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The map label for this gene is aroB [H]

Identifier: 238917081

GI number: 238917081

Start: 1163780

End: 1164904

Strand: Reverse

Name: aroB [H]

Synonym: EUBELI_01151

Alternate gene names: 238917081

Gene position: 1164904-1163780 (Counterclockwise)

Preceding gene: 238917082

Following gene: 238917080

Centisome position: 54.33

GC content: 38.4

Gene sequence:

>1125_bases
ATGGGTGGCTGTTTAAGTATAAGAATAAGGGAGAATGTTATGAAGTGTATTAATGTAAAGTGCGAAGGAAAACCAGCATA
CGATATTGTGATTGAAAGTGGATTCGGGGGACTTTCAGAAGCCTTTAATAAGCTTGAAATAACAGGGAGAAAGTTATGTA
TTGTGACAGACAGCAATGTAGGTCCTTTATATGCAGAACAGGTAAAGAATGAACTTGAAAAAACAGGCAATGCAGTATAT
GTGTATACATTTGCAGCAGGAGAAGAGAATAAGACTCTTGACACAGTACAGGATGTATATGAATATCTTATAGAGAATCA
TTTTGACAGGAATGACTGCCTTGTAGCACTTGGCGGAGGAGTTGTTGGCGACCTTACAGGATTTTCTGCGGCAACATATC
TTAGAGGAATTAAATTCATACAGGTTCCTACGTCACTTCTTGCACAGGTTGATTCAAGTATTGGCGGCAAGACAGGCGTT
GATTTCAGGGCATATAAGAATATGGTTGGAGCATTCCATCAGCCAAAGCTTGTATATATGAACATGTCTGTGCTTAAGTC
ACTCAGTAAGAGACTTTTTAATTCTGGATTTGGTGAGATTATTAAGCATGGTCTTATTAAAGACAGGGAATATTACAACT
GGCTTAAGGACAATGCAGACAGAATTAAGGCACTAGATTCAGATGCACTTGAACATATGATATATGTGAGCTGTAACATC
AAGAGAGAGGTTGTTGAGAATGACCCTAGGGAAAAGGGTGAAAGAGCACTGCTTAATTTTGGACATACATTAGGACATGC
CATTGAAAAAGAGATGAACTTCTCACTTTATCATGGAGAGTGTGTTGTGCTTGGAATGATAGCAGCACTCAATATATGTG
TCGAGCTTGGAACTATAACTGCAGAGGAAAGAGATGATGCTCTTAAAACATTTGCATTATATGAATTCCCTGACCATGTC
ACAGGAATTAAGATTGATGATGTTGTTGCGGTATCTAAGAATGACAAGAAGATGGATGCCGGCAAGGTTAAGTTCATTCT
TCTTAAGTCAGTCGGAGATGCTTATATTGACAGAGATATAACTGATGACCAGATGAGAAGAGCACTTGAAGGTGTTATAA
GATAA

Upstream 100 bases:

>100_bases
CGGGTGATATTCCTGAGATAGTAACAGGAGGAATTGATCTTTCATCATTTAACAAGAATGAAAACAGATTTTAATTGATC
TTCACAGCCACCCACATATA

Downstream 100 bases:

>100_bases
ATGTTTAATAACGGAGGTCGAAAGTGAATAATAAAAAGAAAATATTTAATTTGTTATTTTATATTATAGGAATTGTTGTT
CTGACTGAATTAGACCAGAT

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 374; Mature: 373

Protein sequence:

>374_residues
MGGCLSIRIRENVMKCINVKCEGKPAYDIVIESGFGGLSEAFNKLEITGRKLCIVTDSNVGPLYAEQVKNELEKTGNAVY
VYTFAAGEENKTLDTVQDVYEYLIENHFDRNDCLVALGGGVVGDLTGFSAATYLRGIKFIQVPTSLLAQVDSSIGGKTGV
DFRAYKNMVGAFHQPKLVYMNMSVLKSLSKRLFNSGFGEIIKHGLIKDREYYNWLKDNADRIKALDSDALEHMIYVSCNI
KREVVENDPREKGERALLNFGHTLGHAIEKEMNFSLYHGECVVLGMIAALNICVELGTITAEERDDALKTFALYEFPDHV
TGIKIDDVVAVSKNDKKMDAGKVKFILLKSVGDAYIDRDITDDQMRRALEGVIR

Sequences:

>Translated_374_residues
MGGCLSIRIRENVMKCINVKCEGKPAYDIVIESGFGGLSEAFNKLEITGRKLCIVTDSNVGPLYAEQVKNELEKTGNAVY
VYTFAAGEENKTLDTVQDVYEYLIENHFDRNDCLVALGGGVVGDLTGFSAATYLRGIKFIQVPTSLLAQVDSSIGGKTGV
DFRAYKNMVGAFHQPKLVYMNMSVLKSLSKRLFNSGFGEIIKHGLIKDREYYNWLKDNADRIKALDSDALEHMIYVSCNI
KREVVENDPREKGERALLNFGHTLGHAIEKEMNFSLYHGECVVLGMIAALNICVELGTITAEERDDALKTFALYEFPDHV
TGIKIDDVVAVSKNDKKMDAGKVKFILLKSVGDAYIDRDITDDQMRRALEGVIR
>Mature_373_residues
GGCLSIRIRENVMKCINVKCEGKPAYDIVIESGFGGLSEAFNKLEITGRKLCIVTDSNVGPLYAEQVKNELEKTGNAVYV
YTFAAGEENKTLDTVQDVYEYLIENHFDRNDCLVALGGGVVGDLTGFSAATYLRGIKFIQVPTSLLAQVDSSIGGKTGVD
FRAYKNMVGAFHQPKLVYMNMSVLKSLSKRLFNSGFGEIIKHGLIKDREYYNWLKDNADRIKALDSDALEHMIYVSCNIK
REVVENDPREKGERALLNFGHTLGHAIEKEMNFSLYHGECVVLGMIAALNICVELGTITAEERDDALKTFALYEFPDHVT
GIKIDDVVAVSKNDKKMDAGKVKFILLKSVGDAYIDRDITDDQMRRALEGVIR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=351, Percent_Identity=40.1709401709402, Blast_Score=245, Evalue=4e-66,
Organism=Saccharomyces cerevisiae, GI6320332, Length=357, Percent_Identity=33.3333333333333, Blast_Score=185, Evalue=8e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 41597; Mature: 41466

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGCLSIRIRENVMKCINVKCEGKPAYDIVIESGFGGLSEAFNKLEITGRKLCIVTDSNV
CCCEEEEEEHHHHHHHHCCEECCCCCEEEEEECCCCCHHHHHHHEEECCCEEEEEECCCC
GPLYAEQVKNELEKTGNAVYVYTFAAGEENKTLDTVQDVYEYLIENHFDRNDCLVALGGG
CCHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCC
VVGDLTGFSAATYLRGIKFIQVPTSLLAQVDSSIGGKTGVDFRAYKNMVGAFHQPKLVYM
CEEHHCHHHHHHHHHCCEEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCEEEEE
NMSVLKSLSKRLFNSGFGEIIKHGLIKDREYYNWLKDNADRIKALDSDALEHMIYVSCNI
CHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHEEEEEEECC
KREVVENDPREKGERALLNFGHTLGHAIEKEMNFSLYHGECVVLGMIAALNICVELGTIT
CHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHCCCC
AEERDDALKTFALYEFPDHVTGIKIDDVVAVSKNDKKMDAGKVKFILLKSVGDAYIDRDI
CHHHHHHHHHHEEEECCCCCCCEEECCEEEECCCCCCCCCCCEEEEEEECCCHHHHCCCC
TDDQMRRALEGVIR
CHHHHHHHHHHHCC
>Mature Secondary Structure 
GGCLSIRIRENVMKCINVKCEGKPAYDIVIESGFGGLSEAFNKLEITGRKLCIVTDSNV
CCEEEEEEHHHHHHHHCCEECCCCCEEEEEECCCCCHHHHHHHEEECCCEEEEEECCCC
GPLYAEQVKNELEKTGNAVYVYTFAAGEENKTLDTVQDVYEYLIENHFDRNDCLVALGGG
CCHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCC
VVGDLTGFSAATYLRGIKFIQVPTSLLAQVDSSIGGKTGVDFRAYKNMVGAFHQPKLVYM
CEEHHCHHHHHHHHHCCEEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCEEEEE
NMSVLKSLSKRLFNSGFGEIIKHGLIKDREYYNWLKDNADRIKALDSDALEHMIYVSCNI
CHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHEEEEEEECC
KREVVENDPREKGERALLNFGHTLGHAIEKEMNFSLYHGECVVLGMIAALNICVELGTIT
CHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHCCCC
AEERDDALKTFALYEFPDHVTGIKIDDVVAVSKNDKKMDAGKVKFILLKSVGDAYIDRDI
CHHHHHHHHHHEEEECCCCCCCEEECCEEEECCCCCCCCCCCEEEEEEECCCHHHHCCCC
TDDQMRRALEGVIR
CHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA