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The map label for this gene is gap [H]

Identifier: 238917119

GI number: 238917119

Start: 1202538

End: 1203566

Strand: Reverse

Name: gap [H]

Synonym: EUBELI_01190

Alternate gene names: 238917119

Gene position: 1203566-1202538 (Counterclockwise)

Preceding gene: 238917120

Following gene: 238917118

Centisome position: 56.13

GC content: 40.62

Gene sequence:

>1029_bases
ATGTCAGTAAAAGTTGCAATCAATGGTTTTGGTCGTATCGGTAGACTTGCATTCAGACAGATGTTTGGTGCAGAAGGATA
TGAGGTAGTTGCTATTAACGATTTAACAAGCCCTAAGATGCTTGCTCATCTTTTAAAGTATGACTCATCACAGGGAAGAT
ATGTTAACTTCGGTGAGGAAGATCAGGTAACAGCTGATGATGAGGCTGGTACAATCACAGTTAAAGGTAAGACTATCAAG
ATTTACAAAGAGCCAGATGCTAATAACTGCCCATGGGGAGAGATTGGTGTTGATGTAGTTCTTGAGTGTTCAGGATTCTA
TACATCTAAGGCTAAGGCACAGGCTCATATTAATGCAGGTGCTAAGAAGGTAGTTATCTCAGCTCCAGCTGGAAATGACC
TTAAGACTATCGTTTACAATGTAAACCATGAGACACTTACAGCAGATGATCAGATTATCTCAGCTGCTTCTTGTACAACA
AACTGTTTAGCTCCTATGGCTAAGGCACTTAACGATTGTGCAACAATCGAGTCAGGTATTATGTGTACAATTCATGCTTA
CACAGGTGACCAGATGATCCTTGACGGACCACAGAGAAAGGGTGATTTAAGAAGATCTAGAGCAGGTGCTTGCAACATCG
TTCCTAACTCAACAGGTGCTGCTAAGGCTATTGGTCTTGTTATCCCAGAACTTAACGGAAAGCTTATTGGAGCTGCTCAG
AGAGTTCCAACACCTACAGGTTCTACAACAATTCTTAATGCTGTAGTTGCTAAGAAGGTTACAGTTGATGAAGTTAATGC
TGCTATGAAGGCTGCTGCAACAGAGTCATTCGGTTACAATACAGAGCAGATTGTATCTAGCGATATCGTTGGTATGAGAT
TTGGTTCATTATTTGATGCTACTCAGACAATGGTTAATGAACTTCCAAACGGTGGTTGCCAGGTTCAGGTTGTTTCTTGG
TATGATAATGAGAACTCATACACAAGCCAGATGGTTAGAACAATTAAGTACTTCGCTGAATTAAACTAA

Upstream 100 bases:

>100_bases
AGAAAGCCTTGATATTTTGCTTCTTCTTATGTAAAATACACGGTAGTTGAAATTTTAACAAACTATGTTATAAAAATTCA
TTTTAGGAGGAATTGTTTTT

Downstream 100 bases:

>100_bases
TCATTTAGATTGTTTTTGCCGGAGAATGGTATGACTATTCTCCGGTTTTTTATAAAGCTGTATATGTAGCTATTTTATGT
ATTATATGGAGGATATTAAT

Product: glyceraldehyde 3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MSVKVAINGFGRIGRLAFRQMFGAEGYEVVAINDLTSPKMLAHLLKYDSSQGRYVNFGEEDQVTADDEAGTITVKGKTIK
IYKEPDANNCPWGEIGVDVVLECSGFYTSKAKAQAHINAGAKKVVISAPAGNDLKTIVYNVNHETLTADDQIISAASCTT
NCLAPMAKALNDCATIESGIMCTIHAYTGDQMILDGPQRKGDLRRSRAGACNIVPNSTGAAKAIGLVIPELNGKLIGAAQ
RVPTPTGSTTILNAVVAKKVTVDEVNAAMKAAATESFGYNTEQIVSSDIVGMRFGSLFDATQTMVNELPNGGCQVQVVSW
YDNENSYTSQMVRTIKYFAELN

Sequences:

>Translated_342_residues
MSVKVAINGFGRIGRLAFRQMFGAEGYEVVAINDLTSPKMLAHLLKYDSSQGRYVNFGEEDQVTADDEAGTITVKGKTIK
IYKEPDANNCPWGEIGVDVVLECSGFYTSKAKAQAHINAGAKKVVISAPAGNDLKTIVYNVNHETLTADDQIISAASCTT
NCLAPMAKALNDCATIESGIMCTIHAYTGDQMILDGPQRKGDLRRSRAGACNIVPNSTGAAKAIGLVIPELNGKLIGAAQ
RVPTPTGSTTILNAVVAKKVTVDEVNAAMKAAATESFGYNTEQIVSSDIVGMRFGSLFDATQTMVNELPNGGCQVQVVSW
YDNENSYTSQMVRTIKYFAELN
>Mature_341_residues
SVKVAINGFGRIGRLAFRQMFGAEGYEVVAINDLTSPKMLAHLLKYDSSQGRYVNFGEEDQVTADDEAGTITVKGKTIKI
YKEPDANNCPWGEIGVDVVLECSGFYTSKAKAQAHINAGAKKVVISAPAGNDLKTIVYNVNHETLTADDQIISAASCTTN
CLAPMAKALNDCATIESGIMCTIHAYTGDQMILDGPQRKGDLRRSRAGACNIVPNSTGAAKAIGLVIPELNGKLIGAAQR
VPTPTGSTTILNAVVAKKVTVDEVNAAMKAAATESFGYNTEQIVSSDIVGMRFGSLFDATQTMVNELPNGGCQVQVVSWY
DNENSYTSQMVRTIKYFAELN

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=344, Percent_Identity=41.2790697674419, Blast_Score=241, Evalue=8e-64,
Organism=Homo sapiens, GI7657116, Length=341, Percent_Identity=39.8826979472141, Blast_Score=228, Evalue=7e-60,
Organism=Escherichia coli, GI1788079, Length=345, Percent_Identity=43.1884057971014, Blast_Score=267, Evalue=6e-73,
Organism=Escherichia coli, GI1789295, Length=344, Percent_Identity=40.1162790697674, Blast_Score=232, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI17534679, Length=344, Percent_Identity=43.6046511627907, Blast_Score=252, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI17534677, Length=344, Percent_Identity=43.3139534883721, Blast_Score=251, Evalue=3e-67,
Organism=Caenorhabditis elegans, GI32566163, Length=344, Percent_Identity=43.8953488372093, Blast_Score=251, Evalue=4e-67,
Organism=Caenorhabditis elegans, GI17568413, Length=344, Percent_Identity=43.8953488372093, Blast_Score=251, Evalue=4e-67,
Organism=Saccharomyces cerevisiae, GI6322409, Length=348, Percent_Identity=43.9655172413793, Blast_Score=273, Evalue=2e-74,
Organism=Saccharomyces cerevisiae, GI6321631, Length=348, Percent_Identity=44.5402298850575, Blast_Score=272, Evalue=4e-74,
Organism=Saccharomyces cerevisiae, GI6322468, Length=348, Percent_Identity=43.6781609195402, Blast_Score=267, Evalue=2e-72,
Organism=Drosophila melanogaster, GI19922412, Length=339, Percent_Identity=43.0678466076696, Blast_Score=259, Evalue=1e-69,
Organism=Drosophila melanogaster, GI17933600, Length=340, Percent_Identity=41.4705882352941, Blast_Score=244, Evalue=7e-65,
Organism=Drosophila melanogaster, GI18110149, Length=340, Percent_Identity=41.4705882352941, Blast_Score=244, Evalue=7e-65,
Organism=Drosophila melanogaster, GI85725000, Length=340, Percent_Identity=41.4705882352941, Blast_Score=243, Evalue=1e-64,
Organism=Drosophila melanogaster, GI22023983, Length=340, Percent_Identity=41.4705882352941, Blast_Score=243, Evalue=1e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36526; Mature: 36395

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVKVAINGFGRIGRLAFRQMFGAEGYEVVAINDLTSPKMLAHLLKYDSSQGRYVNFGEE
CEEEEEECCCCHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCEEECCCC
DQVTADDEAGTITVKGKTIKIYKEPDANNCPWGEIGVDVVLECSGFYTSKAKAQAHINAG
CCCCCCCCCCEEEEECCEEEEEECCCCCCCCCCCCCEEEEEEECCCCCCCCHHEEEECCC
AKKVVISAPAGNDLKTIVYNVNHETLTADDQIISAASCTTNCLAPMAKALNDCATIESGI
CEEEEEECCCCCCCEEEEEECCCCEEECCHHHEEHHHHHHHHHHHHHHHHHHHHHHCCCC
MCTIHAYTGDQMILDGPQRKGDLRRSRAGACNIVPNSTGAAKAIGLVIPELNGKLIGAAQ
EEEEEEECCCEEEECCCCCCCHHHHHCCCEEEECCCCCCCCEEEEEEEECCCCEEEECHH
RVPTPTGSTTILNAVVAKKVTVDEVNAAMKAAATESFGYNTEQIVSSDIVGMRFGSLFDA
HCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCHHHHHHHHHHHH
TQTMVNELPNGGCQVQVVSWYDNENSYTSQMVRTIKYFAELN
HHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVKVAINGFGRIGRLAFRQMFGAEGYEVVAINDLTSPKMLAHLLKYDSSQGRYVNFGEE
EEEEEECCCCHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCEEECCCC
DQVTADDEAGTITVKGKTIKIYKEPDANNCPWGEIGVDVVLECSGFYTSKAKAQAHINAG
CCCCCCCCCCEEEEECCEEEEEECCCCCCCCCCCCCEEEEEEECCCCCCCCHHEEEECCC
AKKVVISAPAGNDLKTIVYNVNHETLTADDQIISAASCTTNCLAPMAKALNDCATIESGI
CEEEEEECCCCCCCEEEEEECCCCEEECCHHHEEHHHHHHHHHHHHHHHHHHHHHHCCCC
MCTIHAYTGDQMILDGPQRKGDLRRSRAGACNIVPNSTGAAKAIGLVIPELNGKLIGAAQ
EEEEEEECCCEEEECCCCCCCHHHHHCCCEEEECCCCCCCCEEEEEEEECCCCEEEECHH
RVPTPTGSTTILNAVVAKKVTVDEVNAAMKAAATESFGYNTEQIVSSDIVGMRFGSLFDA
HCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCHHHHHHHHHHHH
TQTMVNELPNGGCQVQVVSWYDNENSYTSQMVRTIKYFAELN
HHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10463150; 11466286 [H]