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The map label for this gene is lpa-14 [H]

Identifier: 238917607

GI number: 238917607

Start: 1749193

End: 1749885

Strand: Reverse

Name: lpa-14 [H]

Synonym: EUBELI_01686

Alternate gene names: 238917607

Gene position: 1749885-1749193 (Counterclockwise)

Preceding gene: 238917608

Following gene: 238917606

Centisome position: 81.61

GC content: 34.78

Gene sequence:

>693_bases
ATGATTATGATGATATTTGTGACAACGACAGATGCATTAGCAGATGAAAAGTTATATGAAAAGGCCTATTCGCTTATTCC
GGAATACAGGAAAGTTAAGGCTGATAAGATGAAAATGCGTGAAAATAAGCTGCAAACTGTGACGGCAGGACTACTTCTTA
ATTATGCAGTAGGAAAATGGTCTATAAAAAAAGGAGAAAAGGATTATAAAACAGATGAAATTCTATATGAGACGGTGGAT
ATTATTTCTGTGATTGAAGCAAATAATCAGTACTTTGATTATGAAATAGCATATAATTCGCAAGGGAAACCTTATTTTTT
ATCAAATTGTGAAATTTTTTTCAATATCTCACATTCGTCTAATTATGTAGCGTGTGTAATAGGCGACAGACCGGTAGGAA
TTGACATTGAAAAAACCCGTGAAGGTAGACAAAATCTGGCAAAACGTTTCTTTGACATATCAGAAGCAGAATGGATTAAA
GAGTGTGATAGTGACGAAAGATTCTTCAGAATATGGACACTTAAAGAGGCATATGGCAAGGCTACAGGCCAAGGTGTGCT
TGACATTTTAGGTAAAATAGTTTATAGATTAGAGAAAGGGAAAATGTCGGCGTATATGTGCGGATTTCCCCAGAATTTCA
CTATTGTAGAAAAGGAAGTTGATGGATTCAGATTATCAGCAATACAATTGTGA

Upstream 100 bases:

>100_bases
TTAAGAAATGGTGAGACATTGATTAAATCAGGTGATATAGTATTCGTGTTCTCAAAGCGTTATATGGCAGATGCACAGAC
AATAAGCGTATAGATGGTGA

Downstream 100 bases:

>100_bases
AATCCATATCCAACTATTCATTATACAGTTGAAAAATATTAATAATGGCGGTATAATATAGAACATGTATATCTATTGAA
AAGCCTAAGGAGGGTTTATG

Product: hypothetical protein

Products: adenosine 3',5'-bisphosphate [C]

Alternate protein names: Lipopeptide antibiotics iturin A and surfactin biosynthesis protein [H]

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MIMMIFVTTTDALADEKLYEKAYSLIPEYRKVKADKMKMRENKLQTVTAGLLLNYAVGKWSIKKGEKDYKTDEILYETVD
IISVIEANNQYFDYEIAYNSQGKPYFLSNCEIFFNISHSSNYVACVIGDRPVGIDIEKTREGRQNLAKRFFDISEAEWIK
ECDSDERFFRIWTLKEAYGKATGQGVLDILGKIVYRLEKGKMSAYMCGFPQNFTIVEKEVDGFRLSAIQL

Sequences:

>Translated_230_residues
MIMMIFVTTTDALADEKLYEKAYSLIPEYRKVKADKMKMRENKLQTVTAGLLLNYAVGKWSIKKGEKDYKTDEILYETVD
IISVIEANNQYFDYEIAYNSQGKPYFLSNCEIFFNISHSSNYVACVIGDRPVGIDIEKTREGRQNLAKRFFDISEAEWIK
ECDSDERFFRIWTLKEAYGKATGQGVLDILGKIVYRLEKGKMSAYMCGFPQNFTIVEKEVDGFRLSAIQL
>Mature_230_residues
MIMMIFVTTTDALADEKLYEKAYSLIPEYRKVKADKMKMRENKLQTVTAGLLLNYAVGKWSIKKGEKDYKTDEILYETVD
IISVIEANNQYFDYEIAYNSQGKPYFLSNCEIFFNISHSSNYVACVIGDRPVGIDIEKTREGRQNLAKRFFDISEAEWIK
ECDSDERFFRIWTLKEAYGKATGQGVLDILGKIVYRLEKGKMSAYMCGFPQNFTIVEKEVDGFRLSAIQL

Specific function: May activate the peptidyl carrier protein (PCP) domains of surfactin synthetase SRF1/2/3 and iturin A synthetase, by transferring the 4'-phosphopantetheinyl moiety of coenzyme A (CoA) to a serine residue. Required for the coproduction of the lipopeptide a

COG id: COG2091

COG function: function code H; Phosphopantetheinyl transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. Gsp/sfp/hetI/acpT family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17564880, Length=136, Percent_Identity=30.8823529411765, Blast_Score=68, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008278
- InterPro:   IPR004568 [H]

Pfam domain/function: PF01648 ACPS [H]

EC number: NA

Molecular weight: Translated: 26595; Mature: 26595

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIMMIFVTTTDALADEKLYEKAYSLIPEYRKVKADKMKMRENKLQTVTAGLLLNYAVGKW
CEEEEEEECCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
SIKKGEKDYKTDEILYETVDIISVIEANNQYFDYEIAYNSQGKPYFLSNCEIFFNISHSS
EECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCEEEEECCEEEEEEECCC
NYVACVIGDRPVGIDIEKTREGRQNLAKRFFDISEAEWIKECDSDERFFRIWTLKEAYGK
CEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEEEEEHHHHCC
ATGQGVLDILGKIVYRLEKGKMSAYMCGFPQNFTIVEKEVDGFRLSAIQL
CCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEECCCCEEEEEEEC
>Mature Secondary Structure
MIMMIFVTTTDALADEKLYEKAYSLIPEYRKVKADKMKMRENKLQTVTAGLLLNYAVGKW
CEEEEEEECCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
SIKKGEKDYKTDEILYETVDIISVIEANNQYFDYEIAYNSQGKPYFLSNCEIFFNISHSS
EECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCEEEEECCEEEEEEECCC
NYVACVIGDRPVGIDIEKTREGRQNLAKRFFDISEAEWIKECDSDERFFRIWTLKEAYGK
CEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEEEEEHHHHCC
ATGQGVLDILGKIVYRLEKGKMSAYMCGFPQNFTIVEKEVDGFRLSAIQL
CCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEECCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coenzyme A; apo-[acyl carrier protein] [C]

Specific reaction: Coenzyme A + apo-[acyl carrier protein] = adenosine 3',5'-bisphosphate + [acyl carrier protein] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8939709 [H]