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The map label for this gene is atpA [H]

Identifier: 238917404

GI number: 238917404

Start: 1538823

End: 1540328

Strand: Reverse

Name: atpA [H]

Synonym: EUBELI_01482

Alternate gene names: 238917404

Gene position: 1540328-1538823 (Counterclockwise)

Preceding gene: 238917405

Following gene: 238917403

Centisome position: 71.84

GC content: 40.9

Gene sequence:

>1506_bases
GTGACCCCTGTGGGCGCAATTAGTGCAACAGATATTATCTCCATTATCCAGAGTGAGATTGAGAATTTCAATTGGGATGA
AGCAAGCCGTGAGACCGGTAATGTAATATGGGTCGGTGATGGAATTGCTACTGTATACGGTATTGACCATGCAATGTATG
GTGAAATCGTAGTATTTGATAATGGAGTAAAAGGAATGGTTCAGGATATCCGTGAGAATGAGATAGGTGTTATCTTGTTT
GGCAGGGATACAGGAATCAAAGAAGGAACTAAGGTTGTAAGAACCAAGAAAAAAGCCGGAATTCCGGTAGGCAGCGCATT
TGTAGGAAGAGTAATCAATGCACTTGGCGAGCCTATTGATGGAAAAGGCGATATTAAAGAAGAAGATTACAGACCAATTG
AGGAAGATGCTCCTGGTATCGTAGACCGTAAGTCTGTAAGCACACCAATGGAAACAGGAATACTTTCAATTGATTCAATG
TTCCCAATTGGTCGTGGACAGCGAGAACTTATCATTGGTGACCGTCAGACTGGTAAGACATCAATTGCCACAGATACAAT
TATTAACCAGAAAGGTAAAGGTGTTATCTGTGTGTATGTTGCAATCGGACAGAAGGCATCTACAGTTGCCAAGGTTGTAT
CAACACTTACTAAGCATGGTGCAATGGATTATTCAATTGTTGTATCTTCAACAGCGAGTGATCCCGCATCACTTCAGTAT
ATAGCTCCATATGCAGGTACTGCAATGGCAGAGCATTTCATGCATCAGGGAAAAGATGTTCTTATTGTATATGATGATTT
GAGCAAACATGCGGTAGCGTATAGAGCACTTTCCCTTCTGCTTGAAAGATCACCTGGACGAGAGGCTTATCCTGGAGATG
TATTCTATCTTCATTCAAGACTTCTTGAAAGATCAAGCCGTTTAAGTGATGCGTTAGGTGGAGGCTCAATAACAGCACTT
CCTATAATAGAGACACAGGCTGGTGATGTATCAGCATATATTCCAACAAATGTTATCTCTATCACAGATGGTCAGATATT
CCTTGAAACTAATTTGTTTAATTCAGGTATGAGACCAGCCGTTAATGTAGGTCTTTCGGTTTCACGAGTTGGTGGTGCAG
CCCAGACTAAGGCAATGAAGAAGGCATCAGGAAGCATAAGAATTGACCTTGCACAGTACAGAGAGATGGAAGTATTTACA
CAGTTTGCATCAGATCTTGATGATGCAACTAAGGCACAGTTACAGCACGGAAAAGCCCTTATGGAGCTTTTAAAGCAGCC
ACTCTGCCATCCACTTTCAATGCATGAGCAGGTTATGACACTTGTTATGGCTAACAACGGCGTATTTGATGAGATACCTA
CTAAGGAAGTTAAGAAACACCAGACAGAATTACTTGAATTCATAGATCTCAAGCATCCTGAAATAGGAAAGCAGATTGAA
GATGAGAAAGAGATTAATGATGAGCTGGTTAAGAATATTCTGGAAGCAGTAAAAGAATTTGCATAA

Upstream 100 bases:

>100_bases
CGGATCTCTTAGGCGGATATCTTATAAGAGCGCATCACAAGGAATACGACAGAAGTTTTGAAGGACGTTTTTGTCAGCTT
GAAAGAAAATTAACTGGGAG

Downstream 100 bases:

>100_bases
TGCATGTGTGCTAAAAGAAAGGTAAGCGTATAGATATGGCAAACACAAAGGAAATTCAGGATCGAATAAAAAGTATCAAT
GATACATTAAAGATTACTAA

Product: ATP synthase

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 501; Mature: 500

Protein sequence:

>501_residues
MTPVGAISATDIISIIQSEIENFNWDEASRETGNVIWVGDGIATVYGIDHAMYGEIVVFDNGVKGMVQDIRENEIGVILF
GRDTGIKEGTKVVRTKKKAGIPVGSAFVGRVINALGEPIDGKGDIKEEDYRPIEEDAPGIVDRKSVSTPMETGILSIDSM
FPIGRGQRELIIGDRQTGKTSIATDTIINQKGKGVICVYVAIGQKASTVAKVVSTLTKHGAMDYSIVVSSTASDPASLQY
IAPYAGTAMAEHFMHQGKDVLIVYDDLSKHAVAYRALSLLLERSPGREAYPGDVFYLHSRLLERSSRLSDALGGGSITAL
PIIETQAGDVSAYIPTNVISITDGQIFLETNLFNSGMRPAVNVGLSVSRVGGAAQTKAMKKASGSIRIDLAQYREMEVFT
QFASDLDDATKAQLQHGKALMELLKQPLCHPLSMHEQVMTLVMANNGVFDEIPTKEVKKHQTELLEFIDLKHPEIGKQIE
DEKEINDELVKNILEAVKEFA

Sequences:

>Translated_501_residues
MTPVGAISATDIISIIQSEIENFNWDEASRETGNVIWVGDGIATVYGIDHAMYGEIVVFDNGVKGMVQDIRENEIGVILF
GRDTGIKEGTKVVRTKKKAGIPVGSAFVGRVINALGEPIDGKGDIKEEDYRPIEEDAPGIVDRKSVSTPMETGILSIDSM
FPIGRGQRELIIGDRQTGKTSIATDTIINQKGKGVICVYVAIGQKASTVAKVVSTLTKHGAMDYSIVVSSTASDPASLQY
IAPYAGTAMAEHFMHQGKDVLIVYDDLSKHAVAYRALSLLLERSPGREAYPGDVFYLHSRLLERSSRLSDALGGGSITAL
PIIETQAGDVSAYIPTNVISITDGQIFLETNLFNSGMRPAVNVGLSVSRVGGAAQTKAMKKASGSIRIDLAQYREMEVFT
QFASDLDDATKAQLQHGKALMELLKQPLCHPLSMHEQVMTLVMANNGVFDEIPTKEVKKHQTELLEFIDLKHPEIGKQIE
DEKEINDELVKNILEAVKEFA
>Mature_500_residues
TPVGAISATDIISIIQSEIENFNWDEASRETGNVIWVGDGIATVYGIDHAMYGEIVVFDNGVKGMVQDIRENEIGVILFG
RDTGIKEGTKVVRTKKKAGIPVGSAFVGRVINALGEPIDGKGDIKEEDYRPIEEDAPGIVDRKSVSTPMETGILSIDSMF
PIGRGQRELIIGDRQTGKTSIATDTIINQKGKGVICVYVAIGQKASTVAKVVSTLTKHGAMDYSIVVSSTASDPASLQYI
APYAGTAMAEHFMHQGKDVLIVYDDLSKHAVAYRALSLLLERSPGREAYPGDVFYLHSRLLERSSRLSDALGGGSITALP
IIETQAGDVSAYIPTNVISITDGQIFLETNLFNSGMRPAVNVGLSVSRVGGAAQTKAMKKASGSIRIDLAQYREMEVFTQ
FASDLDDATKAQLQHGKALMELLKQPLCHPLSMHEQVMTLVMANNGVFDEIPTKEVKKHQTELLEFIDLKHPEIGKQIED
EKEINDELVKNILEAVKEFA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=498, Percent_Identity=54.0160642570281, Blast_Score=527, Evalue=1e-150,
Organism=Homo sapiens, GI4757810, Length=498, Percent_Identity=54.0160642570281, Blast_Score=527, Evalue=1e-150,
Organism=Homo sapiens, GI19913428, Length=356, Percent_Identity=28.9325842696629, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI19913426, Length=352, Percent_Identity=29.2613636363636, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI32189394, Length=313, Percent_Identity=26.1980830670927, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI19913424, Length=257, Percent_Identity=25.2918287937743, Blast_Score=70, Evalue=6e-12,
Organism=Escherichia coli, GI1790172, Length=506, Percent_Identity=50.9881422924901, Blast_Score=524, Evalue=1e-150,
Organism=Escherichia coli, GI1790170, Length=317, Percent_Identity=27.1293375394322, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1788251, Length=328, Percent_Identity=25.609756097561, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71988080, Length=501, Percent_Identity=54.0918163672655, Blast_Score=536, Evalue=1e-153,
Organism=Caenorhabditis elegans, GI71988063, Length=501, Percent_Identity=54.0918163672655, Blast_Score=536, Evalue=1e-153,
Organism=Caenorhabditis elegans, GI71988074, Length=501, Percent_Identity=50.8982035928144, Blast_Score=491, Evalue=1e-139,
Organism=Caenorhabditis elegans, GI17510931, Length=367, Percent_Identity=28.6103542234332, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17570191, Length=368, Percent_Identity=27.9891304347826, Blast_Score=114, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI25144756, Length=433, Percent_Identity=23.7875288683603, Blast_Score=92, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=62, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17565854, Length=255, Percent_Identity=25.0980392156863, Blast_Score=68, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=499, Percent_Identity=52.5050100200401, Blast_Score=526, Evalue=1e-150,
Organism=Saccharomyces cerevisiae, GI6319603, Length=348, Percent_Identity=29.8850574712644, Blast_Score=122, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6322581, Length=374, Percent_Identity=24.5989304812834, Blast_Score=107, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24658560, Length=468, Percent_Identity=56.6239316239316, Blast_Score=529, Evalue=1e-150,
Organism=Drosophila melanogaster, GI281361666, Length=298, Percent_Identity=29.1946308724832, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24646341, Length=298, Percent_Identity=29.1946308724832, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI17136796, Length=298, Percent_Identity=29.1946308724832, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24638766, Length=313, Percent_Identity=26.8370607028754, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28574560, Length=390, Percent_Identity=23.5897435897436, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24583988, Length=257, Percent_Identity=25.2918287937743, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24583986, Length=257, Percent_Identity=25.2918287937743, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24583984, Length=257, Percent_Identity=25.2918287937743, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24583992, Length=256, Percent_Identity=24.609375, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI20129479, Length=256, Percent_Identity=25.78125, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 54409; Mature: 54278

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPVGAISATDIISIIQSEIENFNWDEASRETGNVIWVGDGIATVYGIDHAMYGEIVVFD
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCEEEEHCCCHHHHCCEEEEE
NGVKGMVQDIRENEIGVILFGRDTGIKEGTKVVRTKKKAGIPVGSAFVGRVINALGEPID
CCHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCC
GKGDIKEEDYRPIEEDAPGIVDRKSVSTPMETGILSIDSMFPIGRGQRELIIGDRQTGKT
CCCCCCCCCCCCCHHCCCCCCCCCCCCCCHHHCCEEECCCCCCCCCCCEEEEECCCCCCC
SIATDTIINQKGKGVICVYVAIGQKASTVAKVVSTLTKHGAMDYSIVVSSTASDPASLQY
CHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEE
IAPYAGTAMAEHFMHQGKDVLIVYDDLSKHAVAYRALSLLLERSPGREAYPGDVFYLHSR
ECCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
LLERSSRLSDALGGGSITALPIIETQAGDVSAYIPTNVISITDGQIFLETNLFNSGMRPA
HHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEECCCCCCCCCH
VNVGLSVSRVGGAAQTKAMKKASGSIRIDLAQYREMEVFTQFASDLDDATKAQLQHGKAL
HHCCEEHHHCCCHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MELLKQPLCHPLSMHEQVMTLVMANNGVFDEIPTKEVKKHQTELLEFIDLKHPEIGKQIE
HHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
DEKEINDELVKNILEAVKEFA
HHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TPVGAISATDIISIIQSEIENFNWDEASRETGNVIWVGDGIATVYGIDHAMYGEIVVFD
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCEEEEHCCCHHHHCCEEEEE
NGVKGMVQDIRENEIGVILFGRDTGIKEGTKVVRTKKKAGIPVGSAFVGRVINALGEPID
CCHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCC
GKGDIKEEDYRPIEEDAPGIVDRKSVSTPMETGILSIDSMFPIGRGQRELIIGDRQTGKT
CCCCCCCCCCCCCHHCCCCCCCCCCCCCCHHHCCEEECCCCCCCCCCCEEEEECCCCCCC
SIATDTIINQKGKGVICVYVAIGQKASTVAKVVSTLTKHGAMDYSIVVSSTASDPASLQY
CHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEE
IAPYAGTAMAEHFMHQGKDVLIVYDDLSKHAVAYRALSLLLERSPGREAYPGDVFYLHSR
ECCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
LLERSSRLSDALGGGSITALPIIETQAGDVSAYIPTNVISITDGQIFLETNLFNSGMRPA
HHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEECCCCCCCCCH
VNVGLSVSRVGGAAQTKAMKKASGSIRIDLAQYREMEVFTQFASDLDDATKAQLQHGKAL
HHCCEEHHHCCCHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MELLKQPLCHPLSMHEQVMTLVMANNGVFDEIPTKEVKKHQTELLEFIDLKHPEIGKQIE
HHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
DEKEINDELVKNILEAVKEFA
HHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA