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The map label for this gene is ygcA [C]

Identifier: 238917056

GI number: 238917056

Start: 1136390

End: 1137559

Strand: Reverse

Name: ygcA [C]

Synonym: EUBELI_01126

Alternate gene names: 238917056

Gene position: 1137559-1136390 (Counterclockwise)

Preceding gene: 238917057

Following gene: 238917054

Centisome position: 53.05

GC content: 37.78

Gene sequence:

>1170_bases
ATGACGAATAGATATGATGAGAAAGAAAGACGGATTCACTGTGCATTTTCAGAAAAATGCGGTGGCTGTGATTATGCCGG
GATGAAATATGACAATGAACTTGCAGTTAAGCAGAAGTACATTGAAGAACTTTTTGGCGAATATGTAAAAGTTGATGATA
TTGTAGGAATGTACAGACCAATACATTACCGCAATAAAGTTCATGCAGTTGTAGGACTTGATGATTCCAGAAATGTAATA
GCAGGAACCTACGAGGAAAACAGCCACAGAATAGTTGATACATCGGACTGTATGATTGAAGATTCACAGTGTACAGACAT
TATTAAGGATATTAAAGAACTAATAGCTTCATTTAAATATCAGCCATATGACGAAGATGCGGGAAAGGGAATGATCCGAC
ACATTCTTTTAAGAAAAGGATTTTCGACAAAGGAGATTATGCTTGTTATTGTTACAGCAGGAGTCGCATTTCCATCAAAG
AATAATTTTCTCAAGGTGTTATGTGAAAAGCATCCGAAAATTACTACGATTGTGCAGAATATTAACGACAGACGCACAAG
CATGGTGCTTGGAAATAGAAATATTGTTCTTAAGGGAAAAGGTTATATTGAGGATGTGCTGTGTGGCTGCAGGTTCAGAA
TAAGCCCGACATCATTCTATCAGATTAACCACCAGCAGACTGAAAAGCTGTACAAAAAGGCAATCCAGCTTGCTGATATA
TCAAAAAATGACACTGTAATTGATGCATATTGCGGAATTGGTACTATTGGAATAGTCGCCTCAAAAAAGGCTGGCAAAGT
TATAGGAGTTGAGCTTAATTCAGAAGCTGTATCAGATGCTAAGATAAATGCTTCAATTAACAATATAAAGAATGTCACAT
TTGTTAATGCTGACGCAGGAGATTTCCTTGTTGAGTATGCAAAAAATGCAAAGGCAGATGTTGTTATCATGGATCCGCCA
AGAAGCGGAAGCACACCGGAATTTCTTAATTCTCTTCTTAAGATTAAGCCAGACAGGATTGTGTACATTTCATGCGGACC
TGATACACAGGCAAGGGATATAAAGGTGCTGATTAAGGGTGGATATAAGGTTACGGCATGTCAGCCATTTGATTTGTTTC
CGCATACGGAGCATGTTGAAAATGTGATTTTATTGTCTCGAAAAGCTTAG

Upstream 100 bases:

>100_bases
ATGGGCGGTTGCCCTTTTGTGCGAGTAGCTAAGGCAAGACATAACGATAATCTTGAGTATGAGCTACAAGCATGAGGAGA
GATGAGGAGTTAAATATTTT

Downstream 100 bases:

>100_bases
GTTATGAAATTAAGGTAAGATTGGATATATAGCAATTTAATATAATAAGTATGGAAAGAACAGGTTGAAATATACCTGTT
TTTTTAGAAATAAAAAAAGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MTNRYDEKERRIHCAFSEKCGGCDYAGMKYDNELAVKQKYIEELFGEYVKVDDIVGMYRPIHYRNKVHAVVGLDDSRNVI
AGTYEENSHRIVDTSDCMIEDSQCTDIIKDIKELIASFKYQPYDEDAGKGMIRHILLRKGFSTKEIMLVIVTAGVAFPSK
NNFLKVLCEKHPKITTIVQNINDRRTSMVLGNRNIVLKGKGYIEDVLCGCRFRISPTSFYQINHQQTEKLYKKAIQLADI
SKNDTVIDAYCGIGTIGIVASKKAGKVIGVELNSEAVSDAKINASINNIKNVTFVNADAGDFLVEYAKNAKADVVIMDPP
RSGSTPEFLNSLLKIKPDRIVYISCGPDTQARDIKVLIKGGYKVTACQPFDLFPHTEHVENVILLSRKA

Sequences:

>Translated_389_residues
MTNRYDEKERRIHCAFSEKCGGCDYAGMKYDNELAVKQKYIEELFGEYVKVDDIVGMYRPIHYRNKVHAVVGLDDSRNVI
AGTYEENSHRIVDTSDCMIEDSQCTDIIKDIKELIASFKYQPYDEDAGKGMIRHILLRKGFSTKEIMLVIVTAGVAFPSK
NNFLKVLCEKHPKITTIVQNINDRRTSMVLGNRNIVLKGKGYIEDVLCGCRFRISPTSFYQINHQQTEKLYKKAIQLADI
SKNDTVIDAYCGIGTIGIVASKKAGKVIGVELNSEAVSDAKINASINNIKNVTFVNADAGDFLVEYAKNAKADVVIMDPP
RSGSTPEFLNSLLKIKPDRIVYISCGPDTQARDIKVLIKGGYKVTACQPFDLFPHTEHVENVILLSRKA
>Mature_388_residues
TNRYDEKERRIHCAFSEKCGGCDYAGMKYDNELAVKQKYIEELFGEYVKVDDIVGMYRPIHYRNKVHAVVGLDDSRNVIA
GTYEENSHRIVDTSDCMIEDSQCTDIIKDIKELIASFKYQPYDEDAGKGMIRHILLRKGFSTKEIMLVIVTAGVAFPSKN
NFLKVLCEKHPKITTIVQNINDRRTSMVLGNRNIVLKGKGYIEDVLCGCRFRISPTSFYQINHQQTEKLYKKAIQLADIS
KNDTVIDAYCGIGTIGIVASKKAGKVIGVELNSEAVSDAKINASINNIKNVTFVNADAGDFLVEYAKNAKADVVIMDPPR
SGSTPEFLNSLLKIKPDRIVYISCGPDTQARDIKVLIKGGYKVTACQPFDLFPHTEHVENVILLSRKA

Specific function: Could Be A 23s rRNA (Uracil-5-)-Methyltransferase. [C]

COG id: COG2265

COG function: function code J; SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI34222389, Length=350, Percent_Identity=28.2857142857143, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI51173878, Length=350, Percent_Identity=28.2857142857143, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI269784678, Length=207, Percent_Identity=29.4685990338164, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI269784680, Length=207, Percent_Identity=29.4685990338164, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI269784676, Length=207, Percent_Identity=29.4685990338164, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI20149688, Length=207, Percent_Identity=29.4685990338164, Blast_Score=102, Evalue=5e-22,
Organism=Escherichia coli, GI1789148, Length=397, Percent_Identity=26.1964735516373, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1787083, Length=381, Percent_Identity=24.1469816272966, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1790403, Length=190, Percent_Identity=28.9473684210526, Blast_Score=83, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71997438, Length=165, Percent_Identity=32.1212121212121, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322909, Length=169, Percent_Identity=29.585798816568, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24666579, Length=416, Percent_Identity=27.6442307692308, Blast_Score=157, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016027
- InterPro:   IPR001566
- InterPro:   IPR002792
- InterPro:   IPR010280 [H]

Pfam domain/function: PF01938 TRAM; PF05958 tRNA_U5-meth_tr [H]

EC number: NA

Molecular weight: Translated: 43610; Mature: 43479

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: PS01231 TRMA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNRYDEKERRIHCAFSEKCGGCDYAGMKYDNELAVKQKYIEELFGEYVKVDDIVGMYRP
CCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEHHHHHHHHCC
IHYRNKVHAVVGLDDSRNVIAGTYEENSHRIVDTSDCMIEDSQCTDIIKDIKELIASFKY
EEECCCEEEEEECCCCCCEEEEEEECCCCEEEECCCCEEECCHHHHHHHHHHHHHHHCCC
QPYDEDAGKGMIRHILLRKGFSTKEIMLVIVTAGVAFPSKNNFLKVLCEKHPKITTIVQN
CCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCEECCCCCCHHHHEECCCCCHHHHHHC
INDRRTSMVLGNRNIVLKGKGYIEDVLCGCRFRISPTSFYQINHQQTEKLYKKAIQLADI
CCCCCEEEEECCCEEEEECCCCHHHHHHCCEEEECCCEEEEECHHHHHHHHHHHHHHHCC
SKNDTVIDAYCGIGTIGIVASKKAGKVIGVELNSEAVSDAKINASINNIKNVTFVNADAG
CCCCCEEEECCCCCEEEEEECCCCCCEEEEEECCCCCCCEEEECCCCCCCEEEEEECCCH
DFLVEYAKNAKADVVIMDPPRSGSTPEFLNSLLKIKPDRIVYISCGPDTQARDIKVLIKG
HHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEEEEC
GYKVTACQPFDLFPHTEHVENVILLSRKA
CEEEEEECCCCCCCCHHHHCEEEEEEECC
>Mature Secondary Structure 
TNRYDEKERRIHCAFSEKCGGCDYAGMKYDNELAVKQKYIEELFGEYVKVDDIVGMYRP
CCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEHHHHHHHHCC
IHYRNKVHAVVGLDDSRNVIAGTYEENSHRIVDTSDCMIEDSQCTDIIKDIKELIASFKY
EEECCCEEEEEECCCCCCEEEEEEECCCCEEEECCCCEEECCHHHHHHHHHHHHHHHCCC
QPYDEDAGKGMIRHILLRKGFSTKEIMLVIVTAGVAFPSKNNFLKVLCEKHPKITTIVQN
CCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCEECCCCCCHHHHEECCCCCHHHHHHC
INDRRTSMVLGNRNIVLKGKGYIEDVLCGCRFRISPTSFYQINHQQTEKLYKKAIQLADI
CCCCCEEEEECCCEEEEECCCCHHHHHHCCEEEECCCEEEEECHHHHHHHHHHHHHHHCC
SKNDTVIDAYCGIGTIGIVASKKAGKVIGVELNSEAVSDAKINASINNIKNVTFVNADAG
CCCCCEEEECCCCCEEEEEECCCCCCEEEEEECCCCCCCEEEECCCCCCCEEEEEECCCH
DFLVEYAKNAKADVVIMDPPRSGSTPEFLNSLLKIKPDRIVYISCGPDTQARDIKVLIKG
HHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEEEEC
GYKVTACQPFDLFPHTEHVENVILLSRKA
CEEEEEECCCCCCCCHHHHCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]