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The map label for this gene is metA

Identifier: 238917129

GI number: 238917129

Start: 1211939

End: 1212871

Strand: Reverse

Name: metA

Synonym: EUBELI_01200

Alternate gene names: 238917129

Gene position: 1212871-1211939 (Counterclockwise)

Preceding gene: 238917130

Following gene: 238917128

Centisome position: 56.57

GC content: 35.58

Gene sequence:

>933_bases
ATGCCAATTAAGATTCAGAGTGATTTACCAGCTAAAGCAGAATTGGAAGAAGAAAATATATTCGTCATGGACGAAAACAG
AGCTATTTCACAGAATATAAGACCTTTGGAGATAATAGTTCTTAATCTTATGCCTATAAAGCAGGATACAGAATTACAGC
TTTTAAGAGGTTTATCTAATACACCTTTACAGATAGATGTTACATTTTTACAGATGTCATCACATGTTTCAAAGAATACC
TCAGCTTCACATATTAAAAAGTTTTATCAGACTTTTGAAGAAATTAAGAATAATAATTATGATGGAATGATTATTACGGG
AGCACCTGTCGAGAAGCTTGACTTTGAAGAGGTTAATTACTGGGATGAACTTATAACAGTAATGGAGTGGTCTAATAAGC
ATGTTACATCAACAATTCATATATGCTGGGGTGCGCAGGCAGGATTGTATTACCATTATGGTATTAAGAAGGAATTACTT
CCGAAGAAGCTGTCAGGTGTGTACAAGCACAGGGTTATGAATAGAAAAGAGCCTTTAGTAAGAGGCTTTGATGATGTATT
CATGGCACCACATTCAAGATATACACAGGCAAGCAGACAGCAGATTCTTGACAATCCAAGACTTAAAGTACTTGCAGATT
CAGATGAGGCAGGAATATATATTGTTCTTGGTGATGGCGGGAAAGAGATTTTTGTTATGGGACACCCTGAATATGACAGA
TTAACTCTTGATCAGGAATATAAGCGTGATATTGACAAAGGAATTGAGCCTGACCTTCCGGTAAATTATTATCCTGATGA
CGACTGCAACAGAAAACCATTGCTCTCATGGAGAAGCCACGCCAACAATCTCTATACTAACTGGTTGAATTATTATGTAT
ACCAGATAACTCCTTATGACCTTAATGAAAGTTATGATAATTACTGTATTTAA

Upstream 100 bases:

>100_bases
TGAATTTATGGAAATGATAAAGTAAAGAAAATTTTTATGCAGTTATTAAAGATGATATGATATAATCAGACAGCAATGAT
AACAGAAAGAAGGAACAGTA

Downstream 100 bases:

>100_bases
GAGGGGTGTAGATACTTTTGTTTTGTTGAACTATTGAAATAAATATATGAAAGATTGAAACAGATAGGTGTTGACAAAAC
ATAAAATAATGTATATATTT

Product: homoserine O-succinyltransferase

Products: NA

Alternate protein names: Homoserine O-transsuccinylase; HTS

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MPIKIQSDLPAKAELEEENIFVMDENRAISQNIRPLEIIVLNLMPIKQDTELQLLRGLSNTPLQIDVTFLQMSSHVSKNT
SASHIKKFYQTFEEIKNNNYDGMIITGAPVEKLDFEEVNYWDELITVMEWSNKHVTSTIHICWGAQAGLYYHYGIKKELL
PKKLSGVYKHRVMNRKEPLVRGFDDVFMAPHSRYTQASRQQILDNPRLKVLADSDEAGIYIVLGDGGKEIFVMGHPEYDR
LTLDQEYKRDIDKGIEPDLPVNYYPDDDCNRKPLLSWRSHANNLYTNWLNYYVYQITPYDLNESYDNYCI

Sequences:

>Translated_310_residues
MPIKIQSDLPAKAELEEENIFVMDENRAISQNIRPLEIIVLNLMPIKQDTELQLLRGLSNTPLQIDVTFLQMSSHVSKNT
SASHIKKFYQTFEEIKNNNYDGMIITGAPVEKLDFEEVNYWDELITVMEWSNKHVTSTIHICWGAQAGLYYHYGIKKELL
PKKLSGVYKHRVMNRKEPLVRGFDDVFMAPHSRYTQASRQQILDNPRLKVLADSDEAGIYIVLGDGGKEIFVMGHPEYDR
LTLDQEYKRDIDKGIEPDLPVNYYPDDDCNRKPLLSWRSHANNLYTNWLNYYVYQITPYDLNESYDNYCI
>Mature_309_residues
PIKIQSDLPAKAELEEENIFVMDENRAISQNIRPLEIIVLNLMPIKQDTELQLLRGLSNTPLQIDVTFLQMSSHVSKNTS
ASHIKKFYQTFEEIKNNNYDGMIITGAPVEKLDFEEVNYWDELITVMEWSNKHVTSTIHICWGAQAGLYYHYGIKKELLP
KKLSGVYKHRVMNRKEPLVRGFDDVFMAPHSRYTQASRQQILDNPRLKVLADSDEAGIYIVLGDGGKEIFVMGHPEYDRL
TLDQEYKRDIDKGIEPDLPVNYYPDDDCNRKPLLSWRSHANNLYTNWLNYYVYQITPYDLNESYDNYCI

Specific function: Methionine biosynthesis; HTS variant; first step. [C]

COG id: COG1897

COG function: function code E; Homoserine trans-succinylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HTS family

Homologues:

Organism=Escherichia coli, GI1790443, Length=301, Percent_Identity=50.8305647840532, Blast_Score=331, Evalue=3e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): META_EUBE2 (C4Z0T6)

Other databases:

- EMBL:   CP001104
- RefSeq:   YP_002930646.1
- ProteinModelPortal:   C4Z0T6
- GeneID:   7957743
- GenomeReviews:   CP001104_GR
- KEGG:   eel:EUBELI_01200
- OMA:   QAGLYYH
- ProtClustDB:   CLSK2506373
- GO:   GO:0005737
- HAMAP:   MF_00295
- InterPro:   IPR005697
- PANTHER:   PTHR20919
- PIRSF:   PIRSF000450
- ProDom:   PD037892
- TIGRFAMs:   TIGR01001

Pfam domain/function: PF04204 HTS

EC number: =2.3.1.46

Molecular weight: Translated: 36167; Mature: 36036

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: ACT_SITE 142-142

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIKIQSDLPAKAELEEENIFVMDENRAISQNIRPLEIIVLNLMPIKQDTELQLLRGLSN
CCEEECCCCCCCCCCCCCCEEEEECCCHHHCCCCEEEEEEEEEECCCCCCHHHHHHCCCC
TPLQIDVTFLQMSSHVSKNTSASHIKKFYQTFEEIKNNNYDGMIITGAPVEKLDFEEVNY
CCEEEEEEEEEHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHH
WDELITVMEWSNKHVTSTIHICWGAQAGLYYHYGIKKELLPKKLSGVYKHRVMNRKEPLV
HHHHHHHHHCCCCEEEEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHH
RGFDDVFMAPHSRYTQASRQQILDNPRLKVLADSDEAGIYIVLGDGGKEIFVMGHPEYDR
HCCHHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEECCCCCEEEEEECCCCCC
LTLDQEYKRDIDKGIEPDLPVNYYPDDDCNRKPLLSWRSHANNLYTNWLNYYVYQITPYD
EECCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHCEEEEEEEEEEECC
LNESYDNYCI
CCCCCCCCCC
>Mature Secondary Structure 
PIKIQSDLPAKAELEEENIFVMDENRAISQNIRPLEIIVLNLMPIKQDTELQLLRGLSN
CEEECCCCCCCCCCCCCCEEEEECCCHHHCCCCEEEEEEEEEECCCCCCHHHHHHCCCC
TPLQIDVTFLQMSSHVSKNTSASHIKKFYQTFEEIKNNNYDGMIITGAPVEKLDFEEVNY
CCEEEEEEEEEHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHH
WDELITVMEWSNKHVTSTIHICWGAQAGLYYHYGIKKELLPKKLSGVYKHRVMNRKEPLV
HHHHHHHHHCCCCEEEEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHH
RGFDDVFMAPHSRYTQASRQQILDNPRLKVLADSDEAGIYIVLGDGGKEIFVMGHPEYDR
HCCHHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEECCCCCEEEEEECCCCCC
LTLDQEYKRDIDKGIEPDLPVNYYPDDDCNRKPLLSWRSHANNLYTNWLNYYVYQITPYD
EECCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHCEEEEEEEEEEECC
LNESYDNYCI
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA