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The map label for this gene is yjmB [H]

Identifier: 238917239

GI number: 238917239

Start: 1349231

End: 1350658

Strand: Reverse

Name: yjmB [H]

Synonym: EUBELI_01312

Alternate gene names: 238917239

Gene position: 1350658-1349231 (Counterclockwise)

Preceding gene: 238917240

Following gene: 238917238

Centisome position: 62.99

GC content: 35.64

Gene sequence:

>1428_bases
ATGGAGAATAAGCATGGGCATATAGAGCAGAACAGAGCCAGAATATGGCAGATTGGCTTGTTTTCTCTTAATAATACATC
TACAAATCTGTTTCTTGCGATGATGGGATATGTCTCATATTATGCTAATGGAATAGCAGGTCTTTCAGTTGTGCTTATTT
CAGTTATTCTTACGGGAATGAGAATATTTGATGGGGTAACAGATCCGGTAATAGGGTATTTTATAGATAAGACTAATGGA
AAATATGGTAAATTCAGGCCTTATATTGTTATAGGATACTTACTAATGGCAATTAGCAGTCTTGTACTGTTCTTTACTAC
AAGCCTTGTTCCAGTTATTTTAAGACCATTGTATTTTATAATTGTATATTCAGTATATATAATAGGATACACATTTCAGA
CAGCAGTTGTAAAGTCTGGACAATCGGTAATTACTAATGACATGAAGCAGAGGCCAATGATAACATTTTTTGACTCAACA
TTTATAATGTTCGCACATGGTCTGGTTGCTTTTTATGTGTCGGTGTATCTGATTGAGAAATACAAGACATTCCAGTCACA
GGCACTTTTCTCAGAGTTCGTAATCACAGTGGTTATTGTAGCCGGAATATGCTCAGCACTGGCTGTTGTGGGAATATGGA
GTAAGGATAATGTAAAGTACTTCAAGCTTGATGAGGATAAGAAGCAGCAGATACATTTCAGGGATTATGCGGCTATAATT
AAACACAACAAGCCAATCAGAATGCTTGTTATTGCGGCGGCATCTAACAAATTCGCACAGATGGTATATGGTAATTCAAC
AGTTCTTGTAATGCTTTATGGAATACTGATGCAGAATTATCCGCTGGCTGGTATAATTGGAATAATTGTAGGTATTCCTA
ATCTGGGAATAATATATATTGGGATAGAGCATGCCAAGCGATGCGGACAGAAGAAGACACTTGTAAGGTCAACATATCTT
GCAATTATTTTTCAGACGATACTTATGTTTATGATGATATTTTCAGACCTTACAAATGTATCATTAAGACATATTAACTT
TATATCGGTAGCGTTTTTGTTAGTGTTTACACTGCTTAACGGAGTAAAATCAATATCTAATAATATAGTTGTTCCTATGA
TTGCCGATTGTACTGATTACGAATATACACTGAGCGGACATTTTGTGCCGGGAATAATGGGAGCACTGTTTTCATTTATT
GACAAATCATTTTCAGCACTTGGAACAGGATTTGTAGGAATAGCACTTGCGATAGCAGGGTATTCTAAAGTTTTTCCGCA
GGTGGAGGACCAACTGACACCACAGCTTAAGTTTCTGACAATATTTTTCTATTGCATAATTCCGATAATAGGCTGGATTG
TGACAATATTTATAATGAGATTCTATAAGCTGGATAAGAATACTATGAGGGGCTTGTATAAAAAATAG

Upstream 100 bases:

>100_bases
ATGTTGCTGAGGAAAGCTTCATACCTGAATTTGACTATGAGGGCATATGATTATATAATCGTAACAGAGATTATTACAAA
TGTATTGGCAGGATTAATAT

Downstream 100 bases:

>100_bases
AGTGGAGATTAATATGCTTATTAGTAAAGGAAATCCCATGCTTATGGGATGCAGCAGATATAAGGACGGATATAATTTTA
CATATGAGGCAGAATGTGAC

Product: glycoside/pentoside/hexuronide:cation symporter

Products: Li (I) [Cytoplasm]; melibiose [Cytoplasm]; Na (I) [Cytoplasm]; melibiose [Cytoplasm]; Proton [Cytoplasm]; melibiose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 475

Protein sequence:

>475_residues
MENKHGHIEQNRARIWQIGLFSLNNTSTNLFLAMMGYVSYYANGIAGLSVVLISVILTGMRIFDGVTDPVIGYFIDKTNG
KYGKFRPYIVIGYLLMAISSLVLFFTTSLVPVILRPLYFIIVYSVYIIGYTFQTAVVKSGQSVITNDMKQRPMITFFDST
FIMFAHGLVAFYVSVYLIEKYKTFQSQALFSEFVITVVIVAGICSALAVVGIWSKDNVKYFKLDEDKKQQIHFRDYAAII
KHNKPIRMLVIAAASNKFAQMVYGNSTVLVMLYGILMQNYPLAGIIGIIVGIPNLGIIYIGIEHAKRCGQKKTLVRSTYL
AIIFQTILMFMMIFSDLTNVSLRHINFISVAFLLVFTLLNGVKSISNNIVVPMIADCTDYEYTLSGHFVPGIMGALFSFI
DKSFSALGTGFVGIALAIAGYSKVFPQVEDQLTPQLKFLTIFFYCIIPIIGWIVTIFIMRFYKLDKNTMRGLYKK

Sequences:

>Translated_475_residues
MENKHGHIEQNRARIWQIGLFSLNNTSTNLFLAMMGYVSYYANGIAGLSVVLISVILTGMRIFDGVTDPVIGYFIDKTNG
KYGKFRPYIVIGYLLMAISSLVLFFTTSLVPVILRPLYFIIVYSVYIIGYTFQTAVVKSGQSVITNDMKQRPMITFFDST
FIMFAHGLVAFYVSVYLIEKYKTFQSQALFSEFVITVVIVAGICSALAVVGIWSKDNVKYFKLDEDKKQQIHFRDYAAII
KHNKPIRMLVIAAASNKFAQMVYGNSTVLVMLYGILMQNYPLAGIIGIIVGIPNLGIIYIGIEHAKRCGQKKTLVRSTYL
AIIFQTILMFMMIFSDLTNVSLRHINFISVAFLLVFTLLNGVKSISNNIVVPMIADCTDYEYTLSGHFVPGIMGALFSFI
DKSFSALGTGFVGIALAIAGYSKVFPQVEDQLTPQLKFLTIFFYCIIPIIGWIVTIFIMRFYKLDKNTMRGLYKK
>Mature_475_residues
MENKHGHIEQNRARIWQIGLFSLNNTSTNLFLAMMGYVSYYANGIAGLSVVLISVILTGMRIFDGVTDPVIGYFIDKTNG
KYGKFRPYIVIGYLLMAISSLVLFFTTSLVPVILRPLYFIIVYSVYIIGYTFQTAVVKSGQSVITNDMKQRPMITFFDST
FIMFAHGLVAFYVSVYLIEKYKTFQSQALFSEFVITVVIVAGICSALAVVGIWSKDNVKYFKLDEDKKQQIHFRDYAAII
KHNKPIRMLVIAAASNKFAQMVYGNSTVLVMLYGILMQNYPLAGIIGIIVGIPNLGIIYIGIEHAKRCGQKKTLVRSTYL
AIIFQTILMFMMIFSDLTNVSLRHINFISVAFLLVFTLLNGVKSISNNIVVPMIADCTDYEYTLSGHFVPGIMGALFSFI
DKSFSALGTGFVGIALAIAGYSKVFPQVEDQLTPQLKFLTIFFYCIIPIIGWIVTIFIMRFYKLDKNTMRGLYKK

Specific function: Responsible For Melibiose Transport. It Is Capable Of Using Hydrogen, Sodium, And Lithium Cations As Coupling Cations For Cotransport, Depending On The Particular Sugar Transported (Symport System). [C]

COG id: COG2211

COG function: function code G; Na+/melibiose symporter and related transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:galactoside symporter (TC 2.A.2) family [H]

Homologues:

Organism=Escherichia coli, GI1790561, Length=441, Percent_Identity=24.0362811791383, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786466, Length=132, Percent_Identity=27.2727272727273, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001927
- InterPro:   IPR018043 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 53481; Mature: 53481

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENKHGHIEQNRARIWQIGLFSLNNTSTNLFLAMMGYVSYYANGIAGLSVVLISVILTGM
CCCCCCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIFDGVTDPVIGYFIDKTNGKYGKFRPYIVIGYLLMAISSLVLFFTTSLVPVILRPLYFI
HHHCCCCCHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVYSVYIIGYTFQTAVVKSGQSVITNDMKQRPMITFFDSTFIMFAHGLVAFYVSVYLIEK
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
YKTFQSQALFSEFVITVVIVAGICSALAVVGIWSKDNVKYFKLDEDKKQQIHFRDYAAII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEECCCHHHHHHHHHHHHHH
KHNKPIRMLVIAAASNKFAQMVYGNSTVLVMLYGILMQNYPLAGIIGIIVGIPNLGIIYI
HCCCCEEEEEEEECCCCHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEE
GIEHAKRCGQKKTLVRSTYLAIIFQTILMFMMIFSDLTNVSLRHINFISVAFLLVFTLLN
EHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
GVKSISNNIVVPMIADCTDYEYTLSGHFVPGIMGALFSFIDKSFSALGTGFVGIALAIAG
HHHHHHCCEEEEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
YSKVFPQVEDQLTPQLKFLTIFFYCIIPIIGWIVTIFIMRFYKLDKNTMRGLYKK
HHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCC
>Mature Secondary Structure
MENKHGHIEQNRARIWQIGLFSLNNTSTNLFLAMMGYVSYYANGIAGLSVVLISVILTGM
CCCCCCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIFDGVTDPVIGYFIDKTNGKYGKFRPYIVIGYLLMAISSLVLFFTTSLVPVILRPLYFI
HHHCCCCCHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVYSVYIIGYTFQTAVVKSGQSVITNDMKQRPMITFFDSTFIMFAHGLVAFYVSVYLIEK
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
YKTFQSQALFSEFVITVVIVAGICSALAVVGIWSKDNVKYFKLDEDKKQQIHFRDYAAII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEECCCHHHHHHHHHHHHHH
KHNKPIRMLVIAAASNKFAQMVYGNSTVLVMLYGILMQNYPLAGIIGIIVGIPNLGIIYI
HCCCCEEEEEEEECCCCHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEE
GIEHAKRCGQKKTLVRSTYLAIIFQTILMFMMIFSDLTNVSLRHINFISVAFLLVFTLLN
EHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
GVKSISNNIVVPMIADCTDYEYTLSGHFVPGIMGALFSFIDKSFSALGTGFVGIALAIAG
HHHHHHCCEEEEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
YSKVFPQVEDQLTPQLKFLTIFFYCIIPIIGWIVTIFIMRFYKLDKNTMRGLYKK
HHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Li (I) [Periplasm]; melibiose [Periplasm]; Na (I) [Periplasm]; melibiose [Periplasm]; Proton [Periplasm]; melibiose [Periplasm] [C]

Specific reaction: Li (I) [Periplasm] + melibiose [Periplasm] = Li (I) [Cytoplasm] + melibiose [Cytoplasm] Na (I) [Periplasm] + melibiose [Periplasm] = Na (I) [Cytoplasm] + melibiose [Cytoplasm] Proton [Periplasm] + melibiose [Periplasm] = Proton [Cytoplasm] + melibiose [Cy

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]