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The map label for this gene is yybE [H]

Identifier: 238917409

GI number: 238917409

Start: 1542611

End: 1543510

Strand: Reverse

Name: yybE [H]

Synonym: EUBELI_01487

Alternate gene names: 238917409

Gene position: 1543510-1542611 (Counterclockwise)

Preceding gene: 238917411

Following gene: 238917408

Centisome position: 71.99

GC content: 39.0

Gene sequence:

>900_bases
ATGAATATATATAATCTGAGATATTTCGTTACACTTGCAAGAATACGCCAGTACACGAAGGCGGCAGAGGAATTATGCAT
TACACAGCCGAGTCTTAGTCATGCAATTTCACAGATGGAAAAGGAACTTGGTGTTAAACTCTTTGAAAAAAACGGACATA
AGATAACTCTGACTCAATTCGGAGAGGAGTTTCTTTCTTATGCAGAAAAGACTCTTGATGTGTTAGATGATGGAATCGCT
TCTATTAAAAGAAGTGCAATGGGAAATGGAACGATAAGATTAGGACTTGTAAGACCATTGGGAATAAGCTATGTCCCTCG
GATGGCGGCAGCATTTATAAAGAAGAATCCGAAGCTTGATATAGATTTTACGTTTCACACAGATGTTACGGGCAGGCTGC
TTGACGATATGCAGCTTGGGAAGTATGATTTGTTGTTCTGTTCCAAGCCATCAGAAGAATATCATTTTACGGCTGAGCCC
GTTATGAAGCAGAGACTGGTGCTTATTACTCCCAAAGGACATCCGCTGGCTAAGAAAAGGAAAAGGAGCATTAATCTTGC
AGAGACAGCCGGGTATTCATATGTATGTTTTGACAAGAACTCTGGAATAAGAAGCATATTTGATGAAATGTTGAAAAGAT
CGGACATAACAGTAAAGGTTGCATATGAAACTGAGGAAGATCAGGTTATTGCCGGGCTGGTTGCTAGTGGATTCGGAATA
GCGGTAGTTCCATATATGGATATATTGGAAAAGATGTCTGTAGAAATATTTGAAATCGAGTCACCTGAATATGAGAGAAG
CTTTTATATGGTTAATGATAATAGTACATACATGTCTCCTGCTGTAGAGACGTTCAGGAACTTTGTTATAGAGAATACAA
GTGTTTTAACGGCTTTGTAG

Upstream 100 bases:

>100_bases
ATTATTAATTAATAACAAATGAATAATTTTAATGAAATTATAGATTTTGTCTATAGAACTGTTTATAATTAAGATAATAA
ATGTGCTTAGGAGGCTGTCT

Downstream 100 bases:

>100_bases
AGATTAATATAATTAATGAATAACCGGATATATCTTAATTAAATGACAAATTTGTAGAAAAATTAACAGATTTTATTGAC
ATATTTTTGACAAATTTTAA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MNIYNLRYFVTLARIRQYTKAAEELCITQPSLSHAISQMEKELGVKLFEKNGHKITLTQFGEEFLSYAEKTLDVLDDGIA
SIKRSAMGNGTIRLGLVRPLGISYVPRMAAAFIKKNPKLDIDFTFHTDVTGRLLDDMQLGKYDLLFCSKPSEEYHFTAEP
VMKQRLVLITPKGHPLAKKRKRSINLAETAGYSYVCFDKNSGIRSIFDEMLKRSDITVKVAYETEEDQVIAGLVASGFGI
AVVPYMDILEKMSVEIFEIESPEYERSFYMVNDNSTYMSPAVETFRNFVIENTSVLTAL

Sequences:

>Translated_299_residues
MNIYNLRYFVTLARIRQYTKAAEELCITQPSLSHAISQMEKELGVKLFEKNGHKITLTQFGEEFLSYAEKTLDVLDDGIA
SIKRSAMGNGTIRLGLVRPLGISYVPRMAAAFIKKNPKLDIDFTFHTDVTGRLLDDMQLGKYDLLFCSKPSEEYHFTAEP
VMKQRLVLITPKGHPLAKKRKRSINLAETAGYSYVCFDKNSGIRSIFDEMLKRSDITVKVAYETEEDQVIAGLVASGFGI
AVVPYMDILEKMSVEIFEIESPEYERSFYMVNDNSTYMSPAVETFRNFVIENTSVLTAL
>Mature_299_residues
MNIYNLRYFVTLARIRQYTKAAEELCITQPSLSHAISQMEKELGVKLFEKNGHKITLTQFGEEFLSYAEKTLDVLDDGIA
SIKRSAMGNGTIRLGLVRPLGISYVPRMAAAFIKKNPKLDIDFTFHTDVTGRLLDDMQLGKYDLLFCSKPSEEYHFTAEP
VMKQRLVLITPKGHPLAKKRKRSINLAETAGYSYVCFDKNSGIRSIFDEMLKRSDITVKVAYETEEDQVIAGLVASGFGI
AVVPYMDILEKMSVEIFEIESPEYERSFYMVNDNSTYMSPAVETFRNFVIENTSVLTAL

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=297, Percent_Identity=26.9360269360269, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI145693105, Length=291, Percent_Identity=25.085910652921, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788748, Length=301, Percent_Identity=22.9235880398671, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1787806, Length=253, Percent_Identity=25.6916996047431, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1790399, Length=251, Percent_Identity=26.2948207171315, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI157672245, Length=294, Percent_Identity=21.4285714285714, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788887, Length=301, Percent_Identity=23.9202657807309, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1788481, Length=293, Percent_Identity=22.5255972696246, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1787530, Length=257, Percent_Identity=24.9027237354086, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87082132, Length=299, Percent_Identity=23.0769230769231, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1790208, Length=285, Percent_Identity=23.1578947368421, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1787601, Length=273, Percent_Identity=22.3443223443223, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87081904, Length=215, Percent_Identity=22.3255813953488, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788297, Length=253, Percent_Identity=24.901185770751, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789204, Length=248, Percent_Identity=21.3709677419355, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787589, Length=139, Percent_Identity=30.9352517985612, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1786448, Length=135, Percent_Identity=30.3703703703704, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33901; Mature: 33901

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIYNLRYFVTLARIRQYTKAAEELCITQPSLSHAISQMEKELGVKLFEKNGHKITLTQF
CCEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEECCCCEEEHHHH
GEEFLSYAEKTLDVLDDGIASIKRSAMGNGTIRLGLVRPLGISYVPRMAAAFIKKNPKLD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCEE
IDFTFHTDVTGRLLDDMQLGKYDLLFCSKPSEEYHFTAEPVMKQRLVLITPKGHPLAKKR
EEEEEECCCHHHHHHHCCCCCEEEEEECCCCCCCEEECCHHHHCCEEEECCCCCCHHHHH
KRSINLAETAGYSYVCFDKNSGIRSIFDEMLKRSDITVKVAYETEEDQVIAGLVASGFGI
HCCCCHHHHCCCEEEEEECCCCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHCCCCE
AVVPYMDILEKMSVEIFEIESPEYERSFYMVNDNSTYMSPAVETFRNFVIENTSVLTAL
EEHHHHHHHHHCCEEEEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEC
>Mature Secondary Structure
MNIYNLRYFVTLARIRQYTKAAEELCITQPSLSHAISQMEKELGVKLFEKNGHKITLTQF
CCEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEECCCCEEEHHHH
GEEFLSYAEKTLDVLDDGIASIKRSAMGNGTIRLGLVRPLGISYVPRMAAAFIKKNPKLD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCEE
IDFTFHTDVTGRLLDDMQLGKYDLLFCSKPSEEYHFTAEPVMKQRLVLITPKGHPLAKKR
EEEEEECCCHHHHHHHCCCCCEEEEEECCCCCCCEEECCHHHHCCEEEECCCCCCHHHHH
KRSINLAETAGYSYVCFDKNSGIRSIFDEMLKRSDITVKVAYETEEDQVIAGLVASGFGI
HCCCCHHHHCCCEEEEEECCCCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHCCCCE
AVVPYMDILEKMSVEIFEIESPEYERSFYMVNDNSTYMSPAVETFRNFVIENTSVLTAL
EEHHHHHHHHHCCEEEEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]