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The map label for this gene is mutT [C]

Identifier: 238917430

GI number: 238917430

Start: 1563731

End: 1564189

Strand: Reverse

Name: mutT [C]

Synonym: EUBELI_01508

Alternate gene names: 238917430

Gene position: 1564189-1563731 (Counterclockwise)

Preceding gene: 238917431

Following gene: 238917428

Centisome position: 72.95

GC content: 39.65

Gene sequence:

>459_bases
ATGCCTAATTACATAATGGATTTAAGGAAGCTCGTAGGGCACAGGACACTTATGCAGTGTGCTGCGAGTATAATAATAGT
GAATGAGAATAACCAGATTCTTTTAGGAAAGAGGACGGATAATCACAAATGGGGATATGCCGGGGGTTCTATTGAACTTG
ATGAGAAGGTAGAGGATTGTGCAAGGAGAGAACTGTATGAGGAGACAGGTCTTGTTGCAGATGAGATAGAGTTCTTTATG
GTTAATTCAGGACCAGAGGTGCATTATATATATCCGAATGGAGACGAGGTGTCTAATATAGAGATTATATATGTGTGCAG
GCGGTATCATGGAGAATTAAAGAGACAGGAGGAAGAGATTGAGGAACTGAGATTCTTTAATCTGGAGGATATAGATATTG
ATAACATTTCACCACCGATAAGACCAGTGGTGAAACGGTTCATAGAACAGTATTCTTAA

Upstream 100 bases:

>100_bases
ATGGATGAACCTTCATCGGCATTAGATACATATAGTGAAAATGCAGTACTTGAAGACTTCGAATCAAGAGCAACATTAAA
CAGAAAGCCGAGGAAACCAC

Downstream 100 bases:

>100_bases
CAAATGCTGAGCAGATGAAACACATTTTTTCTGAATTCAATAAGCCCGTCATCGCGCATTTTACCTAGCTCTTTAGAAAG
TGCCGTGCGGTCGACATTAA

Product: hypothetical protein

Products: 8-Oxo-Dgmp; Pyrophosphate. [C]

Alternate protein names: MutT/Nudix Family Protein; ADP-Ribose Pyrophosphatase; NTP Pyrophosphohydrolase; MutT/NUDIX Family Protein; Phosphohydrolase; MutT/Nudix Family Phosphohydrolase; Nucleoside Polyphosphate Hydrolase; Hydrolase NUDIX Family; MutT/NUDIX Family Phosphohydrolase; UDP-Sugar Hydrolase; NUDIX Domain-Containing Protein; Mut-Like Protein; Phosphohydrolase MutT/Nudix Family; NUDIX-Like Protein; Nudix Superfamily Hydrolase; Mutt/Nudix Family Protein; Ntp Pyrophosphohydrolase

Number of amino acids: Translated: 152; Mature: 151

Protein sequence:

>152_residues
MPNYIMDLRKLVGHRTLMQCAASIIIVNENNQILLGKRTDNHKWGYAGGSIELDEKVEDCARRELYEETGLVADEIEFFM
VNSGPEVHYIYPNGDEVSNIEIIYVCRRYHGELKRQEEEIEELRFFNLEDIDIDNISPPIRPVVKRFIEQYS

Sequences:

>Translated_152_residues
MPNYIMDLRKLVGHRTLMQCAASIIIVNENNQILLGKRTDNHKWGYAGGSIELDEKVEDCARRELYEETGLVADEIEFFM
VNSGPEVHYIYPNGDEVSNIEIIYVCRRYHGELKRQEEEIEELRFFNLEDIDIDNISPPIRPVVKRFIEQYS
>Mature_151_residues
PNYIMDLRKLVGHRTLMQCAASIIIVNENNQILLGKRTDNHKWGYAGGSIELDEKVEDCARRELYEETGLVADEIEFFMV
NSGPEVHYIYPNGDEVSNIEIIYVCRRYHGELKRQEEEIEELRFFNLEDIDIDNISPPIRPVVKRFIEQYS

Specific function: Involved In The Go System Responsible For Removing An Oxidatively Damaged Form Of Guanine (7,8-Dihydro-8-Oxoguanine) From DNA And The Nucleotide Pool. 8-Oxo-Dgtp Is Inserted Opposite Da And Dc Residues Of Template DNA With Almost Equal Efficiency Thus Le

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.6.1.- [C]

Molecular weight: Translated: 17824; Mature: 17693

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNYIMDLRKLVGHRTLMQCAASIIIVNENNQILLGKRTDNHKWGYAGGSIELDEKVEDC
CCHHHHHHHHHHHHHHHHHHHCEEEEECCCCEEEEEECCCCCCCCCCCCCEEHHHHHHHH
ARRELYEETGLVADEIEFFMVNSGPEVHYIYPNGDEVSNIEIIYVCRRYHGELKRQEEEI
HHHHHHHHHCCCHHCEEEEEECCCCEEEEECCCCCCCCCEEEEEEEHHHHHHHHHHHHHH
EELRFFNLEDIDIDNISPPIRPVVKRFIEQYS
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
PNYIMDLRKLVGHRTLMQCAASIIIVNENNQILLGKRTDNHKWGYAGGSIELDEKVEDC
CHHHHHHHHHHHHHHHHHHHCEEEEECCCCEEEEEECCCCCCCCCCCCCEEHHHHHHHH
ARRELYEETGLVADEIEFFMVNSGPEVHYIYPNGDEVSNIEIIYVCRRYHGELKRQEEEI
HHHHHHHHHCCCHHCEEEEEECCCCEEEEECCCCCCCCCEEEEEEEHHHHHHHHHHHHHH
EELRFFNLEDIDIDNISPPIRPVVKRFIEQYS
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 8-Oxo-Dgtp; H2O [C]

Specific reaction: 8-Oxo-Dgtp + H2O = 8-Oxo-Dgmp + Pyrophosphate. [C]

General reaction: Hydrolase; Acting on acid anhydrides; In phosphorus-containing anhydrides [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA