast_Score=115, Evalue=1e-25,
Organism=Drosophila melanogaster, GI17136950, Length=394, Percent_Identity=23.8578680203046, Blast_Score=115, Evalue=1e-25,
Organism=Drosophila melanogaster, GI28574702, Length=394, Percent_Identity=23.8578680203046, Blast_Score=115, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24661428, Length=545, Percent_Identity=25.6880733944954, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI221329674, Length=412, Percent_Identity=23.3009708737864, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24639514, Length=412, Percent_Identity=23.3009708737864, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24652942, Length=306, Percent_Identity=25.8169934640523, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI45551088, Length=306, Percent_Identity=25.8169934640523, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24639516, Length=432, Percent_Identity=22.2222222222222, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI19921936, Length=342, Percent_Identity=26.3157894736842, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI281363702, Length=523, Percent_Identity=22.1797323135755, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI281364136, Length=409, Percent_Identity=23.4718826405868, Blast_Score=96, Evalue=7e-20,
Organism=Drosophila melanogaster, GI281363700, Length=299, Percent_Identity=24.4147157190635, Blast_Score=96, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24582567, Length=414, Percent_Identity=24.1545893719807, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI19921352, Length=321, Percent_Identity=24.9221183800623, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24584353, Length=321, Percent_Identity=24.9221183800623, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24655079, Length=303, Percent_Identity=22.4422442244224, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI281365034, Length=320, Percent_Identity=24.6875, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24654186, Length=196, Percent_Identity=26.530612244898, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 53365; Mature: 53365

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS00610 NA_NEUROTRAN_SYMP_1 ; PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEREKFGSRLGFILVSAGCAVGLGNVWKFPYICGENGGAAFVLIYLVFLAILGFPIMCA
CCCHHHHHHHHHHHHHHCCHHHCCCCHHCCCEEECCCCCHHHHHHHHHHHHHHCCHHHHH
EFTVGRGSGKGAARAFEELETKGSKWHHFKWVSVVGSYVLMAFYTMVAGWMLYYAWREAR
HEECCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GSLAGLEPDEVSGAFGTMLSQPGTMTIWMIVAVLLSFGVCVLGLQKGVEKITKVMMLLLL
CCCCCCCCHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILIVVLAVHSLVLPNASEGVKFYMVPNLDAIKSRGLGPVIFDAMTHAFFTLSVGIGAMEI
HHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHH
FGSYLKKDRTIGGEAVNIILIDTFVALMAGFIIIPACFAYGVAPGAGPSLLFITLPNIFN
HHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECHHHHH
HMAGGRIWGTAFFVFMSFAALSTVIAVFENIIAFYIDLKGFSRKKVVAGNVIFMILLSLP
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHH
AVLGFNKLAAFQPIGPGSSIMDLEDFLVSYNLLPLGSMIFVLFCTKKNGWGWEGFRKEAN
HHHCHHHHHHCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHEEECCCCCCCHHHHHHCC
EGKGPKLPEWLRFYMSYILPAIIVVVYLKGYYDTFKPRGTGYLVGWMIFACVLLLAIFGI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
ANYKKKDA
CCCCCCCC
>Mature Secondary Structure
MKEREKFGSRLGFILVSAGCAVGLGNVWKFPYICGENGGAAFVLIYLVFLAILGFPIMCA
CCCHHHHHHHHHHHHHHCCHHHCCCCHHCCCEEECCCCCHHHHHHHHHHHHHHCCHHHHH
EFTVGRGSGKGAARAFEELETKGSKWHHFKWVSVVGSYVLMAFYTMVAGWMLYYAWREAR
HEECCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GSLAGLEPDEVSGAFGTMLSQPGTMTIWMIVAVLLSFGVCVLGLQKGVEKITKVMMLLLL
CCCCCCCCHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILIVVLAVHSLVLPNASEGVKFYMVPNLDAIKSRGLGPVIFDAMTHAFFTLSVGIGAMEI
HHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHH
FGSYLKKDRTIGGEAVNIILIDTFVALMAGFIIIPACFAYGVAPGAGPSLLFITLPNIFN
HHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECHHHHH
HMAGGRIWGTAFFVFMSFAALSTVIAVFENIIAFYIDLKGFSRKKVVAGNVIFMILLSLP
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHH
AVLGFNKLAAFQPIGPGSSIMDLEDFLVSYNLLPLGSMIFVLFCTKKNGWGWEGFRKEAN
HHHCHHHHHHCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHEEECCCCCCCHHHHHHCC
EGKGPKLPEWLRFYMSYILPAIIVVVYLKGYYDTFKPRGTGYLVGWMIFACVLLLAIFGI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
ANYKKKDA
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]