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The map label for this gene is asd [H]

Identifier: 238917175

GI number: 238917175

Start: 1268622

End: 1269719

Strand: Reverse

Name: asd [H]

Synonym: EUBELI_01248

Alternate gene names: 238917175

Gene position: 1269719-1268622 (Counterclockwise)

Preceding gene: 238917176

Following gene: 238917174

Centisome position: 59.22

GC content: 40.62

Gene sequence:

>1098_bases
ATGAGCGATAAGTTAAGAGTTGGTATCCTTGGCGGTACAGGTATGGTAGGACAGAGATTTATAACATTACTTGAGAATCA
TCCTTGGTTTGAGGTCGTTTTAGTAGCAGCTTCAGGACGTTCAGCAGGAAAGCTTTATGAAGATGCTGTTGAAGGACGCT
GGAAGATGCAGACACCAATGCCAGAGTTCGTTAAGAAGATGACTGTATATGATATGGATAAGGATTTTGATGAAATTGTT
TCTAAGGTAGATTTCGTATTCTGTGCAGTTAATATGCCTAAGGACCAGATTAAGGCTATAGAGGAAAGATATGCTAAGGC
AGAAGTTCCAGTTGTTTCTAATAACAGTGCTAATCGTTGGACACCAGATGTTCCTATGGTTGTTCCAGAAATCAACCCAG
AGCATCTTGAAGTTATTAAGTATCAGAGAGAAAGACTTGGTACTAAGAGAGGATTTATCTGTGTTAAGCCTAACTGTTCA
ATCCAGAGCTACACACCTGCTCTTAATGCATTAAAGGAATTCGGACCAAAGCTTGTTGTTGCAACAACATATCAGGCAAT
CTCAGGTGCTGGTAAGACATTTGAGCAGTGGCCAGAGATGGTTGAGAATATCATTCCTTATATTGGTGGAGAAGAAGAAA
AGTCTGAAAAAGAGCCTTTAAGATTATGGGGTAAGATTGAGGACGGAAAGATTGTTCCTGCAAGTGATCCGGTTATCACA
TGCCAGTGTATCAGAGTTCCGGTTCTTGATGGACATACAGCAGCAGTATTTGTTAACTTTGAGAAGAAGCCTACTAAGGA
ACAGATTATTGAAAAGTGGAGAAGCTTCAAGGGAGTTCCACAGGAACTTAATCTTCCAAGTGCTCCAAAGCAGTTCATCC
AGTATCTTGAAGAGGATGACCGTCCACAGGTTAAGCTTGATGTTAATTATGAGAATGGAATGGGTGTTTCACTTGGCCGT
TTAAGAGAAGACAGTGTGTTTGATTATAAGTTTGTTGGTCTTTCACACAACACATTAAGAGGTGCAGCAGGTGGAGCTGT
TCTTATTGCAGAGCTTCTTAAGGCACAGGGTTATATCACTCCTAAGGATGCAGAATAA

Upstream 100 bases:

>100_bases
GCTGTGATATATTTTCTTAGACACAAAAACAAATGTCCGTCACAGAAAGACAGAACAGAGGGAAGTGTCTTTTAGATTTT
ACATATTGAAGGAGTTAAAA

Downstream 100 bases:

>100_bases
TTAAATTCTAATACACATACCAGAAAAGAGATGTCAGAGATGGCATCTCTTTTTACTTGCTTAAAAACCTATTATGATAT
AAAATTATGAAACGACTTAA

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MSDKLRVGILGGTGMVGQRFITLLENHPWFEVVLVAASGRSAGKLYEDAVEGRWKMQTPMPEFVKKMTVYDMDKDFDEIV
SKVDFVFCAVNMPKDQIKAIEERYAKAEVPVVSNNSANRWTPDVPMVVPEINPEHLEVIKYQRERLGTKRGFICVKPNCS
IQSYTPALNALKEFGPKLVVATTYQAISGAGKTFEQWPEMVENIIPYIGGEEEKSEKEPLRLWGKIEDGKIVPASDPVIT
CQCIRVPVLDGHTAAVFVNFEKKPTKEQIIEKWRSFKGVPQELNLPSAPKQFIQYLEEDDRPQVKLDVNYENGMGVSLGR
LREDSVFDYKFVGLSHNTLRGAAGGAVLIAELLKAQGYITPKDAE

Sequences:

>Translated_365_residues
MSDKLRVGILGGTGMVGQRFITLLENHPWFEVVLVAASGRSAGKLYEDAVEGRWKMQTPMPEFVKKMTVYDMDKDFDEIV
SKVDFVFCAVNMPKDQIKAIEERYAKAEVPVVSNNSANRWTPDVPMVVPEINPEHLEVIKYQRERLGTKRGFICVKPNCS
IQSYTPALNALKEFGPKLVVATTYQAISGAGKTFEQWPEMVENIIPYIGGEEEKSEKEPLRLWGKIEDGKIVPASDPVIT
CQCIRVPVLDGHTAAVFVNFEKKPTKEQIIEKWRSFKGVPQELNLPSAPKQFIQYLEEDDRPQVKLDVNYENGMGVSLGR
LREDSVFDYKFVGLSHNTLRGAAGGAVLIAELLKAQGYITPKDAE
>Mature_364_residues
SDKLRVGILGGTGMVGQRFITLLENHPWFEVVLVAASGRSAGKLYEDAVEGRWKMQTPMPEFVKKMTVYDMDKDFDEIVS
KVDFVFCAVNMPKDQIKAIEERYAKAEVPVVSNNSANRWTPDVPMVVPEINPEHLEVIKYQRERLGTKRGFICVKPNCSI
QSYTPALNALKEFGPKLVVATTYQAISGAGKTFEQWPEMVENIIPYIGGEEEKSEKEPLRLWGKIEDGKIVPASDPVITC
QCIRVPVLDGHTAAVFVNFEKKPTKEQIIEKWRSFKGVPQELNLPSAPKQFIQYLEEDDRPQVKLDVNYENGMGVSLGRL
REDSVFDYKFVGLSHNTLRGAAGGAVLIAELLKAQGYITPKDAE

Specific function: This enzyme catalyzes the second step in the common metabolic pathway to synthesize Thr and Met from Asp [H]

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320362, Length=376, Percent_Identity=41.2234042553192, Blast_Score=248, Evalue=7e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR005676
- InterPro:   IPR012080
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 40957; Mature: 40825

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDKLRVGILGGTGMVGQRFITLLENHPWFEVVLVAASGRSAGKLYEDAVEGRWKMQTPM
CCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHCCCEEECCCH
PEFVKKMTVYDMDKDFDEIVSKVDFVFCAVNMPKDQIKAIEERYAKAEVPVVSNNSANRW
HHHHHHHHHHCCCCCHHHHHHHHCEEEEEECCCHHHHHHHHHHHHHCCCCEEECCCCCCC
TPDVPMVVPEINPEHLEVIKYQRERLGTKRGFICVKPNCSIQSYTPALNALKEFGPKLVV
CCCCCEEECCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHCCCEEEE
ATTYQAISGAGKTFEQWPEMVENIIPYIGGEEEKSEKEPLRLWGKIEDGKIVPASDPVIT
EEEHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHEEECCCCEEECCCCCEEE
CQCIRVPVLDGHTAAVFVNFEKKPTKEQIIEKWRSFKGVPQELNLPSAPKQFIQYLEEDD
EEEEEEEEECCCEEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCC
RPQVKLDVNYENGMGVSLGRLREDSVFDYKFVGLSHNTLRGAAGGAVLIAELLKAQGYIT
CCEEEEEEECCCCCCCCHHCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCC
PKDAE
CCCCC
>Mature Secondary Structure 
SDKLRVGILGGTGMVGQRFITLLENHPWFEVVLVAASGRSAGKLYEDAVEGRWKMQTPM
CCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHCCCEEECCCH
PEFVKKMTVYDMDKDFDEIVSKVDFVFCAVNMPKDQIKAIEERYAKAEVPVVSNNSANRW
HHHHHHHHHHCCCCCHHHHHHHHCEEEEEECCCHHHHHHHHHHHHHCCCCEEECCCCCCC
TPDVPMVVPEINPEHLEVIKYQRERLGTKRGFICVKPNCSIQSYTPALNALKEFGPKLVV
CCCCCEEECCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHCCCEEEE
ATTYQAISGAGKTFEQWPEMVENIIPYIGGEEEKSEKEPLRLWGKIEDGKIVPASDPVIT
EEEHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHEEECCCCEEECCCCCEEE
CQCIRVPVLDGHTAAVFVNFEKKPTKEQIIEKWRSFKGVPQELNLPSAPKQFIQYLEEDD
EEEEEEEEECCCEEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCC
RPQVKLDVNYENGMGVSLGRLREDSVFDYKFVGLSHNTLRGAAGGAVLIAELLKAQGYIT
CCEEEEEEECCCCCCCCHHCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCC
PKDAE
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]