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The map label for this gene is aroC

Identifier: 238916696

GI number: 238916696

Start: 767934

End: 769034

Strand: Direct

Name: aroC

Synonym: EUBELI_00758

Alternate gene names: 238916696

Gene position: 767934-769034 (Clockwise)

Preceding gene: 238916694

Following gene: 238916697

Centisome position: 35.81

GC content: 41.78

Gene sequence:

>1101_bases
ATGGCAGGTTCAGTGTTTGGAAATATATTTAAGATATCAACATGGGGAGAGTCGCATGGAGAGGGACTTGGAGTTGTAAT
TGACGGGTGTCCTGCAGGTCTGCCTCTTTGTGAGAAAGATATTCAGGAGCAGTTAGACAGAAGAAAACCAGGTCAGTCAA
AGTTTACTACACCAAGAAAGGAAGATGATGAAGTACATATTCTTTCAGGTGTATTTGAAGGCAAGACTACCGGGACTCCA
ATATCACTTGCCGTATATAATAAGACACAGAGGTCTGCTGACTATTCAGAGATAGCTAATTATTACAGACCGGGACATGC
TGATTATACATTTGACGAGAAATTCGGATTCAGGGATTACAGAGGCGGAGGAAGAAGTTCTGGAAGAGAAACTATCGGAA
GAGTTGCAGCCGGTGCAATCGCTATGAAGATTCTTAAAGAGCTTGGAATTAATATTACAGCATATGCTAAAGAAATCGGT
GGAATTGGCATTGATTATGATAAGTTTGATATAGCTGAAAGAGATAATAACGCATTTAACATGCCTGATAAGGAAGCTGC
AGAGAAGGTTAAGGCTTTTGCAGAGAGCAAGATGTCAGTTGGAGATTCAATCGGTGGTGTCATTGAATGCAGGGTTACAG
GCATGATGACTGGAATTGGCAATCCTACATTTGAAAAGCTAGATGCTAATCTTGCTAAGGCAATAATGTCAATCGGGGCT
GTCAAAGGCTTTGAGATTGGAGACGGGTTTGAAGCGGCTAAAGTTACAGGAAAGTATAATAATGATGAATTCGTAATGAA
GGATGGCAGGGTTGGTAAGCTGACTAATCACAGCGGCGGAGTGCTTGGCGGAATAAGCGACGGTGATGAGATTGTGTTCA
GGGCAGCGGTAAAACCGACACCTTCAATTAGTGCATTGCAGGAAACTGTTAATAAGCAGGGCGAGGATATCGAGGTTTCA
ATCAAAGGAAGACATGACCCGATGATAGTTCCAAGAGCAGTTGTTGTGGTTGAAGCTATGACAGCACTTACACTTGTTGA
CCTGATATTTGACAATATGACGGCTAGAATGGACAGAGTTAAAGAGTTTTATAGAAAATAA

Upstream 100 bases:

>100_bases
AATAAAAATAAGAAAAAATTAATAAATTGGGGTTTTGCTTGATGATATATATTTTAATATGTTAAAATAAATCCTATTGA
AAAGATGAGGAGAATATATT

Downstream 100 bases:

>100_bases
AAGGAGCAGATATGTATAAAATTTTAAAGACAGATGGCAGGGCAAAAAGAGCAGAGTTCACAACAGTACATGGAACTGTG
CAGACACCTGTATTTATGAA

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MAGSVFGNIFKISTWGESHGEGLGVVIDGCPAGLPLCEKDIQEQLDRRKPGQSKFTTPRKEDDEVHILSGVFEGKTTGTP
ISLAVYNKTQRSADYSEIANYYRPGHADYTFDEKFGFRDYRGGGRSSGRETIGRVAAGAIAMKILKELGINITAYAKEIG
GIGIDYDKFDIAERDNNAFNMPDKEAAEKVKAFAESKMSVGDSIGGVIECRVTGMMTGIGNPTFEKLDANLAKAIMSIGA
VKGFEIGDGFEAAKVTGKYNNDEFVMKDGRVGKLTNHSGGVLGGISDGDEIVFRAAVKPTPSISALQETVNKQGEDIEVS
IKGRHDPMIVPRAVVVVEAMTALTLVDLIFDNMTARMDRVKEFYRK

Sequences:

>Translated_366_residues
MAGSVFGNIFKISTWGESHGEGLGVVIDGCPAGLPLCEKDIQEQLDRRKPGQSKFTTPRKEDDEVHILSGVFEGKTTGTP
ISLAVYNKTQRSADYSEIANYYRPGHADYTFDEKFGFRDYRGGGRSSGRETIGRVAAGAIAMKILKELGINITAYAKEIG
GIGIDYDKFDIAERDNNAFNMPDKEAAEKVKAFAESKMSVGDSIGGVIECRVTGMMTGIGNPTFEKLDANLAKAIMSIGA
VKGFEIGDGFEAAKVTGKYNNDEFVMKDGRVGKLTNHSGGVLGGISDGDEIVFRAAVKPTPSISALQETVNKQGEDIEVS
IKGRHDPMIVPRAVVVVEAMTALTLVDLIFDNMTARMDRVKEFYRK
>Mature_365_residues
AGSVFGNIFKISTWGESHGEGLGVVIDGCPAGLPLCEKDIQEQLDRRKPGQSKFTTPRKEDDEVHILSGVFEGKTTGTPI
SLAVYNKTQRSADYSEIANYYRPGHADYTFDEKFGFRDYRGGGRSSGRETIGRVAAGAIAMKILKELGINITAYAKEIGG
IGIDYDKFDIAERDNNAFNMPDKEAAEKVKAFAESKMSVGDSIGGVIECRVTGMMTGIGNPTFEKLDANLAKAIMSIGAV
KGFEIGDGFEAAKVTGKYNNDEFVMKDGRVGKLTNHSGGVLGGISDGDEIVFRAAVKPTPSISALQETVNKQGEDIEVSI
KGRHDPMIVPRAVVVVEAMTALTLVDLIFDNMTARMDRVKEFYRK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=351, Percent_Identity=49.5726495726496, Blast_Score=322, Evalue=2e-89,
Organism=Saccharomyces cerevisiae, GI6321290, Length=377, Percent_Identity=44.2970822281167, Blast_Score=309, Evalue=5e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_EUBE2 (C4Z562)

Other databases:

- EMBL:   CP001104
- RefSeq:   YP_002930213.1
- ProteinModelPortal:   C4Z562
- GeneID:   7957306
- GenomeReviews:   CP001104_GR
- KEGG:   eel:EUBELI_00758
- OMA:   SRFTTQR
- ProtClustDB:   PRK05382
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 39633; Mature: 39502

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGSVFGNIFKISTWGESHGEGLGVVIDGCPAGLPLCEKDIQEQLDRRKPGQSKFTTPRK
CCCCCCCCEEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCC
EDDEVHILSGVFEGKTTGTPISLAVYNKTQRSADYSEIANYYRPGHADYTFDEKFGFRDY
CCCCEEEEEEEECCCCCCCCEEEEEECCHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCC
RGGGRSSGRETIGRVAAGAIAMKILKELGINITAYAKEIGGIGIDYDKFDIAERDNNAFN
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHCCCCCCCCCCCCCCCCCCCCC
MPDKEAAEKVKAFAESKMSVGDSIGGVIECRVTGMMTGIGNPTFEKLDANLAKAIMSIGA
CCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHC
VKGFEIGDGFEAAKVTGKYNNDEFVMKDGRVGKLTNHSGGVLGGISDGDEIVFRAAVKPT
CCCCCCCCCCCEEEEECCCCCCEEEEECCCEEEECCCCCCEEECCCCCCEEEEEEECCCC
PSISALQETVNKQGEDIEVSIKGRHDPMIVPRAVVVVEAMTALTLVDLIFDNMTARMDRV
CCHHHHHHHHHCCCCEEEEEEECCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEFYRK
HHHHCC
>Mature Secondary Structure 
AGSVFGNIFKISTWGESHGEGLGVVIDGCPAGLPLCEKDIQEQLDRRKPGQSKFTTPRK
CCCCCCCEEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCC
EDDEVHILSGVFEGKTTGTPISLAVYNKTQRSADYSEIANYYRPGHADYTFDEKFGFRDY
CCCCEEEEEEEECCCCCCCCEEEEEECCHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCC
RGGGRSSGRETIGRVAAGAIAMKILKELGINITAYAKEIGGIGIDYDKFDIAERDNNAFN
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHCCCCCCCCCCCCCCCCCCCCC
MPDKEAAEKVKAFAESKMSVGDSIGGVIECRVTGMMTGIGNPTFEKLDANLAKAIMSIGA
CCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHC
VKGFEIGDGFEAAKVTGKYNNDEFVMKDGRVGKLTNHSGGVLGGISDGDEIVFRAAVKPT
CCCCCCCCCCCEEEEECCCCCCEEEEECCCEEEECCCCCCEEECCCCCCEEEEEEECCCC
PSISALQETVNKQGEDIEVSIKGRHDPMIVPRAVVVVEAMTALTLVDLIFDNMTARMDRV
CCHHHHHHHHHCCCCEEEEEEECCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEFYRK
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA