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The map label for this gene is yoeA [H]

Identifier: 238917223

GI number: 238917223

Start: 1335365

End: 1336705

Strand: Reverse

Name: yoeA [H]

Synonym: EUBELI_01296

Alternate gene names: 238917223

Gene position: 1336705-1335365 (Counterclockwise)

Preceding gene: 238917224

Following gene: 238917222

Centisome position: 62.34

GC content: 38.18

Gene sequence:

>1341_bases
ATGAAAGATTTAACTAAGGGAAGTATAACTAAGCTTATATTCTGGTTTGCATTACCGGTTTTTATAGGCTCGTTGCTTCA
GATGACTTATAATCTTGTGGATACCAAGATTATAGGGTATGTATTAGGAGAAAGTTCACTGGCGGCTGTAGGGTCTACTA
ACTCAGTGAACACCCTTGTTATAGGCTTTTTACAGGGACTGACTAATGGATTTGCTGTTATTGCTGCACAGTTTTTTGGG
GCAGGAGATACAGCTAATTTTAAGAGGACAGTTGCAGGTTCGTTCAAATATGGAATTATGATATCAGCAGGTCTGACAGT
GGTTGTGCTGATATTTTTACGACCTCTTCTGAAAGTACTTAATACACCAGAGGATTTGTTAAAGGAAGCCTATGATTATA
TATTTATAATATTTGCAGGCATGACAATACTTATGCTTTACAATGTCTGTGCAGCCCTGTTAAGGTCGATAGGAGATTCA
TTTACTCCGCTTATTTTTTTAGGAATATCAGTAGTGCTTAACATTGGTGGAGACTTATTTTTCCTTAAGGTTATTCCAAT
GGGGGTAAGAGGTGCTGCAGTGGCAACAGTGCTTTCACAGCTCATAGCACTTATCGCGTGTCTTATATATTCACTTAAAA
GATACAACATACTGTGGATTGAAAAGAAAGATTTTAAGAGTGATGCCAGTCTGTGTGGAAAACTTATGTCAACAGGCTGT
TCCATGGGCTTTATGAGCAGTCTTGTATCAATTGGCTCTGTTACATTGCAGAGTGCAATCAATTCATTTGGACAGGATAT
AATTCTTGCCCATACTACTGCAAGAAGATTATCAGAGCTTTTCATGATGATGTTCGGTGTGCTGGGAACTACGATGGCAA
CCTTTTGTGGACAGAATCTTGGAGCAGGAAAGTATGAAAGAATAAGAAAGGGCATATTAACATCTATTCTTATGGGATGG
GTATGGTGTGTGTTATGTGTAATCACATCTTATACGATAGTTCCTGCATTTGTTAAAATGCTTATAAGTTCGGATAACAA
AAATGTAATAGATACAGCAACGCTGTATTTAAGAGTTGACTCGTTGCTTTATTTTGTGACAGCGATGATAACTATCATAA
GAAATTCACTGCAGGGAATAGGTGACAGGCTTACGCCTATCATATCAAGCGGGATTGAGCTTGCAGGAAAGGTTGTTATA
ACATTTACACTTGTTCCATTAATGGGATACTGGGGTGTTATAGTTTCAGAGCCTATAGTATGGGTTCTGATGGTTATTCC
GCTTATTGTGCAGTTAATAAAGAATCCGGCATTTGCCAGAGGAAAGAATAACGGAGGATGA

Upstream 100 bases:

>100_bases
CTGTTTATAACCAGACTTTTGATGAAGTTGCTGAAGAGATGGATGCATTTTTATCAGTGGATTAATTGGGCAGAATTAAG
AACTATATAGGAATATTTGT

Downstream 100 bases:

>100_bases
TTTATGGCAGAGAATACCAAGAATGTTGAATTTAAGAATCCACATCCTGAGCTTCCTGTAAGGGAACCAATCCTTAAACT
TGGAAAGATGGTTACTGACA

Product: MATE family multidrug resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MKDLTKGSITKLIFWFALPVFIGSLLQMTYNLVDTKIIGYVLGESSLAAVGSTNSVNTLVIGFLQGLTNGFAVIAAQFFG
AGDTANFKRTVAGSFKYGIMISAGLTVVVLIFLRPLLKVLNTPEDLLKEAYDYIFIIFAGMTILMLYNVCAALLRSIGDS
FTPLIFLGISVVLNIGGDLFFLKVIPMGVRGAAVATVLSQLIALIACLIYSLKRYNILWIEKKDFKSDASLCGKLMSTGC
SMGFMSSLVSIGSVTLQSAINSFGQDIILAHTTARRLSELFMMMFGVLGTTMATFCGQNLGAGKYERIRKGILTSILMGW
VWCVLCVITSYTIVPAFVKMLISSDNKNVIDTATLYLRVDSLLYFVTAMITIIRNSLQGIGDRLTPIISSGIELAGKVVI
TFTLVPLMGYWGVIVSEPIVWVLMVIPLIVQLIKNPAFARGKNNGG

Sequences:

>Translated_446_residues
MKDLTKGSITKLIFWFALPVFIGSLLQMTYNLVDTKIIGYVLGESSLAAVGSTNSVNTLVIGFLQGLTNGFAVIAAQFFG
AGDTANFKRTVAGSFKYGIMISAGLTVVVLIFLRPLLKVLNTPEDLLKEAYDYIFIIFAGMTILMLYNVCAALLRSIGDS
FTPLIFLGISVVLNIGGDLFFLKVIPMGVRGAAVATVLSQLIALIACLIYSLKRYNILWIEKKDFKSDASLCGKLMSTGC
SMGFMSSLVSIGSVTLQSAINSFGQDIILAHTTARRLSELFMMMFGVLGTTMATFCGQNLGAGKYERIRKGILTSILMGW
VWCVLCVITSYTIVPAFVKMLISSDNKNVIDTATLYLRVDSLLYFVTAMITIIRNSLQGIGDRLTPIISSGIELAGKVVI
TFTLVPLMGYWGVIVSEPIVWVLMVIPLIVQLIKNPAFARGKNNGG
>Mature_446_residues
MKDLTKGSITKLIFWFALPVFIGSLLQMTYNLVDTKIIGYVLGESSLAAVGSTNSVNTLVIGFLQGLTNGFAVIAAQFFG
AGDTANFKRTVAGSFKYGIMISAGLTVVVLIFLRPLLKVLNTPEDLLKEAYDYIFIIFAGMTILMLYNVCAALLRSIGDS
FTPLIFLGISVVLNIGGDLFFLKVIPMGVRGAAVATVLSQLIALIACLIYSLKRYNILWIEKKDFKSDASLCGKLMSTGC
SMGFMSSLVSIGSVTLQSAINSFGQDIILAHTTARRLSELFMMMFGVLGTTMATFCGQNLGAGKYERIRKGILTSILMGW
VWCVLCVITSYTIVPAFVKMLISSDNKNVIDTATLYLRVDSLLYFVTAMITIIRNSLQGIGDRLTPIISSGIELAGKVVI
TFTLVPLMGYWGVIVSEPIVWVLMVIPLIVQLIKNPAFARGKNNGG

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 48357; Mature: 48357

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDLTKGSITKLIFWFALPVFIGSLLQMTYNLVDTKIIGYVLGESSLAAVGSTNSVNTLV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEECCCCCCHHHHH
IGFLQGLTNGFAVIAAQFFGAGDTANFKRTVAGSFKYGIMISAGLTVVVLIFLRPLLKVL
HHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHH
NTPEDLLKEAYDYIFIIFAGMTILMLYNVCAALLRSIGDSFTPLIFLGISVVLNIGGDLF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEE
FLKVIPMGVRGAAVATVLSQLIALIACLIYSLKRYNILWIEKKDFKSDASLCGKLMSTGC
EHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHCCC
SMGFMSSLVSIGSVTLQSAINSFGQDIILAHTTARRLSELFMMMFGVLGTTMATFCGQNL
CHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GAGKYERIRKGILTSILMGWVWCVLCVITSYTIVPAFVKMLISSDNKNVIDTATLYLRVD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
SLLYFVTAMITIIRNSLQGIGDRLTPIISSGIELAGKVVITFTLVPLMGYWGVIVSEPIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WVLMVIPLIVQLIKNPAFARGKNNGG
HHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MKDLTKGSITKLIFWFALPVFIGSLLQMTYNLVDTKIIGYVLGESSLAAVGSTNSVNTLV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEECCCCCCHHHHH
IGFLQGLTNGFAVIAAQFFGAGDTANFKRTVAGSFKYGIMISAGLTVVVLIFLRPLLKVL
HHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHH
NTPEDLLKEAYDYIFIIFAGMTILMLYNVCAALLRSIGDSFTPLIFLGISVVLNIGGDLF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEE
FLKVIPMGVRGAAVATVLSQLIALIACLIYSLKRYNILWIEKKDFKSDASLCGKLMSTGC
EHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHCCC
SMGFMSSLVSIGSVTLQSAINSFGQDIILAHTTARRLSELFMMMFGVLGTTMATFCGQNL
CHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GAGKYERIRKGILTSILMGWVWCVLCVITSYTIVPAFVKMLISSDNKNVIDTATLYLRVD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
SLLYFVTAMITIIRNSLQGIGDRLTPIISSGIELAGKVVITFTLVPLMGYWGVIVSEPIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WVLMVIPLIVQLIKNPAFARGKNNGG
HHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]